公开(公告)号：US20210128932A1

公开(公告)日：2021-05-06

申请号：US16974000

申请日：2019-06-17

Applicant: Emblation Limited

Inventor： Eamon McErlean ,  Gary Beale

IPC: A61N5/02 ,  A61B5/318 ,  A61B5/0205 ,  A61B5/369 ,  A61N1/36 ,  A61N5/10 ,  G01N33/50

Abstract: An electromagnetic energy delivery system is configured to deliver energy in specific timing arrangements to improve an immune response. The electromagnetic energy delivery system may comprise a controlled electromagnetic energy source and an electromagnetic energy applicator, wherein the controlled electromagnetic energy source is configured to emit electromagnetic energy according to the specific timing arrangements as defined by a treatment profile which is configured so that the emitted electromagnetic energy stimulates and/or inhibits an immune response in a host when the emitted electromagnetic energy is delivered to the host via the electromagnetic energy applicator. A method of electromagnetic energy delivery,comprises delivering energy in specific timing arrangements to improve an immune response.

公开(公告)号：US20190298447A1

公开(公告)日：2019-10-03

申请号：US16447663

申请日：2019-06-20

Applicant: Emblation Limited

Inventor： Gary Beale ,  Eamon McErlean

IPC: A61B18/18 ,  H05B6/70 ,  H05B6/72 ,  B05D5/00 ,  B29C45/00

Abstract: A method of forming a microwave applicator comprising forming a body comprising dielectric material so that there is a void in the dielectric material, and depositing conductive material in the void to form a feed for coupling energy into the dielectric material.

公开(公告)号：US20190274758A1

公开(公告)日：2019-09-12

申请号：US16277146

申请日：2019-02-15

Applicant: Emblation Limited

Inventor： Gary Beale ,  Eamon McErlean ,  Matthew Kidd

IPC: A61B18/18 ,  A61K9/00

Abstract: Described herein are methods and apparatus for treating or preventing epidermal dysplasias, including, for example, dysplastic epidermal lesions and dermatological pre-cancerous disease.

公开(公告)号：US20240173561A1

公开(公告)日：2024-05-30

申请号：US18562654

申请日：2022-05-20

Applicant: Emblation Limited

Inventor： Gary Beale ,  Eamon McErlean ,  Shailesh Joshi ,  Matthew Kidd

IPC: A61N5/02 ,  C12N13/00

CPC classification number: A61N5/025 ,  C12N13/00

Abstract: The disclosure is based on the finding that microwave energy may be used to modulate, for example up- or down-regulate the expression of certain genes. For example, where a disease or condition is associated with the aberrant expression of a particular gene or genes, microwave energy may be used to modulate the expression of those genes, thereby resolving and/or improving one or more of the symptoms of the disease or condition. Disclosed is a microwave system or microwave-generating apparatus, for use in a method of modulating the expression of one or more genes. Also disclosed are uses of microwave energy for modulating the expression of one or more genes in tissues, tissue samples and biopsies.

公开(公告)号：US11980769B2

公开(公告)日：2024-05-14

申请号：US15938238

申请日：2018-03-28

Applicant: Emblation Limited

Inventor： Eamon McErlean ,  Gary Beale ,  Matthew Donald Kidd

IPC: A61N5/02 ,  A61F2/82 ,  A61K41/00 ,  A61N5/04 ,  A61P9/10 ,  A61B18/18 ,  A61M25/10

CPC classification number: A61N5/025 ,  A61F2/82 ,  A61K41/0052 ,  A61N5/045 ,  A61P9/10 ,  A61B2018/1861 ,  A61M25/10

Abstract: Heat and heat based treatments that may be used to modulate, inhibit and/or prevent one or more of the processes that contribute to certain vascular and/or arterial complications.

公开(公告)号：US20230255686A1

公开(公告)日：2023-08-17

申请号：US18017157

申请日：2021-07-19

Applicant: Emblation Limited

Inventor： Eamon McErlean ,  Gary Beale

IPC: A61B18/18 ,  H03F3/19 ,  H03G3/00

CPC classification number: A61B18/1815 ,  H03F3/19 ,  H03G3/004 ,  A61B2018/00702 ,  H03G2201/103

Abstract: An electromagnetic energy delivery apparatus comprises: an amplifier; an amplifier input configured to provide to the amplifier a signal to be amplified; bias circuitry configured to provide a bias signal to the amplifier, wherein amplifying of the input signal by the amplifier is dependent on the bias signal provided by the bias circuitry; an amplifier output configured to provide an output signal comprising an amplified version of the input signal, for providing energy delivery to a radiating element to produce electromagnetic radiation; and a controller configured to control operation of the bias circuitry to provide a time- varying bias signal thereby to provide a desired time variation of the output signal.

公开(公告)号：US20230129737A1

公开(公告)日：2023-04-27

申请号：US17912465

申请日：2021-03-18

Applicant: Emblation Limited

Inventor： Gary Beale ,  Eamon McErlean

IPC: A61L9/18

Abstract: Apparatus for electromagnetic treatment of at least one pathogen in air or other gas, comprises a waveguide structure including a treatment region within the waveguide structure, wherein the treatment region is configured to receive the air or other gas that contains the at least one pathogen, means for providing electromagnetic radiation to the treatment region, and at least one structure permeable to the air or other gas and that is configured to at least partially confine the electromagnetic radiation, wherein the at least one permeable structure forms at least one boundary of the treatment region.

公开(公告)号：US10335231B2

公开(公告)日：2019-07-02

申请号：US14364404

申请日：2012-12-14

Applicant: Emblation Limited

Inventor： Gary Beale ,  Eamon McErlean

IPC: A61B18/18 ,  H05B6/70 ,  H05B6/72 ,  B05D5/00 ,  B29C45/00 ,  B29L31/34

Abstract: A method of forming a microwave applicator comprising forming a body comprising dielectric material so that there is a void in the dielectric material, and depositing conductive material in the void to form a feed for coupling energy into the dielectric material.

公开(公告)号：US20190175271A1

公开(公告)日：2019-06-13

申请号：US16326834

申请日：2017-08-25

Applicant: Emblation Limited

Inventor： Gary Beale ,  Eamon McErlean ,  Matthew Donal Kidd

IPC: A61B18/18 ,  A61N5/04

Abstract: A microwave system comprises a microwave generator and a microwave cable apparatus comprising a coaxial cable having a diagonally-angled end surface, wherein the microwave generator is configured to provide microwave energy to the cable apparatus at a frequency that provides directional radiation of microwave energy having a desired directionality from the diagonally-angled end surface.

公开(公告)号：US09700379B2

公开(公告)日：2017-07-11

申请号：US14397784

申请日：2013-04-30

Applicant: Emblation Limited

Inventor： Eamon McErlean ,  Gary Beale

IPC: G01R31/07 ,  A61B19/00 ,  A61B90/00 ,  A61B90/90 ,  A61B18/14 ,  A61B18/18 ,  A61B17/00

CPC classification number: A61B90/00 ,  A61B18/14 ,  A61B18/1815 ,  A61B90/90 ,  A61B2017/00482 ,  A61B2090/0803 ,  A61B2090/0814 ,  G01R31/07

Abstract: An apparatus for determining a status of a medical device component is disclosed. The apparatus includes at least one fusible component to indicate whether the medical device component has been used, and at least one reference component having at least one reference property that is representative of the presence, identity or type of the medical device component. The reference component is non-fusible under ordinary operating conditions.