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    Analyte sensors and methods of using same
    21.
    发明授权
    Analyte sensors and methods of using same 有权

    公开(公告)号：US10859525B2

    公开(公告)日：2020-12-08

    申请号：US15964217

    申请日：2018-04-27

    Applicant: Abbott Diabetes Care Inc.

    Inventor： Benjamin J. Feldman ,  Zenghe Liu ,  Tianmei Ouyang ,  Suyue Qian

    IPC: G01N27/327 ,  C12Q1/00

    Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.

    Systems and Methods for Improved In Vivo Analyte Sensor Function
    22.
    发明申请
    Systems and Methods for Improved In Vivo Analyte Sensor Function 审中-公开

    公开(公告)号：US20200205706A1

    公开(公告)日：2020-07-02

    申请号：US16815791

    申请日：2020-03-11

    Applicant: Abbott Diabetes Care Inc.

    Inventor： Benjamin J. Feldman ,  Zenghe Liu

    IPC: A61B5/145 ,  A61B5/1486

    Abstract: An analyte sensor comprising: an insertion tip configured for insertion below a tissue of a user, the insertion tip comprising: a working electrode comprising a sensing layer disposed thereon and a membrane layer disposed at least partially over the sensing layer; a substrate; and a counter electrode. Wherein a polymer layer comprising at least an immunosuppressant is disposed on an exterior surface of the working electrode, the substrate, or the counter electrode, the polymer layer being separate from the sensing layer and the membrane layer.

    SELF-POWERED ANALYTE SENSOR
    23.
    发明申请
    SELF-POWERED ANALYTE SENSOR 审中-公开

    公开(公告)号：US20180296139A1

    公开(公告)日：2018-10-18

    申请号：US16015882

    申请日：2018-06-22

    Applicant: ABBOTT DIABETES CARE INC.

    Inventor： Benjamin J. Feldman ,  Zenghe Liu ,  Tianmei Ouyang

    IPC: A61B5/1486 ,  G01N27/327 ,  C12Q1/00 ,  A61B5/00 ,  A61B5/145 ,  A61B90/98 ,  G01N27/403

    Abstract: Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

    Analyte sensors and methods of using same
    28.
    发明授权
    Analyte sensors and methods of using same 有权
    分析物传感器及其使用方法

    公开(公告)号：US09535027B2

    公开(公告)日：2017-01-03

    申请号：US13949996

    申请日：2013-07-24

    Applicant: Abbott Diabetes Care Inc.

    Inventor： Benjamin J. Feldman ,  Zenghe Liu ,  Tianmei Ouyang ,  Suyue Qian

    IPC: G01N27/327

    CPC classification number: G01N27/3272 ,  C12Q1/004 ,  C12Q1/006 ,  G01N27/327

    Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.

    Abstract translation: 提供了用于确定样品流体中分析物的浓度的传感器。 在某些实施例中，传感器包括导电颗粒并且表现出改进的一个或多个感测化学组分分布均匀性，增加的有效工作电极表面积，和/或减少干扰组分进入传感器的样品室。 还提供了使用和制造传感器的方法。

    Continuous potassium sensors and methods of use thereof
    30.
    发明授权
    Continuous potassium sensors and methods of use thereof 有权

    公开(公告)号：US12290355B2

    公开(公告)日：2025-05-06

    申请号：US17561383

    申请日：2021-12-23

    Applicant: Abbott Diabetes Care Inc.

    Inventor： Zenghe Liu ,  Barry S. Kreutz ,  Yagya Raj Ojha ,  Benjamin J. Feldman ,  Thomas P Leary ,  Tram Nguyen

    IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486

    Abstract: The present disclosure provides an analyte sensor for use in detecting potassium. In certain embodiments, an analyte sensor of the present disclosure includes at least two asparagine-responsive active areas, where each asparagine-responsive active area includes an asparaginase that exhibits a particular potassium dependency. In certain embodiments, an analyte sensor of the present disclosure includes at least two aspartate-responsive active areas, where each aspartate-responsive active area includes an aspartate oxidase that exhibits a particular potassium dependency. The present disclosure further provides methods for monitoring potassium levels, e.g., in vivo potassium levels, using the disclosed analyte sensors.

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