Apparatus and method for measuring spectral property of fluorescent sample
    11.
    发明授权
    Apparatus and method for measuring spectral property of fluorescent sample 有权
    用于测量荧光样品的光谱性质的装置和方法

    公开(公告)号:US06535278B1

    公开(公告)日:2003-03-18

    申请号:US09500481

    申请日:2000-02-09

    Applicant: Kenji Imura

    Inventor: Kenji Imura

    CPC classification number: G01N21/276 G01J3/44 G01J2003/2866 G01N21/645

    Abstract: In an apparatus for measuring a spectral property such as a total spectral radiant factor of a fluorescent sample, a weight factor is previously calculated by using a standard fluorescent sample in which an index of a spectral property such as a total spectral radiant factor is known. When a spectral intensity distribution of a fluorescent sample to be measured is measured, the measured spectral intensity distribution is corrected similar to a value when the fluorescent sample is illuminated as if the same illumination light when the weight factor is set. As a result, the error component in the measurement result due to the variation of the illumination light in a time period from the setting of the weight factor to the measurement of the fluorescent sample can be reduced.

    Abstract translation: 在用于测量诸如荧光样品的总光谱辐射因子之类的光谱特性的装置中,通过使用其中诸如总光谱辐射系数的光谱特性的指数已知的标准荧光样品,预先计算加权因子。 当测量要测量的荧光样品的光谱强度分布时,测量的光谱强度分布类似于当荧光样品被照亮时的值被校正,就像在设定重量因子时相同的照明光一样。 结果,可以减少在从重量因数的设定到荧光试样的测量的时间段内的照明光的变化引起的测量结果中的误差分量。

    Multipoint wavelength calibration technique
    12.
    发明授权
    Multipoint wavelength calibration technique 失效
    多点波长校准技术

    公开(公告)号:US06362878B1

    公开(公告)日:2002-03-26

    申请号:US09430338

    申请日:1999-10-29

    CPC classification number: G01J3/28 G01J2003/2866

    Abstract: Improved calibration of optical wavelength measuring instruments. In a first embodiment, improved calibration is achieved in an optical wavelength measuring instrument by performing calibration measurements at a plurality of known wavelengths and using an average calibration constant derived from the plurality of measurements. In a second embodiment, improved calibration is achieved by performing calibration measurements at a plurality of known wavelengths and calculating a linear or higher order calibration model, or a periodic model. These approaches may be extended by segmenting the wavelength range and using different calculated calibration values, or different calibration models, for each segment.

    Abstract translation: 改进光学波长测量仪器的校准。 在第一实施例中,通过在多个已知波长下执行校准测量并使用从多个测量导出的平均校准常数,在光学波长测量仪器中实现了改进的校准。 在第二实施例中,通过以多个已知波长执行校准测量并计算线性或更高阶校准模型或周期性模型来实现改进的校准。 这些方法可以通过分段波长范围和使用不同计算的校准值或不同的校准模型来扩展。

    Methods and apparatus for improving the long-term stability of spectroscopic quantitative analyses
    13.
    发明授权
    Methods and apparatus for improving the long-term stability of spectroscopic quantitative analyses 有权
    提高光谱定量分析的长期稳定性的方法和装置

    公开(公告)号:US06674526B1

    公开(公告)日:2004-01-06

    申请号:US09919820

    申请日:2001-08-02

    Applicant: Ralf Marbach

    Inventor: Ralf Marbach

    CPC classification number: G01J3/2803 G01J3/0297

    Abstract: The long-term stability of the analytic accuracy of spectroscopic measurements is often limited by wavelength axis instabilities of the hardware. A dedicated optical element called the inverse sample element (4) is inserted into the path of the measurement light. The optical response of the inverse sample element (4) is determined from the spectral response of the average sample (3) in such a way that wavelength axis instabilities of the instrument hardware cause opposite and nearly cancelled amplitude effects in the resulting absorbance spectrum. The inverse sample element (4) can be movable or permanently mounted inside the instrument and is preferably made from a thin-film structure.

    Abstract translation: 光谱测量的分析精度的长期稳定性常常受到硬件波长轴不稳定性的限制。 称为反样本元件(4)的专用光学元件插入到测量光的路径中。 反样本元素(4)的光学响应由平均样品(3)的光谱响应确定,使得仪器硬件的波长轴不稳定性在所得吸收光谱中引起相反且几乎取消幅度效应。 反样本元件(4)可以可移动或永久地安装在仪器内部,并且优选地由薄膜结构制成。

    Process and apparatus for measuring density fluctuations occurring with pulsed irradiation of a material
    14.
    发明授权
    Process and apparatus for measuring density fluctuations occurring with pulsed irradiation of a material 有权
    用于测量材料脉冲照射时发生的密度波动的方法和装置

    公开(公告)号:US06671043B1

    公开(公告)日:2003-12-30

    申请号:US09614701

    申请日:2000-07-12

    Inventor: Gereon Huettman

    Abstract: A process and an apparatus preferably used during the photocagulation of the fundus of human eyes or animals measures density fluctuations caused by pulsed irradiation, such as a laser irradiation source, on a material. A wherein a measuring signal is acoustically or optically detected. The change of the intensity and/or of the time slope of the measuring signal resulting from the irradiation of a specific material point is detected. A linear thermo-elastic signal fraction is removed from the measuring signal.

