公开(公告)号：US08481951B2

公开(公告)日：2013-07-09

申请号：US13002484

申请日：2009-07-03

Applicant: Yves Jongen ,  Frédéric Stichelbaut

Inventor： Yves Jongen ,  Frédéric Stichelbaut

IPC: G21K1/02

CPC classification number: G01T1/169 ,  A61B6/4258 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087 ,  G01T1/1642

Abstract: The invention is related to the field of charged Hadron Therapy, i.e. radiation therapy using strongly interacting particles. More particularly, the invention relates to a detector and method for measuring the beam range of a charged hadron beam in a target object as well as the particle dose distribution in the target object.

Abstract translation: 本发明涉及充电强子治疗领域，即使用强相互作用的颗粒的放射治疗。 更具体地，本发明涉及一种用于测量目标物体中的带电荷的强子光束的光束范围以及目标物体中的粒子剂量分布的检测器和方法。

公开(公告)号：US08148922B2

公开(公告)日：2012-04-03

申请号：US12539347

申请日：2009-08-11

Applicant: Marshall R. Cleland ,  Richard A. Galloway ,  Leonard DeSanto ,  Yves Jongen

Inventor： Marshall R. Cleland ,  Richard A. Galloway ,  Leonard DeSanto ,  Yves Jongen

IPC: H05H7/00

CPC classification number: H05H15/00 ,  H05H5/00 ,  H05H5/02

Abstract: A dc accelerator system able to accelerate high currents of proton beams at high energies is provided. The accelerator system includes a dc high-voltage, high-current power supply, an evacuated ion accelerating tube, a proton ion source, a dipole analyzing magnet and a vacuum pump located in the high-voltage terminal. The high-current, high-energy dc proton beam can be directed to a number of targets depending on the applications such as boron neutron capture therapy BNCT applications, NRA applications, and silicon cleaving.

Abstract translation: 提供了能够以高能量加速质子束高电流的直流加速器系统。 加速器系统包括位于高压端子中的直流高压，大电流电源，抽真空离子加速管，质子离子源，偶极子分析磁体和真空泵。 高电流，高能量直流质子束可以根据诸如硼中子俘获治疗BNCT应用，NRA应用和硅裂解的应用而被引导到多个靶。

公开(公告)号：US20110137159A1

公开(公告)日：2011-06-09

申请号：US12961172

申请日：2010-12-06

Applicant: Yves Jongen ,  Rudi Labarbe

Inventor： Yves Jongen ,  Rudi Labarbe

IPC: A61B5/05

CPC classification number: A61N5/1049 ,  A61B6/0421 ,  A61N5/1065 ,  A61N5/1069 ,  A61N2005/1087

Abstract: A device is provided for positioning a target volume, such as a phantom or a patient, in a radiation therapy apparatus. The apparatus directs a radiation beam towards the target. The apparatus can include a target support whereon the target is immobilized, a two dimensional radiation detector fixed with fixations means in a known geometric relationship to the target support, the radiation detector being capable of detecting the position of intersection of the radiation beam with the detector, and correcting means for correcting the relative position of the beam and the target support, based on the detected intersection position.

Abstract translation: 提供了用于在放射治疗装置中定位目标体积（例如体模或患者）的装置。 该装置将辐射束引向目标。 该装置可以包括目标固定在其上的目标支撑体，一个二维辐射探测器，固定有与目标支架已知几何关系的固定装置，该辐射探测器能够检测辐射束与探测器的相交位置 以及校正装置，用于基于检测到的交叉位置校正光束和目标支持体的相对位置。

公开(公告)号：US20110089329A1

公开(公告)日：2011-04-21

申请号：US12935254

申请日：2009-03-30

Applicant: Yves Jongen ,  Martin Arnold ,  Yves Claereboudt ,  Damien Prieels

Inventor： Yves Jongen ,  Martin Arnold ,  Yves Claereboudt ,  Damien Prieels

IPC: G01T1/29

CPC classification number: G01T1/2935

Abstract: The present invention relates to a detector for measuring characteristics of an energetic particle beam generated by a radiation source, the detector including means to vary the incoming particle beam energy; a plurality of sensors arranged in parallel; and processing means capable of processing signals coming from said sensors in correlation with said energy variation.

