公开(公告)号：US20070048240A1

公开(公告)日：2007-03-01

申请号：US11507845

申请日：2006-08-22

Applicant: Paul Slavashevich ,  John Carson ,  Albert Zofchak

Inventor： Paul Slavashevich ,  John Carson ,  Albert Zofchak

IPC: A61K8/89

CPC classification number: A61K8/042 ,  A61K8/895 ,  A61Q17/04 ,  A61Q19/00

Abstract: The present invention relates to the use of cross-linked silicone gel, in particular, a polymerization product of a polyorganohydrosiloxane, with the proposed INCI name (Dimethicone/polymethylalkyl siloxane copolymer), in cosmetic applications to provide unexpected characteristics related to formulations incorporating these silicone gels.

Abstract translation: 本发明涉及交联硅胶，特别是聚有机氢硅氧烷的聚合产物与所提出的INCI名称（聚二甲基硅氧烷/聚甲基烷基硅氧烷共聚物）在化妆品应用中的用途，以提供与掺入这些硅氧烷 凝胶。

公开(公告)号：US20050148636A1

公开(公告)日：2005-07-07

申请号：US11065914

申请日：2005-02-25

Applicant: John Carson ,  Ellen Codd ,  Philip Pitis

Inventor： John Carson ,  Ellen Codd ,  Philip Pitis

IPC: A61K31/4178 ,  A61K31/4439 ,  A61P1/06 ,  A61P1/08 ,  A61P1/12 ,  A61P1/14 ,  A61P3/10 ,  A61P5/00 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P13/00 ,  A61P17/02 ,  A61P17/04 ,  A61P19/02 ,  A61P19/08 ,  A61P21/00 ,  A61P21/02 ,  A61P25/00 ,  A61P25/02 ,  A61P25/04 ,  A61P25/06 ,  A61P25/08 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P27/02 ,  A61P27/06 ,  A61P27/16 ,  A61P29/00 ,  A61P31/18 ,  A61P35/00 ,  A61P43/00 ,  C07D401/06 ,  C07D403/06 ,  C07D409/14 ,  C07D43/02

CPC classification number: C07D401/06 ,  C07D403/06 ,  C07D409/14

Abstract: This invention is directed to aroyl pyrrole heteroaryl methanone and methanol compounds pharmaceutically useful as agents for treating or modulating a central nervous system disorder and methods for treating or modulating a central nervous system disorder.

Abstract translation: 本发明涉及可用作治疗或调节中枢神经系统疾病的药物的芳酰基吡咯杂芳基甲酮和甲醇化合物以及用于治疗或调节中枢神经系统疾病的方法。

公开(公告)号：US20050106193A1

公开(公告)日：2005-05-19

申请号：US10714772

申请日：2003-11-17

Applicant: Albert Zofchak ,  John Carson ,  Jebadiah Jorden

Inventor： Albert Zofchak ,  John Carson ,  Jebadiah Jorden

IPC: A61K8/45 ,  A61K8/86 ,  A61Q5/02 ,  A61Q19/00 ,  A61K7/06 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61Q5/02 ,  A61K8/86 ,  A61Q19/00

Abstract: The invention provides personal care products comprising fatty ethoxylated dimeric urethane compounds that enhance the viscosity of constituent water based surfactant systems. In compositions and methods of the invention, ethoxylated nonionic, urethane dimers increase the viscosity of water based surfactant systems and serve as thickeners. These thickeners produce clear solutions in combination with surfactants and can be made sufficiently water soluble to produce clear solutions in water. The thickeners are compatible with anionic, cationic, amphoteric and nonionic surfactants and are functional and stable over a wide pH range.

Abstract translation: 本发明提供包含脂肪乙氧基化二聚氨基甲酸酯化合物的个人护理产品，其增强组分水基表面活性剂体系的粘度。 在本发明的组合物和方法中，乙氧基化的非离子型氨基甲酸酯二聚体增加了水基表面活性剂体系的粘度并用作增稠剂。 这些增稠剂与表面活性剂组合产生澄清溶液，并且可以制成足够的水溶性以在水中产生澄清溶液。 增稠剂与阴离子，阳离子，两性和非离子表面活性剂相容，在宽pH范围内具有功能和稳定性。

公开(公告)号：US09822010B2

公开(公告)日：2017-11-21

申请号：US13011564

申请日：2011-01-21

Applicant: Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  John Carson ,  Martin S. Flacks

Inventor： Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  John Carson ,  Martin S. Flacks

IPC: B05D3/10 ,  C01B33/18 ,  C09C1/30 ,  A61K9/50

CPC classification number: C01B33/18 ,  A61K9/501 ,  C01P2004/03 ,  C01P2004/34 ,  C01P2004/52 ,  C09C1/30

Abstract: This invention relates to a method for emulsion templating hollow silica-based particles. The particles are suitable for containing one or more active ingredients or for containing other smaller particles which may include one or more active ingredients. The emulsion templated particles can be formed from two or more silanes. The emulsion templated particles can also be formed from a silane and a compound that attaches a polymer on the shell of the hollow silica-based particles.

