公开(公告)号：US09629586B2

公开(公告)日：2017-04-25

申请号：US14518856

申请日：2014-10-20

Applicant: MC10 Inc.

Inventor： Roozbeh Ghaffari ,  Bassel de Graff ,  Gilman Callsen ,  William J. Arora ,  Benjamin Schlatka ,  Eugene Kuznetsov

IPC: A61N1/04 ,  A61B5/00 ,  A61B1/00 ,  A61B5/04 ,  A61B1/01 ,  A61B5/02 ,  A61B5/0205 ,  A61B8/14 ,  A61B18/02 ,  A61B18/14 ,  A61B18/20 ,  A61M5/172 ,  A61B5/01 ,  A61B5/145 ,  H01L27/146 ,  A61B18/00

CPC classification number: A61B5/4836 ,  A61B1/00082 ,  A61B1/01 ,  A61B5/00 ,  A61B5/0059 ,  A61B5/01 ,  A61B5/02028 ,  A61B5/02055 ,  A61B5/04001 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/6879 ,  A61B8/12 ,  A61B8/14 ,  A61B18/02 ,  A61B18/14 ,  A61B18/20 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2562/02 ,  A61B2562/0204 ,  A61B2562/0209 ,  A61B2562/0233 ,  A61B2562/0247 ,  A61B2562/046 ,  A61B2562/164 ,  A61M5/1723 ,  A61N1/04 ,  A61N5/062 ,  H01L27/14609

Abstract: System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a nerve bundle, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy.

公开(公告)号：US20170110417A1

公开(公告)日：2017-04-20

申请号：US15337389

申请日：2016-10-28

Applicant: MC10, Inc.

Inventor： William J. Arora ,  Roozbeh Ghaffari

IPC: H01L23/00 ,  H05K1/02 ,  H01L23/31 ,  H01L23/528 ,  H01L25/16 ,  H05K1/18 ,  H05K3/32

CPC classification number: H05K1/0283 ,  A61F2/958 ,  H01L23/3121 ,  H01L23/4985 ,  H01L23/52 ,  H01L23/528 ,  H01L23/564 ,  H01L25/16 ,  H01L2924/0002 ,  H05K1/00 ,  H05K1/189 ,  H05K3/326 ,  H05K2201/09263 ,  H05K2201/10106 ,  Y10T29/4913 ,  Y10T29/49155 ,  Y10T29/49204 ,  H01L2924/00

Abstract: In embodiments, the present invention may attach at least two isolated electronic components to an elastomeric substrate, and arrange an electrical interconnection between the components in a boustrophedonic pattern interconnecting the two isolated electronic components with the electrical interconnection. The elastomeric substrate may then be stretched such that the components separate relative to one another, where the electrical interconnection maintains substantially identical electrical performance characteristics during stretching, and where the stretching may extend the separation distance between the electrical components to many times that of the unstretched distance.

公开(公告)号：US20170105795A1

公开(公告)日：2017-04-20

申请号：US15382949

申请日：2016-12-19

Applicant: MC10, Inc.

Inventor： Stephen P. Lee ,  Clifford Liu ,  Roozbeh Ghaffari ,  John Work ,  Fernando Quivira ,  Lauren E. Klinker ,  Yung-Yu Hsu

IPC: A61B18/14

CPC classification number: A61B18/20 ,  A61B18/02 ,  A61B18/06 ,  A61B18/1492 ,  A61B18/1815 ,  A61B90/30 ,  A61B2018/00041 ,  A61B2018/00178 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00375 ,  A61B2018/00386 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/0212 ,  A61B2018/1861 ,  A61B2018/20361 ,  A61B2018/206 ,  A61B2018/2244 ,  A61B2090/065 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/36117 ,  A61N7/02

Abstract: Devices and methods are provided for performing an ablation procedure on tissue with flow monitoring using flow sensors. The devices include a catheter, and at least one flow sensor disposed on the catheter, and a component for applying the ablation procedure. An assessment module provides an indication of the efficacy of the ablation procedure based on the flow measurement from the flow sensor.

公开(公告)号：US20170019988A1

公开(公告)日：2017-01-19

申请号：US15208444

申请日：2016-07-12

Applicant: MC10, Inc.

