公开(公告)号：US20100260778A1

公开(公告)日：2010-10-14

申请号：US12067158

申请日：2006-09-20

Applicant: Yuan-Ping Pang ,  Charles B. Millard ,  Jewn Giew Park ,  Jing Tang ,  James J. Schmidt

Inventor： Yuan-Ping Pang ,  Charles B. Millard ,  Jewn Giew Park ,  Jing Tang ,  James J. Schmidt

IPC: A61K31/506 ,  A61K39/40 ,  C12N9/99 ,  A61K31/43 ,  A61K31/4439 ,  A61K31/404 ,  A61K31/381 ,  C07D409/14 ,  C07D409/06 ,  C07D333/24 ,  A61P31/04

CPC classification number: A61K31/675

Abstract: Small-molecule inhibitors of Botulinum toxin, including BoNTA, BoNTD and BoNTE are provided, as well as methods of using the inhibitors.

Abstract translation: 提供了肉毒杆菌毒素的小分子抑制剂，包括BoNTA，BoNTD和BoNTE，以及使用抑制剂的方法。

公开(公告)号：US07805028B2

公开(公告)日：2010-09-28

申请号：US12253123

申请日：2008-10-16

Applicant: Zhiyong Li ,  Michael Tan ,  Shih-Yuan Wang ,  Wei Wu ,  Jing Tang

Inventor： Zhiyong Li ,  Michael Tan ,  Shih-Yuan Wang ,  Wei Wu ,  Jing Tang

IPC: G02B6/00 ,  G02B6/32 ,  G02B6/10

CPC classification number: G02B6/02328 ,  B82Y20/00 ,  G01N21/05 ,  G01N21/31 ,  G01N21/645 ,  G01N21/658 ,  G01N2021/0346 ,  G01N2021/052 ,  G01N2021/6467 ,  G01N2021/7763 ,  G01N2021/7783 ,  G02B6/1226

Abstract: An optical sensor, sensing system and method of sensing employ a half-core hollow optical waveguide adjacent to a surface of an optical waveguide layer of a substrate. The half-core hollow optical waveguide and the adjacent optical waveguide layer cooperatively provide both an optical path that confines and guides an optical signal and an internal hollow channel. The optical path and channel extend longitudinally along a hollow core of the half-core hollow optical waveguide. The system further includes an optical source at an input of the optical path and an optical detector at an output of the optical path. A spectroscopic interaction between an analyte material that is introduced into the channel and an optical signal propagating along the optical path determines a characteristic of the analyte material.

Abstract translation: 光学传感器，感测系统和感测方法使用与衬底的光波导层的表面相邻的半芯空心光波导。 半芯空心光波导和相邻的光波导层协同地提供限制和引导光信号和内部中空通道的光路。 光路和通道沿半芯空心光波导的中空芯纵向延伸。 该系统还包括在光路的输入处的光源和在光路的输出处的光学检测器。 引入到通道中的分析物质与沿光路传播的光信号之间的光谱相互作用决定了分析物质的特性。

公开(公告)号：US20100174196A1

公开(公告)日：2010-07-08

申请号：US12663166

申请日：2008-06-20

Applicant: S. Eric Ryan ,  Jing Tang

Inventor： S. Eric Ryan ,  Jing Tang

IPC: A61B6/00 ,  A61N5/06 ,  A61M29/00 ,  A61F2/84

CPC classification number: A61B5/0071 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/02007 ,  A61B5/6852 ,  A61F2/856 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/821 ,  A61M25/1002 ,  A61M25/1011 ,  A61M2025/0166 ,  A61M2025/1052

Abstract: A system for treating a body lumen comprises a catheter including a flexible conduit that is elongated along a longitudinal axis and suitable for insertion into a body lumen, the conduit having a proximal end and a distal end, one or more waveguides integrated with the flexible conduit, the one or more waveguides constructed and arranged to deliver and collect radiation concentrated along a predetermined radial axis of the conduit, the predetermined radial axis of the conduit substantially aligned with respect to at least one therapy delivery component of the catheter, at least one radiation source connected to a transmission input of the one or more waveguides integrated with the flexible conduit, and at least one optical detector connected to a transmission output of the one or more waveguides integrated with the flexible conduit.

