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    Odor Inhibiting Water-Absorbing Composites
    21.
    发明申请
    Odor Inhibiting Water-Absorbing Composites 有权
    气味抑制吸水复合材料

    公开(公告)号：US20110182845A1

    公开(公告)日：2011-07-28

    申请号：US13011507

    申请日：2011-01-21

    Applicant: Volker Braig ,  Thomas Daniel

    Inventor： Volker Braig ,  Thomas Daniel

    IPC: A61F13/15 ,  A61L101/50

    CPC classification number: A61L9/014 ,  Y10T442/2475 ,  Y10T442/2484 ,  Y10T442/277

    Abstract: The present invention relates to a process for producing odor-inhibiting water-absorbing composites comprising water-absorbing polymer particles and fibers, wherein the fibers are premixed with at least one metal peroxide, metal hyperoxide or metal ozonide.

    Abstract translation: 本发明涉及一种生产含吸水性聚合物颗粒和纤维的气味抑制吸水复合材料的方法，其中纤维与至少一种金属过氧化物，金属超氧化物或金属臭氧化物预混合。

    Unitizing Label and Handle for Multiple Packages
    22.
    发明申请
    Unitizing Label and Handle for Multiple Packages 审中-公开
    整合多个包的标签和句柄

    公开(公告)号：US20110147239A1

    公开(公告)日：2011-06-23

    申请号：US12643808

    申请日：2009-12-21

    Applicant: Thomas Daniel Arkins ,  Robert Sosnowski

    Inventor： Thomas Daniel Arkins ,  Robert Sosnowski

    IPC: B65D71/00 ,  B65D77/00 ,  G09F3/00

    CPC classification number: G09F3/10 ,  B65D69/00 ,  B65D75/56 ,  G09F3/0288 ,  Y10T29/49826

    Abstract: A unitizing label and handle for multiple packages bundles two or more adjacent packages, which may contain wet wipes for consumer use. A label is at least partially affixed to the two or more adjacent packages in order to retain them, the label adapted for separating at locations between each adjacent pair of the two or more adjacent packages to facilitate removal of a package. The label may also have a handle portion at least partially separable from the label such that the handle in a first position is generally parallel with the label such that it has a low profile, and in a second separated position the handle allows a user to grasp the label and carry the two or more adjacent packages.

    Abstract translation: 多个包装的组合标签和手柄捆绑两个或更多个相邻的包装，其可以包含用于消费者使用的湿巾。 标签至少部分地固定到两个或更多个相邻的包装上，以便保持它们，该标签适于在两个或更多个相邻包装的每对相邻的包装之间的位置处分离以便于去除包装。 标签还可以具有至少部分地与标签分离的手柄部分，使得处于第一位置的手柄通常与标签平行，使得其具有低轮廓，并且在第二分离位置，手柄允许使用者抓住 标签并携带两个或更多个相邻的包装。

    Production of a Water-Absorbing Resin to Which a Particulate Additive is Admixed
    25.
    发明申请
    Production of a Water-Absorbing Resin to Which a Particulate Additive is Admixed 失效
    混合颗粒添加剂的吸水树脂的生产

    公开(公告)号：US20100324212A1

    公开(公告)日：2010-12-23

    申请号：US12861338

    申请日：2010-08-23

    Applicant: Uwe Stueven ,  Rüdiger Funk ,  Matthias Weismantel ,  Thomas Daniel ,  Annemarie Hillebrecht ,  Dominicus van Esbroeck ,  Karl J. Possemiers

    Inventor： Uwe Stueven ,  Rüdiger Funk ,  Matthias Weismantel ,  Thomas Daniel ,  Annemarie Hillebrecht ,  Dominicus van Esbroeck ,  Karl J. Possemiers

    IPC: C08K3/34

    CPC classification number: C08F2/44 ,  C08F220/06 ,  C08F222/1006

    Abstract: The invention relates to a process for producing a water-absorbing resin by polymerization of a reaction mixture comprising at least one hydrophilic monomer and, if appropriate, at least one crosslinker in a reactor, which comprises admixing the reaction mixture with at least one first portion of a particulate additive before the reaction mixture has reached a residence time of 40% of the overall residence time in the reactor and with at least one second portion of a particulate additive when the reaction mixture has reached a residence time of 45% or more of the overall residence time in the reactor, the additive being selected from water-absorbing resin powders, fillers and mixtures thereof, the total solids content of monomer and additive being in the range from 30% to 60% by weight, the amount of additive being in the range from 5% to 50% by weight, based on the monomers, and the weight ratio of the first portion to the second portion of the additive being in the range from 10:1 to 1:5. The resin powder is recycled fine-sized material for example. Not only the residual monomer content, specifically the residual crosslinker content, but also the level of extractables in the water-absorbing resin are reduced by the method of addition described. A high fraction of additives can be incorporated without the properties of the water-absorbing resin obtained being adversely affected. The additives enter a sufficiently firm bond with the resin, so that no excessive dusting occurs on exposure to mechanical stress.