Inventor： Bryan McGrane ,  Milan Raj ,  PingHung Wei ,  Briana Morey ,  Roozbeh Ghaffari ,  Monica Lin ,  Jeffrey Model ,  Xianyan Wang ,  Bryan Keen ,  Stephen Lee

IPC: H05K1/02 ,  H05K1/11 ,  H05K3/06 ,  H05K1/09 ,  H05K1/03 ,  A61B5/0496 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/0488 ,  H05K1/18 ,  H05K3/18

CPC classification number: A61B5/0496 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/053 ,  A61B5/6801 ,  A61B2562/164 ,  A61B2562/166 ,  H05K1/0209 ,  H05K1/0283 ,  H05K1/189 ,  H05K2201/0969 ,  H05K2201/10106 ,  H05K2201/10151 ,  H05K2201/10401 ,  H05K2201/2009 ,  H05K2203/1327

Abstract: A wearable device includes a flexible printed circuit board and one or more conductive stiffeners. The conductive stiffeners include a conductive surface that can be electrically or thermally connected to contact pads on the flexible printed circuit board. The wearable device can further include an adhesive layer or an encapsulation layer. The adhesive layer and the encapsulation layer can include conductive portions surrounded by non-conductive portions. The conductive portions can be aligned with the conductive stiffeners and together transmit electrical and/or thermal energy to the contact pads of the flexible printed circuit board.

Abstract translation: 可佩戴装置包括柔性印刷电路板和一个或多个导电加强件。 导电加强件包括导电表面，其可以电连接或热连接到柔性印刷电路板上的接触焊盘。 可穿戴装置还可包括粘合剂层或包封层。 粘合剂层和包封层可以包括被非导电部分包围的导电部分。 导电部分可以与导电加强件对准，并且一起将电和/或热能传递到柔性印刷电路板的接触垫。

公开(公告)号：US09516758B2

公开(公告)日：2016-12-06

申请号：US14488544

申请日：2014-09-17

Applicant: MC10, Inc.

Inventor： William J. Arora ,  Roozbeh Ghaffari

IPC: H05K1/18 ,  H05K3/32 ,  H01L23/498 ,  H01L23/52 ,  H01L23/528 ,  H01L23/00 ,  H05K1/02 ,  A61F2/958

CPC classification number: H05K1/0283 ,  A61F2/958 ,  H01L23/3121 ,  H01L23/4985 ,  H01L23/52 ,  H01L23/528 ,  H01L23/564 ,  H01L25/16 ,  H01L2924/0002 ,  H05K1/00 ,  H05K1/189 ,  H05K3/326 ,  H05K2201/09263 ,  H05K2201/10106 ,  Y10T29/4913 ,  Y10T29/49155 ,  Y10T29/49204 ,  H01L2924/00

Abstract: In embodiments, the present invention may attach at least two isolated electronic components to an elastomeric substrate, and arrange an electrical interconnection between the components in a boustrophedonic pattern interconnecting the two isolated electronic components with the electrical interconnection. The elastomeric substrate may then be stretched such that the components separate relative to one another, where the electrical interconnection maintains substantially identical electrical performance characteristics during stretching, and where the stretching may extend the separation distance between the electrical components to many times that of the un-stretched distance.

Abstract translation: 在实施例中，本发明可以将至少两个隔离的电子部件连接到弹性体基板上，并且以将两个隔离的电子部件与电互连互连的连接方式布置在组件之间的电互连。 然后弹性体基底可以被拉伸，使得部件相对于彼此分离，其中电互连在拉伸期间保持基本上相同的电性能特征，并且其中拉伸可将电气部件之间的间隔距离延伸到un 伸展距离。

公开(公告)号：US20160287177A1

公开(公告)日：2016-10-06

申请号：US15038401

申请日：2014-11-21

Applicant: MC10, INC.