公开(公告)号：US20120104638A1

公开(公告)日：2012-05-03

申请号：US13168703

申请日：2011-06-24

Applicant: Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  John Carson ,  Martin S. Flacks ,  Rachel Sullivan ,  Daniel H. Traynor

Inventor： Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  John Carson ,  Martin S. Flacks ,  Rachel Sullivan ,  Daniel H. Traynor

IPC: B01J13/14

CPC classification number: B01J13/18 ,  A61K8/0279 ,  A61K8/25 ,  A61K2800/10 ,  A61K2800/412 ,  A61K2800/623 ,  A61Q19/00 ,  B01J13/22 ,  C01B33/12 ,  C11D3/124 ,  C11D3/505 ,  C11D17/0034

Abstract: This invention relates to a method for forming hollow silica-based particles suitable for containing one or more active ingredients or for containing other smaller particles which may include one or more active ingredients. The emulsion templated particles can be formed from two or more silanes. The emulsion templated particles can also be formed from a silane and a compound that attaches a polymer on the shell of the hollow silica-based particles.

Abstract translation: 本发明涉及一种形成中空二氧化硅基颗粒的方法，该方法适于含有一种或多种活性成分或含有其它可包含一种或多种活性成分的较小颗粒。 乳液模板化颗粒可以由两种或更多种硅烷形成。 乳液模板化颗粒也可以由硅烷和将聚合物附着在中空二氧化硅基颗粒的壳上的化合物形成。

公开(公告)号：US20100322877A1

公开(公告)日：2010-12-23

申请号：US12734177

申请日：2008-10-21

Applicant: Albert A. Zofchak ,  John Carson ,  Nagi M. Awad ,  Rustico Payuno

Inventor： Albert A. Zofchak ,  John Carson ,  Nagi M. Awad ,  Rustico Payuno

IPC: A61K8/37 ,  A61Q17/04 ,  A61Q15/00 ,  A61Q9/02 ,  A61Q5/12 ,  C11D3/37 ,  A61Q5/02 ,  A61Q19/10 ,  A61Q13/00

CPC classification number: A61K8/37 ,  A61K8/042 ,  A61K8/891 ,  A61K2800/31 ,  A61K2800/48 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q17/04 ,  A61Q19/00

Abstract: The invention describes the unexpected solubility characteristics of a number of cosmetic esters when used as solvents during the crosslinking reaction of silicone polymers to make elastomers, their use as diluting media and the uses of these ester elastomer mixtures in cosmetic and personal care products.

Abstract translation: 本发明描述了当硅氧烷聚合物在制备弹性体的交联反应中用作溶剂时，许多化妆品酯的意想不到的溶解度特征，它们作为稀释介质的用途以及这些酯弹性体混合物在化妆品和个人护理产品中的用途。

公开(公告)号：US20070202072A1

公开(公告)日：2007-08-30

申请号：US10578974

申请日：2004-11-08

Applicant: Albert Zofchak ,  John Carson ,  Jebadiah Jorden

Inventor： Albert Zofchak ,  John Carson ,  Jebadiah Jorden

IPC: A61K8/45 ,  C07C271/24

CPC classification number: A61Q5/02 ,  A61K8/86 ,  A61Q19/00

Abstract: The invention provides personal care products comprising fatty ethoxylated dimeric urethane compounds that enhance the viscosity of constituent water based surfactant systems. In compositions and methods of the invention, ethoxylated nonionic, urethane dimers increase the viscosity of water based surfactant systems and serve as thickeners. These thickeners produce clear solutions in combination with surfactants and can be made sufficiently water soluble to produce clear solutions in water. The thickeners are compatible with anionic, cationic, amphoteric and nonionic surfactants and are functional and stable over a wide pH range.

