公开(公告)号：US09535053B1

公开(公告)日：2017-01-03

申请号：US15015231

申请日：2016-02-04

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/48 ,  G01N33/49 ,  G01N21/31 ,  G01N21/25

CPC classification number: G01N33/492 ,  G01J3/00 ,  G01N21/255 ,  G01N21/31 ,  G01N2201/062

Abstract: A system of measuring hemoglobin and bilirubin parameters in a whole blood sample using optical absorbance. The system includes an optical-sample module, a spectrometer module, an optical fiber module optically connecting the optical-sample module to the spectrometer module, and a processor module. The optical-sample module has a light-emitting module having a LED light source, a cuvette and a calibrating-light module. The processor module receives and processes an electrical signal from the spectrometer module and transforms the electrical signal into an output signal useable for displaying and reporting hemoglobin parameter values and/or total bilirubin parameter values for the whole blood sample.

Abstract translation: 使用光吸收测量全血样品中血红蛋白和胆红素参数的系统。 该系统包括光学样本模块，光谱仪模块，将光学样本模块光学连接到光谱仪模块的光纤模块以及处理器模块。 光学样本模块具有具有LED光源，比色皿和校准光模组的发光模块。 处理器模块接收并处理来自光谱仪模块的电信号，并将电信号转换成可用于显示和报告全血样品的血红蛋白参数值和/或总胆红素参数值的输出信号。

公开(公告)号：US20160186558A1

公开(公告)日：2016-06-30

申请号：US14760343

申请日：2014-05-30

Applicant: Halliburton Energy Services, Inc.

Inventor： Robert Paul Freese ,  Tian He ,  Christopher Michael Jones

IPC: E21B49/08 ,  G01N21/84

CPC classification number: E21B49/08 ,  E21B47/00 ,  E21B2049/085 ,  G01J3/00 ,  G01N21/31 ,  G01N21/84 ,  G01N21/85 ,  G01V8/00 ,  G01V8/10

Abstract: Disclosed is the detection of emulsions and microdispersions with an optical computing device. One disclosed method includes emitting electromagnetic radiation from an electromagnetic radiation source, optically interacting the electromagnetic radiation with a fluid and thereby generating fluid interacted radiation, detecting a portion of the fluid interacted radiation with a reference detector arranged within an optical channel of an optical computing device, generating a reference signal with the reference detector, and determining an emulsive state of the fluid based on the reference signal.

Abstract translation: 公开了使用光学计算装置检测乳液和微分散体。 一种公开的方法包括从电磁辐射源发射电磁辐射，将电磁辐射与流体光学相互作用，从而产生流体相互作用的辐射，用设置在光学计算装置的光学通道内的参考检测器检测流体相互作用的辐射的一部分 ，用参考检测器产生参考信号，以及基于参考信号确定流体的乳化状态。

公开(公告)号：US20160161705A1

公开(公告)日：2016-06-09

申请号：US14957528

申请日：2015-12-02

Applicant: MarqMetrix, Inc.

Inventor： Brian James Marquardt ,  John Scott Van Vuren

IPC: G02B7/14 ,  G01N21/65 ,  G02B7/02

CPC classification number: G02B7/14 ,  G01J3/00 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0291 ,  G01N21/15 ,  G01N21/65 ,  G01N2021/015 ,  G01N2021/656 ,  G01N2201/0221 ,  G01N2201/0245 ,  G01N2201/065 ,  G02B7/027

Abstract: Examples embodiments of a removable optical assembly are disclosed. A removable optical assembly can be removably attached to a probe of an optical analytical instrument. The removable optical assembly can comprise a spherical optical element. An embodiment of the removable optical assembly can allow contact interrogation of a sample. In some embodiments, the removable optical assembly can comprise an internal optical element. In other embodiments, the removable optical assembly can comprise an external optical element. Manufacture of the removable optical assembly can comprise a monolithic embodiment or an assembled embodiment comprising a plurality of subassemblies. Embodiments of the removable optical assembly can be conical, cylindrical or planar is shape. The removable optical assembly can, in some embodiments, be consumable and/or disposable.