Inventor： Gilbert Lee Huppert ,  Roozbeh Ghaffari ,  Melissa Ceruolo ,  Bryan Keen

IPC: A61B5/00 ,  A61B5/0476 ,  A61B5/0205 ,  A61B5/0488 ,  A61B5/0408 ,  A61M37/00

CPC classification number: A61B5/6833 ,  A61B5/0006 ,  A61B5/0022 ,  A61B5/01 ,  A61B5/02028 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/02444 ,  A61B5/0408 ,  A61B5/04085 ,  A61B5/04087 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/08 ,  A61B5/4815 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/4866 ,  A61B5/4875 ,  A61B5/7271 ,  A61B2560/0214 ,  A61B2560/0475 ,  A61B2562/0219 ,  A61B2562/08 ,  A61B2562/164 ,  A61M37/00

Abstract: Systems, methods and apparatuses for monitoring cardiac activity of an individual using a conformal cardiac sensor device are presented herein. A conformal cardiac sensor device for analyzing cardiac activity includes a flexible substrate for coupling to the user, and a heart sensor component embedded on/in the substrate. The heart sensor component contacts a portion of the users skin and measures electrical variable(s) indicative of cardiac activity. A biometric sensor component is embedded on/in the flexible substrate and measures physiological variable(s) indicative of cardiac activity of the user. A microprocessor, which is embedded on/in the flexible substrate, is communicatively coupled to the heart sensor component and biometric sensor component and operable to execute microprocessor executable instructions for controlling the measurements of electrical data and physiological data. A wireless communication component is embedded on/in the flexible substrate and is operable to transmit data indicative of the measurements obtained by the sensor components.

Abstract translation: 本文介绍了使用保形心脏传感器装置监测个体的心脏活动的系统，方法和装置。 用于分析心脏活动的适形心脏传感器装置包括用于与用户耦合的柔性基底和嵌入在基底上的心脏传感器部件。 心脏传感器组件接触用户皮肤的一部分并测量指示心脏活动的电变量。 将生物测定传感器组件嵌入到柔性基底上/内，并测量指示使用者的心脏活动的生理变量。 嵌入在柔性基板上的微处理器通信地耦合到心脏传感器部件和生物测定传感器部件，并可操作以执行用于控制电数据和生理数据的测量的微处理器可执行指令。 无线通信部件被嵌入在柔性基板上/内部，并且可操作地传送指示由传感器部件获得的测量值的数据。

公开(公告)号：US20160232807A1

公开(公告)日：2016-08-11

申请号：US15023556

申请日：2014-10-07

Applicant: MC10, INC.

Inventor： Roozbeh Ghaffari ,  Isaiah Kacyvenski ,  Conor Rafferty ,  Milan Raj ,  Melissa Ceruolo ,  Yung-Yu Hsu ,  Bryan Keen ,  Briana Morey ,  Brian Reilly ,  Ping-Hung Wei

IPC: G09B19/00 ,  H04W4/00

Abstract: Disclosed are systems, methods, and devices for sensing and analysis using conformal sensors. Aspects of this disclosure are directed to conformal sensor systems and devices for sensing and analysis of data indicative of body motion, e.g., for such applications as training and/or clinical purposes. According to the representative systems, methods, and devices disclosed in the specification, flexible electronics technology can be implemented as conformal sensors for sensing or measuring motion (including body motion and/or muscle activity), heart rate, electrical activity, and/or body temperature for such applications as medical diagnosis, medical treatment, physical activity, physical therapy and/or clinical purposes. The conformal sensors can be used for detecting and quantifying impact, and can be used for central nervous system disease monitoring.

Abstract translation: 公开了用于使用共形传感器进行感测和分析的系统，方法和装置。 本公开的方面涉及用于感测和分析指示身体运动的数据的适形传感器系统和装置，例如用于诸如训练和/或临床目的的应用。 根据说明书中公开的代表性系统，方法和设备，柔性电子技术可以被实现为用于感测或测量运动（包括身体运动和/或肌肉活动），心率，电活动和/或身体的保形传感器 医疗诊断，医疗，身体活动，物理治疗和/或临床目的等应用的温度。 保形传感器可用于检测和定量影响，可用于中枢神经系统疾病监测。

公开(公告)号：US20160213262A1

公开(公告)日：2016-07-28

申请号：US15047314

申请日：2016-02-18

Applicant: MC10, Inc.