Abstract translation: 本发明提供包含脂肪乙氧基化二聚氨基甲酸酯化合物的个人护理产品，其增强组分水基表面活性剂体系的粘度。 在本发明的组合物和方法中，乙氧基化非离子型氨基甲酸酯二聚体增加了水基表面活性剂体系的粘度并用作增稠剂。 这些增稠剂与表面活性剂组合产生澄清溶液，并且可以制成足够的水溶性以在水中产生澄清溶液。 增稠剂与阴离子，阳离子，两性和非离子表面活性剂相容，在宽pH范围内具有功能和稳定性。

公开(公告)号：US20050182108A1

公开(公告)日：2005-08-18

申请号：US10778980

申请日：2004-02-13

Applicant: John Carson ,  James McNally

Inventor： John Carson ,  James McNally

IPC: A61K31/16 ,  A61K31/40 ,  A61K31/44 ,  A61K31/495 ,  A61K31/537 ,  A61K31/54

CPC classification number: A61K31/4402 ,  A61K31/16 ,  A61K31/40 ,  A61K31/415 ,  A61K31/416 ,  A61K31/417 ,  A61K31/44 ,  A61K31/495 ,  A61K31/537 ,  A61K31/54 ,  C07D207/16 ,  C07D207/34 ,  C07D213/81 ,  C07D231/14 ,  C07D231/56 ,  C07D233/90

Abstract: Hetero-substituted acetanilide derivatives are disclosed as analgesic agents. The compounds of the invention are useful in methods for treating a disease or condition in a mammal characterized by pain and/or fever.

Abstract translation: 杂芳取代的乙酰苯胺衍生物被公开为止痛剂。 本发明的化合物可用于治疗以疼痛和/或发烧为特征的哺乳动物的疾病或病症的方法。

公开(公告)号：US20050169874A1

公开(公告)日：2005-08-04

申请号：US11035634

申请日：2005-01-14

Applicant: Albert Zofchak ,  John Carson

Inventor： Albert Zofchak ,  John Carson

IPC: A61K8/87 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/00 ,  B01F17/00 ,  A61K7/06 ,  A61K7/11

CPC classification number: A61Q19/00 ,  A61K8/87 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q17/04 ,  B01F17/005

Abstract: The invention provides polymeric emulsifiers that: are useful in the manufacture of personal care products such as skin creams, sunscreens, hair conditioners and shampoos; have similar aesthetic properties as conventional surfactants when used in personal care product applications; and that are relatively free of the drawbacks associated with known anionic or nonionic polymeric emulsifiers. In certain embodiments, the invention provides o/w or w/o emulsions comprising cationic polyurethane emulsifiers (surfactants) or combinations of cationic polyurethane emulsifiers and conventional low HLB emulsifiers. Emulsions of the invention are useful as components of personal care products such as hair and skin care products and are functional and stable over a wide pH range.

Abstract translation: 本发明提供了聚合物乳化剂，其可用于制造个人护理产品，例如护肤霜，防晒剂，护发素和洗发剂; 在用于个人护理产品的应用中具有与常规表面活性剂相似的美学特性; 并且相对没有与已知的阴离子或非离子聚合乳化剂相关的缺点。 在某些实施方案中，本发明提供了包含阳离子聚氨酯乳化剂（表面活性剂）或阳离子聚氨酯乳化剂和常规低HLB乳化剂的组合的o / w或w / o乳液。 本发明的乳液可用作个人护理产品如毛发和护肤产品的组分，并且在宽的pH范围内是功能和稳定的。

公开(公告)号：US20050004163A1

公开(公告)日：2005-01-06

申请号：US10767712

申请日：2004-01-29

Applicant: Steven Coats ,  John Carson ,  Lou Neilson ,  Philip Pitis ,  Mark Schulz

Inventor： Steven Coats ,  John Carson ,  Lou Neilson ,  Philip Pitis ,  Mark Schulz

IPC: A61K31/439 ,  C07D451/02 ,  A61K31/46

CPC classification number: C07D451/02 ,  A61K31/439

Abstract: This invention is directed to 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives useful as δ-opioid or μ-opioid receptor modulators. Depending on their agonist or antagonist effect, the compounds are useful analgesics, immunosuppressants, antiinflammatory agents, agents for the treatment of neurological and psychiatric conditions, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents and agents for the treatment of respiratory diseases.

Abstract translation: 本发明涉及可用作δ-阿片样物质或μ-阿片受体调节剂的3-（二芳基亚甲基）-8-氮杂双环[3.2.1]辛烷衍生物。 根据其激动剂或拮抗剂的作用，化合物是有用的止痛剂，免疫抑制剂，抗炎剂，用于治疗神经和精神病症的药剂，用于药物和酒精滥用的药物，用于治疗胃炎和腹泻的药剂，用于治疗的心血管药剂和药剂 的呼吸系统疾病。