Abstract translation: 用于治疗体腔的系统包括导管，其包括沿着纵向轴线细长并适于插入体腔的柔性导管，所述导管具有近端和远端，一个或多个与柔性导管一体化的波导 所述一个或多个波导被构造和布置成递送和收集沿着所述导管的预定径向轴线集中的辐射，所述导管的预定径向轴线相对于所述导管的至少一个治疗递送部件基本对齐，至少一个辐射 源连接到与柔性导管集成的一个或多个波导的传输输入，以及连接到与柔性导管集成的一个或多个波导的传输输出的至少一个光学检测器。

公开(公告)号：US20100075503A1

公开(公告)日：2010-03-25

申请号：US12234101

申请日：2008-09-19

Applicant: CHRISTOPHER DENNIS BENCHER ,  Jing Tang

Inventor： CHRISTOPHER DENNIS BENCHER ,  Jing Tang

IPC: H01L21/311

CPC classification number: H01L21/3086 ,  H01L21/3088 ,  Y10S438/95

Abstract: Embodiments of the present invention pertain to methods of forming patterned features on a substrate having an increased density (i.e. reduced pitch) as compared to what is possible using standard photolithography processing techniques using a single high-resolution photomask while also allowing both the width of the patterned features and spacing (trench width) between the patterned features to vary within an integrated circuit.

Abstract translation: 本发明的实施例涉及在使用单个高分辨率光掩模的标准光刻处理技术的情况下与具有增加的密度（即减小的间距）的衬底上形成图案化特征的方法，同时还允许 图案化特征和图案化特征之间的间隔（沟槽宽度）在集成电路内变化。

公开(公告)号：US20100062603A1

公开(公告)日：2010-03-11

申请号：US12558370

申请日：2009-09-11

Applicant: Udayan Ganguly ,  Yoshita Yokota ,  Jing Tang ,  Sunderraj Thirupapuliyur ,  Christopher Sean Olsen ,  Shiyu Sun ,  Tze Wing Poon ,  Wei Liu ,  Johanes Swenberg ,  Vicky U. Nguyen ,  Swaminathan Srinivasan ,  Jacob Newman

Inventor： Udayan Ganguly ,  Yoshita Yokota ,  Jing Tang ,  Sunderraj Thirupapuliyur ,  Christopher Sean Olsen ,  Shiyu Sun ,  Tze Wing Poon ,  Wei Liu ,  Johanes Swenberg ,  Vicky U. Nguyen ,  Swaminathan Srinivasan ,  Jacob Newman

IPC: H01L21/311 ,  H01L21/28

CPC classification number: H01L29/788 ,  H01L21/67167 ,  H01L21/67207 ,  H01L21/76232 ,  H01L27/11521

Abstract: Semiconductor devices suitable for narrow pitch applications and methods of fabrication thereof are described herein. In some embodiments, a semiconductor device may include a floating gate having a first width proximate a base of the floating gate that is greater than a second width proximate a top of the floating gate. In some embodiments, a method of shaping a material layer may include (a) oxidizing a surface of a material layer to form an oxide layer at an initial rate; (b) terminating formation of the oxide layer when the oxidation rate is about 90% or below of the initial rate; (c) removing at least some of the oxide layer by an etching process; and (d) repeating (a) through (c) until the material layer is formed to a desired shape. In some embodiments, the material layer may be a floating gate of a semiconductor device.

Abstract translation: 适用于窄间距应用的半导体器件及其制造方法在本文中描述。 在一些实施例中，半导体器件可以包括具有接近浮动栅极的基极的第一宽度的浮动栅极，该第一宽度大于靠近浮动栅极顶部的第二宽度。 在一些实施例中，成形材料层的方法可以包括（a）氧化材料层的表面以以初始速率形成氧化物层; （b）当氧化速率为初始速率的约90％或更低时终止氧化物层的形成; （c）通过蚀刻工艺去除至少一些氧化物层; 和（d）重复（a）到（c）直到材料层形成所需的形状。 在一些实施例中，材料层可以是半导体器件的浮置栅极。

公开(公告)号：US20100021366A1

公开(公告)日：2010-01-28

申请号：US11752968

申请日：2007-05-24

Applicant: Qingyuan Hu ,  Yunfeng Lu ,  Jing Tang ,  Mei Cai

Inventor： Qingyuan Hu ,  Yunfeng Lu ,  Jing Tang ,  Mei Cai

IPC: C01B31/02

CPC classification number: B01J20/28083 ,  B01J20/20 ,  B01J21/18 ,  B01J35/1061 ,  B01J37/0018 ,  B01J37/084 ,  C01B32/00

Abstract: Carbon with mesopores (about two to fifteen nanometers in average pore size) is made using sucrose as a source of carbon, and silica and phosphoric acid as templates for the mesopore structure in the carbon. A silica sol is prepared in a water/ethanol medium and sucrose is dispersed in the sol. Phosphoric acid may be added to the sol to control pore size in the mesopore size range. The sol is dried, carbonized, and the silica and phosphate materials removed by leaching. The residue is a mesoporous carbon mass having utility as a catalyst support, gas absorbent, and the like.

