公开(公告)号：US20180154019A1

公开(公告)日：2018-06-07

申请号：US15570504

申请日：2016-04-29

Applicant: University of South Australia

Inventor： Nicolas Hans Voelcker ,  Steven James Peter McInnes ,  Christopher Travis Turner ,  Allison June Cowin

IPC: A61K47/69 ,  A61K47/52 ,  A61K47/42 ,  C07K16/24 ,  C07K16/18 ,  A61P17/02 ,  A61L15/32 ,  A61L15/42 ,  A61L15/44

Abstract: The present invention relates to a drug delivery system and uses thereof. Specifically, a system that can be used to deliver therapeutic proteins, including antibodies, to proteolytic environments is disclosed. In one form of the invention the drug delivery system is a composition which comprises a porous substrate and an antibody bound to the substrate. In one embodiment, the composition comprises nanoporous silicon and can be used to deliver antibodies for the treatment, or for improving the repair, of a wound.

公开(公告)号：US20170347340A1

公开(公告)日：2017-11-30

申请号：US15534424

申请日：2015-12-09

Applicant: University of South Australia

Inventor： David Victor Lawrie HALEY ,  William George COWLEY ,  John Lawrence BUETEFUER ,  Alexander James GRANT ,  Gottfried LECHNER ,  Andre POLLOK ,  Robert George MCKILLIAM ,  Ingmar Rudiger LAND ,  Marc Pierre Denis LAVENANT ,  Ying CHEN

IPC: H04W72/04 ,  H04L27/26

CPC classification number: H04W72/042 ,  H04L5/0007 ,  H04L5/0037 ,  H04L25/0204 ,  H04L25/03343 ,  H04L27/2657 ,  H04W72/044

Abstract: Methods and apparatus for communication between terminals and an access node in a multiuser multicarrier communications network are described. The access node may be a satellite access node. Terminals are configured to perform initial estimation and tracking of channel offsets and to estimate channel offsets for future packets to be transmitted by the terminal. In some embodiments the channel offsets comprise mobility related channel offsets due to the relative movement between the access node and the plurality of terminals. Transmissions from the terminals to the access node are pre-compensated for the channel offsets, so that the aggregate signal received by the access node occupies a bandwidth greater or equal to the maximum signal bandwidth of any individual terminal. Terminal transmissions may overlap in frequency and time on the ground, but arrive orthogonally at the access node.

公开(公告)号：US20170218477A1

公开(公告)日：2017-08-03

申请号：US15500751

申请日：2015-08-07

Applicant: UNIVERSITY OF SOUTH AUSTRALIA ,  SHANXI RUIENZE TECHNOLOGY CO. LTD ,  SHANXI UNIVERSITY

Inventor： Fangqin Cheng ,  Li Cui ,  Jingfang Zhou ,  John Ralston ,  Fangbin Xue

IPC: C22B3/26 ,  C01F7/62 ,  C21B15/00

CPC classification number: C22B3/004 ,  C01F7/62 ,  C21B15/00 ,  C22B3/0005 ,  Y02P10/234

Abstract: This disclosure relates to a process for selectively extracting Fe(III) ions from an aqueous feedstock containing Fe(III) ions and non-ferric ions. The process comprises contacting the feedstock with an organic phase comprising a phosphonium salt or ammonium salt ionic liquid under liquid-liquid extraction conditions for a time sufficient to allow transfer of at least some of the Fe(III) ions from the feedstock to the organic phase to provide an Fe(III) ion laden organic phase and an Fe(III) depleted feed-stock, and separating the Fe(III) ion laden organic phase from the Fe(III) depleted feedstock.

公开(公告)号：US20170190698A1

公开(公告)日：2017-07-06

申请号：US15321693

申请日：2015-06-26

Applicant: MONASH UNIVERSITY ,  UNIVERSITY OF SOUTH AUSTRALIA ,  SA PATHOLOGY

Inventor： Bernard Luke Flynn ,  Luigi Aurelio ,  Carmen Vittoria Scullino ,  Bing Hui Wang ,  Stuart Maxwell Pitson ,  Melissa Rose Pitman

IPC: C07D419/12 ,  C07D285/135 ,  C07D271/07 ,  C07D285/08 ,  C07D271/10 ,  C07D413/12 ,  C07D413/10 ,  C07D271/107 ,  C07D271/113 ,  C07D277/56

CPC classification number: C07D285/08 ,  C07D271/06 ,  C07D271/07 ,  C07D271/10 ,  C07D271/107 ,  C07D271/113 ,  C07D277/56 ,  C07D285/135 ,  C07D413/10 ,  C07D413/12 ,  C07D419/12

Abstract: The present disclosure relates generally, but not exclusively, to compounds and their use as enzyme interacting agents, in particular, agents which interact with one or more enzymes in the sphingolipid biosynthesis pathway. The disclosure further relates to the use of such compounds as research tools, use in therapy, to compositions and agents comprising said compounds, and to methods of treatment using said compounds.

