公开(公告)号：US08796618B2

公开(公告)日：2014-08-05

申请号：US13511157

申请日：2010-11-16

Applicant: Seung Yong Kim ,  Hyun Sik Kim ,  Jong Shin Yoo

Inventor： Seung Yong Kim ,  Hyun Sik Kim ,  Jong Shin Yoo

IPC: H01J49/38 ,  H01J49/02

CPC classification number: H01J49/38 ,  H01J49/022

Abstract: The present invention relates to an apparatus and method for controlling a pipeline-type ion cyclotron resonance mass spectrometer, in which an ion trap unit of the ion cyclotron resonance mass spectrometer is capable of using two digitizers at the same time, thus enabling a measurement process for detecting an electrical signal which indicates the mass of ions corresponding to a specific purpose, and another measurement process for detecting another electrical signal which indicates the mass of ions corresponding to another specific purpose, to be simultaneously performed. Accordingly, it is an aim of the present invention to provide an apparatus and method for controlling a pipeline-type ion cyclotron resonance mass spectrometer, which can overcome the problems of time delay among control procedures, and can present a signal detection step wherein an excitation electrode is utilized to improve the sensitivity and speed of signal detection.

Abstract translation: 本发明涉及一种用于控制管道型离子回旋共振质谱仪的装置和方法，其中离子回旋共振质谱仪的离子阱单元能够同时使用两个数字化仪，因此能够进行测量过程 用于检测指示对应于特定目的的离子质量的电信号，以及用于检测指示与另一特定目的相对应的离子质量的另一电信号的另一测量处理。 因此，本发明的目的是提供一种用于控制管道型离子回旋共振质谱仪的装置和方法，其可以克服控制过程之间的时间延迟的问题，并且可以呈现信号检测步骤，其中激发 电极用于提高信号检测的灵敏度和速度。

公开(公告)号：US20140180625A1

公开(公告)日：2014-06-26

申请号：US13869868

申请日：2013-04-24

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Yeon Suk Choi ,  Dong Lak Kim

IPC: G06F17/50

CPC classification number: G06F17/5009 ,  G01K7/425 ,  G06F1/20 ,  G06F1/206

Abstract: The present invention provides a system and method of predicting the initial cooling of a superconducting magnet, which can predict the change in initial cooling temperature of a superconducting magnet when the superconducting magnet is cooled using an ultra-low refrigerator. In the system and method, the change in cooling temperature of a superconducting magnet can be accurately predicted by classifying influence factors related to the cooling of a superconducting magnet into a plurality of control volumes and inducing a governing equation with respect to each of the control volumes. Based on this system and method, the reliability of basic data required to design an apparatus for measuring a high magnetic field for forming an ultralow-temperature environment can be greatly improved.

Abstract translation: 本发明提供一种预测超导磁体的初始冷却的系统和方法，该超导磁体可以预测超导磁体使用超低温冷藏器冷却时超导磁体的初始冷却温度的变化。 在该系统和方法中，可以通过将与超导磁体的冷却相关的影响因素分类为多个控制体积并且针对每个控制体积引导控制方程，可以准确地预测超导磁体的冷却温度的变化 。 基于该系统和方法，可以大大提高设计用于测量用于形成超低温环境的高磁场的装置所需的基本数据的可靠性。

公开(公告)号：US08723112B2

公开(公告)日：2014-05-13

申请号：US13699577

申请日：2011-10-31

Applicant: Seung Yong Kim ,  Hyun Sik Kim ,  Myoung Choul Choi ,  Jong Shin Yoo

Inventor： Seung Yong Kim ,  Hyun Sik Kim ,  Myoung Choul Choi ,  Jong Shin Yoo

IPC: H01J49/02

CPC classification number: H01J49/02 ,  H01J49/022 ,  H01J49/38

Abstract: Provided are a controller and a control method for improving signal performance of an ion cyclotron resonance mass spectrometer. The controller and control method apply electric signals for causing ions injected into an ion trap of the ion cyclotron resonance mass spectrometer to be injected to the center of the trap as close as possible to trap electrodes, and adjust biased ion motion by appropriately adjusting signals of trap electrodes for causing the injected ions to make ion motion, thereby improving the fidelity of ion signals. The control method for improving signal performance of an ion cyclotron resonance mass spectrometer includes an ion position adjustment process and an ion signal detection process.

