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公开(公告)号：US20180099999A1
公开(公告)日：2018-04-12
申请号：US15842062
申请日：2017-12-14
Applicant: Spogen Biotech Inc.
Inventor： Brian Thompson , Ashley Siegel
IPC: C07K14/32 , A01N37/44 , A01N63/02 , C12N1/20 , A61L2/18 , E21B43/16 , C12N3/00 , C12N15/62 , C12N15/75 , C12P21/02 , C09K8/62 , C02F3/34 , A61K39/00 , C02F103/00 , C02F103/06 , C02F103/10 , C02F103/14 , C02F103/26 , C02F103/28 , C02F103/16
CPC classification number: C07K14/32 , A01N37/44 , A01N63/02 , A23K10/18 , A23K20/147 , A61K39/00 , A61L2/18 , C02F3/342 , C02F3/348 , C02F2101/10 , C02F2101/30 , C02F2103/002 , C02F2103/003 , C02F2103/007 , C02F2103/06 , C02F2103/10 , C02F2103/14 , C02F2103/16 , C02F2103/26 , C02F2103/28 , C07K2319/01 , C07K2319/035 , C07K2319/40 , C09K8/62 , C09K2208/24 , C12N1/20 , C12N3/00 , C12N15/62 , C12N15/75 , C12P21/02 , E21B43/16
Abstract: Fusion proteins containing a targeting sequence, an exosporium protein, or an exosporium protein fragment that targets the fusion protein to the exosporium of a Bacillus cereus family member are provided. Recombinant Bacillus cereus family members expressing such fusion proteins are also provided. Genetically inactivated Bacillus cereus family members and recombinant Bacillus cereus family members that overexpress exosporium proteins are also provided. Seeds coated with the recombinant Bacillus cereus family members and methods for using the recombinant Bacillus cereus family members (e.g., for stimulating plant growth) are also provided. Various modifications of the recombinant Bacillus cereus family members that express the fusion proteins are further provided. Fusion proteins comprising a spore coat protein and a protein or peptide of interest, recombinant bacteria that express such fusion proteins, seeds coated with such recombinant bacteria, and methods for using such recombinant bacteria (e.g., for stimulating plant growth) are also provided.
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22.发明申请公开(公告)号：US20170356002A1
公开(公告)日：2017-12-14
申请号：US15460468
申请日：2017-03-16
Applicant: Spogen Biotech Inc.
Inventor： Brian M. Thompson , Jorg Augustin
CPC classification number: C12N15/8249 , A01H5/00 , A01N63/00 , C05B15/00 , C05C9/00 , C05F11/08 , C05G3/02 , C07K14/415 , C12N1/20 , C12N9/78 , C12N15/8237 , C12N15/8279 , C12Y302/01 , C12Y305/99007 , C12Y402/0202 , Y02A40/229 , Y02P60/218
Abstract: Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided. Plant seeds coated with free enzymes or recombinant microorganisms that overexpress enzymes are also provided. Compositions comprising a fertilizer and an enzyme or a recombinant microorganism that overexpresses an enzyme are provided. Modified enzymes having ACC deaminase activity, recombinant microorganisms expressing the modified enzymes, plant seeds treated with the modified enzymes or recombinant microorganisms, and methods for stimulating plant growth and/or promoting plant health using the modified enzymes or recombinant microorganisms are also provided.
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公开(公告)号：US20170290339A1
公开(公告)日：2017-10-12
申请号：US15511864
申请日：2015-09-17
Applicant: Bayer CropScience LP , Spogen Biotech Inc.
Inventor： Damian Curtis , Brian THOMPSON
CPC classification number: A01N63/00 , A01N43/22 , A01N43/90 , A01N47/22 , C12Y301/01 , C12Y302/01004 , C12Y302/01132 , Y02A50/356 , A01N43/56 , A01N47/40 , A01N53/00
Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.
