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公开(公告)号:US10393662B2
公开(公告)日:2019-08-27
申请号:US15646041
申请日:2017-07-10
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY L.P.
Inventor: Zhang-Lin Zhou , Lihua Zhao , Steven J. Barcelo , Zhiyong Li
Abstract: A method for forming a surface-enhanced fluorescence spectroscopy (SEFS) apparatus may include depositing a plurality of surface-enhanced spectroscopy (SES) elements onto respective tips of a plurality of nano-fingers, wherein the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of a group of adjacent nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to trap fluorescent probe molecules that are to bind with target molecules when the nano-fingers are partially collapsed.
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公开(公告)号:US10026894B2
公开(公告)日:2018-07-17
申请号:US15512141
申请日:2014-09-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Ning Ge , Jianhua Yang , Zhiyong Li , Minxian Zhang , Katy Samuels
Abstract: An example memristor includes a first conductive layer, a switching layer, and a second conductive layer. The first conductive layer may include a first conductive material and a second conductive material. The second conductive material may have a higher diffusivity than the first conductive material. The switching layer may be coupled to the first conductive layer and may include a first oxide having the first conductive material and a second oxide having the second conductive material. The second conductive layer may be coupled to the switching layer.
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公开(公告)号:US09879299B2
公开(公告)日:2018-01-30
申请号:US14475532
申请日:2014-09-02
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Mineo Yamakawa , Zhiyong Li
IPC: C12Q3/00 , C12Q1/02 , C12M1/34 , G01N33/483
CPC classification number: C12Q1/02 , C12M41/36 , C12M41/46 , C12Q3/00 , G01N33/4833
Abstract: The present disclosure is drawn to a device for monitoring and controlling live cells and associated methods. In an example, the device can include a plurality of elongated nanostructures affixed to a substrate. The elongated nanostructures can each have an attachment end and a free end opposite the attachment end. The free end includes a metal and the attachment end is affixed to the substrate. The device can further include a functionalization layer that is coated on the free end of at least a portion of the plurality of elongated nanostructures. The functionalization layer can be formulated to retain live cells, and the device can be configured to be used in conjunction with a detector, such as a Raman spectrometer, in order to monitor growth of live cells.
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公开(公告)号:US09778198B2
公开(公告)日:2017-10-03
申请号:US15247693
申请日:2016-08-25
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Steven Barcelo , Zhiyong Li , Alexandre M. Bratkovski , Ansoon Kim
CPC classification number: G01N21/658 , B82Y15/00 , G01N2201/06113 , Y10S977/954
Abstract: An apparatus for performing a sensing application may a substrate having a plurality of nano-fingers positioned to receive the dispensed solution , first and second reservoirs, first and second dispensers to dispense first and second solutions from the first and second reservoirs onto first and second subsets of the plurality of nano-fingers. The plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus may include an illumination source to illuminate the first and second solutions and an analyte introduced around the plurality of nano-fingers, wherein light is to be emitted from the analyte in response to being illuminated. The apparatus may include a detector to detect the light emitted from the analyte.
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公开(公告)号:US09664621B2
公开(公告)日:2017-05-30
申请号:US14763510
申请日:2013-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Gary Gibson , Huei Pei Kuo , Steven J. Barcelo , Zhiyong Li
CPC classification number: G01N21/658 , G01J3/4412 , G01N21/21 , G01N2201/06113 , G01N2201/0683
Abstract: Polarization selective surface enhanced Raman spectroscopy (SERS) includes a plurality of nanofingers arranged as a SERS multimer to exhibit a polarization-dependent plasmonic mode and one or both of a stimulus source and a Raman detector. The stimulus source is to illuminate the SERS multimer with a stimulus signal and the Raman detector is to detect a Raman scattering signal emitted by an analyte in a vicinity of the SERS multimer. One or both of the Raman scattering signal has a polarization state dictated by or associated with the polarization-dependent plasmonic mode and the stimulus signal has a polarization state corresponding to the polarization-dependent plasmonic mode.
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公开(公告)号:US20150355097A1
公开(公告)日:2015-12-10
申请号:US14763491
申请日:2013-01-25
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Zhang-Lin Zhou , Zhiyong Li , Steven J. Barcelo
IPC: G01N21/65
CPC classification number: B82Y15/00 , G01N21/554 , G01N21/648 , G01N21/658 , G01N2021/651
Abstract: The present disclosure is drawn to chemical sensing devices and associated methods. In one example, a chemical sensing device can include a substrate; an elongated nanostructure having an attachment end and a free end opposite the attachment end, the attachment end affixed to the substrate and the free end including a metal; and a metal oxide coating applied to the elongated nanostructure. In one example, a functional group can be attached to the coating via a covalent bond.
