公开(公告)号：US20220071877A1

公开(公告)日：2022-03-10

申请号：US17309859

申请日：2019-12-17

Applicant: Colgate-Palmolive Company

Inventor： Camille Zenobia ,  Carlo DAEP ,  Dandan CHEN ,  Harsh Mahendra TRIVEDI ,  James MASTERS

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/21 ,  A61Q11/00

Abstract: Methods of shifting biofilm composition in an individuals oral cavity are disclosed. The methods comprise applying to the individuals oral cavity an oral care composition in an amount effective to shift biofilm composition to increase the amount from healthy bacteria in biofilm relative to pathogenic bacteria in biofilm. The oral care composition comprising: zinc oxide, zinc citrate, and arginine. The shift in biofilm composition provides a balance having a greater amount of healthy bacteria in biofilm compared to pathogenic bacteria.

公开(公告)号：US20210404006A1

公开(公告)日：2021-12-30

申请号：US17471914

申请日：2021-09-10

Applicant: Colgate-Palmolive Company ,  The Regents of the University of California

Inventor： David T.W. WONG ,  Karolina Elzbieta KACZOR-URBANOWICZ ,  Harsh Mahendra TRIVEDI ,  James MASTERS

IPC: C12Q1/6883

Abstract: Described herein are methods used for the detection of gingivitis and the monitoring of gingivitis in a subject.

公开(公告)号：US20200229909A1

公开(公告)日：2020-07-23

申请号：US16838373

申请日：2020-04-02

Applicant: Colgate-Palmolive Company

Inventor： Patrik JOHANSSON ,  John GATZEMEYER ,  Harsh Mahendra TRIVEDI ,  James MASTERS

IPC: A61C19/06 ,  C25B9/06 ,  C25B1/00 ,  A61N1/05 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/33 ,  A61K8/24 ,  A61K8/23

Abstract: In some embodiments, an oral care device includes a flexible base substrate, a power source disposed on the base substrate, and a flexible light source disposed on the base structure or on the power source. The flexible light source is in electrical communication with the power source. Also disclosed are methods of using the same, for example, for whitening the teeth or for treating other conditions in the oral cavity.

公开(公告)号：US20200206106A1

公开(公告)日：2020-07-02

申请号：US16717821

申请日：2019-12-17

Applicant: Colgate-Palmolive Company

Inventor： Dandan CHEN ,  Harsh Mahendra TRIVEDI ,  Ying YANG ,  James MASTERS

IPC: A61K8/24 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/25 ,  A61K8/04 ,  A61K8/02 ,  A61K8/365 ,  A61K8/27

Abstract: Methods of increasing sIgA and mucin 5B levels in an individual's oral cavity are disclosed. The methods comprise applying to the individual's oral cavity in an amount effective to increase sIgA and mucin 5B levels in the individual's oral cavity, an oral care composition comprising: zinc phosphate, stannous fluoride and optionally, an organic acid buffer system.

公开(公告)号：US20190275355A1

公开(公告)日：2019-09-12

申请号：US16425312

申请日：2019-05-29

Applicant: Colgate-Palmolive Company

Inventor： Ying YANG ,  Dandan CHEN ,  Robert D'AMBROGIO ,  Paul THOMSON ,  Harsh Mahendra TRIVEDI ,  Michael PRENCIPE ,  James MASTERS ,  Stanislav JARACZ

IPC: A61Q11/00 ,  A61K8/21 ,  A61Q17/00 ,  A61K8/365 ,  A61K8/35 ,  A61K8/34 ,  A61K8/22 ,  A61K36/9068 ,  A61K8/97 ,  A61K8/27 ,  A61K45/06

Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.

公开(公告)号：US20170367956A1

公开(公告)日：2017-12-28

申请号：US15533710

申请日：2015-12-17

Applicant: Colgate-Palmolive Company

Inventor： Dandan CHEN ,  Harsh Mahendra TRIVEDI ,  Peter R. HILLIARD, JR. ,  James MASTERS

IPC: A61K8/46 ,  A61Q11/00

CPC classification number: A61K8/466 ,  A61Q11/00

Abstract: Provided herein is an oral care composition comprising taurine or a salt thereof in an amount of from 0.001 weight % to 0.008 weight % by total weight of the composition, and an orally acceptable carrier. The composition is effective in accelerating HSP 27 production in damaged tissues of the oral cavity and enhances repair of the damaged tissue.