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公开(公告)号：US20170360309A1
公开(公告)日：2017-12-21
申请号：US15625710
申请日：2017-06-16
Applicant: Novadaq Technologies Inc.
Inventor： Frederick Allen MOORE , Lesley Myron OTSIG , Muhammad Nasir al-Din bin ZULKAFLY , Theodore Drew Fast HUSBY
CPC classification number: A61B5/0205 , A61B1/00 , A61B1/043 , A61B5/00 , A61B5/02007 , A61B5/14546 , A61B5/418 , A61K49/0017 , A61K49/0045
Abstract: Closed cavity adjustable sensor mount systems and methods are disclosed. The sensor mount systems include a sealed, closed cavity enclosing a sensor and forming a closed cavity sensor assembly. The closed cavity sensor assembly may be tilted and/or translated relative to a platform in order to adjust the orientation of the sensor to align it with an imaging optical axis. Following alignment, the closed cavity sensor assembly may be permanently or reversibly fixed in place. The closed cavity adjustable sensor mount systems may be part of medical imaging systems such as endoscopic imaging systems and/or open field imaging systems.
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公开(公告)号：US09814378B2
公开(公告)日：2017-11-14
申请号：US15247419
申请日：2016-08-25
Applicant: Novadaq Technologies Inc.
Inventor： Frederick Allen Moore
IPC: F21V13/02 , F21V9/00 , A61B1/12 , A61B1/06 , F21V29/70 , F21V5/04 , F21V9/08 , F21K9/60 , F21V29/89 , A61B5/00 , F21V15/01 , F21V23/02 , F21V8/00 , G02B23/24 , F21Y101/00 , F21Y115/30 , F21Y115/10 , F21Y113/13 , A61B90/30 , F21Y103/10
CPC classification number: A61B1/128 , A61B1/063 , A61B1/0638 , A61B1/0684 , A61B5/0071 , A61B2090/306 , A61B2090/309 , F21K9/60 , F21V5/04 , F21V9/08 , F21V15/01 , F21V23/02 , F21V29/70 , F21V29/89 , F21Y2101/00 , F21Y2103/10 , F21Y2113/13 , F21Y2115/10 , F21Y2115/30 , G02B6/0001 , G02B23/2469
Abstract: An apparatus for providing a light output to an optical guide for illumination of an imaged object including a plurality of solid state light-emitting sources each of which are independently powered and independently controlled, each light-emitting source emitting light at a wavelength which is different from the wavelength emitted by the other light-emitting sources. The apparatus also includes a heat sink configured to thermally couple the plurality of solid state light-emitting sources and provide conduction of heat generated by the plurality of solid state light-emitting sources. The apparatus further includes an optical elements to collect, collimate, and combine the emissions from the plurality of solid state light-emitting sources into a combined beam of light to be optically coupled to the light guide.
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公开(公告)号：US09642532B2
公开(公告)日：2017-05-09
申请号：US14873842
申请日：2015-10-02
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： John Fengler , Paul R. Westwick , Aurther E. Bailey , Paul Cottle
CPC classification number: A61B5/0086 , A61B1/00009 , A61B1/00043 , A61B1/00045 , A61B1/0005 , A61B1/00163 , A61B1/00186 , A61B1/04 , A61B1/042 , A61B1/043 , A61B1/045 , A61B1/06 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0062 , A61B5/0071 , A61B5/0075 , A61B5/418 , A61B5/7425 , G06T2207/10048 , H04N5/33 , H04N5/332
Abstract: An imaging system for acquisition of NIR and full-color images includes a light source providing visible light and NIR light to an area under observation, such as living tissue, a camera having one or more image sensors configured to separately detect blue reflectance light, green reflectance light, and combined red reflectance light/detected NIR light returned from the area under observation. A controller in signal communication with the light source and the camera is configured to control the light source to continuously illuminate area under observation with temporally continuous blue/green illumination light and with red illumination light and NIR excitation light. At least one of the red illumination light and NIR excitation light are switched on and off periodically in synchronism with the acquisition of red and NIR light images in the camera.
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公开(公告)号：US20160360956A1
公开(公告)日：2016-12-15
申请号：US15247419
申请日：2016-08-25
Applicant: Novadaq Technologies Inc.