    Abstract translation: 优选在人眼或动物的眼底的光凝中使用的方法和装置测量由诸如激光照射源的脉冲照射引起的材料上的密度波动。 A,其中测量信号是声学或光学检测的。 检测由特定材料点的照射产生的测量信号的强度和/或时间斜率的变化。 从测量信号中去除线性热弹性信号分数。

    SNR calculation method and optical spectrum measurement apparatus
    15.
    发明授权
    SNR calculation method and optical spectrum measurement apparatus 失效
    SNR计算方法和光谱测量装置

    公开(公告)号:US06643011B2

    公开(公告)日:2003-11-04

    申请号:US10080820

    申请日:2002-02-21

    Applicant: Manabu Kojima

    Inventor: Manabu Kojima

    CPC classification number: G01J3/02 G01J3/027 G01J3/28

    Abstract: An SNR calculation method having the steps of measuring the wavelength characteristic of a dynamic range in an optical spectrum measurement apparatus for each wavelength in a multiplexed wavelength range and storing the wavelength characteristic in a storage unit, measuring the signal level and the noise level of a measured optical signal wavelength, reading the noise level of the wavelength of the measured optical signal produced by each of other optical signal wavelengths multiplexed on the measured optical signal wavelength from the storage unit, subtracting the noise level read from the storage unit from the noise level of the measured optical signal wavelength to provide the corrected noise level, and calculating the SNR of the measured optical signal from the measured optical signal level and the corrected noise level.

    Abstract translation: 一种SNR计算方法,具有以下步骤:在多个波长范围内测量光谱测量装置中每个波长的动态范围的波长特性,并将波长特性存储在存储单元中,测量信号电平和噪声电平 测量光信号波长,从存储单元读取在测量的光信号波长上复用的其他光信号波长中的每一个产生的测量光信号的波长的噪声电平,从存储单元读取的噪声电平从噪声电平 的测量光信号波长以提供校正的噪声电平,以及根据测量的光信号电平和校正的噪声电平计算测量的光信号的SNR。

    Multispectral imaging system for contaminant detection

    公开(公告)号:US06639665B2

    公开(公告)日:2003-10-28

    申请号:US09779706

    申请日:2001-02-09

    Applicant: Gavin H. Poole

    Inventor: Gavin H. Poole

    CPC classification number: G01N21/31 G01N21/94

    Abstract: An automated inspection system for detecting digestive contaminants on food items as they are being processed for consumption includes a conveyor for transporting the food items, a light sealed enclosure which surrounds a portion of the conveyor, with a light source and a multispectral or hyperspectral digital imaging camera disposed within the enclosure. Operation of the conveyor, light source and camera are controlled by a central computer unit. Light reflected by the food items within the enclosure is detected in predetermined wavelength bands, and detected intensity values are analyzed to detect the presence of digestive contamination.

    Real time process control of optical components using linearly swept tunable laser
    17.
    发明授权
    Real time process control of optical components using linearly swept tunable laser 有权
    使用线性扫描可调谐激光器对光学元件的实时过程控制

    公开(公告)号:US06597449B1

    公开(公告)日:2003-07-22

    申请号:US09494614

    申请日:2000-01-31

    CPC classification number: G01M11/33 G01M11/00

    Abstract: A system and method for real time process control, using a linearly swept tunable laser, which allows high speed in-situ monitoring and control of wavelength-specific properties of optical components. The invention comprises scanning an optical component with a high speed, high linearity tunable laser, and detecting optical output from the component during the scanning. Preferably, the invention also includes adjusting or controlling the optical properties of the component during scanning, according to detected optical output from the component. The invention is embodied in a process control system comprising a high speed, high linearity, tunable operatively coupled to an optical component which in turn is operatively coupled to an optical detector. A system control processor is operatively coupled to the tunable laser and detector. A processing control unit is associated with the optical component and is operatively coupled to the system control processor. In operation, the optical component is scanned by the tunable laser, and real time process control of one or more wavelength specific properties of the optical component may be carried out according to feedback from the optical detector and process control unit.