Abstract translation: 本发明涉及一种用于测量由辐射源产生的能量粒子束的特性的检测器，该检测器包括改变进入的粒子束能量的装置; 多个并联布置的传感器; 以及能够处理与所述能量变化相关的来自所述传感器的信号的处理装置。

公开(公告)号：US07860216B2

公开(公告)日：2010-12-28

申请号：US12096990

申请日：2006-12-12

Applicant: Yves Jongen ,  Rudi Labarbe

Inventor： Yves Jongen ,  Rudi Labarbe

IPC: G01K5/08

CPC classification number: A61N5/1049 ,  A61B6/0421 ,  A61N5/1065 ,  A61N5/1069 ,  A61N2005/1087

Abstract: Device for positioning a target volume (112) such, as a phantom or a patient in a radiation therapy apparatus, said apparatus directing a radiation beam (405) towards said target (112), characterized in that it comprises:—a target support (100) whereon the target is immobilized; a two dimensional radiation detector (103) fixed with fixations means (101, 102, 104, 106 107; 301, 302, 304, 305, 306; 208, 209) in a known geometric relationship to said target support (100), said radiation detector (103) being capable of detecting the position of intersection of said radiation beam (105) with said detector (103); correcting means for correcting the relative position of said beam (105) and said target support 100), based on said detected intersection position.

Abstract translation: 用于在放射治疗设备中定位目标体积（112）的装置，例如幻影或患者，所述装置将辐射束（405）引向所述目标（112），其特征在于，其包括：目标支撑 100）目标固定在哪里 以与所述目标支撑件（100）已知的几何关系固定的固定装置（101,102,104,106,107; 301,302,304,305,306,208,209）的二维辐射检测器（103），所述 辐射检测器（103）能够检测所述辐射束（105）与所述检测器（103）的交叉位置; 校正装置，用于基于所述检测到的交叉位置来校正所述光束（105）和所述目标支撑件100的相对位置。

公开(公告)号：US20060104401A1

公开(公告)日：2006-05-18

申请号：US10537975

申请日：2003-12-10

Applicant: Yves Jongen ,  Jozef Comor

Inventor： Yves Jongen ,  Jozef Comor

IPC: G21G1/10 ,  G21C23/00

CPC classification number: G21G1/10

Abstract: The present invention is related to a device and a method for producing a radioisotope of interest from a target fluid irradiated with a beam of accelerated charged particles, the device includes in a circulation circuit (17): an irradiation cell (1) having a metallic insert (2) able to form a cavity (8) designed to house the target fluid and closed by an irradiation window (7), the cavity (8) including at least one inlet (4) and at least one outlet (5); a pump (16) for circulating the target fluid inside the circulation circuit (17); an external heat exchanger (15); the pump (16) and the external heat exchanger (15) forming external cooling means of the target fluid; the device means for pressurizing (14) of the circulation circuit (17) and the external cooling means of the target fluid are arranged in such a way that the target fluid remains inside the cavity (8) essentially in the liquid state during the irradiation.

Abstract translation: 本发明涉及一种用于由照射有加速带电粒子束的目标流体生产感兴趣的放射性同位素的装置和方法，该装置包括在循环回路（17）中：具有金属 插入件（2），其能够形成设计成容纳目标流体并被辐照窗（7）封闭的空腔（8），空腔（8）包括至少一个入口（4）和至少一个出口（5）; 用于使目标流体循环在循环回路（17）内的泵（16）; 外部热交换器（15）; 所述泵（16）和所述外部热交换器（15）形成所述目标流体的外部冷却装置; 用于对循环回路（17）进行加压（14）的装置和目标流体的外部冷却装置以使得目标流体在照射期间基本上保持在液体状态的空腔（8）内的方式被布置。

公开(公告)号：US6057655A

公开(公告)日：2000-05-02

申请号：US51306

申请日：1998-04-03

Applicant: Yves Jongen

Inventor： Yves Jongen

IPC: H05H7/10 ,  H05H13/00

CPC classification number: H05H13/00 ,  H05H7/10

Abstract: A method for extracting a charged particle beam out of an isochronous cyclotron (1) comprising an electromagnet forming a magnetic circuit that includes at least a number of sectors (3, 3') known as "hills" where the air-gap is reduced, and separated by sector-shaped spaces (4) known as "valleys" where the air-gap is larger. According to the extraction method, the particle beam is extracted without using an extraction device as the magnetic field has a special arrangement produced by designing the electromagnet air-gap at the "hills" (3, 3') of the isochronous cyclotron in such a way that the aspect ratio between the electromagnet air-gap at the "hills" in the region of the maximum radius, and the radius gain per turn of the particles accelerated by the cyclotron at said radius is less than 20.

