公开(公告)号：US10670458B2

公开(公告)日：2020-06-02

申请号：US16091837

申请日：2017-04-03

Applicant: HORIBA FRANCE SAS

Inventor： Simon Richard ,  Sébastien Laden ,  Dmitri Kouznetsov

IPC: G01J3/28 ,  G01J3/44 ,  G01N21/64 ,  G01N21/65 ,  G06T3/40 ,  G01J3/02

Abstract: Disclosed is a method for acquiring and forming a spectrometry image, including the following steps: a) acquiring an initial structural image of an area of a sample; b) breaking down the initial structural image so as to determine a multi-scale spatial sample of the area of the sample; c) determining a plurality of spectrometry measurement positions in the area of the sample, as a function of the multi-scale spatial sampling determined in step b); d) consecutively, for each spectrometry measurement position determined in step c), positioning the excitation beam and acquiring a spectrometry measurement; and e) reconstructing a spectrometry image point-by-point from the spectrometry measurements acquired in step d).

公开(公告)号：US10663405B2

公开(公告)日：2020-05-26

申请号：US16281432

申请日：2019-02-21

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Woochang Lee ,  Ho Jun Chang

IPC: G01N21/65 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/02 ,  G01J3/44

Abstract: Provided are a Raman probe and a bio-component analyzing apparatus using the same. The Raman probe according to an embodiment of the present disclosure may include: a probe head having a concave part configured to receive skin of an object being inserted into the concave part when the probe head comes into contact with the skin of the object; a light source part configured to emit light onto the skin inserted into the concave part; and a light collector formed above the concave part and configured to collect Raman scattered light from the skin inserted into the concave part. The light source part may be disposed on a side of at least one of the light collector and the concave part.

公开(公告)号：US10653355B2

公开(公告)日：2020-05-19

申请号：US15545488

申请日：2016-02-05

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Hequn Wang ,  Conor L. Evans ,  Sam Osseiran ,  David E. Fisher

IPC: A61B5/00 ,  G01J3/44 ,  G01N21/88 ,  G01N21/17 ,  G01N21/41 ,  G01N21/65

Abstract: A system for visualizing melanin present in tissue can include an imaging system to record a signal based on a presence of melanin in tissue and a display device to display an image based on the signal. A first laser source can emit a Stokes pulse train and a second laser source can emit a pump pulse train. Both the first laser source and the second laser source comprise a tunable center wavelength or frequency. An energy difference between a frequency of the Stokes pulse train and a frequency of the pump pulse train is from 1750 cm−1 to 2250 cm−1. The Stokes and the pump pulse train overlap in space and time. A scanning mechanism focuses the combined Stokes pulse train and pump pulse train within the tissue and scans across the tissue. A detector detects the signal based on a presence of melanin within the tissue.

公开(公告)号：US10648915B2

公开(公告)日：2020-05-12

申请号：US15764327

申请日：2015-11-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ning Ge ,  Steven Barcelo ,  Anita Rogacs ,  Helen A Holder

IPC: G01N21/65 ,  G01N21/64 ,  G01J3/44 ,  B65B31/06 ,  B81C1/00

Abstract: In an example implementation, a substance detection device includes a chamber with chamber walls, a chamber top, and a chamber bottom. A substrate comprises imprinted nanostructures positioned within the chamber, and the substrate is coupled to the chamber walls to form the chamber bottom. An inert gas is sealed within the chamber.

公开(公告)号：US10608400B2

公开(公告)日：2020-03-31

申请号：US14350062

申请日：2012-10-04

Applicant: Cornell University

Inventor： Frank Wise ,  Simon Lefrancois

IPC: H01S3/108 ,  G02F1/35 ,  G02F1/39 ,  G01J3/10 ,  G01J3/44 ,  H01S3/23 ,  H01S3/00 ,  G01N21/65

Abstract: Devices and techniques that use nonlinear optical effects in optical fiber to generate optical pulses via nonlinear optical wave mixing for various applications such as coherent Raman microscopic measurements and optical parametric oscillators. In some implementations, a tunable optical delay path is provided to cause an adjustable delay for synchronizing two optical beams of optical pulses.

公开(公告)号：US10605702B2

公开(公告)日：2020-03-31

申请号：US16000616

申请日：2018-06-05

Applicant: VIRTUAL FLUID MONITORING SERVICES LLC

Inventor： Dustin Young ,  Mark Chmielewski ,  Chris Morton ,  Michael Siers

IPC: G01N1/10 ,  G01N33/28 ,  F01M11/10 ,  G06F17/14 ,  G01N35/00 ,  G01N21/31 ,  G01N21/64 ,  G01N15/06 ,  G01N21/85 ,  G06N5/00 ,  G06N20/10 ,  G01J3/44 ,  G01N15/14 ,  G01N21/65 ,  G06N3/08 ,  G01N21/94 ,  G01N15/00 ,  G01N21/84 ,  G01N21/3577 ,  G01N21/35

Abstract: Systems, methods, and computer-program products for fluid analysis and monitoring are disclosed. Embodiments include a removable and replaceable sampling system and an analytical system connected to the sampling system. A fluid may be routed through the sampling system and data may be collected from the fluid via the sampling system. The sampling system may process and transmit the data to the analytical system. The analytical system may include a command and control system to receive and store the data in a database and compare the data to existing data for the fluid in the database to identify conditions in the fluid. Fluid conditions may be determined using machine learning models that are generated from well-characterized known training data. Predicted fluid conditions may then be used to automatically implement control processes for an operating machine containing the fluid.