公开(公告)号：US20170050039A1

公开(公告)日：2017-02-23

申请号：US15119848

申请日：2015-02-18

Applicant: UNIVERSITY OF SOUTH AUSTRALIA

Inventor： Robert David SHORT ,  Ian Michael GRIFFITHS ,  Endre Jazsef SZILI

IPC: A61N1/44 ,  A61L26/00 ,  A61L2/00

CPC classification number: A61N1/44 ,  A61L2/0011 ,  A61L2/14 ,  A61L2/23 ,  A61L26/0052 ,  A61L26/008

Abstract: Disclosed herein is a plasma treatment method comprising: providing a plasma source and a screen comprising a hydrogel and positioning the screen between the plasma source and a surface of a target to be treated with the plasma such that substantially all of the plasma from the plasma source passes through the screen prior to contacting the surface of the target and the screen reduces the concentration of one or more species from the plasma; and/or contacting a surface of a target to be treated with the gel composition comprising a gel forming material and a liquid phase comprising plasma activated liquid.

Abstract translation: 本文公开了一种等离子体处理方法，包括：提供等离子体源和包含水凝胶的筛网，并将筛网定位在等离子体源与要用等离子体处理的靶的表面之间，使得基本上所有来自等离子体源的等离子体 在接触靶的表面之前通过筛网，并且筛网从等离子体中减少一种或多种物质的浓度; 和/或使待处理的靶的表面与包含凝胶形成材料的凝胶组合物和包含等离子体活化液体的液相接触。

公开(公告)号：US09477312B2

公开(公告)日：2016-10-25

申请号：US13964828

申请日：2013-08-12

Applicant: UNIVERSITY OF SOUTH AUSTRALIA

Inventor： Thuong N. Hoang ,  Bruce Hunter Thomas ,  Ross Travers Smith

IPC: G06F3/01 ,  G06F3/0481

CPC classification number: G06F3/017 ,  G06F3/014 ,  G06F3/04815

Abstract: User input gloves and input methods are described that are well suited to provide input to computer modeling (eg CAD) and augmented reality (AR) systems, including wearable AR and spatial AR. Each glove comprises palm mounted ultrasonic transducers, accelerometers, finger based pinch inputs and a wireless communication module. The gloves can be used to measure distances over the natural range of distances that hands can be placed, as well as their orientation, with sufficient resolution to facilitate a range of gesture based input methods to be developed and utilized, including distance-based modeling by measurement. Further the gloves are light weight, allow fast input of modeling measurements, are easy to use, and reduce fatigue compared to existing glove based input systems. The user input gloves, and associated input techniques can be used to measure small and body sized objects using one or two hands, and large objects can be measured using single handed measurements. Further models for both small and large objects can be generated and manipulated through the use of a numeric input technique to obtain an amplification factor to magnify the effective distances measured.

Abstract translation: 描述了用户输入手套和输入方法，其非常适合于为计算机建模（例如CAD）和增强现实（AR）系统（包括可穿戴AR和空间AR）提供输入。 每个手套包括手掌式超声波换能器，加速度计，基于手指的夹点输入和无线通信模块。 手套可以用于测量手可以放置的距离的自然距离以及它们的方向上的距离，具有足够的分辨率，以便于开发和利用基于手势的输入方法的范围，包括基于距离的建模 测量。 此外，与现有的基于手套的输入系统相比，手套重量轻，允许快速输入建模测量，易于使用，并减少疲劳。 用户输入手套和相关的输入技术可用于使用一只或两只手测量小型和身体尺寸的物体，并且可以使用单手测量来测量大型物体。 可以通过使用数字输入技术来生成和操纵小型和大型物体的其他模型，以获得放大系数，以放大所测量的有效距离。

公开(公告)号：US20160277145A1

公开(公告)日：2016-09-22

申请号：US14913775

申请日：2014-08-22

Applicant: UNIVERSITY OF SOUTH AUSTRALIA

Inventor： Alexander James Grant ,  Andre Pollok ,  Gottfried Lechner ,  David Victor Lawrie Haley ,  Robert George McKilliam ,  Ingmar Rudiger Land ,  Marc Pierre Denis Lavenant

IPC: H04L1/00

CPC classification number: H04L1/0041 ,  H03M5/145 ,  H03M13/09 ,  H03M13/1102 ,  H03M13/23 ,  H03M13/2957 ,  H03M13/31 ,  H03M13/6325 ,  H03M13/6356 ,  H04L1/00 ,  H04L1/0045 ,  H04L1/0061 ,  H04L1/0071

Abstract: The invention relates to method and apparatus for improving the performance of communication systems using Run Length Limited (RLL) messages such as the existing Automatic Identification System (AIS). A binary data sequence is Forward Error Correction (FEC) coded and then the sequence is compensated, for example by bit-erasure, so that either bit-stuffing is not required, or a bit stuffer will not be activated to ensure that the coded sequence meets the RLL requirement. Various embodiments are described to handle different architectures or input points for the FEC encoder and bit erasure module. The bit erasure module may also add dummy bits to ensure a RLL compliant CRC or to selectively add bits to a reserve buffer to compensate for later bit stuffing in a header. Additional RLL training sequences may also be added to assist in, receiver acquisition.

