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    Compositions comprising recombinant bacillus cells and another biological control agent
    32.
    发明授权
    Compositions comprising recombinant bacillus cells and another biological control agent 有权

    公开(公告)号：US11154064B2

    公开(公告)日：2021-10-26

    申请号：US15511839

    申请日：2015-09-17

    Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

    Inventor： Damian Curtis ,  Brian Thompson

    IPC: C07K14/325 ,  A01N63/00 ,  A01N25/00 ,  A61K38/00 ,  A01N63/50 ,  C12N15/63 ,  C12N15/82 ,  C12N15/866 ,  C12N15/00

    Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

    FUSION PROTEINS, RECOMBINANT BACTERIA, AND EXOSPORIUM FRAGMENTS FOR PLANT HEALTH
    35.
    发明申请
    FUSION PROTEINS, RECOMBINANT BACTERIA, AND EXOSPORIUM FRAGMENTS FOR PLANT HEALTH 审中-公开

    公开(公告)号：US20200216828A1

    公开(公告)日：2020-07-09

    申请号：US16648810

    申请日：2018-09-20

    Applicant: Spogen Biotech Inc.

    Inventor： Brian M. Thompson ,  Jorg Augustin ,  Ashley Siegel

    IPC: C12N9/78 ,  C07K14/32 ,  A01N63/22 ,  A61K9/00 ,  C12N9/42 ,  C12N9/24 ,  A61K35/742 ,  A23K10/18 ,  A23K20/189

    Abstract: Fusion proteins containing a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member are provided. The fusion proteins further comprise an enzyme having ACC deaminase activity, a phospholipase, a lipase, a xylanase, a xylosidase, a lactonase, a chitosanase, a protease, a glucanase, a phytase, an acid phosphatase, a pectinase, a mannanase, and/or an expansin protein. Also provided are recombinant Bacillus cereus family members that express the fusion proteins, exosporium fragments derived from the recombinant Bacillus cereus family members, and formulations containing the recombinant Bacillus cereus family members or exosporium fragments. Plant seeds treated with the recombinant Bacillus cereus family members, exosporium fragments, or formulations are also provided. The invention further relates to methods for stimulating plant growth and/or promoting plant health using the recombinant Bacillus cereus family members, exosporium fragments, or formulations.

    BIOACTIVE POLYPEPTIDES FOR IMPROVEMENTS IN PLANT PROTECTION, GROWTH AND PRODUCTIVITY
    37.
    发明申请
    BIOACTIVE POLYPEPTIDES FOR IMPROVEMENTS IN PLANT PROTECTION, GROWTH AND PRODUCTIVITY 审中-公开

    公开(公告)号：US20190023750A1

    公开(公告)日：2019-01-24

    申请号：US16041059

    申请日：2018-07-20

    Applicant: Spogen Biotech Inc.

    Inventor： Brian Thompson ,  Michelle Leslie

    IPC: C07K14/32 ,  C07K14/195 ,  C07K14/245 ,  C07K14/21 ,  C07K14/27 ,  A01N63/02

    Abstract: Bioactive priming polypeptides are provided that are useful when applied to plants in agricultural formulations. Methods of using the formulations containing the bioactive priming polypeptides are also provided which are applied exogenously to the surface of a plant or a plant cell membrane or endogenously to the interior of a plant or to a plant cell. The bioactive priming polypeptides when applied to a plant, a plant part, or a plant growth medium or a rhizosphere in an area surrounding the plant or the plant part increase growth, yield, health, longevity, productivity, and/or vigor of a plant or a plant part and/or decrease abiotic stress in the plant or the plant part and/or protect the plant or the plant part from disease, insects and/or nematodes, and/or increase the innate immune response of the plant or the plant part and/or change plant architecture.

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