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21.
公开(公告)号:US20230243852A1
公开(公告)日:2023-08-03
申请号:US18160000
申请日:2023-01-26
Applicant: IDEXX LABORATORIES, INC.
Inventor: Sarah Maier PETERSON , Yerramilli V.S.N. MURHTY
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2333/775 , G01N2333/8139 , G01N2800/56 , G01N2800/347
Abstract: The disclosure provides methods and compositions for detection and differentiation of stable CKD and progressive CKD in mammals.
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公开(公告)号:US11618915B2
公开(公告)日:2023-04-04
申请号:US16193695
申请日:2018-11-16
Applicant: IDEXX Laboratories Inc.
Inventor: Daniel H. Broder , Lawrence G. Chapper , Veronica L. Newport , Julie E. Rollins , Brian M. Swalla , Scott W. Wagner , David L. White
Abstract: A sample testing apparatus includes a sample tray defining a planar surface and a plurality of wells recessed relative to the planar surface, and a lid member configured to be sealed about the planar surface of the sample tray. The lid member includes an adhesive layer configured to be sealed to the planar surface of the sample tray, a breathable film layer disposed about the adhesive layer, and a backing layer disposed about the breathable film layer. Methods of using the sample testing apparatus for testing a sample and kits to facilitate such testing are also provided.
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公开(公告)号:US11435365B2
公开(公告)日:2022-09-06
申请号:US16571345
申请日:2019-09-16
Applicant: IDEXX Laboratories, Inc.
Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.
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公开(公告)号:US20220196672A1
公开(公告)日:2022-06-23
申请号:US17554557
申请日:2021-12-17
Applicant: IDEXX LABORATORIES, INC.
Inventor: Joshua Michael BOUCHER , Anton MESTEK, JR. , Clever MADRID , Jesse Stephen BUCH
IPC: G01N33/68 , G01N33/569 , C07K14/29
Abstract: Provided herein are compositions and methods for detection and treatment of Rocky Mountain spotted fever (“RMSF”). The compositions specifically detect Rickettsia rickettsii and do not cross-react with other Rickettsia species providing rapid and accurate detection and diagnosis of RMSF.
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25.
公开(公告)号:US20220099594A1
公开(公告)日:2022-03-31
申请号:US17490461
申请日:2021-09-30
Applicant: IDEXX Laboratories, Inc.
Inventor: David C. Giroux , Nathanael Williams
IPC: G01N21/956 , G01N35/00
Abstract: A Z-axis measurement fixture used for testing whether a chemical reagent test slide exhibits Z-axis variability, which may affect measurements performed by an automated chemical analyzer using such test slides, includes a planar main body that holds three stainless steel balls, each ball having a known and calibrated diameter. Portions of the stainless steel balls extend outwardly from the top wall and the bottom wall of the planar main body. A chemical reagent test slide is placed on the fixture to rest on and be supported at three points by the portions of the stainless steel balls which project outwardly from the top wall of the planar main body. The fixture is placed on the surface of a gauge block of an optical measurement system such that the lower portions of the three stainless steel balls will rest on the gauge block of the optical measurement system.
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26.
公开(公告)号:US20210278431A1
公开(公告)日:2021-09-09
申请号:US17195020
申请日:2021-03-08
Applicant: IDEXX Laboratories, Inc.
Inventor: Jesse Daniel Faller , Robert W. Lachapelle , Dominic Pelletier
IPC: G01N35/10
Abstract: An insert mounted in a mixing cup and used by an automated chemical analyzer for removing a targeted component of a liquid sample includes a porous matrix formed of or carrying in an immobilized state functionalized particles having properties such that the targeted component of the liquid sample adheres to the functionalized particles. When the liquid sample is expelled from a disposable tip fitted on the end of a pipette forming part of the automated chemical analyzer into the mixing cup, the liquid sample is drawn into the matrix of the insert by capillary action, whereupon the targeted component of the liquid sample adheres to the immobilized functionalized particles of the matrix.
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公开(公告)号:US10942180B2
公开(公告)日:2021-03-09
申请号:US16539238
申请日:2019-08-13
Applicant: IDEXX Laboratories, Inc. , Monsanto Company
Inventor: David Allen Elsemore , Jinming Geng , Laurie A. Flynn , Michael Crawford
IPC: G01N33/00 , G01N33/569 , G01N33/53 , G01N33/68
Abstract: Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
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公开(公告)号:US20190316171A1
公开(公告)日:2019-10-17
申请号:US16362478
申请日:2019-03-22
Applicant: IDEXX LABORATORIES, INC.
Inventor: Giosi Farace , Jon Braff , Murthy VSN Yerramilli
Abstract: The disclosure relates generally to methods for measuring bacteria in biological samples. More particularly, the disclosure relates to methods for measuring bacteria using an aqueous clearance solution.
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公开(公告)号:US20190112658A1
公开(公告)日:2019-04-18
申请号:US16227732
申请日:2018-12-20
Applicant: IDEXX Laboratories, Inc.
Inventor: Christian Leutenegger , Michael John Angelichio
IPC: C12Q1/6876 , C12Q1/686 , C12Q1/6844
Abstract: The invention provides components and methods for polymerase chain reaction assays. The assays minimize both handling of material and time spent running samples. For example, a single internal positive control (IPC) polynucleotide pair can provide a means to ensure proper nucleic acid purification for both RNA and DNA test targets. Additionally, standard cycling conditions for all diagnostic tests allow the user to run both RNA and DNA targets side-by-side.
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公开(公告)号:US09797916B2
公开(公告)日:2017-10-24
申请号:US14592282
申请日:2015-01-08
Applicant: IDEXX Laboratories, Inc.
Inventor: David Lance Connolly , Mark Raymond Dumont , Justin Jay Griffin , John Harvey McGibbon , Garland Christian Misener , Jeffrey Eric Phelps , Carl Russell Rich , Kenneth Eugene Smith , Dragan Vidacic
CPC classification number: G01N35/0099 , B25J9/1697 , B25J19/021 , G01N1/312 , G01N35/00029 , G01N35/00732 , G01N35/025 , G01N35/04 , G01N35/109 , G01N2035/00039 , G01N2035/00079 , G01N2035/00138 , G01N2035/00356 , G01N2035/0405 , G01N2035/0449 , G01N2035/103 , Y10S901/09 , Y10S901/41
Abstract: A medical apparatus for analyzing fluid samples includes an outer casing, a slide loading mechanism disposed within the outer casing for loading fluid analysis slides, a slide ejecting mechanism disposed within the outer casing for ejecting fluid analysis slides, an evaporation cap opening mechanism disposed within the outer casing for opening an evaporation cap, an evaporation cap closing mechanism disposed within the outer casing for closing an evaporation cap, a drawer locking mechanism disposed within the outer casing for locking a drawer associated with the outer casing, a camera disposed within the outer casing, and a robot disposed within the outer casing. The robot is movable in three dimensions and has means for conducting three or more of the following operations: slide loading; slide ejecting; evaporation cap opening; evaporation cap closing; drawer locking; and camera manipulation.
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