Abstract translation: 公开了可拆卸光学组件的示例实施例。 可拆卸的光学组件可以可移除地附接到光学分析仪器的探针。 可拆卸的光学组件可以包括球面光学元件。 可拆卸光学组件的实施例可以允许接触询问样品。 在一些实施例中，可拆卸光学组件可以包括内部光学元件。 在其他实施例中，可拆卸光学组件可以包括外部光学元件。 可拆卸光学组件的制造可以包括整体实施例或包括多个子组件的组装实施例。 可拆卸光学组件的实施例可以是圆锥形，圆柱形或平面形。 在一些实施例中，可拆卸的光学组件可以是可消耗的和/或一次性的。

公开(公告)号：US20150362427A1

公开(公告)日：2015-12-17

申请号：US14306228

申请日：2014-06-17

Applicant: Vlad Joseph Novotny

Inventor： Vlad Joseph Novotny

IPC: G01N21/3577 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/39

CPC classification number: A61B5/1455 ,  A61B5/00 ,  A61B5/0075 ,  A61B5/14532 ,  G01J3/00 ,  G01J3/0205 ,  G01J3/108 ,  G01J3/42 ,  G01J3/433 ,  G01J3/45 ,  G01J2003/1213 ,  G01N21/39 ,  G01N21/4738 ,  G01N21/49 ,  G01N2021/3595

Abstract: Multiple optical architectures based on photosensitive arrays are disclosed. The optical engines collect five dimensional data from the samples with three dimensional spatial information and temporal and spectral information simultaneously, in parallel from all channels, without optical scanning. The photosensitive arrays and/or last component of illumination system are in contact or close proximity of the sample surface. The application of optical engines to sensitive detection of species of interest in the complex reflecting and scattering matrix with the high concentration of interfering species is described. The optical engines are applicable to noninvasive, mobile monitoring of various species of interest in vivo and in vitro.

Abstract translation: 公开了基于光敏阵列的多种光学架构。 光学引擎从具有三维空间信息和时间和频谱信息的样本中收集五维数据，与所有通道并行，而无需光学扫描。 光敏阵列和/或照明系统的最后部件与样品表面接触或接近。 描述了光引擎在具有高浓度干扰物质的复反射和散射基质中敏感检测感兴趣物种的应用。 光学引擎适用于体内和体外各种感兴趣物种的无创移动监测。

公开(公告)号：US20150346087A1

公开(公告)日：2015-12-03

申请号：US14408725

申请日：2011-12-20

Applicant: HALLIBURTON ENERGY SERVICES, INC.

Inventor： Neal G. Skinner

IPC: G01N21/31 ,  G01N21/27

CPC classification number: G01N21/31 ,  G01J3/00 ,  G01J3/2803 ,  G01J3/32 ,  G01J2003/1226 ,  G01N21/255 ,  G01N21/27 ,  G01N21/314 ,  G01N21/552 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/12 ,  G01N2201/1296 ,  G02B5/285

Abstract: Optical computing devices including a light source that emits electromagnetic radiation into an optical train extending from the light source to a detector, a substance arranged in the optical train and configured to optically interact with the electromagnetic radiation and produce sample interacted radiation, a processor array arranged in the optical train and including a plurality of ICE arranged on a substrate and configured to optically interact with the electromagnetic radiation. The detector receives modified electromagnetic radiation generated through optical interaction of the electromagnetic radiation with the substance and the processor array. A weighting device is coupled to one or more of the ICE to optically apply a weighting factor to the modified electromagnetic radiation prior to being received by the detector, wherein the detector generates an output signal indicative of a characteristic of the substance based on beams of modified electromagnetic radiation.

