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    MANAGED PACE RECHARGE IN A MULTIPOINT PACING SYSTEM
    41.
    发明申请
    MANAGED PACE RECHARGE IN A MULTIPOINT PACING SYSTEM 审中-公开
    多点控制系统中的管理补充

    公开(公告)号：US20160228708A1

    公开(公告)日：2016-08-11

    申请号：US15040483

    申请日：2016-02-10

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： David J. Ternes ,  William J. Linder

    IPC: A61N1/368 ,  A61N1/05 ,  H02J7/00

    Abstract: An apparatus comprises a stimulus circuit, a recharge circuit, a switch circuit, and a control circuit. The stimulus circuit provides electrical cardiac pacing stimulation to multiple combinations of a plurality of electrodes, and the electrical stimulation is selectively applied at the first electrode of the electrode combinations. The recharge circuit includes a recharge capacitor electrically coupled to the second electrode of the electrode combinations, and the switch circuit selectively enables electrode combinations for electrical coupling to the stimulus circuit and the recharge circuit. The control circuit includes a pacing activation sub-circuit that selectively initiates delivery of the electrical stimulation using multiple electrode combinations, and enables simultaneous delivery of pacing recharge energy from the recharge capacitor to the second electrode of multiple electrode combinations.

    Abstract translation: 一种装置包括刺激电路，再充电电路，开关电路和控制电路。 刺激电路为多个电极的多个组合提供电心脏起搏刺激，并且在电极组合的第一电极处选择性地施加电刺激。 再充电电路包括电耦合到电极组合的第二电极的再充电电容器，并且开关电路选择性地使电极组合用于与激励电路和再充电电路的电耦合。 控制电路包括起搏激活子电路，其使用多个电极组合选择性地启动电刺激的传递，并且能够将起搏再充电能量从再充电电容器同时传递到多个电极组合的第二电极。

    Discrimination of apnea type by medical device
    42.
    发明授权
    Discrimination of apnea type by medical device 有权
    医疗器械对呼吸暂停型的鉴别

    公开(公告)号：US09402563B2

    公开(公告)日：2016-08-02

    申请号：US14638142

    申请日：2015-03-04

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Pramodsingh Hirasingh Thakur ,  David J. Ternes ,  Stephen B. Ruble

    IPC: A61B5/02 ,  A61B5/08 ,  A61B5/00 ,  A61B7/02 ,  A61B5/053

    CPC classification number: A61B5/4818 ,  A61B5/02405 ,  A61B5/053 ,  A61B5/0809 ,  A61B5/0826 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B7/02 ,  A61B7/04 ,  A61B2560/0475

    Abstract: Disclosed herein, among other things, are methods and apparatus related to identification of apnea type. One aspect of the present subject matter provides a method for real-time apnea discrimination. The method includes sensing an impedance-based tidal volume signal to monitor a respiratory cycle of a patient, and detecting a reduction in tidal swing using the sensed impendence to detect an apnea event. When the apnea event is detected, a shape of the sensed signal is compared to a stored signal shape to determine whether the apnea event is primarily an obstructive sleep apnea (OSA) event or primarily a central sleep apnea (CSA) event, in various embodiments.

    Abstract translation: 本文公开了与呼吸暂停类型的鉴定相关的方法和装置。 本主题的一个方面提供了一种用于实时呼吸暂停辨别的方法。 该方法包括感测基于阻抗的潮气量信号以监测患者的呼吸周期，并且使用感测到的阻抗来检测潮汐摆动的减少以检测呼吸暂停事件。 当检测到呼吸暂停事件时，将感测信号的形状与存储的信号形状进行比较，以确定呼吸暂停事件是否主要是阻塞性睡眠呼吸暂停（OSA）事件或主要是中枢性睡眠呼吸暂停（CSA）事件，在各种实施例中 。

    Remote detection of physiological parameter using an implantable medical device
    44.
    发明授权
    Remote detection of physiological parameter using an implantable medical device 有权
    使用可植入医疗设备远程检测生理参数

    公开(公告)号：US09381358B2

    公开(公告)日：2016-07-05

    申请号：US14590480

    申请日：2015-01-06

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： David J. Ternes ,  Kenneth L. Baker

    IPC: A61N1/36 ,  A61B5/024 ,  G06F19/00 ,  A61N1/372

    CPC classification number: A61N1/36139 ,  A61B5/024 ,  A61N1/3605 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/36146 ,  A61N1/37211 ,  A61N1/37288 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481 ,  G16H20/10 ,  G16H40/63 ,  G16H40/67

    Abstract: A system embodiment for stimulating a neural target comprises a neural stimulator, a pace detector, and a controller. The neural stimulator is electrically connected to at least one electrode, and is configured to deliver a neural stimulation signal through the at least one electrode to stimulate the neural target. The pace detector is configured to use at least one electrode to sense cardiac activity and distinguish paced cardiac activity in the sensed cardiac activity from non-paced cardiac activity in the sensed cardiac activity. The controller is configured to control a programmed neural stimulation therapy using the neural stimulator and using detected paced cardiac activity as an input for the neural stimulation therapy.