Inventor： Roozbeh Ghaffari ,  Stephen Lee ,  John Work ,  John A. Wright, JR. ,  Lauren Klinker

IPC: A61B5/027 ,  A61B5/00 ,  A61B18/14

CPC classification number: A61B5/027 ,  A61B5/6851 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/22 ,  A61B34/25 ,  A61B34/35 ,  A61B90/30 ,  A61B90/70 ,  A61B2018/00005 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00386 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00494 ,  A61B2018/00511 ,  A61B2018/00517 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00648 ,  A61B2018/00666 ,  A61B2018/00672 ,  A61B2018/00678 ,  A61B2018/00708 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/00875 ,  A61B2018/0212 ,  A61B2018/1861 ,  A61B2034/252 ,  A61B2034/254 ,  A61B2090/065 ,  A61N1/0514 ,  A61N1/36007 ,  A61N1/36135 ,  A61N7/02

Abstract: Devices and methods are provided for performing procedure on tissue with flow monitoring using flow sensors. The devices include an elongated member, and at least one flow sensor disposed on the elongated member. The flow sensor includes at least one temperature sensor and at least one heating element having a cavity. At least a portion of the at least one temperature sensor is housed in the cavity. A temperature measurement of the temperature sensor provides an indication of the flow rate of a fluid proximate to the flow sensor.

公开(公告)号：US09295842B2

公开(公告)日：2016-03-29

申请号：US14147347

申请日：2014-01-03

Applicant: MC10, INC.

Inventor： Roozbeh Ghaffari ,  Stephen Lee ,  John Work ,  John A. Wright, Jr. ,  Lauren Klinker

IPC: A61B18/18 ,  A61N1/36 ,  A61B18/14 ,  A61B19/00 ,  A61N1/05 ,  A61B18/00 ,  A61N7/02 ,  A61B18/02 ,  A61B18/22

CPC classification number: A61B5/027 ,  A61B5/6851 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/22 ,  A61B34/25 ,  A61B34/35 ,  A61B90/30 ,  A61B90/70 ,  A61B2018/00005 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00386 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00494 ,  A61B2018/00511 ,  A61B2018/00517 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00648 ,  A61B2018/00666 ,  A61B2018/00672 ,  A61B2018/00678 ,  A61B2018/00708 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/00875 ,  A61B2018/0212 ,  A61B2018/1861 ,  A61B2034/252 ,  A61B2034/254 ,  A61B2090/065 ,  A61N1/0514 ,  A61N1/36007 ,  A61N1/36135 ,  A61N7/02

Abstract: Devices and methods are provided for performing procedure on tissue with flow monitoring using flow sensors. The devices include an elongated member, and at least one flow sensor disposed on the elongated member. The flow sensor includes at least one temperature sensor and at least one heating element having a cavity. At least a portion of the at least one temperature sensor is housed in the cavity. A temperature measurement of the temperature sensor provides an indication of the flow rate of a fluid proximate to the flow sensor.

Abstract translation: 提供了设备和方法，用于使用流量传感器进行具有流量监测的组织执行过程。 这些装置包括细长构件和设置在细长构件上的至少一个流量传感器。 流量传感器包括至少一个温度传感器和至少一个具有空腔的加热元件。 至少一个温度传感器的至少一部分容纳在空腔中。 温度传感器的温度测量提供了靠近流量传感器的流体的流量的指示。

公开(公告)号：US20160027834A1

公开(公告)日：2016-01-28

申请号：US14812197

申请日：2015-07-29

Applicant: MC10, Inc.

Inventor： Bassel de Graff ,  Gilman Callsen ,  William J. Arora ,  Roozbeh Ghaffari

IPC: H01L27/146

CPC classification number: H01L27/14636 ,  A61B1/04 ,  A61B5/01 ,  A61B5/145 ,  A61B2562/02 ,  A61B2562/0204 ,  A61B2562/0209 ,  A61B2562/0233 ,  A61B2562/0247 ,  A61B2562/046 ,  A61B2562/164 ,  H01L27/14609 ,  H01L27/14621 ,  H01L27/14683 ,  H01L27/14687 ,  H01L2224/18 ,  H01L2224/24 ,  H01L2224/24137 ,  H01L2224/82 ,  H01L2924/3512

Abstract: System, devices and methods are presented that provide an imaging array fabrication process method, comprising fabricating an array of semiconductor imaging elements, interconnecting the elements with stretchable interconnections, and transfer printing the array with a pre-strained elastomeric stamp to a secondary non-planar surface.