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24.发明申请FUSION PROTEINS AND METHODS FOR STIMULATING PLANT GROWTH, PROTECTING PLANTS FROM PATHOGENS, AND IMMOBILIZING BACILLUS SPORES ON PLANT ROOTS 有权用于刺激植物生长的融合蛋白质和方法，保护植物从病原体和植物育苗中的苗木运动公开(公告)号：US20140274707A1
公开(公告)日：2014-09-18
申请号：US14213525
申请日：2014-03-14
Applicant: Spogen Biotech Inc.
Inventor： Brian Thompson , Katie Thompson
IPC: A01N63/02
CPC classification number: C07K14/32 , A01N37/46 , A01N37/48 , A01N63/00 , A01N63/02 , C07K2319/035 , C12N9/0095 , C12N9/16 , C12N9/20 , C12N9/2402 , C12N9/2437 , C12N9/48 , C12Y118/06001 , C12Y301/01003 , C12Y301/03008 , C12Y302/01004 , C12Y304/00
Abstract: The present invention is generally directed to fusion proteins containing a targeting sequence that targets the fusion protein to the exosporium of a Bacillus cereus family member. The invention also relates to recombinant Bacillus cereus family members expressing such fusion proteins, formulations containing the recombinant Bacillus cereus family members expressing the fusion proteins. Methods for stimulating plant growth and for protecting plants from pathogens by applying the recombinant Bacillus cereus family members or the formulations to plants or a plant growth medium are also described. The invention also relates to methods for immobilizing spores of a recombinant Bacillus cereus family member expressing a fusion protein on plant roots.
Abstract translation: 本发明一般涉及含有将融合蛋白靶向蜡状芽孢杆菌家族成员的外植体的靶向序列的融合蛋白。 本发明还涉及表达这种融合蛋白的重组蜡状芽孢杆菌家族成员，包含表达融合蛋白的重组蜡状芽孢杆菌家族成员的制剂。 还描述了通过将重组蜡状芽孢杆菌家族成员或制剂施用于植物或植物生长培养基来刺激植物生长和保护植物免受病原体的方法。 本发明还涉及将表达融合蛋白的重组蜡状芽孢杆菌家族成员的孢子固定在植物根上的方法。
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公开(公告)号：US12268727B2
公开(公告)日：2025-04-08
申请号：US17350746
申请日：2021-06-17
Applicant: Spogen Biotech Inc.
Inventor： Brian Thompson , Michelle Leslie
IPC: A61K38/16 , A01N37/46 , A01N63/10 , A01N63/22 , A01N63/25 , A01N63/50 , C07K14/195 , C07K14/21 , C07K14/245 , C07K14/27 , C07K14/32 , C12N1/20 , C12N15/82 , C12P21/02
Abstract: Bioactive priming polypeptides are provided that are useful when applied to plants in agricultural formulations. Methods of using the formulations containing the bioactive priming polypeptides are also provided which are applied exogenously to the surface of a plant or a plant cell membrane or endogenously to the interior of a plant or to a plant cell. The bioactive priming polypeptides when applied to a plant, a plant part, or a plant growth medium or a rhizosphere in an area surrounding the plant or the plant part increase growth, yield, health, longevity, productivity, and/or vigor of a plant or a plant part and/or decrease abiotic stress in the plant or the plant part and/or protect the plant or the plant part from disease, insects and/or nematodes, and/or increase the innate immune response of the plant or the plant part and/or change plant architecture.
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Patent Agency Ranking
公开(公告)号：US20250093260A1
公开(公告)日：2025-03-20
申请号：US18958925
申请日：2024-11-25
Applicant: Spogen Biotech Inc.
Inventor： Brian M. Thompson
IPC: G01N21/31 , G01J3/02 , G01N21/01 , G01N21/05 , G01N21/17 , G01N21/25 , G01N21/3577 , G01N21/64 , G01N21/77 , G01N21/78 , G01N21/80
Abstract: Systems, devices, and methods for detecting agrochemicals in environments associated with agricultural equipment are described. Certain agrochemicals that are formulated for being detected using the systems, devices, and methods disclosed herein are also described. The devices, systems, and methods disclosed herein are generally configured to use spectral characteristics to detect agrochemicals in an environment associated with agricultural equipment. The spectral characteristics can be analyzed in various ways to provide different types of information about the agrochemicals and/or the environment.