    Abstract translation: 用于刺激神经目标的系统实施例包括神经刺激器，步速检测器和控制器。 神经刺激器电连接到至少一个电极，并且被配置为通过至少一个电极传递神经刺激信号以刺激神经靶标。 脚步检测器被配置为使用至少一个电极来感测心脏活动，并将感测到的心脏活动中的心跳活动与感觉到的心脏活动中的非节奏心脏活动区分开。 控制器被配置为使用神经刺激器来控制编程的神经刺激治疗，并使用检测到的起搏心脏活动作为神经刺激治疗的输入。

    SYSTEM AND METHOD FOR LOCATING NEURAL TISSUE
    47.
    发明申请
    SYSTEM AND METHOD FOR LOCATING NEURAL TISSUE 有权
    用于定位神经组织的系统和方法

    公开(公告)号：US20150173636A1

    公开(公告)日：2015-06-25

    申请号：US14570347

    申请日：2014-12-15

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Eric A. Mokelke ,  David J. Ternes ,  Allan Charles Shuros ,  Hong Cao

    IPC: A61B5/04 ,  A61B18/12 ,  A61N1/36

    CPC classification number: A61B5/04001 ,  A61B5/0538 ,  A61B5/4893 ,  A61B5/6848 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/124 ,  A61B2562/046 ,  A61N1/0551 ,  A61N1/36128 ,  A61N1/36139 ,  A61N1/36185

    Abstract: An example of a system comprises a patch of electrodes for placement on tissue containing neural tissue, and a tissue tester configured to measure an electrical characteristic of tissue. The tissue tester may include a test controller and switches. The test controller and the switches may be configured to connect different combinations of the electrodes to create subsets of two or more electrodes to measure the electrical characteristic of tissue using the subsets. The test controller may be configured to measure an electrical characteristic of tissue using the subsets within the set of electrodes placed on the tissue, and compare measurements of the electrical characteristic and identify a neural target for a therapy based on the comparison of the measurements of the electrical characteristic for tissue at the neural target relative to adjacent non-neural tissue.

    Abstract translation: 系统的示例包括用于放置在含有神经组织的组织上的电极片，以及被配置为测量组织的电特性的组织测试器。 组织测试器可以包括测试控制器和开关。 测试控制器和开关可以被配置为连接电极的不同组合以产生两个或更多个电极的子集，以使用子集来测量组织的电特性。 测试控制器可以被配置为使用放置在组织上的电极组内的子集来测量组织的电特性，并且比较电特性的测量并且基于对所述组合的测量的比较来识别用于治疗的神经靶标 相对于相邻非神经组织的神经靶标组织的电特性。

    Method for detecting vagus capture
    48.
    发明授权
    Method for detecting vagus capture 有权
    检测迷走神经捕获的方法

    公开(公告)号：US08818524B2

    公开(公告)日：2014-08-26

    申请号：US14012607

    申请日：2013-08-28

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Juan Gabriel Hincapie Ordonez ,  Stephen J. Hahn ,  David J. Ternes ,  Shantha Arcot-Krishnamurthy ,  Jason J. Hamann

    IPC: A61N1/00

    CPC classification number: A61B5/0492 ,  A61B5/0488 ,  A61B5/4035 ,  A61N1/0556 ,  A61N1/36053 ,  A61N1/36114

    Abstract: Some embodiments provide a system for delivering neurostimulation. Some system embodiments comprise a lead configured to be implanted in the body, a stimulation output circuit configured to deliver neurostimulation pulses to the vagus nerve through the lead, an EMG sensing circuit configured to use the lead to sense EMG signals from laryngeal muscle activity, and an evoked muscular response detection circuit configured to use the EMG signals sensed by the EMG sensing circuit to detect evoked laryngeal muscle activity evoked by the neurostimulation pulse.

    Abstract translation: 一些实施例提供用于递送神经刺激的系统。 一些系统实施例包括被配置为植入体内的引线，刺激输出电路，其经配置以通过引线将神经刺激脉冲输送到迷走神经; EMG感测电路，被配置为使用引线来感测来自喉部肌肉活动的EMG信号;以及 诱发肌肉反应检测电路，被配置为使用由EMG感测电路感测的EMG信号来检测由神经刺激脉冲诱发的诱发喉部肌肉活动。

    Managing cross therapy sensing in a multiple therapy implantable device
    50.
    发明授权
    Managing cross therapy sensing in a multiple therapy implantable device 有权
    在多种治疗植入式装置中管理交叉治疗感测

    公开(公告)号：US08688213B2

    公开(公告)日：2014-04-01

    申请号：US13660388

    申请日：2012-10-25

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： David J. Ternes ,  Douglas J. Brandner ,  Ramprasad Vijayagopal ,  Nicholas J. Stessman ,  William J. Linder ,  Keith R. Maile ,  Abhi V. Chavan

    IPC: A61N1/00

    CPC classification number: A61N1/3605 ,  A61B5/0428 ,  A61B5/4836 ,  A61B5/686 ,  A61B5/7217 ,  A61N1/36142 ,  A61N1/3704

    Abstract: An apparatus comprises a cardiac signal sensing circuit configured to sense an electrical cardiac signal from at least one of an atrium or ventricle of a heart of a subject, a therapy circuit configured to provide electrical pacing therapy and electrical autonomic neural modulation therapy to the subject, and a control circuit. The control circuit is configured to initiate delivery of the autonomic modulation neural therapy, and the control circuit includes a signal detection circuit configured to detect delivery of the autonomic neural modulation therapy in the sensed cardiac signal. The control circuit is configured to change, in response to detecting the delivery, a sensitivity of the cardiac signal sensing circuit during delivery of the autonomic neural modulation therapy.

    Abstract translation: 一种装置包括心脏信号感测电路，其被配置为感测来自受试者心脏的心房或心室中的至少一个的电心脏信号，被配置为向受试者提供电起搏治疗和电自主神经调节疗法的治疗电路， 和控制电路。 控制电路被配置为启动自主调制神经治疗的传递，并且控制电路包括被配置为检测所感测的心脏信号中的自主神经调节治疗的传递的信号检测电路。 控制电路被配置为响应于检测到传送而改变在传送自主神经调制疗法期间心脏信号感测电路的灵敏度。

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