    Abstract translation: 本发明涉及通过聚合包含至少一种亲水单体和如果合适的反应器中至少一种交联剂的反应混合物来生产吸水树脂的方法，其包括将反应混合物与至少一个第一部分 的反应混合物在反应混合物的停留时间达到总反应器停留时间的40％的停留时间和至少一个第二部分的颗粒状添加剂之前，当反应混合物达到45％或更多的停留时间时， 在反应器中的总停留时间，添加剂选自吸水树脂粉末，填料及其混合物，单体和添加剂的总固体含量在30重量％至60重量％的范围内，添加剂的量为 基于单体的5重量％至50重量％的范围，并且添加剂的第一部分与第二部分的重量比在10:1至 1：5。 树脂粉末是例如再循环的精细尺寸的材料。 通过所述的添加方法，不仅残留单体含量，特别是残留交联剂含量，而且吸水性树脂中的可萃取物的含量都降低。 可以并入高分数的添加剂，而不会对获得的吸水性树脂的性能产生不良影响。 添加剂与树脂进行足够牢固的粘合，使得在暴露于机械应力时不会发生过度的除尘。

    N-[(3,5-DICHLOROPHENYL)METHYL]-2-(4-METHYL-1-PIPERAZINYL)-2-(1-NAPHTHALENYL)ETHANAMIDE AS GHRELIN RECEPTOR MODULATOR
    26.
    发明申请
    N-[(3,5-DICHLOROPHENYL)METHYL]-2-(4-METHYL-1-PIPERAZINYL)-2-(1-NAPHTHALENYL)ETHANAMIDE AS GHRELIN RECEPTOR MODULATOR 审中-公开
    N - [（3,5-二氯苯基）甲基] -2-（4-甲基-1-哌嗪基）-2-（1-萘甲酰）乙酰胺作为GHRELIN受体调节剂

    公开(公告)号：US20100267734A1

    公开(公告)日：2010-10-21

    申请号：US12602834

    申请日：2008-06-05

    Applicant: Thomas Daniel Heightman

    Inventor： Thomas Daniel Heightman

    IPC: A61K31/495 ,  C07D241/04 ,  A61P3/00

    CPC classification number: C07D295/15

    Abstract: The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt or solvate thereof, processes for their preparation, intermediates useable in these processes, pharmaceutical compositions containing them and their use in therapy, for example as modulators of the growth hormone secretagogue receptor (also referred to as the ghrelin receptor or GHSR1a receptor) and/or for the treatment and/or prophylaxis of a disorder mediated by the ghrelin receptor.

    Abstract translation: 本发明涉及新的式（I）化合物或其药学上可接受的盐或溶剂化物，其制备方法，可用于这些方法的中间体，含有它们的药物组合物及其在治疗中的用途，例如作为生长激素的调节剂 促分泌素受体（也称为生长素释放肽受体或GHSR1a受体）和/或用于治疗和/或预防由生长素释放肽受体介导的病症。

    GRANULATES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL PRODUCTS CONTAINING THEM
    27.
    发明申请
    GRANULATES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL PRODUCTS CONTAINING THEM 审中-公开
    颗粒，制备它们的方法和含有它们的药用产品

    公开(公告)号：US20100209495A1

    公开(公告)日：2010-08-19

    申请号：US12560668

    申请日：2009-09-16

    Applicant: Boyong LI ,  Thomas Daniel Reynolds

    Inventor： Boyong LI ,  Thomas Daniel Reynolds

    IPC: A61K31/165 ,  A61K9/48 ,  A61K9/14 ,  A61K9/20 ,  A61P35/00

    CPC classification number: A61K9/2027 ,  A61K9/2018 ,  A61K9/2059 ,  A61K31/277

    Abstract: A granulate for use in a pharmaceutical composition and a pharmaceutical composition manufacture using the granulate, where the granule comprises an active pharmaceutical ingredient (API) having a poor water solubility (i.e., less than about 1 mg/mL) which is intimately associated with at least one pharmaceutically acceptable hydrophilic polymer. The granule optionally contains one or more pharmaceutically acceptable excipients, such as disintegrants, wetting agents, diluents, binders, lubricants, glidants, coloring agents and flavoring agents. The invention also relates to a process for preparing the pharmaceutical granulate and pharmaceutical compositions containing the granulate.

    Abstract translation: 用于药物组合物的颗粒和使用该颗粒的药物组合物制造，其中颗粒包含具有差的水溶性（即小于约1mg / mL）的活性药物成分（API），其与 至少一种药学上可接受的亲水性聚合物。 颗粒任选地含有一种或多种药学上可接受的赋形剂，例如崩解剂，润湿剂，稀释剂，粘合剂，润滑剂，助流剂，着色剂和调味剂。 本发明还涉及制备含有颗粒的药物颗粒和药物组合物的方法。

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