公开(公告)号：US20200088645A1

公开(公告)日：2020-03-19

申请号：US16473192

申请日：2018-02-13

Applicant: Nuctech Company Limited

Inventor： Jianhong Zhang ,  Hongqiu Wang ,  Rui Fan ,  Haihui Liu

IPC: G01N21/65 ,  G01J3/44

Abstract: There are provided a Raman spectrum inspection apparatus (100a) and a method of monitoring detection security of the same. The Raman spectrum inspection apparatus (100a) includes: an optical device (20) configured to guide exciting light (11) to a sample (30) and collect a light signal from the sample (30); a spectrometer (40) configured to split the light signal collected by the optical device (20) so as to generate a Raman spectrum of the sample (30) which is detected; and a security monitor configured to monitor a security state of the sample (30) during irradiating of the exciting light (11) from the laser (10) onto the sample (30), and to provide a security indicating signal representing whether or not the sample (30) is damaged due to being irradiated by the exciting light (11).

公开(公告)号：US10591388B2

公开(公告)日：2020-03-17

申请号：US15997612

申请日：2018-06-04

Applicant: VIRTUAL FLUID MONITORING SERVICES LLC

Inventor： Dustin Young ,  Mark Chmielewski ,  Chris Morton ,  Michael Siers ,  Scott Rudder

IPC: G01N1/10 ,  G01N33/28 ,  F01M11/10 ,  G06F17/14 ,  G01N35/00 ,  G01N21/31 ,  G01N21/64 ,  G01N15/06 ,  G01N21/85 ,  G06N5/00 ,  G06N20/10 ,  G01J3/44 ,  G01N15/14 ,  G01N21/65 ,  G06N3/08 ,  G01N21/94 ,  G01N15/00 ,  G01N21/84 ,  G01N21/3577 ,  G01N21/35

Abstract: Systems, methods, and computer-program products for fluid analysis and monitoring are disclosed. Embodiments include a removable and replaceable sampling system and an analytical system connected to the sampling system. A fluid may be routed through the sampling system and data may be collected from the fluid via the sampling system. The sampling system may process and transmit the data to the analytical system. The analytical system may include a command and control system to receive and store the data in a database and compare the data to existing data for the fluid in the database to identify conditions in the fluid. Fluid conditions may be determined using machine learning models that are generated from well-characterized known training data. Predicted fluid conditions may then be used to automatically implement control processes for an operating machine containing the fluid.

公开(公告)号：US20200064248A1

公开(公告)日：2020-02-27

申请号：US16530524

申请日：2019-08-02

Applicant: VIAVI Solutions Inc.

Inventor： William D. HOUCK

IPC: G01N15/02 ,  G01J3/44 ,  G01N21/53 ,  G01N33/00 ,  G08B17/107

Abstract: An optical detector device may receive a spectroscopic measurement from a multispectral sensor. The optical detector device may determine, based on the spectroscopic measurement, a particulate size of a particulate. The optical detector device may determine, based on the spectroscopic measurement, an identification of the particulate. The optical detector device may determine, based on the particulate size and the identification of the particulate, that an alert condition is satisfied. The optical detector device may trigger an alert based on determining that the alert condition is satisfied.

公开(公告)号：US20200057011A1

公开(公告)日：2020-02-20

申请号：US16533291

申请日：2019-08-06

Applicant: FEI Company

Inventor： Tomas Tuma ,  Jan Hradil ,  Petr Hlavenka

IPC: G01N23/2252 ,  H01J37/28 ,  G01J3/44

Abstract: The disclosure relates to a method of examining a sample using a charged particle microscope. The method comprises the steps of detecting using a first detector emissions of a first type from the sample in response to the beam scanned over the area of the sample. Then, using spectral information of detected emissions of the first type, at least a part of the scanned area of the sample is divided into multiple segments. According to the disclosure, emissions of the first type at different positions along the scan in at least one of said multiple segments may be combined to produce a combined spectrum of the sample in said one of said multiple segments. In an embodiment, a second detector is used to detect emissions of a second type, and this is used to divide the area of the sample into multiple regions. The first detector may be an EDS, and the second detector may be based on EM. This way, EDS data and EM data can be effectively combined for producing colored images.