Abstract translation: 光学计算设备，包括将电磁辐射发射到从光源延伸到检测器的光学系列中的光源，布置在光学系列中并被配置为与电磁辐射光学相互作用并产生样品相互作用的辐射的物质;布置的处理器阵列 并且包括布置在基板上并被配置为与电磁辐射光学相互作用的多个ICE。 检测器接收通过电磁辐射与物质和处理器阵列的光学相互作用产生的修改的电磁辐射。 加权装置耦合到ICE中的一个或多个，以在由检测器接收之前将加权因子光学地应用于修改的电磁辐射，其中，所述检测器基于经修改的光束来生成指示所述物质的特征的输出信号 电磁辐射。

公开(公告)号：US20150002845A1

公开(公告)日：2015-01-01

申请号：US13927683

申请日：2013-06-26

Applicant: General Electric Company

Inventor： Victor Petrovich Ostroverkhov ,  Dmitry Vladimirovich Dylov ,  Siavash Yazdanfar ,  Stephen B. Solomon

IPC: G01B11/14 ,  A61B10/02

CPC classification number: A61B10/02 ,  G01B11/002 ,  G01J3/00 ,  G01N21/31 ,  G01N21/65 ,  G01N2021/6417

Abstract: A spectroscopy system for auto-aligning a biopsy collecting device is presented. The spectroscopy system includes an illumination subsystem configured to emit an illumination light towards the biopsy collecting device, whereas the biopsy collecting device includes an activator unit and a needle unit and wherein the needle unit includes a cannula and a stylet having a biopsy specimen. Also, the spectroscopy system includes a fixation subsystem capable of holding the biopsy collecting device and configured to place the needle unit comprising the biopsy specimen across the illumination light. Further, the spectroscopy system includes a detection subsystem configured to receive a light comprising at least one of an attenuated illumination light and a re-emitted light from the needle unit. In addition, the detection subsystem is configured to send a control signal to align the needle unit at a predetermined position in the spectroscopy system based on the received light.

Abstract translation: 提出了一种用于自动对准活检收集装置的光谱系统。 光谱系统包括被配置为朝向活检收集装置发射照明光的照明子系统，而活检收集装置包括激活器单元和针单元，并且其中针单元包括插管和具有活检样本的探针。 此外，光谱系统包括固定子系统，其能够保持活检收集装置并且构造成将包括活检标本的针单元放置在照明光上。 此外，光谱系统包括被配置为接收包括衰减照明光和来自针单元的再发射光中的至少一种的光的检测子系统。 此外，检测子系统被配置为发送控制信号，以根据所接收的光将针单元对准在光谱系统中的预定位置。

公开(公告)号：US08914242B2

公开(公告)日：2014-12-16

申请号：US13136079

申请日：2011-07-21

Applicant: Tom Lee Erb

Inventor： Tom Lee Erb

IPC: G01N23/02 ,  G01J3/00 ,  G06F19/00 ,  G06F17/40 ,  G01R23/16 ,  G01N22/04 ,  G01R27/26

CPC classification number: G01R23/16 ,  G01J3/00 ,  G01N22/04 ,  G01N23/02 ,  G01R27/2623 ,  G06F17/40 ,  G06F19/00 ,  G06F2219/00

Abstract: The present invention includes a guided microwave spectroscopy system (1) that eliminates the need for an automatic gain control feature by providing multiple signal processing paths having differing fixed voltage gains. An emitted signal which exits a test chamber (2) containing a material under test is simultaneously amplified by at least a first fixed gain amplifier (4) and a second fixed gain amplifier (7). The output signal of each amplifier is separately digitized and then normalized for further digital signal processing by a computer (13) in order to determine parameters of the material under test which may have variable microwave radiation characteristics that are a function of the frequency of the signal emitted into the test chamber. During the signal processing step a system clock (121) causes the computer to sample only an integral number of complete output signal cycles. A calibration protocol (136-154) is conducted based on laboratory samples of each potential material to be processed by the system (1).

Abstract translation: 本发明包括一种通过提供具有不同固定电压增益的多个信号处理路径来消除对自动增益控制特征的需要的导向微波光谱系统（1）。 离开包含待测材料的测试室（2）的发射信号由至少第一固定增益放大器（4）和第二固定增益放大器（7）同时放大。 每个放大器的输出信号被分开地数字化，然后被归一化用于由计算机（13）进一步的数字信号处理，以便确定待测材料的参数，其可以具有作为信号频率的函数的可变微波辐射特性 发射到测试室。 在信号处理步骤期间，系统时钟（121）使得计算机只对整数个完整的输出信号周期进行采样。 基于由系统（1）处理的每个潜在材料的实验室样品，进行校准协议（136-154）。

