公开(公告)号：US11129696B2

公开(公告)日：2021-09-28

申请号：US16292126

申请日：2019-03-04

Applicant: University of Southern California

Inventor： Behrokh Khoshnevis ,  Hongsheng Tong ,  Yong Chen ,  Philong John Pham ,  Robert Lee

IPC: A61C7/30 ,  A61C7/12 ,  A61C7/28 ,  A61C7/20

Abstract: An orthodontic appliance may include an archwire and multiple orthodontic brackets. The archwire may fit within a human mouth and contain multiple male connectors. Each orthodontic bracket may have a configuration that facilitates attaching the orthodontic bracket to a single tooth. Each orthodontic bracket may allow one of the male connectors to be locked into the orthodontic bracket with a snapping action. The male connector may be unable to slide with respect to the orthodontic bracket after being locked in the orthodontic bracket. A manual unlocking action may allow the male connector to disengage from the orthodontic bracket.

公开(公告)号：US20200316258A1

公开(公告)日：2020-10-08

申请号：US16899363

申请日：2020-06-11

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Jay R. Lieberman ,  William Pannell ,  Yong Chen ,  Xuan Song ,  Sofia Bougioukli

IPC: A61L27/38 ,  A61L27/22 ,  A61L27/10 ,  A61L27/12 ,  A61L27/54 ,  B33Y80/00 ,  B33Y40/20 ,  B28B1/00 ,  B33Y70/00 ,  B29C64/379

Abstract: Disclosed herein are methods of regional gene-therapy with growth-factor transduced cells, in bone graft scenarios. In embodiments, the methods comprise use of 3D printed scaffolds.

公开(公告)号：US20200022816A1

公开(公告)日：2020-01-23

申请号：US16337893

申请日：2017-09-29

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Jay R. Lieberman ,  William Pannell ,  Yong Chen ,  Xuan Song ,  Sofia Bougioukli

IPC: A61F2/30 ,  A61L27/10 ,  A61F2/28 ,  A61L27/38 ,  A61L27/54 ,  A61K38/18

Abstract: A method for repairing a bone defect of a patient includes providing a ceramic scaffold configured for filling the bone defect, loading the scaffold with growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation, placing the ceramic scaffold with the growth factor transduced cells in or across the bone defect, and stabilizing the ceramic scaffold with the growth factor transduced cells in the patient until the bone defect is healed. An assembly for repairing a bone defect includes a ceramic scaffold configured for spanning the bone defect and a culture of live growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation loaded onto the ceramic scaffold.

公开(公告)号：US20180200947A1

公开(公告)日：2018-07-19

申请号：US15870628

申请日：2018-01-12

Applicant: University of Southern California

Inventor： Yong Chen ,  Jie Jin

IPC: B29C64/124 ,  B29C64/40 ,  B29C64/295 ,  B29C64/357 ,  B29C64/268 ,  B29C64/245 ,  B29C64/205

CPC classification number: B29C64/124 ,  B29C35/16 ,  B29C64/205 ,  B29C64/245 ,  B29C64/268 ,  B29C64/295 ,  B29C64/357 ,  B29C64/40 ,  B29C2035/1616 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/00

Abstract: Methods and apparatuses for additive manufacturing using stereolithography (“SLA”) materials. The apparatus includes a platform for holding an assembly of SLA resin layers. The apparatus also includes a platform for holding an assembly of SLA resin layers. The apparatus also includes a first movable stage for depositing and curing a portion of the liquid SLA resin on the platform, forming a pattern of cured SLA resin. The apparatus also includes a second movable stage for depositing a low-viscosity non-SLA material in voids in the pattern of cured SLA resin. The apparatus also includes a cooler for cooling the low-viscosity non-SLA material below its freezing point until solidified.

公开(公告)号：US20160303805A1

公开(公告)日：2016-10-20

申请号：US15099404

申请日：2016-04-14

Applicant: University of Southern California

Inventor： Yong Chen ,  Huachao Mao

IPC: B29C67/00 ,  G02B27/09 ,  G02B26/10 ,  G06K15/12 ,  H04N1/024

Abstract: The present disclosure describes systems and techniques relating to computer numerical control (CNC) additive manufacturing. According to an aspect, a tooltip for an additive manufacturing machine includes: an input end configured to receive light from an optical system; and an output end configured to deliver the light to a workpiece on a build platform in the additive manufacturing machine; wherein the output end of the tooltip is configured to be immersed in a liquid resin in a tank of the additive manufacturing machine, and the output end defines a linear opening through which the light is delivered to the workpiece on the build platform.

Abstract translation: 本公开描述了与计算机数控（CNC）添加剂制造相关的系统和技术。 根据一个方面，一种用于添加剂制造机的工具提示器包括：被配置为从光学系统接收光的输入端; 以及输出端，被配置为将光传送到所述添加剂制造机器中的构建平台上的工件; 其中工具提示的输出端被配置为浸入添加剂制造机器的罐中的液体树脂中，并且输出端限定了光线在构建平台上被输送到工件的线性开口。

公开(公告)号：US09427291B2

公开(公告)日：2016-08-30

申请号：US14067690

申请日：2013-10-30

Applicant: University of Southern California

Inventor： Behrokh Khoshnevis ,  Hongsheng Tong ,  Yong Chen ,  Philong John Pham ,  Robert Lee

IPC: A61C7/30 ,  A61C7/12 ,  A61C7/28 ,  A61C7/20

CPC classification number: A61C7/30 ,  A61C7/125 ,  A61C7/20 ,  A61C7/28

Abstract: An orthodontic appliance may include an archwire and multiple orthodontic brackets. The archwire may fit within a human mouth and contain multiple male connectors. Each orthodontic bracket may have a configuration that facilitates attaching the orthodontic bracket to a single tooth. Each orthodontic bracket may allow one of the male connectors to be locked into the orthodontic bracket with a snapping action. The male connector may be unable to slide with respect to the orthodontic bracket after being locked in the orthodontic bracket. A manual unlocking action may allow the male connector to disengage from the orthodontic bracket.

Abstract translation: 正畸器具可以包括弓丝和多个正畸托。 弓丝可以装配在人的嘴中并且包含多个公连接器。 每个正畸托架可以具有便于将正牙托架附接到单个牙齿的构造。 每个正畸托架可以允许一个公连接器以卡扣动作锁定到正畸托架中。 在插入正畸托架后，阳连接器可能无法相对于正畸托架滑动。 手动解锁动作可以允许公连接器脱离正畸托架。