Inventor： Frederick Allen MOORE
IPC: A61B1/12 , A61B5/00 , F21V8/00 , F21V5/04 , G02B23/24 , F21V29/70 , F21V23/02 , F21V29/89 , F21V15/01 , A61B1/06 , F21V9/08
CPC classification number: A61B1/128 , A61B1/063 , A61B1/0638 , A61B1/0684 , A61B5/0071 , A61B2090/306 , A61B2090/309 , F21K9/60 , F21V5/04 , F21V9/08 , F21V15/01 , F21V23/02 , F21V29/70 , F21V29/89 , F21Y2101/00 , F21Y2103/10 , F21Y2113/13 , F21Y2115/10 , F21Y2115/30 , G02B6/0001 , G02B23/2469
Abstract: An apparatus for providing a light output to an optical guide for illumination of an imaged object including a plurality of solid state light-emitting sources each of which are independently powered and independently controlled, each light-emitting source emitting light at a wavelength which is different from the wavelength emitted by the other light-emitting sources. The apparatus also includes a heat sink configured to thermally couple the plurality of solid state light-emitting sources and provide conduction of heat generated by the plurality of solid state light-emitting sources. The apparatus further includes an optical elements to collect, collimate, and combine the emissions from the plurality of solid state light-emitting sources into a combined beam of light to be optically coupled to the light guide.
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公开(公告)号：US20160270640A1
公开(公告)日：2016-09-22
申请号：US14975707
申请日：2015-12-18
Applicant: Novadaq Technologies Inc.
Inventor： John J.P. FENGLER , Francis REGAMEY
CPC classification number: A61B1/043 , A61B1/00006 , A61B1/00009 , A61B1/00045 , A61B1/00101 , A61B1/00186 , A61B1/05 , A61B1/0638 , A61B1/0646 , A61B1/0661 , G02B23/2423 , H04N5/2254 , H04N5/2256 , H04N2005/2255
Abstract: A fluorescence endoscopy video system includes a multi-mode light source that produces light for white light and fluorescence imaging modes. A filter is positioned at the distal end of an imaging endoscope so that the endoscope can produce fluorescence and white light images of a tissue sample.
Abstract translation: 荧光内窥镜视频系统包括产生用于白光和荧光成像模式的光的多模光源。 过滤器位于成像内窥镜的远端，使得内窥镜能够产生组织样本的荧光和白光图像。
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Patent Agency Ranking
公开(公告)号：US09421280B2
公开(公告)日：2016-08-23
申请号：US14177045
申请日：2014-02-10
Applicant: Novadaq Technologies Inc.
Inventor： Gurpreet Mangat , Lukasz Brzozowski , Richard L. Croft
CPC classification number: A61K49/0045 , A61K49/0019 , A61K49/0032 , A61K49/0034 , A61K49/0041 , A61K49/0043
Abstract: A method of determining the patency of a donor organ or at least one vessel to a donor organ in a donor subject includes administering a fluorescent dye to the donor subject, applying a sufficient amount of energy to the vessel such that the fluorescent dye fluoresces, obtaining a fluorescent image of the donor organ or the vessel attached to a donor organ, and observing the image to determine if a fluorescent signal is continuous through the vessel. A continuous fluorescent signal in the donor organ or vessel indicates the respective donor organ or vessel is patent.
Abstract translation: 确定给供体器官或至少一个血管对给体受体中供体器官的通畅性的方法包括向供体受试者施用荧光染料，向容器施加足够量的能量使得荧光染料发荧光，获得 供体器官或附着于供体器官的血管的荧光图像，并观察图像以确定荧光信号是否连续通过血管。 供体器官或血管中的连续荧光信号指示相应的供体器官或血管是专利的。
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公开(公告)号：US08965488B2
公开(公告)日：2015-02-24
申请号：US13850063
申请日：2013-03-25
Applicant: Novadaq Technologies Inc.
Inventor： Peter Dvorsky , David Mark Henri Goyette , T. Bruce Ferguson, Jr. , Cheng Chen
CPC classification number: A61B5/0275 , A61B5/0059 , A61B5/0261 , A61B5/489 , A61B5/7225 , A61B6/503 , A61B6/504 , A61B6/507 , A61B2576/02 , A61M5/007 , G06T7/0012 , G06T7/12 , G06T7/248 , G06T7/90 , G06T2207/10064 , G06T2207/30104
Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.
