公开(公告)号：US12114973B2

公开(公告)日：2024-10-15

申请号：US17579525

申请日：2022-01-19

Applicant: Fresenius Medical Care Holdings, Inc.

Inventor： Louis LeeGrande Barrett

IPC: A61B5/1455 ,  G01J1/02 ,  G01J3/02 ,  G01J3/28 ,  G01J3/42 ,  G01N15/06 ,  G01N21/27 ,  G01N21/31 ,  G01N21/3577 ,  G01N33/49 ,  A61B5/00 ,  G01J1/44 ,  G01N15/01 ,  G01N15/075

CPC classification number: A61B5/1455 ,  A61B5/14557 ,  G01J1/0214 ,  G01J3/0205 ,  G01J3/28 ,  G01J3/42 ,  G01N15/06 ,  G01N21/274 ,  G01N21/314 ,  G01N21/3577 ,  G01N33/49 ,  A61B5/0022 ,  A61B2560/0223 ,  G01J2001/444 ,  G01N15/01 ,  G01N15/075 ,  G01N2201/062 ,  G01N2201/0624

Abstract: A measurement system for measuring blood characteristics includes a controller, an emitter, a sensor, and a reference sensor. The emitter emits light at a plurality of wavelengths from a first side of a blood flow channel to a second side of the blood flow channel. The sensor is provided on the second side of the blood flow channel. The reference sensor is provided on the first side of the blood flow channel. The controller compensates measurements from the sensor based upon measurements from the reference sensor. The reference sensor may be disposed in a position to increase noise immunity of the measurement system. The measurement system may be connected to or part of a dialysis system.

公开(公告)号：US20240180428A1

公开(公告)日：2024-06-06

申请号：US18438144

申请日：2024-02-09

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61C1/00 ,  A61C19/04 ,  G01J3/02 ,  G01J3/10 ,  G01J3/12 ,  G01J3/14 ,  G01J3/18 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/95 ,  G01N33/02 ,  G01N33/15 ,  G01N33/44 ,  G01N33/49 ,  G16H40/67 ,  G16Z99/00 ,  H01S3/00 ,  H01S3/067 ,  H01S3/30

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61C19/04 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01N21/35 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G16H40/67 ,  G16Z99/00 ,  A61B5/0024 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  A61C1/0046 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J3/1838 ,  G01J2003/2826 ,  G01M3/38 ,  G01N2021/3513 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N21/85 ,  G01N21/9508 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302 ,  Y02A90/10

Abstract: An optical system comprises a wearable device for measuring one or more physiological parameters. The physiological parameters may change in response to stretching of the hand or movement of fingers or thumb of the user, or the parameters may be related to blood constituents or blood flow. The wearable device comprises a light source with a plurality of semiconductor diodes and a detection system that measures reflected light from tissue comprising skin. The semiconductor diodes may be light emitting diodes or laser diodes. The signal to noise ratio for the output signal may be improved by synchronizing the detection system to the light source, increasing light intensity of at least one of the plurality of semiconductor diodes from an initial light intensity, and using change detection that compares light on versus light off for the detection system output. The wearable device is also configured to identify an object.

公开(公告)号：US11998276B2

公开(公告)日：2024-06-04

申请号：US18053090

申请日：2022-11-07

Applicant: ZeaVision, LLC

Inventor： Scott J. Huter ,  Kevin Martin Magrini ,  Edward Allen DeHoog ,  Jeff Alan Burke ,  Nathan Franklin Engel

IPC: A61B3/12 ,  A61B3/00 ,  A61B3/10 ,  A61B3/14 ,  A61B3/15 ,  G01J3/02 ,  G01J3/42

CPC classification number: A61B3/12 ,  A61B3/0025 ,  A61B3/10 ,  A61B3/145 ,  A61B3/152 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/42 ,  G01J3/0218

Abstract: A reflectometry instrument includes a light source for emitting an illumination beam that illuminates the macula. A portion of the illumination beam is reflected from the macula and forms a detection beam. The detection beam is indicative of macular pigment in the macula. The instrument also includes a first mirror for reflecting the illumination beam toward the macula and for reflecting the detection beam from the macula. The instrument is configured so that the illumination beam and the detection beam remain separated between the macula and the first mirror.