Abstract translation: 提供了一种用于改善离子回旋共振质谱仪的信号性能的控制器和控制方法。 控制器和控制方法应用电信号，使离子回旋共振质谱仪的离子阱中注入的离子尽可能的靠近陷阱的中心捕获电极，并通过适当调整信号 用于引起注入的离子离子运动的捕获电极，从而提高离子信号的保真度。 用于提高离子回旋共振质谱仪的信号性能的控制方法包括离子位置调整处理和离子信号检测处理。

公开(公告)号：US08700135B2

公开(公告)日：2014-04-15

申请号：US13708329

申请日：2012-12-07

Applicant: Korea Basic Science Institute

Inventor： Ki Soo Chang ,  Seon Young Ryu ,  Sun Cheol Yang ,  Geon Hee Kim ,  Hae Young Choi

IPC: A61B6/00

CPC classification number: A61B1/07 ,  A61B1/00096 ,  A61B1/0011 ,  A61B1/00167 ,  A61B5/0071

Abstract: Provided is an imaging system which includes an optical fiber array probe unit integrated with an endoscope unit, thereby simultaneously measuring structural information and functional information of a sample. The optical fiber array probe unit includes an optical fiber array probe integrated with lenses including an optical fiber lens with a lens surface of a predetermined radius of curvature in which one ends of optical fibers are integrally connected with each other by heating a predetermined region including the one ends of two of the optical fibers using a heating means, as an optical fiber array probe integrated lens on which the light transmitted from the light source is incident and which guides light reflected from the sample, and a detector for selectively detecting the light transmitted from the optical fiber array probe integrated with lenses in a predetermined range of wavelength.

Abstract translation: 提供了一种成像系统，其包括与内窥镜单元集成的光纤阵列探针单元，从而同时测量样品的结构信息和功能信息。 光纤阵列探针单元包括与透镜组合的光纤阵列探针，该透镜包括具有预定曲率半径的透镜表面的光纤透镜，其中光纤的一端通过加热包括 使用加热装置的两根光纤的一端作为光纤阵列探针集成透镜，其中从光源透射的光入射到该光纤阵列探针集成透镜，并且其引导从样品反射的光;以及检测器，用于选择性地检测透射的光 从与预定波长范围的透镜集成的光纤阵列探针。

公开(公告)号：US20140042579A1

公开(公告)日：2014-02-13

申请号：US14056915

申请日：2013-10-17

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Ki Soo Chang ,  Geon Hee Kim ,  Sun Cheol Yang ,  Hyo Sik Kim

IPC: H01L31/0232 ,  H01L31/18

CPC classification number: H01L31/0232 ,  B29D11/00365 ,  B29D11/00807 ,  H01L27/14627 ,  H01L27/14685 ,  H01L31/02327 ,  H01L31/18

Abstract: The present invention relates to an image sensor comprising a microlens array, and to a manufacturing method thereof. The method of the present invention includes gradually increasing the aluminum composition ratio of a compound semiconductor as the latter gradually gets farther from a substrate, to enable a microlens-forming layer to grow, and making the oxidation rate of the region adjacent to the substrate slower and the oxidation rate of the region farther from the substrate faster, making the interface between the oxidized region and the unoxidized region into a lens shape after the completion of oxidation. The thus-made lens is integrated into an image sensor. The present invention reduces costs for manufacturing image sensors in which a microlens is integrated, increases the signal-to-noise ratio and resolution of the image sensor, and achieves improved sensitivity.

Abstract translation: 本发明涉及一种包括微透镜阵列的图像传感器及其制造方法。 本发明的方法包括逐渐增加化合物半导体的铝组成比，随着后者从衬底逐渐变得越远，以使微透镜形成层生长，并且使与邻近衬底的区域的氧化速率变慢 并且距离衬底更远的区域的氧化速率更快，使氧化区域和未氧化区域之间的界面在氧化完成后成为透镜形状。 这样制成的镜头被集成到图像传感器中。 本发明降低了其中集成微透镜的图像传感器的制造成本，增加了图像传感器的信噪比和分辨率，并且实现了改进的灵敏度。

公开(公告)号：US20130315839A1

公开(公告)日：2013-11-28

申请号：US13956245

申请日：2013-07-31

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Chulhyun LEE ,  Sung Lan JEON ,  Min Kyung CHAE ,  Jee-Hyun CHO ,  Eun Ju JANG