Abstract translation: 通过分析在心肌组织的荧光图像的集合中在静态感兴趣区域（ROI）中获得的荧光信号来确定血管灌注和心肌腮红。 腮红值是从图像元素的强度值的总强度确定的，该图像元素位于包含ROI内的所有图像元素的总测量图像强度的预定分数的图像强度值的最小连续范围内。 血管（动脉）峰强度由位于ROI内的图像元素确定，该图像元素具有最高测量图像强度值的最小相邻范围，并且包含ROI内所有图像元素的总测量图像强度的预定分数。 可以通过比较血管中峰值强度时间与手术前后相邻心肌组织区域的时间差来建立心脏功能。
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38.发明申请QUANTIFICATION OF ABSOLUTE BLOOD FLOW IN TISSUE USING FLUORESCENCE MEDIATED PHOTOPLETHYSMOGRAPHY 审中-公开使用荧光介质光电子显微镜对组织中绝对血液流量的定量公开(公告)号：US20140371583A1
公开(公告)日：2014-12-18
申请号：US14305950
申请日：2014-06-16
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： Robert W. FLOWER
IPC: A61B5/0275 , A61B5/00
CPC classification number: A61B5/0275 , A61B5/0071 , A61B5/0295 , A61B5/6826
Abstract: There is provided a method and a system for quantification of absolute blood flow in tissue using near-infrared fluorescence angiography in conjunction with photoplethysmography (fluorescence-mediated photoplethysmography). The method and system of the present invention provide absolute, real-time measurements of flow in terms of volume/time/area based upon measurement of fluorescence intensity.
Abstract translation: 提供了一种使用近红外荧光血管造影术结合光电体积描记术（荧光介导的光体积描记术）定量组织中绝对血流量的方法和系统。 本发明的方法和系统基于荧光强度的测量提供了在体积/时间/面积方面的流量的绝对的实时测量。
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39.发明申请VIRTUAL-REALITY SIMULATOR TO PROVIDE TRAINING FOR SENTINEL LYMPH NODE SURGERY USING IMAGE DATA AND DATABASE DATA 审中-公开虚拟现实模拟器使用图像数据和数据库数据为SENTINEL LYMPH NODE手术提供培训公开(公告)号：US20140212860A1
公开(公告)日：2014-07-31
申请号：US14170526
申请日：2014-01-31
Applicant: Novadaq Technologies Inc.
Inventor： Chuanyong Bai , Joel Kindem , Steve Yarnall , Richard Conwell
IPC: G09B23/28
CPC classification number: G09B23/28 , G09B23/285 , G09B23/30
Abstract: A virtual-reality method for surgical training simulates the task of detecting sentinel lymph nodes using a nuclear uptake probe. The simulator can be used with lymphoscintigraphic clinical imaging data to provide patient-specific training scenarios. In yet another embodiment, the apparatus can use a database representing mathematical phantoms to simulate different patient sizes, node distributions, node uptakes, and combinations thereof.
Abstract translation: 用于外科训练的虚拟现实方法模拟使用核吸收探针检测前哨淋巴结的任务。 模拟器可用于淋巴造影临床成像数据，以提供患者特定的训练场景。 在另一个实施例中，该装置可以使用表示数学模型的数据库来模拟不同的患者大小，节点分布，节点摄取及其组合。
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公开(公告)号：US20140187859A1
公开(公告)日：2014-07-03
申请号：US14140370
申请日：2013-12-24
Applicant: Novadaq Technologies Inc.
Inventor： Christopher LEEUW , John FENGLER , Danny Sherwinter
CPC classification number: A61M13/003 , A61B1/00135 , A61B1/00154 , A61B1/015 , A61B1/126 , A61B1/31 , A61B1/3132 , A61B17/3472 , A61B17/3474 , A61B2017/3445 , A61B2017/3452 , A61B2217/005 , A61B2217/007
Abstract: An introducer for use during endoscopic procedures provides insufflation, washing, and aspiration functions, and provides for the protection of the endoluminal surface during laparoscopic examination of an anastomosis or suture line following low anterior resection of the bowel. The introducer may be designed for the insertion of an endoscope capable of white light and/or near infra-red fluorescence imaging into the rectum for analysis of an anastomosis following low anterior resection of the bowel.
Abstract translation: 在内窥镜手术中使用的导引器提供吹气，洗涤和抽吸功能，并且在低肠前切除术后，在吻合口或缝合线的腹腔镜检查期间提供内窥镜表面的保护。 引导器可以被设计用于将能够进行白光和/或近红外荧光成像的内窥镜插入到直肠中，用于在肠前切除术后进行吻合分析。
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