-
公开(公告)号：US20160033681A1
公开(公告)日：2016-02-04
申请号：US14813728
申请日：2015-07-30
Applicant: University of Houston System
Inventor： Wei-Chuan Shih , Yu-Lung Sung
CPC classification number: G02B1/041 , B29D11/00365 , B29D11/00442 , B29D11/0073 , B29K2083/00 , B29K2105/16 , B29K2995/002 , B29K2995/0026 , B29K2995/0031 , G02B21/02 , C08L83/04
Abstract: A lithography-free, mold-free, single-step method of fabricating high quality optical lenses by curing polydimethylsiloxane (PDMS) droplets on a pre-heated smooth surface allows lenses with different focal lengths to be made by varying the droplet volume and surface temperature.
Abstract translation: 通过在预加热的光滑表面上固化聚二甲基硅氧烷（PDMS）液滴制造高质量光学透镜的无光刻，无模制的单步法允许通过改变液滴体积和表面温度来制造具有不同焦距的透镜 。
-
公开(公告)号：US10661347B2
公开(公告)日：2020-05-26
申请号：US15840765
申请日：2017-12-13
Applicant: University of Houston System
Inventor： Wei-Chuan Shih
Abstract: A nanoporous gold disk (NPGD) as a novel surface-enhanced Raman spectroscopy (SERS) substrate. NPGD has SERS enhancement factor similar to that of gold nanoshells, but allows, for example, at least three times more benzenethiol molecules to be attached to its surface due to large surface-to-volume ratio. The high capacity enables the rapid detection of attomole-level benzenethiol molecules with relatively high detector temperatures. Additionally, a fabrication process to make NPGD with controlled size and highly reproducible SERS activities.
-
Patent Agency Ranking
公开(公告)号：US20180154450A1
公开(公告)日：2018-06-07
申请号：US15840765
申请日：2017-12-13
Applicant: University of Houston System
Inventor： Wei-Chuan Shih
CPC classification number: B22F9/16 , B22F1/0044 , G01N21/658
Abstract: A nanoporous gold disk (NPGD) as a novel surface-enhanced Raman spectroscopy (SERS) substrate. NPGD has SERS enhancement factor similar to that of gold nanoshells, but allows, for example, at least three times more benzenethiol molecules to be attached to its surface due to large surface-to-volume ratio. The high capacity enables the rapid detection of attomole-level benzenethiol molecules with relatively high detector temperatures. Additionally, a fabrication process to make NPGD with controlled size and highly reproducible SERS activities.
-
公开(公告)号：US09873152B2
公开(公告)日：2018-01-23
申请号：US13796201
申请日：2013-03-12
Applicant: The University of Houston System
Inventor： Wei-Chuan Shih
CPC classification number: B22F9/16 , B22F1/0044 , G01N21/658
Abstract: A nanoporous gold disk (NPGD) as a novel surface-enhanced Raman spectroscopy (SERS) substrate. NPGD has SERS enhancement factor similar to that of gold nanoshells, but allows, for example, at least three times more benzenethiol molecules to be attached to its surface due to large surface-to-volume ratio. The high capacity enables the rapid detection of attomole-level benzenethiol molecules with relatively high detector temperatures. Additionally, a fabrication process to make NPGD with controlled size and highly reproducible SERS activities.
-
15.发明授权Method of stamping surface-enhance Raman spectroscopy for label-free, multiplexed, molecular sensing and imaging 有权冲压表面增强拉曼光谱的方法，用于无标签，多路复用，分子检测和成像公开(公告)号：US09546958B2
公开(公告)日：2017-01-17
申请号：US14699025
申请日：2015-04-29
Applicant: UNIVERSITY OF HOUSTON SYSTEM
Inventor： Wei-Chuan Shih
CPC classification number: G01N21/658 , B82Y30/00 , G01J3/02 , G01J3/44
Abstract: The present disclosure relates the use of a stamping surface enhanced Raman scattering (S-SERS) technique with nanoporous gold disk (NPGD) plasmonic substrates to produce a label-free, multiplexed molecular sensing and imaging technique. A NPGD SERS substrate is stamped onto a surface containing one or more target molecules, followed by SERS measurement of the target molecules located between the surface and SERS substrate. The target molecules may be deposited on the surface, which may be a carrier substrate such as polydimethylsiloxane (PDMS).
Abstract translation: 本公开内容涉及冲压表面增强拉曼散射（S-SERS）技术与纳米多孔金盘（NPGD）等离子体激元基板的使用以产生无标记的复合分子感测和成像技术。 将NPGD SERS底物冲压到含有一种或多种靶分子的表面上，随后对位于表面和SERS底物之间的靶分子进行SERS测量。 靶分子可以沉积在表面上，其可以是载体基底如聚二甲基硅氧烷（PDMS）。
-
16.发明申请METHOD OF STAMPING SURFACE-ENHANCE RAMAN SPECTROSCOPY FOR LABEL-FREE, MULTIPLEXED, MOLECULAR SENSING AND IMAGING 有权用于无标签，多路复用，分子感测和成像的表面加强拉曼光谱的方法公开(公告)号：US20150308960A1
公开(公告)日：2015-10-29
申请号：US14699025
申请日：2015-04-29
Applicant: UNIVERSITY OF HOUSTON SYSTEM
Inventor： Wei-Chuan Shih
IPC: G01N21/65
CPC classification number: G01N21/658 , B82Y30/00 , G01J3/02 , G01J3/44
Abstract: The present disclosure relates the use of a stamping surface enhanced Raman scattering (S-SERS) technique with nanoporous gold disk (NPGD) plasmonic substrates to produce a label-free, multiplexed molecular sensing and imaging technique. A NPGD SERS substrate is stamped onto a surface containing one or more target molecules, followed by SERS measurement of the target molecules located between the surface and SERS substrate. The target molecules may be deposited on the surface, which may be a carrier substrate such as polydimethylsiloxane (PDMS).
Abstract translation: 本公开内容涉及冲压表面增强拉曼散射（S-SERS）技术与纳米多孔金盘（NPGD）等离子体激元基板的使用以产生无标记的复合分子感测和成像技术。 将NPGD SERS底物冲压到含有一种或多种靶分子的表面上，随后对位于表面和SERS底物之间的靶分子进行SERS测量。 靶分子可以沉积在表面上，其可以是载体基底如聚二甲基硅氧烷（PDMS）。
-
17.发明授权公开(公告)号：US08902421B2
公开(公告)日：2014-12-02
申请号：US13741277
申请日：2013-01-14
Applicant: The University of Houston System
Inventor： Wei-Chuan Shih
CPC classification number: G01J3/44 , G01J3/0229
Abstract: An active-illumination parallel Raman microspectroscopy scheme for simultaneously collecting Raman spectra from multiple points in a full-spectra range. A combination of multi-point laser illumination with wide-field Raman imaging is employed in order to allow for simultaneous imaging of multiple points not aligned on a single line.
Abstract translation: 一种主动照明平行拉曼显微光谱方案，用于同时从全谱范围的多个点收集拉曼光谱。 采用多点激光照明与广域拉曼成像技术的组合，以便同时成像不排列在一条线上的多个点。
-
-
-
-
-
-
Search Results
17
records
(took 0.018 seconds)