IPC: A61B5/055 ,  A61K9/51

CPC classification number: A61B5/055 ,  A61K9/51 ,  A61K9/5115 ,  A61K49/1836 ,  A61K49/186 ,  A61K49/1863 ,  B82Y5/00 ,  B82Y15/00 ,  B82Y30/00 ,  C01G49/04 ,  C01G49/08 ,  C01P2002/72 ,  C01P2004/04 ,  C01P2004/34 ,  C01P2004/64 ,  C09C1/24 ,  Y10S977/773 ,  Y10S977/788 ,  Y10S977/81 ,  Y10S977/906 ,  Y10S977/93

Abstract: Iron oxide nano contrast agents for Magnetic Resonance Imaging which have superior T2 contrast effect, and also can be used as a storage or a carrier for drugs and so on, are disclosed. The iron oxide nano contrast agents can be prepared by the steps of: coating surfaces of hydrophobic FeO nanoparticles with a coating material selected from the group consisting of polyethylene glycol-phospholipid conjugate, dextran, chitosan, dimercaptosuccinic acid and mixtures thereof in an organic solvent to form hydrophilic FeO nanoparticles having hydrophilic surfaces and dispersibility in water; dispersing the hydrophilic FeO nanoparticles in water to oxidize FeO; and exposing the oxidized hydrophilic FeO nanoparticles to an acidic buffer to dissolve and remove interior unoxidized FeO portions, and thereby to form Fe3O4 nanoparticles having an interior space.

Abstract translation: 公开了具有优异T2对比效果的磁共振成像用氧化铁纳米造影剂，也可用作药物的储存或载体等。 氧化铁纳米对比剂可以通过以下步骤制备：用有机溶剂中的选自聚乙二醇 - 磷脂缀合物，葡聚糖，壳聚糖，二巯基琥珀酸及其混合物的涂层材料涂覆疏水性FeO纳米颗粒的表面， 形成具有亲水表面和在水中分散性的亲水性FeO纳米颗粒; 将亲水性FeO纳米颗粒分散在水中以氧化FeO; 并将氧化的亲水性FeO纳米颗粒暴露于酸性缓冲液以溶解和除去内部未氧化的FeO部分，从而形成具有内部空间的Fe 3 O 4纳米颗粒。

公开(公告)号：US20130150731A1

公开(公告)日：2013-06-13

申请号：US13708329

申请日：2012-12-07

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Ki Soo Chang ,  Seon Young Ryu ,  Sun Cheol Yang ,  Geon Hee Kim ,  Hae Young Choi

IPC: A61B1/07 ,  A61B5/00

CPC classification number: A61B1/07 ,  A61B1/00096 ,  A61B1/0011 ,  A61B1/00167 ,  A61B5/0071

Abstract: Provided is an imaging system which includes an optical fiber array probe unit integrated with an endoscope unit, thereby simultaneously measuring structural information and functional information of a sample. The optical fiber array probe unit includes an optical fiber array probe integrated with lenses including an optical fiber lens with a lens surface of a predetermined radius of curvature in which one ends of optical fibers are integrally connected with each other by heating a predetermined region including the one ends of two of the optical fibers using a heating means, as an optical fiber array probe integrated lens on which the light transmitted from the light source is incident and which guides light reflected from the sample, and a detector for selectively detecting the light transmitted from the optical fiber array probe integrated with lenses in a predetermined range of wavelength.

Abstract translation: 提供了一种成像系统，其包括与内窥镜单元集成的光纤阵列探针单元，从而同时测量样品的结构信息和功能信息。 光纤阵列探针单元包括与透镜组合的光纤阵列探针，该透镜包括具有预定曲率半径的透镜表面的光纤透镜，其中光纤的一端通过加热包括 使用加热装置的两根光纤的一端作为光纤阵列探针集成透镜，其中从光源透射的光入射到该光纤阵列探针集成透镜，并且其引导从样品反射的光;以及检测器，用于选择性地检测透射的光 从与预定波长范围的透镜集成的光纤阵列探针。

公开(公告)号：US20130133402A1

公开(公告)日：2013-05-30

申请号：US13334967

申请日：2011-12-22

Applicant: Sanggoo KIM

Inventor： Sanggoo KIM

IPC: G01N30/60 ,  G03F7/20

CPC classification number: G01N30/6095 ,  B01L3/502707 ,  G01N2030/303

Abstract: Disclosed herein are a multi-layer chip for gas chromatography and a method of fabricating the multi-layer chip. The multi-layer chip is fabricated by: forming fine channels at the same positions of a plurality of substrates using only a single photo mask and an alignment key; and stacking the substrates. That is, the multi-layer chip can be fabricated by a simple method, and the total length of the fine channels can be increase without a limit by stacking more substrates. In addition, layers of the substrates can be coated with different stationary phases, and a temperature control device can be attached to heat transfer contact portions of the multi-layer chip for controlling the temperature of the multi-layer chip rapidly and precisely. Therefore, the multi-layer chip may be useful for high-separability gas chromatography to separate and analyze an infinitesimal amount of a sample.