Abstract translation: 使用蔗糖作为碳源制成具有介孔（平均孔径约2至15纳米）的碳，并且将二氧化硅和磷酸用作碳中的中孔结构的模板。 在水/乙醇介质中制备硅溶胶，并将蔗糖分散在溶胶中。 可以将磷酸加入到溶胶中以控制中孔尺寸范围内的孔径。 将溶胶干燥，碳化，并通过浸出除去二氧化硅和磷酸盐物质。 残留物是具有用作催化剂载体，气体吸收剂等的介孔碳质量。

公开(公告)号：US20080125634A1

公开(公告)日：2008-05-29

申请号：US11762956

申请日：2007-06-14

Applicant: S. Eric Ryan ,  Jing Tang

Inventor： S. Eric Ryan ,  Jing Tang

IPC: A61B18/20 ,  A61B5/1459 ,  A61B10/02 ,  A61M25/00

CPC classification number: A61M25/06 ,  A61B5/01 ,  A61B5/145 ,  A61B10/04 ,  A61B18/24 ,  A61B2010/045 ,  A61B2017/00061 ,  A61B2017/00247 ,  A61B2017/003 ,  A61B2017/22077 ,  A61B2018/00392 ,  A61B2018/2238 ,  A61M25/0147 ,  A61M2025/0096

Abstract: A method and apparatus for analyzing and treating internal tissues and, in particular, tissues affected by myocardial infarct. The apparatus includes a catheterized device integrating an optical probe and treatment delivery system. The probe component includes fiber optic lines that can be used in conjunction with infrared spectroscopy to analyze various characteristics of tissues, including chemical, blood, and oxygen content, in order to locate those tissues associated with myocardial infarct, to determine the best location for applying treatment, and to monitor treatment and its effects. Physically integrated with the probe component is a treatment component for delivering treatments including stem cell and gene therapy, known for having beneficial effects on tissues associated with myocardial infarct. A control system coordinates operation of the catheter, including performing chemometric analysis with the use of model data, and for providing control and visual feedback to an operator.

Abstract translation: 一种用于分析和治疗内部组织，特别是受到心肌梗死影响的组织的方法和装置。 该装置包括集成光学探针和治疗递送系统的导管装置。 探针组件包括可以与红外光谱结合使用以分析组织的各种特征（包括化学，血液和氧含量）的光纤线，以便定位与心肌梗死相关的那些组织，以确定应用的最佳位置 治疗，并监测治疗及其影响。 与探针组分物理整合是用于递送治疗的治疗组件，包括干细胞和基因治疗，已知对于与心肌梗死相关的组织具有有益作用。 控制系统协调导管的操作，包括使用模型数据执行化学计量分析，以及向操作者提供控制和视觉反馈。

公开(公告)号：US07376456B2

公开(公告)日：2008-05-20

申请号：US10635330

申请日：2003-08-05

Applicant: Barbara J. Marshik-Geurts ,  Jing Tang ,  Andres F. Zuluaga

Inventor： Barbara J. Marshik-Geurts ,  Jing Tang ,  Andres F. Zuluaga

IPC: A61B6/00

CPC classification number: A61B5/0086 ,  A61B5/0075 ,  G06F19/00

Abstract: The invention relates to methods and devices for characterizing tissue in vivo, e.g., in walls of blood vessels, to determine whether the tissue is healthy or diseased, and include methods of displaying results with or without thresholds.

