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    FUSION PROTEINS AND METHODS FOR STIMULATING PLANT GROWTH, PROTECTING PLANTS FROM PATHOGENS, AND IMMOBILIZING BACILLUS SPORES ON PLANT ROOTS
    23.
    发明申请
    FUSION PROTEINS AND METHODS FOR STIMULATING PLANT GROWTH, PROTECTING PLANTS FROM PATHOGENS, AND IMMOBILIZING BACILLUS SPORES ON PLANT ROOTS 有权
    用于刺激植物生长的融合蛋白质和方法，保护植物从病原体和植物育苗中的苗木运动

    公开(公告)号：US20140274707A1

    公开(公告)日：2014-09-18

    申请号：US14213525

    申请日：2014-03-14

    Applicant: Spogen Biotech Inc.

    Inventor： Brian Thompson ,  Katie Thompson

    IPC: A01N63/02

    CPC classification number: C07K14/32 ,  A01N37/46 ,  A01N37/48 ,  A01N63/00 ,  A01N63/02 ,  C07K2319/035 ,  C12N9/0095 ,  C12N9/16 ,  C12N9/20 ,  C12N9/2402 ,  C12N9/2437 ,  C12N9/48 ,  C12Y118/06001 ,  C12Y301/01003 ,  C12Y301/03008 ,  C12Y302/01004 ,  C12Y304/00

    Abstract: The present invention is generally directed to fusion proteins containing a targeting sequence that targets the fusion protein to the exosporium of a Bacillus cereus family member. The invention also relates to recombinant Bacillus cereus family members expressing such fusion proteins, formulations containing the recombinant Bacillus cereus family members expressing the fusion proteins. Methods for stimulating plant growth and for protecting plants from pathogens by applying the recombinant Bacillus cereus family members or the formulations to plants or a plant growth medium are also described. The invention also relates to methods for immobilizing spores of a recombinant Bacillus cereus family member expressing a fusion protein on plant roots.

    Abstract translation: 本发明一般涉及含有将融合蛋白靶向蜡状芽孢杆菌家族成员的外植体的靶向序列的融合蛋白。 本发明还涉及表达这种融合蛋白的重组蜡状芽孢杆菌家族成员，包含表达融合蛋白的重组蜡状芽孢杆菌家族成员的制剂。 还描述了通过将重组蜡状芽孢杆菌家族成员或制剂施用于植物或植物生长培养基来刺激植物生长和保护植物免受病原体的方法。 本发明还涉及将表达融合蛋白的重组蜡状芽孢杆菌家族成员的孢子固定在植物根上的方法。

    COMPOSITIONS COMPRISING RECOMBINANT BACILLUS CELLS AND ANOTHER BIOLOGICAL CONTROL AGENT
    25.
    发明申请
    COMPOSITIONS COMPRISING RECOMBINANT BACILLUS CELLS AND ANOTHER BIOLOGICAL CONTROL AGENT 有权

    公开(公告)号：US20230069595A1

    公开(公告)日：2023-03-02

    申请号：US17852607

    申请日：2022-06-29

    Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

    Inventor： Damian CURTIS ,  Brian Thompson

    IPC: A01N63/50 ,  C07K14/325 ,  C12N15/63 ,  C12N15/82 ,  C12N15/866

    Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

    Compositions comprising recombinant Bacillus cells and an insecticide
    26.
    发明授权
    Compositions comprising recombinant Bacillus cells and an insecticide 有权

    公开(公告)号：US11044916B2

    公开(公告)日：2021-06-29

    申请号：US15511864

    申请日：2015-09-17

    Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

    Inventor： Damian Curtis ,  Brian Thompson

    IPC: A01N63/00

    Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

    Compositions comprising recombinant Bacillus cells and an insecticide
    27.
    发明授权
    Compositions comprising recombinant Bacillus cells and an insecticide 有权

    公开(公告)号：US10897909B2

    公开(公告)日：2021-01-26

    申请号：US15511864

    申请日：2015-09-17

    Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

    Inventor： Damian Curtis ,  Brian Thompson

    IPC: A01N63/00

    Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

    COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS
    28.
    发明申请
    COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS 审中-公开

    公开(公告)号：US20200255851A1

    公开(公告)日：2020-08-13

    申请号：US16749576

    申请日：2020-01-22

    Applicant: Spogen Biotech Inc.

