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    Methods and apparatus for treating congestive heart failure
    42.
    发明申请
    Methods and apparatus for treating congestive heart failure 有权
    治疗充血性心力衰竭的方法和装置

    公开(公告)号：US20060212078A1

    公开(公告)日：2006-09-21

    申请号：US11368553

    申请日：2006-03-06

    Applicant: Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Douglas Sutton ,  Howard Levin ,  Mark Gelfand

    Inventor： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Douglas Sutton ,  Howard Levin ,  Mark Gelfand

    IPC: A61N1/40 ,  A61N1/18

    CPC classification number: A61N1/05 ,  A61N1/0551 ,  A61N1/327 ,  A61N1/40

    Abstract: Methods and apparatus are provided for treating congestive heart failure, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

    Abstract translation: 提供了用于经由脉冲电场，经由刺激电场，经由局部药物递送，经由高频超声波，经由热技术等治疗充血性心力衰竭的方法和装置。这种神经调节可以实现不可逆的电穿孔或电融合， 凋亡的坏死和/或诱导，基因表达的改变，动作电位衰减或阻断，细胞因子上调的变化和靶神经纤维中的其他条件。 在一些实施方案中，神经调节被应用于有助于肾功能的神经纤维。 在一些实施方案中，这种神经调节以双向方式进行。 与单侧执行的肾神经调节相比，双侧肾神经调节可以在一些患者中提供增强的治疗效果，即与在支配单个肾脏的神经组织上进行的肾神经调节相比。

    Patient hydration system and method
    43.
    发明申请
    Patient hydration system and method 有权
    患者水合系统及方法

    公开(公告)号：US20060052764A1

    公开(公告)日：2006-03-09

    申请号：US10936945

    申请日：2004-09-09

    Applicant: Mark Gelfand ,  Howard Levin

    Inventor： Mark Gelfand ,  Howard Levin

    IPC: A61M31/00

    CPC classification number: A61M5/142 ,  A61B5/201 ,  A61B5/208 ,  A61B5/4839 ,  A61M5/007 ,  A61M5/16895 ,  A61M5/1723 ,  A61M5/365 ,  A61M2205/18 ,  A61M2205/3355 ,  A61M2205/3393 ,  G01G17/04

    Abstract: A patient hydration system and method wherein a urine collection system is connected to the patient. An infusion system is also connected to the patient. An infusion pump is connected to a source of hydration fluid. A control subsystem is responsive to the amount of urine output by the patient and configured to automatically adjust the infusion rate of the infusion pump based on the urine output by the patient.

    Abstract translation: 一种患者水合系统和方法，其中将尿液收集系统连接到患者。 输液系统也连接到患者身上。 输液泵连接到水合液源。 控制子系统响应于患者的尿量输出，并被配置为基于患者的尿液输出自动调节输液泵的输注速率。

    Method and apparatus for blood withdrawal and infusion using a pressure controller
    46.
    发明申请
    Method and apparatus for blood withdrawal and infusion using a pressure controller 有权
    使用压力控制器进行抽血和输液的方法和装置

    公开(公告)号：US20050230313A1

    公开(公告)日：2005-10-20

    申请号：US11154569

    申请日：2005-06-17

    Applicant: John O'Mahony ,  Mark Gelfand ,  Edward Rychlick

    Inventor： John O'Mahony ,  Mark Gelfand ,  Edward Rychlick

    IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  B01D61/00 ,  B01D61/22

    CPC classification number: A61M1/34 ,  A61M1/1692 ,  A61M1/341 ,  A61M1/3639 ,  A61M1/3656 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  B01D61/22

    Abstract: A method and apparatus for controlling blood withdrawal and infusion flow rate with the use of a pressure controller. The pressure controller uses pressure targets based upon occlusion limits that are calculated as a function of flow. The controller has the ability to switch from controlling withdrawal pressure to controlling infusion pressure based upon the detection of an occlusion. The controller distinguishes between partial and total occlusions of the withdrawal vein providing blood access. Depending on the nature of occlusion, the controller limits or temporarily reverses blood flow and, thus, prevents withdrawal vessel collapse or reverses blood flow to quickly infuse blood into the vessel without participation from operator.

    Abstract translation: 一种使用压力控制器控制取血和输注流速的方法和装置。 压力控制器使用基于作为流量的函数计算的阻塞极限的压力目标。 控制器能够根据遮挡的检测从控制提取压力转换到控制输液压力。 控制器区分提供血液通道的撤离静脉的部分和全部闭塞。 根据闭塞的性质，控制器限制或暂时逆转血液流动，从而防止撤离血管塌陷或逆转血液，以便在没有操作者参与的情况下将血液快速注入血管。

    Cardiopulmonary resuscitation system with centrifugal compression pump
    48.
    发明授权
    Cardiopulmonary resuscitation system with centrifugal compression pump 失效
    带离心压缩泵的心肺复苏系统

    公开(公告)号：US5997488A

    公开(公告)日：1999-12-07

    申请号：US53730

    申请日：1998-04-02

    Applicant: Mark Gelfand ,  Neil S. Rothman

    Inventor： Mark Gelfand ,  Neil S. Rothman

    IPC: A61H23/04 ,  A61H31/00

    CPC classification number: A61H9/0078 ,  A61H31/00 ,  A61H31/006 ,  A61H2031/025 ,  A61H2201/0103 ,  A61H2201/1238 ,  A61H2201/165 ,  A61H2201/5007 ,  A61H2201/5071 ,  A61H2230/04

    Abstract: A blower pressure source has been integrated into a vest cardiopulmonary resuscitation (CPR) system. The vest includes a bladder that cyclically inflates and deflates to provide automatic CPR to a patient in cardiac arrest or needing circulatory assistance to a patient with a beating but weakened heart. The blower continuously provides air at relatively low pressure to inflate a bladder in the vest. The maximum pressure of the blower corresponds to the desired peak vest pressure. A relatively simple valve, solenoid and timing controller is used to apply the blower air in cycles to inflate the bladder.

    Abstract translation: 鼓风机压力源已经整合到背心心肺复苏（CPR）系统中。 背心包括膀胱，其周期性地膨胀和放气以向心脏骤停患者提供自动CPR，或者需要向患有心跳但心脏衰弱的患者进行循环辅助。 鼓风机连续地提供相对较低压力的空气以使背心中的膀胱膨胀。 鼓风机的最大压力对应于所需的峰值背心压力。 使用相对简单的阀，螺线管和定时控制器来循环地施加鼓风机空气以使气囊膨胀。

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