Abstract translation: 本发明涉及使用诸如现有自动识别系统（AIS）的运行长度限制（RLL）消息来改善通信系统性能的方法和装置。 二进制数据序列是前向纠错（FEC）编码的，然后例如通过比特擦除来补偿序列，使得不需要任何一个比特填充，或者一个填充填充器将不被激活以确保编码序列 符合RLL要求。 描述了各种实施例来处理用于FEC编码器和位擦除模块的不同架构或输入点。 位擦除模块还可以添加虚拟位以确保符合RLL的CRC或者选择性地将位添加到保留缓冲器以补偿在标题中稍后的位填充。 还可以添加额外的RLL训练序列以辅助接收器采集。

公开(公告)号：US20160130661A1

公开(公告)日：2016-05-12

申请号：US14897612

申请日：2014-06-13

Applicant: UNIVERSITY OF SOUTH AUSTRALIA

Inventor： Doug Brooks ,  Emma Parkinson-Lawrence ,  Ian Johnson ,  Lisa Butler ,  Roberto WEIGERT

IPC: C12Q1/68 ,  C07K16/30 ,  A61N5/10 ,  G01N33/574

CPC classification number: C12Q1/6886 ,  A61N5/10 ,  C07K16/3069 ,  C07K2317/34 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  G01N33/57434 ,  G01N2333/4703 ,  G01N2333/82 ,  G01N2333/96455 ,  G01N2800/54

Abstract: The present disclosure relates to methods for detecting a prostate cancer. Certain embodiments of the present disclosure provide a method of detecting a prostate cancer in a subject, the method comprising detecting a marker selected from an endosomal associated marker and/or a lysosomal associated marker from the subject.

Abstract translation: 本公开涉及用于检测前列腺癌的方法。 本公开的某些实施方案提供了检测受试者中的前列腺癌的方法，所述方法包括从受试者中检测选自内体相关标志物和/或溶酶体相关标志物的标志物。

公开(公告)号：US20160059773A1

公开(公告)日：2016-03-03

申请号：US14936024

申请日：2015-11-09

Applicant: University of South Australia ,  SMR Patents S.A.R.L.

Inventor： Drew Raymond Evans ,  Kamil Zuber ,  Colin James Hall ,  Simon David Field

IPC: B60Q1/26 ,  B60Q1/34 ,  F21S8/10 ,  G02B27/14

CPC classification number: B60Q1/2665 ,  B60Q1/38 ,  C22C28/00 ,  C23C14/0015 ,  C23C14/024 ,  C23C14/20 ,  C23C14/205 ,  C23C14/228 ,  C23C14/35 ,  C23C28/00 ,  C23C30/00 ,  F21S43/26 ,  G02B27/142 ,  G02B27/144 ,  Y10T428/12 ,  Y10T428/12569 ,  Y10T428/12847 ,  Y10T428/265

Abstract: The present invention relates to a polymeric substrate being coated with a reflective coating, particularly a chromium-based reflective coating.

Abstract translation: 本发明涉及涂覆有反射涂层，特别是铬基反射涂层的聚合物基材。

公开(公告)号：US20150322405A1

公开(公告)日：2015-11-12

申请号：US14364200

申请日：2012-12-13

Applicant: FLINDERS UNIVERSITY OF SOUTH AUSTRALIA

Inventor： Yanchuang Han ,  Xin-Fu Zhou

IPC: C12N5/0797 ,  C12N5/0793 ,  C12N5/079

CPC classification number: C12N5/0623 ,  C12N5/0619 ,  C12N5/0622 ,  C12N2500/38 ,  C12N2501/065 ,  C12N2501/40 ,  C12N2501/72 ,  C12N2501/727 ,  C12N2501/999 ,  C12N2506/1307 ,  G01N33/5073

Abstract: The present invention provides a method of producing a multipotent stem cell, said method comprising culturing at least one fibroblast cell in the presence of an effective amount of at least one small molecule reprogramming factor(s) that induces the cell to de-differentiate into a multipotent stem cell, wherein the method excludes the use of reprogramming factor(s) that are not small molecules. The small molecule reprogramming factor(s) may include a G9a HMTase inhibitor(s) and/or a MEK inhibitor(s) optionally in combination with other small molecule reprogramming factor(s). The invention also includes methods of differentiating the multipotent stem cells, cells produced by the methods, assays using the cells and kits for use in the methods.

Abstract translation: 本发明提供了一种产生多能干细胞的方法，所述方法包括在存在有效量的至少一种小分子重编程因子的情况下培养至少一种成纤维细胞，所述小分子重编程因子诱导细胞脱分化为 多能干细胞，其中该方法不包括使用不是小分子的重编程因子。 小分子重编程因子可以包括任选与其它小分子重编程因子组合的G9a HMTase抑制剂和/或MEK抑制剂。 本发明还包括区分多能干细胞，通过该方法产生的细胞，使用细胞的测定法和用于该方法的试剂盒的方法。