Abstract translation: PCT No.PCT / BE96 / 00101 Sec。 371日期：1998年4月3日 102（e）1998年4月3日PCT PCT 1996年9月25日PCT公布。 公开号WO97 / 14279 日期1997年04月17日一种用于从包括形成磁路的电磁体的同步回旋加速器（1）中提取带电粒子束的方法，所述电磁体包括至少多个称为“山丘”的扇区（3,3'），其中空气 - 间隙被减少，并且被气隙较大的被称为“谷”的扇形空间（4）分开。 根据提取方法，在不使用提取装置的情况下提取粒子束，因为磁场具有通过在等速回旋加速器的“山丘”（3,3'）处设计电磁气隙而产生的特殊布置 在最大半径区域中的“山丘”处的电磁铁气隙与在所述半径处由回旋加速器加速的颗粒的每转的半径增益之间的纵横比小于20的方式。

公开(公告)号：US4771208A

公开(公告)日：1988-09-13

申请号：US10280

申请日：1986-12-29

Applicant: Yves Jongen ,  Guido Ryckewaert

Inventor： Yves Jongen ,  Guido Ryckewaert

IPC: H05H13/00

CPC classification number: H05H13/00

Abstract: A non-superconductive cyclotron comprises a magnetic circuit comprising at least three sectors called "hills", wherein the air-gap is reduced to a size similar to that of the accelerated beam and wherein the magnetic flux is substantially concentrated. The hills are separated by spacings configured like sectors called "valleys" wherein the air-gap is a very large size so that the magnetic flux is essentially null. The magnetic circuit is further comprised of a single pair of coils which are substantially circular and surround the hills and valleys.

Abstract translation: PCT No.PCT / BE86 / 00014 Sec。 一九八六年十二月二十九日 102（e）日期1986年12月29日PCT提交1986年4月30日PCT公布。 出版物WO86 / 0692400 日期：1986年11月20日。非超导回旋加速器包括包括称为“小丘”的至少三个扇区的磁路，其中气隙被减小到与加速束相似的尺寸，并且其中磁通量基本上 集中。 丘陵由被称为“谷”的扇区分开，其中气隙是非常大的尺寸，使得磁通量基本上为零。 磁路进一步包括一对线圈，其基本上是圆形并围绕着山丘和山谷。

公开(公告)号：US09289624B2

公开(公告)日：2016-03-22

申请号：US13502946

申请日：2012-04-19

Applicant: Yves Jongen

Inventor： Yves Jongen

IPC: H01J3/26 ,  A61N5/10 ,  G21K1/093 ,  G21K5/04

CPC classification number: A61N5/10 ,  A61N5/1081 ,  A61N2005/1087 ,  G21K1/093 ,  G21K5/04

Abstract: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a gantry for delivering particle beams which comprises means to analyse the incoming beam. Means are integrated into the gantry to limit the momentum spread of the beam and/or the emittance of the beam.

Abstract translation: 本发明涉及用于放射治疗的颗粒治疗装置。 更具体地说，本发明涉及一种用于传送粒子束的台架，其包括分析入射光束的装置。 装置被集成到台架中以限制梁的动量扩展和/或束的发射。

公开(公告)号：US08766218B2

公开(公告)日：2014-07-01

申请号：US13498131

申请日：2012-03-23

Applicant: Yves Jongen

Inventor： Yves Jongen

IPC: H01J3/26

CPC classification number: H01J3/26 ,  A61N5/01 ,  A61N5/10 ,  A61N5/1077 ,  A61N5/1081 ,  A61N2005/1087 ,  G21K1/093

Abstract: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a compact isocentric gantry for delivering particle beams perpendicularly to a rotation axis of the gantry. The gantry comprises three dipole magnets. The angle of the last dipole magnet is smaller than 90° and a most preferred bending angle for this last dipole magnet is 60°.

Abstract translation: 本发明涉及用于放射治疗的颗粒治疗装置。 更具体地，本发明涉及一种用于沿垂直于台架的旋转轴线输送颗粒束的紧凑型等中心台架。 龙门架包括三个偶极子磁体。 最后的偶极子磁体的角度小于90°，​​最后的偶极子磁体的最佳弯曲角度为60°。