Abstract translation: 本文公开了用于气相色谱的多层芯片和制造多层芯片的方法。 多层芯片通过以下方式制造：仅使用单个光掩模和对准键在多个基板的相同位置处形成精细通道; 并堆叠基板。 也就是说，可以通过简单的方法制造多层芯片，并且可以通过堆叠更多的基板而不受限制地增加精细通道的总长度。 此外，基板的层可以涂覆有不同的固定相，并且温度控制装置可以附接到多层芯片的传热接触部分，以快速且精确地控制多层芯片的温度。 因此，多层芯片可用于高分离性气相色谱分离和分析无穷小的样品。

公开(公告)号：US08357348B2

公开(公告)日：2013-01-22

申请号：US13030802

申请日：2011-02-18

Applicant: Hae Jin Kim ,  Soon Chang Lee ,  Jin Bae Lee

Inventor： Hae Jin Kim ,  Soon Chang Lee ,  Jin Bae Lee

IPC: C01G23/047

CPC classification number: C01G23/047 ,  B01J21/063 ,  B01J35/0013 ,  B01J35/004 ,  B01J37/033 ,  B01J37/10 ,  B82Y30/00 ,  C01G23/053 ,  C01P2002/72 ,  C01P2004/04 ,  C01P2004/64

Abstract: The present invention relates to a method for preparing anatase-type titanium dioxide (TiO2) nanoparticles, the method comprising the steps of: uniformly mixing titanium n-butoxide and cetyltrimethyl ammonium salt (CTAS) in water; subjecting the mixture to hydrothermal treatment at a temperature of 60˜120° C.; and collecting anatase-type titanium dioxide nanoparticles produced by the hydrothermal treatment and drying the collected nanoparticles. According to the present invention, anatase-type titanium dioxide nanoparticles having excellent crystallinity can be easily prepared in large amounts by a simple process without needing heat treatment.

Abstract translation: 本发明涉及一种制备锐钛矿型二氧化钛（TiO2）纳米颗粒的方法，所述方法包括以下步骤：在水中均匀混合正丁醇钛和十六烷基三甲基铵盐（CTAS）; 在60〜120℃的温度下对混合物进行水热处理; 并收集通过水热处理制备的锐钛矿型二氧化钛纳米颗粒并干燥收集的纳米颗粒。 根据本发明，可以通过简单的工艺容易地制备具有优异结晶度的锐钛矿型二氧化钛纳米颗粒，而不需要热处理。

公开(公告)号：US20120277571A1

公开(公告)日：2012-11-01

申请号：US13094204

申请日：2011-04-26

Applicant: Gyunggoo Cho ,  Namkug Kim ,  June-Goo Lee ,  Youngkyu Song ,  Hengjun J Kim ,  Chaejoon Cheong

Inventor： Gyunggoo Cho ,  Namkug Kim ,  June-Goo Lee ,  Youngkyu Song ,  Hengjun J Kim ,  Chaejoon Cheong

IPC: A61B5/055 ,  G06K9/00

CPC classification number: A61B5/055 ,  A61B5/4504 ,  A61B5/4509 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/20044 ,  G06T2207/30008

Abstract: Disclosed is a method for measuring trabecular bone parameters from MRI images, including: scanning an experimental group with a 3D MRI scanner; segmenting the MRI images to extract bone area and perform skeletonization of the bone area; detecting end-point, joint and branch voxels in the skeleton to analyze bone structure; and measuring trabecular bone parameters based on the result of the structural analysis. The method enables diagnosing osteoporosis.

Abstract translation: 公开了一种从MRI图像测量小梁骨参数的方法，包括：用3D MRI扫描仪扫描实验组; 分割MRI图像以提取骨区域，并执行骨区域的骨架化; 检测骨骼中的端点，关节和分支体素来分析骨骼结构; 并根据结构分析结果测量小梁骨参数。 该方法能够诊断骨质疏松症。