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公开(公告)号：US20220257491A1
公开(公告)日：2022-08-18
申请号：US17673480
申请日：2022-02-16
Inventor： Wim TEUGHELS , Tim VERSPECHT , Kristel BERNAERTS , Marc QUIRYNEN , Nico BOON , Carlo DAEP , James MASTERS
Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-mannose, N-acetyl-D-mannosamine and mixtures thereof; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.
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公开(公告)号：US20220071867A1
公开(公告)日：2022-03-10
申请号：US17309858
申请日：2019-12-17
Applicant: Colgate-Palmolive Company
Inventor： Camille ZENOBIA , Carlo DAEP , Dandan CHEN , Harsh Mahendra TRIVEDI , James MASTERS
Abstract: Methods of increasing proteins that reduce signals associated with neutrophil recruitment and reducing proteins that induce neutrophil recruitment within an individuals gingival crevice are disclosed. The methods comprise applying to the individuals oral cavity in an amount effective to increase proteins that reduce signals associated with neutrophil recruitment and reduce proteins that induce neutrophil recruitment within an individuals gingival crevice, an oral care composition comprising: zinc phosphate, stannous fluoride and optionally, an organic acid buffer system.
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公开(公告)号：US20210404005A1
公开(公告)日：2021-12-30
申请号：US17471876
申请日：2021-09-10
Inventor： David T.W. WONG , Karolina Elzbieta KACZOR-URBANOWICZ , Harsh Mahendra TRIVEDI , James MASTERS
IPC: C12Q1/6883
Abstract: Described herein are methods used for the detection of gingivitis and the monitoring of gingivitis in a subject.
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24.发明申请公开(公告)号：US20200246242A1
公开(公告)日：2020-08-06
申请号：US16758434
申请日：2017-12-19
Applicant: Colgate-Palmolive Company
Inventor： Shujiang CHENG , Zeenat NABI , Laurence DU-THUMM , Qiang WU , Jane ONG , Halyna SIOMYK , Harsh Mahendra TRIVEDI , James MASTERS , Chi-Yuan CHENG , Donghui WU
Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.
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公开(公告)号：US20200236945A1
公开(公告)日：2020-07-30
申请号：US16846770
申请日：2020-04-13
Inventor： Carl MYERS , Carlo DAEP , Lynette ZAIDEL , James MASTERS , Russell COMPOSTO , Hyun-Su LEE
IPC: A01N47/44 , C11D3/48 , A61Q17/00 , A61K8/91 , A61K31/785 , C11D3/37 , C09D139/00 , C09D5/14 , C08F126/02 , C08F8/30 , A61Q11/00 , A61K8/81 , A01N25/08
Abstract: Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
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Patent Agency Ranking
公开(公告)号：US20200206115A1
公开(公告)日：2020-07-02
申请号：US16798492
申请日：2020-02-24
Applicant: Colgate-Palmolive Company
Inventor： Zhiqiang LIU , Long PAN , Shaotang YUAN , Jairajh MATTAI , James MASTERS
Abstract: Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
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公开(公告)号：US20180333349A1
公开(公告)日：2018-11-22
申请号：US15597676
申请日：2017-05-17
Applicant: Colgate-Palmolive Company
Inventor： Shamim Ansari , Harsh Mahendra TRIVEDI , James MASTERS
Abstract: Disclosed herein are oral care compositions comprising hemp seed oil and caprylyl glycol. In certain embodiments, the oral care composition optionally further comprises one or more ingredients selected from hyaluronic acid and aloe vera. Methods of making and using the compositions are also provided.
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公开(公告)号：US20240271216A1
公开(公告)日：2024-08-15
申请号：US18636097
申请日：2024-04-15
Inventor： David T.W. WONG , Karolina Elzbieta KACZOR-URBANOWICZ , Harsh Mehendra TRIVEDI , James MASTERS
IPC: C12Q1/6883
CPC classification number: C12Q1/6883 , C12Q2600/106 , C12Q2600/158 , C12Q2600/178
Abstract: Described herein are methods used for the detection of gingivitis and the monitoring of gingivitis in a subject.
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公开(公告)号：US20240050344A1
公开(公告)日：2024-02-15
申请号：US18549085
申请日：2021-03-11
Applicant: Colgate-Palmolive Company
Inventor： Ying YANG , Shaopeng XU , Guofeng XU , Harsh Mahendra TRIVEDI , James MASTERS , Dandan CHEN , Betty WON
CPC classification number: A61K8/44 , A61K8/27 , A61Q11/00 , A61K8/21 , A61K2800/92
Abstract: Methods of increasing sIgA levels in an individual's oral cavity are disclosed. The methods comprise applying effective amounts of zinc oxide, zinc citrate, and arginine Methods of increasing the concentration of sIgA in the individual's mucosa pellicle in the oral cavity are disclosed. Methods of increasing phagocytotic activity of phagocytotic cells in the individual's oral cavity are also disclosed. In addition, methods of increasing levels of β-Defensin 1 in the individual's oral cavity are disclosed.
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公开(公告)号：US20220357268A1
公开(公告)日：2022-11-10
申请号：US17250473
申请日：2020-10-29
Inventor： Carlo Daep , Deon HINES , Harsh Mahendra TRIVEDI , James MASTERS , LaTonya KILPATRICK-LIVERMAN , Luciana RINAUDI MARRON , Lynette ZAIDEL , Alexander H. RICKARD , Derek S. SAMARIAN , Gregory KRUSE
Abstract: A system for testing biological samples includes a frame having first and second sides and an aperture extending through the frame from the first side to the second side. First and second covers are attached to the first and second sides of the frame to form a well bounded by the frame, the first cover, and the second cover. An electromagnetic imaging device is used to image the biological sample through the first cover. A method is also conceived, wherein a first fluid is supplied to the well, the first fluid including live cells. A biofilm is grown from the live cells. A second fluid is supplied to the well and the biofilm is imaged using the electromagnetic imaging device.
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