    Abstract translation: 一种用于实时过程控制的系统和方法,使用线性扫描可调谐激光器,其允许高速原位监测和控制光学部件的波长特性。 本发明包括用高速,高线性可调谐激光器扫描光学部件,以及在扫描期间检测来自部件的光学输出。 优选地,本发明还包括根据检测到的来自组件的光学输出来调整或控制扫描期间部件的光学特性。 本发明体现在一种过程控制系统中,该系统包括可操作地耦合到光学部件的高速度,高线性度的可调谐的光学部件,光学部件又可操作地耦合到光学检测器。 系统控制处理器可操作地耦合到可调谐激光器和检测器。 处理控制单元与光学部件相关联并且可操作地耦合到系统控制处理器。 在操作中,光学部件被可调激光器扫描,并且可以根据来自光学检测器和过程控制单元的反馈来执行光学部件的一个或多个波长特定属性的实时处理控制。

    Infrared spectroscopy for medical imaging
    18.
    发明授权
    Infrared spectroscopy for medical imaging 失效
    红外光谱学用于医学成像

    公开(公告)号:US06181414B2

    公开(公告)日:2001-01-30

    申请号:US09368521

    申请日:1999-08-05

    Abstract: A multi-channel spectral imaging module for an automated testing system for cytological applications. The multi-channel spetral imaging module generates four channels of digitized images of a cytological specimen for further processing in the automated testing system. The multi-spectral imaging module comprises a visible light source and an infrared light source, an optical imaging module, a prism module, and an output stage. The cytological specimen is strobed by the visible light and infrared light sources and the illuminated images of the specimen are focussed and coupled to the prism module by the optical imaging module. The prism module breaks the illuminated image into four channels comprising three visible light channels and an infrared channel. The output stage comprises a CCD array sensor for each channel. The CCD array sensor digitizes the image for channel and produces an output for further processing. The digitized output from the infrared channel provides additional information which is used by the automated testing system. The additional information derived from the infrared channel includes segmentation information, new identifying features for the specimen, and discrimination measures independent of the visible light channels. In another embodiment, a fifth channel is provided for a reference infrared output and the two infrared channels are operated in a differential mode.

    Abstract translation: 用于细胞学应用的自动化测试系统的多通道光谱成像模块。 多通道spetral成像模块生成四个通道的细胞学标本的数字化图像,用于在自动化测试系统中进一步处理。 多光谱成像模块包括可见光源和红外光源,光学成像模块,棱镜模块和输出级。 细胞学样本被可见光和红外光源选通,并且通过光学成像模块将样本的照射图像聚焦并耦合到棱镜模块。 棱镜模块将照明图像分成四个通道,包括三个可见光通道和一个红外通道。 输出级包括用于每个通道的CCD阵列传感器。 CCD阵列传感器将通道图像数字化,并产生一个输出进一步处理。 红外通道的数字化输出提供了自动测试系统使用的附加信息。 从红外线通道导出的附加信息包括分割信息,样本的新识别特征以及独立于可见光通道的鉴别度量。 在另一个实施例中,为参考红外输出提供第五通道,并且两个红外通道以差分模式操作。

    Field based spectral radiometer
    19.
    发明授权
    Field based spectral radiometer 失效
    基于场的光谱辐射计

    公开(公告)号:US06713764B2

    公开(公告)日:2004-03-30

    申请号:US10073323

    申请日:2002-02-13

    Abstract: A robust two spectral band radiometer for long-term stand-alone spectral radiance measurements in the field is provided. The instrument can be used to monitor various surface parameters over prolonged periods of time by automatically collecting spectral radiance measurements at a user selected time interval (minutes to days). Two main applications are the monitoring of water surface parameters, such as total SSC and turbidity, and on-land vegetation by collecting spectral radiance measurements in a broad visible red and near-infrared spectral bands. Use for other application is possible using different spectral bands and multiple radiometers. Also included is the use of a ratioing technique to correlate the spectral radiance values rather than spectral reflectance values to the surface parameters of interest; this simplifies both the filed instrumentation requirements and post processing procedures.

    Abstract translation: 提供了一个用于长期独立光谱辐射测量的强大的两个光谱带辐射计。 仪器可以通过在用户选择的时间间隔(分钟到天)自动收集光谱辐射度测量值,在长时间内监测各种表面参数。 两个主要应用是通过在广泛的可见红色和近红外光谱带中收集光谱辐射测量来监测水面参数,如总SSC和浊度,以及陆上植被。 使用不同的光谱带和多个辐射计可以用于其他应用。 还包括使用比例技术来将光谱辐射度值而不是光谱反射率值与感兴趣的表面参数相关联; 这简化了现有的仪器要求和后处理程序。

    System and method for optical spectrum fast peak reporting

    公开(公告)号:US06639666B2

    公开(公告)日:2003-10-28

    申请号:US10005712

    申请日:2001-11-08

    Applicant: Yu Li

    Inventor: Yu Li

    CPC classification number: G01J3/26 G01J3/02 G01J3/0264 G01J3/28

    Abstract: A system and method for fast peak finding in an optical spectrum prioritizes the information it first generates and how the information is then forwarded from the system to a host computer, for example. A spectrum detection subsystem generates a spectrum of an optical signal. An analog-to-digital converter converts the spectrum into sample data. Finally, a data processing subsystem first detects the spectral locations of peaks in the spectrum using the sample data and then uploads the peak information to a host computer before performing processing to determine the shapes of the peaks and/or noise information for the optical signal, for example. The system is thus able to quickly find some information, such as whether or not channels or carriers are present, at what frequency the carriers are operating, and the carriers' power level, and send this information to the host computer. In contrast, information concerning spectral shape or the noise floor is sent later in time.

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