公开(公告)号：US09610021B2

公开(公告)日：2017-04-04

申请号：US14598832

申请日：2015-01-16

Applicant: NOVADAQ TECHNOLOGIES INC.

Inventor： Peter Dvorsky ,  David Mark Henri Goyette ,  T. Bruce Ferguson, Jr. ,  Cheng Chen

IPC: A61B5/0275 ,  G06T7/40 ,  G06T7/00 ,  A61B5/00 ,  A61B6/00 ,  A61B5/026 ,  A61M5/00 ,  G06T7/20

CPC classification number: A61B5/0275 ,  A61B5/0059 ,  A61B5/0261 ,  A61B5/489 ,  A61B5/7225 ,  A61B6/503 ,  A61B6/504 ,  A61B6/507 ,  A61B2576/02 ,  A61M5/007 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/248 ,  G06T7/90 ,  G06T2207/10064 ,  G06T2207/30104

Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.

公开(公告)号：US08965488B2

公开(公告)日：2015-02-24

申请号：US13850063

申请日：2013-03-25

Applicant: Novadaq Technologies Inc.

Inventor： Peter Dvorsky ,  David Mark Henri Goyette ,  T. Bruce Ferguson, Jr. ,  Cheng Chen

IPC: A61B6/00 ,  A61B5/00 ,  A61B5/026 ,  A61M5/00

CPC classification number: A61B5/0275 ,  A61B5/0059 ,  A61B5/0261 ,  A61B5/489 ,  A61B5/7225 ,  A61B6/503 ,  A61B6/504 ,  A61B6/507 ,  A61B2576/02 ,  A61M5/007 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/248 ,  G06T7/90 ,  G06T2207/10064 ,  G06T2207/30104

Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.

Abstract translation: 通过分析在心肌组织的荧光图像的集合中在静态感兴趣区域（ROI）中获得的荧光信号来确定血管灌注和心肌腮红。 腮红值是从图像元素的强度值的总强度确定的，该图像元素位于包含ROI内的所有图像元素的总测量图像强度的预定分数的图像强度值的最小连续范围内。 血管（动脉）峰强度由位于ROI内的图像元素确定，该图像元素具有最高测量图像强度值的最小相邻范围，并且包含ROI内所有图像元素的总测量图像强度的预定分数。 可以通过比较血管中峰值强度时间与手术前后相邻心肌组织区域的时间差来建立心脏功能。