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27.发明公开公开(公告)号：US20240228396A9
公开(公告)日：2024-07-11
申请号：US18476270
申请日：2023-09-27
Applicant: Spogen Biotech Inc.
Inventor： Brian M. Thompson , Jorg Augustin
IPC: C05F11/08 , A01N63/50 , C05B15/00 , C05C9/00 , C05F17/20 , C05G3/60 , C07K14/415 , C12N1/20 , C12N9/78 , C12N15/82
CPC classification number: C05F11/08 , A01N63/50 , C05B15/00 , C05C9/00 , C05F17/20 , C05G3/60 , C07K14/415 , C12N1/20 , C12N9/78 , C12N15/8237 , C12N15/8249 , C12N15/8279 , C12Y302/01 , C12Y305/99007 , C12Y402/0202 , Y02A40/22 , Y02P60/21
Abstract: Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided. Plant seeds coated with free enzymes or recombinant microorganisms that overexpress enzymes are also provided. Compositions comprising a fertilizer and an enzyme or a recombinant microorganism that overexpresses an enzyme are provided. Modified enzymes having ACC deaminase activity, recombinant microorganisms expressing the modified enzymes, plant seeds treated with the modified enzymes or recombinant microorganisms, and methods for stimulating plant growth and/or promoting plant health using the modified enzymes or recombinant microorganisms are also provided.
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28.发明公开公开(公告)号：US20230322642A1
公开(公告)日：2023-10-12
申请号：US18302458
申请日：2023-04-18
Applicant: Spogen Biotech Inc.
Inventor： Brian M. Thompson , Jorg Augustin
IPC: C05F11/08 , C05B15/00 , C12N9/78 , C05G3/60 , A01N63/50 , C05F17/20 , C05C9/00 , C07K14/415 , C12N1/20 , C12N15/82
CPC classification number: C05F11/08 , C05B15/00 , C12N9/78 , C12Y305/99007 , C12Y302/01 , C12Y402/0202 , C05G3/60 , A01N63/50 , C05F17/20 , C05C9/00 , C07K14/415 , C12N1/20 , C12N15/8237 , C12N15/8249 , C12N15/8279 , Y02A40/22 , Y02P60/21
Abstract: Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided. Plant seeds coated with free enzymes or recombinant microorganisms that overexpress enzymes are also provided. Compositions comprising a fertilizer and an enzyme or a recombinant microorganism that overexpresses an enzyme are provided. Modified enzymes having ACC deaminase activity, recombinant microorganisms expressing the modified enzymes, plant seeds treated with the modified enzymes or recombinant microorganisms, and methods for stimulating plant growth and/or promoting plant health using the modified enzymes or recombinant microorganisms are also provided.
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公开(公告)号：US20220169999A1
公开(公告)日：2022-06-02
申请号：US17439990
申请日：2020-03-18
Applicant: Bayer CropScience LP , Spogen Biotech Inc.
Inventor： Jörg AUGUSTIN , Damian CURTIS , Elizabeth M. HENRY , Sara K. HOTTON , Anne LAMSA , Lakshmi Praba MANAVALAN , Varghese P. THOMAS , Brian THOMPSON
Abstract: The present invention relates to a fusion protein having a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member and a pectinase enzyme, wherein the pectinase is a pectate lyase from Bacillus spp. having any of SEQ ID NOs: 213-217 and 222-226 or a polygalaturonase from Aspergillus niger or certain Bacillus species that can have any of SEQ ID NOs: 210-212, 218-221, and 227. The present invention also provides a recombinant Bacillus cereus family member that expresses such fusion protein and exosporium fragments derived from such recombinant Bacillus cereus family member. Methods of using such recombinant Bacillus cereus family members or exosporium fragments derived therefrom for plant growth promotion are also provided.
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公开(公告)号：US20220151240A1
公开(公告)日：2022-05-19
申请号：US17356958
申请日：2021-06-24
Applicant: Bayer CropScience LP , Spogen Biotech Inc.
Inventor： Damian CURTIS , Brian THOMPSON
Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.
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