Abstract translation: 本发明涉及用于表征体内组织的方法和装置，例如在血管壁中，以确定组织是健康还是患病，并且包括显示具有或不具有阈值的结果的方法。

公开(公告)号：US07189359B2

公开(公告)日：2007-03-13

申请号：US10900649

申请日：2004-07-28

Applicant: Shih-Jun Yuan ,  Jing-Tang Yang ,  Jer-Liang Yeh ,  Chih-Sheng Yu ,  Yi-Chiuen Hu ,  Chien-Jen Chen

Inventor： Shih-Jun Yuan ,  Jing-Tang Yang ,  Jer-Liang Yeh ,  Chih-Sheng Yu ,  Yi-Chiuen Hu ,  Chien-Jen Chen

IPC: G01N15/06 ,  B32B5/02 ,  B32B27/04 ,  B32B27/12 ,  B32B27/00

CPC classification number: G01N27/745 ,  G01N33/5438 ,  Y10T436/11

Abstract: A detecting device for biochemical detections is provided. The detecting device includes a first substrate, a magnetic layer located on the first substrate, an isolation layer located on the magnetic layer, at least a first electrode located on the isolation layer, a first dielectric layer located on the first electrode, a first hydrophobic layer located on the first dielectric layer, a second substrate, at least a second electrode located on the second substrate and having a cathode and an anode, a second dielectric layer located on the second electrode' and a second hydrophobic layer located on the second dielectric layer. The first electrode is zigzag-shaped, and the cathode and the anode of the second electrode are comb-shaped and interlaced with each other.

Abstract translation: 提供了用于生化检测的检测装置。 所述检测装置包括第一基板，位于所述第一基板上的磁性层，位于所述磁性层上的隔离层，位于所述隔离层上的至少第一电极，位于所述第一电极上的第一电介质层， 位于第一电介质层上的第二电介质层，第二衬底，位于第二衬底上的至少第二电极，具有阴极和阳极，位于第二电极上的第二电介质层和位于第二电介质上的第二疏水层 层。 第一电极是锯齿形的，并且第二电极的阴极和阳极是梳状的并且彼此交错。

公开(公告)号：US20060186323A1

公开(公告)日：2006-08-24

申请号：US10115810

申请日：2002-04-03

Applicant: Ying Ruan ,  Jing Tang

Inventor： Ying Ruan ,  Jing Tang

IPC: G02B6/42

CPC classification number: G01N21/552 ,  B60S1/0822 ,  B60S1/0833 ,  B60S1/0885 ,  G01N2021/157 ,  G01N2201/0691

Abstract: A photo-electronic window and windshield fog-rain detecting system comprising two sub-systems from a film-attached fog detecting assembly, a regular detecting and a rain detecting assembly, and a corresponding Gate-relation circuits to couple the two assemblies with each other electronically to make multi function detecting. The regular detecting assembly uses an emitter to transmit light signals towards a test area on the windshield and uses a sensor to receive signals portion from the test area to sense the changes in the received signal portion, caused by fog or rain, so as to verify the existence of for or rain on the windshield. The film-attached assembly is formed by applying an appropriate opaque thin film material to the test area, such as foil, plastic, paint, etc., to avoid meeting any influence by the outside fog and rain, so as to be able to reliably detect fog on the interior surface of windshield and handle the defogger. The rain detecting assembly is formed by using a covering mounting structure to completely cover the detecting devices on the interior surface of windshield to avoid meeting any inside fog, so as to be able to reliably detect outside fog or rain on the exterior surface and handle the wipers. By coupling any two of three assemblies together electronically, a reliably multi function fog and rain detector is built up to instantly actuate a right tool, wipers or the vehicle defogger, to clear the windshield up when fog or rain is on.

Abstract translation: 一种光电窗口和挡风玻璃雾雨检测系统，包括来自胶片附着的雾检测组件，常规检测和雨检测组件的两个子系统以及将两个组件彼此耦合的相应的Gate-Relationship电路 以电子方式进行多功能检测。 常规检测组件使用发射器向挡风玻璃上的测试区域发射光信号，并使用传感器从测试区域接收信号部分，以感测由雾或雨引起的接收信号部分的变化，以便验证 在挡风玻璃上存在或下雨。 通过将适当的不透明薄膜材料施加到诸如箔，塑料，油漆等的测试区域以避免外界雾和雨的影响而形成胶片附接组件，从而能够可靠地 检测挡风玻璃内表面的雾，并处理除雾器。 雨检测组件通过使用覆盖安装结构来形成，以完全覆盖挡风玻璃内表面上的检测装置，以避免遇到任何内部雾，从而能够可靠地检测外表面的外部雾或雨，并处理 雨刷 通过将三个组件中的任何两个组合在一起电子，建立可靠的多功能雾和雨检测器，以立即启动正确的工具，擦拭器或车辆除雾器，以防止雾或雨起作用。