公开(公告)号：US20130194571A1

公开(公告)日：2013-08-01

申请号：US13363490

申请日：2012-02-01

Applicant: Scott Thomas Sanders

Inventor： Scott Thomas Sanders

IPC: G01J3/28 ,  C03B37/01 ,  G02B6/00

CPC classification number: G02B6/00 ,  G01J3/00 ,  G01J3/0218 ,  G01J3/42 ,  G01N21/31 ,  G01N21/8507 ,  G01N2021/8528 ,  G01N2021/8578 ,  G01N2201/084 ,  G02B6/262

Abstract: A remote sensor element for spectrographic measurements employs a monolithic assembly of one or two fiber optics to two optical elements separated by a supporting structure to allow the flow of gases or particulates therebetween. In a preferred embodiment, the sensor element components are fused ceramic to resist high temperatures and failure from large temperature changes.

Abstract translation: 用于光谱测量的远程传感器元件使用一个或两个光纤的单片组件到由支撑结构隔开的两个光学元件，以允许其间的气体或微粒的流动。 在优选实施例中，传感器元件部件是熔融陶瓷以抵抗高温度和从较大温度变化引起的故障。

公开(公告)号：US20130176553A1

公开(公告)日：2013-07-11

申请号：US13682010

申请日：2012-11-20

Applicant: PIONEER HI-BRED INTERNATIONAL, INC.

Inventor： Jason Cope ,  David Kurth

IPC: G01J3/00 ,  G01N1/04 ,  G01B11/00 ,  G01N23/04 ,  G01N21/31 ,  G01R33/44 ,  G01N3/40 ,  B01L3/00 ,  G01J3/46

CPC classification number: A01C1/025 ,  B01L3/50 ,  G01B11/00 ,  G01J3/00 ,  G01J3/46 ,  G01N1/04 ,  G01N3/40 ,  G01N21/314 ,  G01N21/33 ,  G01N21/3563 ,  G01N21/359 ,  G01N23/04 ,  G01N33/0098 ,  G01N35/0099 ,  G01R33/44

Abstract: The present invention provides a method and apparatus for non-destructive testing of a seed. In various embodiments, the method may comprise vibrating the seed to orient the seed on an axis, identifying a location of a known feature of the seed, determining a sample location on the seed based on the location of the known feature, and performing a non-destructive testing procedure on the seed proximate the sample location. In one embodiment, the method may comprise removing a sample portion of the seed from the sample location without damaging the embryo of the seed. Accordingly, the viability of the seed may be maintained while allowing for subsequent testing on the sample portion of the seed.

Abstract translation: 本发明提供一种用于种子无损检测的方法和装置。 在各种实施例中，该方法可以包括振动种子以在轴上定向​​种子，识别种子的已知特征的位置，基于已知特征的位置确定种子上的样本位置，以及执行非 在样品位置附近的种子上的破坏性测试程序。 在一个实施方案中，该方法可以包括从样品位置移除种子的样品部分而不损害种子的胚胎。 因此，可以保持种子的存活力，同时允许对种子的样品部分的后续测试。

公开(公告)号：US20120154803A1

公开(公告)日：2012-06-21

申请号：US13316767

申请日：2011-12-12

Applicant: Yuya MIYAZONO

Inventor： Yuya MIYAZONO

IPC: G01J3/28

CPC classification number: G01J3/00 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/28 ,  G01J3/2803

Abstract: A spectroscopic detector includes a spectroscopic element for dispersing light, a photodetector for detecting the light dispersed by the spectroscopic element and a condensing optical system for condensing the dispersed light to the photodetector and compensating for a deviation in a detected wavelength deriving from nonlinearity of the angle of emergence generated in the spectroscopic element through chromatic aberration of magnification.

Abstract translation: 分光检测器包括用于分散光的分光元件，用于检测由分光元件分散的光的光电检测器和用于将分散的光聚集到光电检测器的聚光系统，并补偿由角度的非线性引起的检测波长的偏差 通过色像差产生在分光元件中的出现。