公开(公告)号：US20240319080A1

公开(公告)日：2024-09-26

申请号：US18396404

申请日：2023-12-26

Applicant: Spogen Biotech Inc.

Inventor： Brian M. Thompson

IPC: G01N21/31 ,  G01J3/02 ,  G01N21/01 ,  G01N21/05 ,  G01N21/17 ,  G01N21/25 ,  G01N21/3577 ,  G01N21/64 ,  G01N21/77 ,  G01N21/78 ,  G01N21/80

CPC classification number: G01N21/31 ,  G01J3/0218 ,  G01N21/01 ,  G01N21/05 ,  G01N21/255 ,  G01N21/80 ,  G01N2021/0156 ,  G01N2021/1746 ,  G01N21/3577 ,  G01N2021/6439 ,  G01N2021/7786 ,  G01N21/78

Abstract: Systems, devices, and methods for detecting agrochemicals in environments associated with agricultural equipment are described. Certain agrochemicals that are formulated for being detected using the systems, devices, and methods disclosed herein are also described. The devices, systems, and methods disclosed herein are generally configured to use spectral characteristics to detect agrochemicals in an environment associated with agricultural equipment. The spectral characteristics can be analyzed in various ways to provide different types of information about the agrochemicals and/or the environment.

公开(公告)号：US20240285744A1

公开(公告)日：2024-08-29

申请号：US18644678

申请日：2024-04-24

Applicant: Spogen Biotech Inc. ,  Bayer CropScience LP

Inventor： Damian Curtis ,  Brian Thompson

IPC: A61K39/07 ,  A61K35/00 ,  A61K35/742

CPC classification number: A61K39/07 ,  A61K35/742 ,  C12Y301/01 ,  C12Y302/01004 ,  C12Y302/01132 ,  A61K2035/115 ,  Y02A50/30

Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

公开(公告)号：US20240228395A9

公开(公告)日：2024-07-11

申请号：US18476259

申请日：2023-09-27

Applicant: Spogen Biotech Inc.

Inventor： Brian M. Thompson ,  Jorg Augustin

IPC: C05F11/08 ,  A01N63/50 ,  C05B15/00 ,  C05C9/00 ,  C05F17/20 ,  C05G3/60 ,  C07K14/415 ,  C12N1/20 ,  C12N9/78 ,  C12N15/82

CPC classification number: C05F11/08 ,  A01N63/50 ,  C05B15/00 ,  C05C9/00 ,  C05F17/20 ,  C05G3/60 ,  C07K14/415 ,  C12N1/20 ,  C12N9/78 ,  C12N15/8237 ,  C12N15/8249 ,  C12N15/8279 ,  C12Y302/01 ,  C12Y305/99007 ,  C12Y402/0202 ,  Y02A40/22 ,  Y02P60/21

Abstract: Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided. Plant seeds coated with free enzymes or recombinant microorganisms that overexpress enzymes are also provided. Compositions comprising a fertilizer and an enzyme or a recombinant microorganism that overexpresses an enzyme are provided. Modified enzymes having ACC deaminase activity, recombinant microorganisms expressing the modified enzymes, plant seeds treated with the modified enzymes or recombinant microorganisms, and methods for stimulating plant growth and/or promoting plant health using the modified enzymes or recombinant microorganisms are also provided.

公开(公告)号：US12031164B2

公开(公告)日：2024-07-09

申请号：US16648810

申请日：2018-09-20

Applicant: Spogen Biotech Inc.

Inventor： Brian M. Thompson ,  Jorg Augustin ,  Ashley Siegel

IPC: C12N9/78 ,  A01N63/22 ,  A23K10/18 ,  A23K20/189 ,  A61K9/00 ,  A61K35/742 ,  A61K38/00 ,  C07K14/32 ,  C12N9/24 ,  C12N9/42

CPC classification number: C12N9/78 ,  A01N63/22 ,  A23K10/18 ,  A23K20/189 ,  A61K9/0056 ,  A61K35/742 ,  C07K14/32 ,  C12N9/2402 ,  C12N9/2434 ,  C12Y302/01151 ,  C12Y305/99007 ,  A61K38/00 ,  C07K2319/035

Abstract: Fusion proteins containing a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member are provided. The fusion proteins further comprise an enzyme having ACC deaminase activity, a phospholipase, a lipase, a xylanase, a xylosidase, a lactonase, a chitosanase, a protease, a glucanase, a phytase, an acid phosphatase, a pectinase, a mannanase, and/or an expansin protein. Also provided are recombinant Bacillus cereus family members that express the fusion proteins, exosporium fragments derived from the recombinant Bacillus cereus family members, and formulations containing the recombinant Bacillus cereus family members or exosporium fragments. Plant seeds treated with the recombinant Bacillus cereus family members, exosporium fragments, or formulations are also provided. The invention further relates to methods for stimulating plant growth and/or promoting plant health using the recombinant Bacillus cereus family members, exosporium fragments, or formulations.