公开(公告)号：US11986268B2

公开(公告)日：2024-05-21

申请号：US18139722

申请日：2023-04-26

Applicant: OHIO STATE INNOVATION FOUNDATION

Inventor： James Coe ,  Heather Allen ,  Charles Hitchcock ,  Edward W. Martin

IPC: A61B5/00 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/552 ,  A61B17/00 ,  A61B90/00

CPC classification number: A61B5/0075 ,  A61B5/444 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/552 ,  A61B2017/00061 ,  A61B2090/373 ,  A61B2505/05 ,  A61B2576/00 ,  G01J2003/425

Abstract: Disclosed are systems and methods utilizing an infrared probe and discriminating software to rapidly discriminate abnormal tissue processes from normal tissue during surgery, physical examination of in-situ lesions, and in the assessment of biopsy and resected tissue specimens. Examples demonstrate discrimination of cancerous from noncancerous tissues. The discriminating software, i.e. the metrics, algorithms, calibrant spectra, and decision equations, allows tissue to be identified as abnormal or normal using a minimum of infrared (IR) wavelengths in order to be measured rapidly. The probe records IR metrics approximately 1000 times faster than current commercial instruments, i.e. on a timescale fast enough for clinical use. The probe uses a tunable mid-infrared laser with a small set of selected wavelengths that are optimized for detecting the chemical and molecular signatures of tissue specific lesions to include, but not limited to, cancer, preneoplasia, intracellular accumulations (e.g. steatosis), inflammation, and wound healing.

公开(公告)号：US20240151700A1

公开(公告)日：2024-05-09

申请号：US18499763

申请日：2023-11-01

Applicant: REBELLION PHOTONICS, INC.

Inventor： Robert Timothy KESTER ,  Nathan Adrian HAGEN

IPC: G01N33/00 ,  G01J3/02 ,  G01J3/28 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J5/00 ,  G01J5/08 ,  G01J5/0806 ,  G01J5/0808 ,  G01J5/53 ,  G01J5/60 ,  G01N21/3504 ,  H04N5/33 ,  H04N17/00

CPC classification number: G01N33/0044 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0286 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J5/0014 ,  G01J5/0806 ,  G01J5/0808 ,  G01J5/0896 ,  G01J5/53 ,  G01J5/602 ,  G01N21/3504 ,  H04N5/33 ,  H04N17/002 ,  G01J2003/1247 ,  G01J2003/2826 ,  G01J2003/2869 ,  G01J2005/0077 ,  G01J2005/604 ,  G01N2021/3531

Abstract: Various embodiments disclosed herein describe an infrared (IR) imaging system for detecting a gas. The imaging system can include an optical filter that selectively passes light having a wavelength in a range of 1585 nm to 1595 nm while attenuating light at wavelengths above 1600 nm and below 1580 nm. The system can include an optical detector array sensitive to light having a wavelength of 1590 that is positioned rear of the optical filter.

公开(公告)号：US11967799B2

公开(公告)日：2024-04-23

申请号：US15508889

申请日：2015-08-28

Applicant: PILOT PHOTONICS LIMITED

Inventor： Jules Braddell ,  Frank Smyth

IPC: H01S5/065 ,  G01J3/10 ,  G01J3/42 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/39 ,  G01N21/45 ,  H01S5/00 ,  H01S5/042 ,  H01S5/10 ,  H01S5/40

CPC classification number: H01S5/0656 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3504 ,  H01S5/0064 ,  H01S5/0085 ,  H01S5/0427 ,  H01S5/1096 ,  H01S5/4006 ,  G01N2021/3133 ,  G01N2021/3148 ,  G01N2021/399 ,  G01N2021/451 ,  G01N2201/0612

Abstract: A method of performing spectroscopic measurements provides an optical frequency comb, and directs the comb through or at a sample. The optical frequency comb is generated by gain switching a laser diode constructed from Gallium Nitride and related materials. Various techniques are described for manipulating the comb source to achieve desired benefits for spectroscopy.