    Inventor： Brian Thompson ,  Michelle Leslie

    IPC: C12N15/82 ,  C12N9/64 ,  C12N9/24 ,  C07K14/32 ,  C07K14/415

    Abstract: Isolated bioactive priming peptides and bioactive priming compostions comprising bioactive priming polypeptides and/or inducer compounds are provided that are useful when applied to plants in agricultural formulations. Methods of using the isolated bioactive priming peptides and/or compositions are also provided which are applied exogenously to the surface of a plant or a plant cell membrane or endogenously to the interior of a plant or to a plant cell. The isolated bioactive priming peptides and/or bioactive priming compositions when applied to a plant, a plant part, or a plant growth medium or a rhizosphere in an area surrounding the plant or the plant part increase growth, yield, health, longevity, productivity, and/or vigor of a plant or a plant part and/or protect the plant or the plant part from disease, and/or increase the innate immune response of the plant or the plant part and/or improve the quality and/or quantity of juice obtained from a plant or plant part.

    Bioactive polypeptides for improvements in plant protection, growth and productivity
    29.
    发明授权
    Bioactive polypeptides for improvements in plant protection, growth and productivity 有权

    公开(公告)号：US10717767B2

    公开(公告)日：2020-07-21

    申请号：US16041059

    申请日：2018-07-20

    Applicant: Spogen Biotech Inc.

    Inventor： Brian Thompson ,  Michelle Leslie

    IPC: C07K14/32 ,  C07K14/195 ,  C07K14/27 ,  C07K14/245 ,  C12P21/02 ,  A01N37/46 ,  A01N63/10 ,  C07K14/21

    Abstract: Bioactive priming polypeptides are provided that are useful when applied to plants in agricultural formulations. Methods of using the formulations containing the bioactive priming polypeptides are also provided which are applied exogenously to the surface of a plant or a plant cell membrane or endogenously to the interior of a plant or to a plant cell. The bioactive priming polypeptides when applied to a plant, a plant part, or a plant growth medium or a rhizosphere in an area surrounding the plant or the plant part increase growth, yield, health, longevity, productivity, and/or vigor of a plant or a plant part and/or decrease abiotic stress in the plant or the plant part and/or protect the plant or the plant part from disease, insects and/or nematodes, and/or increase the innate immune response of the plant or the plant part and/or change plant architecture.

    BIOACTIVE POLYPEPTIDES FOR IMPROVEMENTS IN PLANT PROTECTION, GROWTH AND PRODUCTIVITY
    30.
    发明申请
    BIOACTIVE POLYPEPTIDES FOR IMPROVEMENTS IN PLANT PROTECTION, GROWTH AND PRODUCTIVITY 审中-公开

    公开(公告)号：US20200170258A1

    公开(公告)日：2020-06-04

    申请号：US16631581

    申请日：2018-07-20

    Applicant: Spogen Biotech Inc.

    Inventor： Brian Thompson ,  Michelle Leslie

    IPC: A01N63/22 ,  C07K14/32 ,  C12N1/20 ,  A01N63/25 ,  A01N63/50 ,  C12P21/02

    Abstract: Bioactive priming polypeptides are provided that are useful when applied to plants in agricultural formulations. Methods of using the formulations containing the bioactive priming polypeptides are also provided which are applied exogenously to the surface of a plant or a plant cell membrane or endogenously to the interior of a plant or to a plant cell. The bioactive priming polypeptides when applied to a plant, a plant part, or a plant growth medium or a rhizosphere in an area surrounding the plant or the plant part increase growth, yield, health, longevity, productivity, and/or vigor of a plant or a plant part and/or decrease abiotic stress in the plant or the plant part and/or protect the plant or the plant part from disease, insects and/or nematodes, and/or increase the innate immune response of the plant or the plant part and/or change plant architecture.

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