Abstract translation: 本公开涉及化学感测装置和相关方法。 在一个示例中,化学感测装置可以包括基底; 细长的纳米结构,其具有附接端和与所述附接端相对的自由端,所述附接端固定到所述基底并且所述自由端包括金属; 以及施加到细长纳米结构的金属氧化物涂层。 在一个实例中,可以通过共价键将官能团连接到涂层上。
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公开(公告)号:US20150114927A1
公开(公告)日:2015-04-30
申请号:US14169375
申请日:2014-01-31
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Jianhua Yang , Ning Ge , Zhiyong Li , Minxian Max Zhang
IPC: B41J2/16
CPC classification number: B41J2/14072 , B41J2/04541 , B41J2/0458 , B41J2/14016 , B41J2/14129 , B41J2/1601 , B41J2/1607 , B41J2/1626 , B41J2/1631 , B41J2202/13 , H01L21/02565 , H01L27/24 , H01L27/2463 , H01L45/00 , H01L45/04 , H01L45/08 , H01L45/145 , H01L45/146 , H01L45/147 , H01L45/1633 , H01L45/1675
Abstract: Forming memristors on imaging devices can include forming a printhead body comprising a first conductive material, forming a memory on the printhead body by performing an oxidation process to form a switching oxide material on the first conductive material, and forming a second conductive material on the switching oxide material.
Abstract translation: 在成像装置上形成忆阻器可以包括形成包括第一导电材料的打印头主体,通过执行氧化处理在第一导电材料上形成切换氧化物材料,在开关上形成第二导电材料,在打印头主体上形成存储器 氧化物。
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公开(公告)号:US08810780B1
公开(公告)日:2014-08-19
申请号:US13755801
申请日:2013-01-31
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Steven J Barcelo , Zhiyong Li , Gary Gibson , Mineo Yamakawa , Ansoon Kim
Abstract: A strain gauge or other device may include a deformable medium and discrete plasmon supporting structures arranged to create one or more plasmon resonances that change with deformation of the medium and provide the device with an optical characteristic that indicates the deformation of the medium.
Abstract translation: 应变计或其它装置可以包括可变形介质和离散的等离子体支撑结构,其布置成产生一个或多个等离子体共振,其随着介质的变形而变化,并为该装置提供指示介质变形的光学特性。
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29.
公开(公告)号:US20140212867A1
公开(公告)日:2014-07-31
申请号:US13754860
申请日:2013-01-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Mineo Yamakawa , Zhiyong Li
CPC classification number: C12Q1/02 , C12M41/36 , C12M41/46 , C12Q3/00 , G01N33/4833
Abstract: The present disclosure is drawn to a device for monitoring and controlling live cells and associated methods. In an example, the device can include a plurality of elongated nanostructures affixed to a substrate. The elongated nanostructures can each have an attachment end and a free end opposite the attachment end. The free end includes a metal and the attachment end is affixed to the substrate. The device can further include a functionalization layer that is coated on the free end of at least a portion of the plurality of elongated nanostructures. The functionalization layer can be formulated to retain live cells, and the device can be configured to be used in conjunction with a detector, such as a Raman spectrometer, in order to monitor growth of live cells.
Abstract translation: 本公开涉及用于监测和控制活细胞和相关方法的装置。 在一个示例中,该装置可以包括固定到基底上的多个细长的纳米结构。 细长的纳米结构可以各自具有附接端和与附接端相对的自由端。 自由端包括金属,并且附接端固定到基底。 该装置还可以包括涂覆在多个细长纳米结构的至少一部分的自由端上的官能化层。 功能化层可以配制成保留活细胞,并且该装置可被配置为与诸如拉曼光谱仪的检测器结合使用,以便监测活细胞的生长。
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公开(公告)号:US10712278B2
公开(公告)日:2020-07-14
申请号:US15569764
申请日:2015-06-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Charles M. Santori , Ning Ge , Zhiyong Li , Steven Barcelo
Abstract: Provided in one example is an analyte detection package that includes a chamber, a surface-enhanced luminescence analyte stage within the chamber, and a lens integrated as part of the package to focus radiation onto the analyte stage.
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