公开(公告)号：US20240132419A1

公开(公告)日：2024-04-25

申请号：US18476270

申请日：2023-09-26

Applicant: Spogen Biotech Inc.

Inventor： Brian M. Thompson ,  Jorg Augustin

IPC: C05F11/08 ,  A01N63/50 ,  C05B15/00 ,  C05C9/00 ,  C05F17/20 ,  C05G3/60 ,  C07K14/415 ,  C12N1/20 ,  C12N9/78 ,  C12N15/82

CPC classification number: C05F11/08 ,  A01N63/50 ,  C05B15/00 ,  C05C9/00 ,  C05F17/20 ,  C05G3/60 ,  C07K14/415 ,  C12N1/20 ,  C12N9/78 ,  C12N15/8237 ,  C12N15/8249 ,  C12N15/8279 ,  C12Y302/01 ,  C12Y305/99007 ,  C12Y402/0202 ,  Y02A40/22 ,  Y02P60/21

Abstract: Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided. Plant seeds coated with free enzymes or recombinant microorganisms that overexpress enzymes are also provided. Compositions comprising a fertilizer and an enzyme or a recombinant microorganism that overexpresses an enzyme are provided. Modified enzymes having ACC deaminase activity, recombinant microorganisms expressing the modified enzymes, plant seeds treated with the modified enzymes or recombinant microorganisms, and methods for stimulating plant growth and/or promoting plant health using the modified enzymes or recombinant microorganisms are also provided.

公开(公告)号：US20230069595A1

公开(公告)日：2023-03-02

申请号：US17852607

申请日：2022-06-29

Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

Inventor： Damian CURTIS ,  Brian Thompson

IPC: A01N63/50 ,  C07K14/325 ,  C12N15/63 ,  C12N15/82 ,  C12N15/866

Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

公开(公告)号：US20220135492A1

公开(公告)日：2022-05-05

申请号：US17459031

申请日：2021-08-27

Applicant: Spogen Biotech Inc.

Inventor： Brian M. Thomas ,  Jorg Augustin

IPC: C05F11/08 ,  C05B15/00 ,  C12N9/78 ,  C05G3/60 ,  A01N63/50 ,  C05F17/20 ,  C05C9/00 ,  C07K14/415 ,  C12N1/20 ,  C12N15/82

Abstract: Methods for stimulating plant growth and/or promoting plant health using free enzymes or recombinant microorganisms that overexpress enzymes are provided. Plant seeds coated with free enzymes or recombinant microorganisms that overexpress enzymes are also provided. Compositions comprising a fertilizer and an enzyme or a recombinant microorganism that overexpresses an enzyme are provided. Modified enzymes having ACC deaminase activity, recombinant microorganisms expressing the modified enzymes, plant seeds treated with the modified enzymes or recombinant microorganisms, and methods for stimulating plant growth and/or promoting plant health using the modified enzymes or recombinant microorganisms are also provided.

公开(公告)号：US11044916B2

公开(公告)日：2021-06-29

申请号：US15511864

申请日：2015-09-17

Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

Inventor： Damian Curtis ,  Brian Thompson

IPC: A01N63/00

Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

公开(公告)号：US10897909B2

公开(公告)日：2021-01-26

申请号：US15511864

申请日：2015-09-17

Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

Inventor： Damian Curtis ,  Brian Thompson

IPC: A01N63/00

Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

公开(公告)号：US20200347102A1

公开(公告)日：2020-11-05

申请号：US16935020

申请日：2020-07-21

Applicant: Bayer CropScience LP ,  Spogen Biotech Inc.

Inventor： Damian CURTIS ,  Brian THOMPSON

IPC: C07K14/325 ,  A01N63/00 ,  C12N15/63 ,  C12N15/82 ,  C12N15/866

Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.