公开(公告)号：US20240110832A1

公开(公告)日：2024-04-04

申请号：US18276300

申请日：2022-02-07

Applicant: Trustees of Tufts College

Inventor： Sergio Fantini ,  Giles Blaney ,  Angelo Sassaroli

IPC: G01J3/42 ,  G01N21/03 ,  G01N21/31 ,  G01N21/51

CPC classification number: G01J3/42 ,  G01N21/0303 ,  G01N21/3103 ,  G01N21/51

Abstract: A self-calibrating hybrid spectrophotometer comprises a receptacle for receiving the cuvette, first and second optodes that are configured to permit light to enter the cuvette, third and fourth optodes that are configured to permit light to leave the cuvette, and a controller that is configured to control delivery of light to one of the first and second optodes. Light entering one of the first and second optodes is received at the third and fourth optodes after having interacted with the turbid sample along different paths having different lengths. Measurements made at the third and fourth optodes in response to having illuminated both the first and second source optodes provide two slopes of optical transmittance as a function of path length. The spectrophotometer uses these slopes to identify a slope that is indicative of the absorption coefficient and the reduced scattering coefficient of the sample.

公开(公告)号：US20240094118A1

公开(公告)日：2024-03-21

申请号：US18471124

申请日：2023-09-20

Applicant: Rebellion Photonics, Inc.

Inventor： Robert Timothy Kester ,  Nathan Adrian Hagen ,  Ryan Mallery

IPC: G01N21/3504 ,  G01J3/28 ,  G01J3/42 ,  G01M3/26 ,  G01M3/38

CPC classification number: G01N21/3504 ,  G01J3/2823 ,  G01J3/42 ,  G01M3/26 ,  G01M3/38 ,  G01N2021/1793

Abstract: An instrument and method for analyzing a gas leak. The instrument can obtain a time series of spectra from a scene. The instrument can compare spectra from different times to determine a property of a gas cloud within the scene. The instrument can estimate the column density of the gas cloud at one or more locations within the scene. The instrument can estimate the total quantity of gas in the cloud. The instrument can estimate the amount of gas which has left the field of view of the instrument. The instrument can also estimate the amount of gas in the cloud which has dropped below the sensitivity limit of the instrument.

公开(公告)号：US11933732B2

公开(公告)日：2024-03-19

申请号：US17471139

申请日：2021-09-09

Applicant: UNM Rainforest Innovations

Inventor： Mani Hossein-Zadeh

IPC: G01N1/00 ,  G01J3/02 ,  G01J3/42 ,  G01J3/453 ,  G01N21/77 ,  G01N33/543 ,  G02B6/122 ,  G02B6/125

CPC classification number: G01N21/7703 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/42 ,  G01J3/453 ,  G01N33/54373 ,  G02B6/1223 ,  G02B6/1225 ,  G02B6/125 ,  G01N2201/0638

Abstract: The present invention provides a sensor having, one or more optical slab waveguides having one or more target regions. The target regions may interact with gas molecules or trap, entrain or capture one or more targets of interest. The optical slab waveguides are adapted to receive one or more input optical beams from one or more light sources to create a plurality of propagating optical waves in optical slab waveguide. The propagating optical waves interact with said one or more target regions to create an optical output wavefront that may be in the form of a diffraction pattern. The target regions may be functionalized with an antibody, polymer, cell, tissue, or biological material.

公开(公告)号：US20240068868A1

公开(公告)日：2024-02-29

申请号：US18505253

申请日：2023-11-09

Applicant: VIAVI Solutions Inc.

Inventor： William D. HOUCK ,  Valton SMITH

IPC: G01J3/02 ,  G01J3/42 ,  G01S17/08

CPC classification number: G01J3/027 ,  G01J3/0229 ,  G01J3/42 ,  G01S17/08

Abstract: A device may determine a time-of-flight measurement by performing a sample of a sensor based on light received via at least one first spectral filter, wherein the at least one first spectral filter is associated with a spectral range for a time-of-flight measurement; determine that a condition is satisfied with regard to the time-of-flight measurement, wherein the condition relates to an orientation or a position of the sensor or the sensor device relative to a measurement target; trigger a spectrometry measurement to be performed based on determining that the condition is satisfied with regard to the time-of-flight measurement; and perform, based on light received via at least one second spectral filter and by performing a sample of the sensor, the spectrometry measurement for the measurement target based on the condition being satisfied with regard to the time-of-flight measurement.