Methods and systems for pure dye instrument normalization

    公开(公告)号:US09809849B2

    公开(公告)日:2017-11-07

    申请号:US15016713

    申请日:2016-02-05

    Inventor: Jeffrey Marks

    Abstract: The present teachings relate to a method and system for normalizing spectra across multiple instruments. In an embodiment of the present invention, the method comprises at least one reference instrument and a test instrument. Each instrument comprises at least one excitation filter and at least one emission filter arranged in pairs. Each instrument further comprises a pure dye plate comprising a plurality of wells. Each well contains a plurality of dyes where each dye comprises a fluorescent component. Fluorescent spectra are obtained from each instrument for each dye across multiple filter combinations to contribute to a pure dye matrix Mref for the reference instrument and pure dye matrix M for the test instrument. The pure dye spectra can then be multiplied by correction factors for each filter pair to result in corrected pure dye spectra, then normalized and the multicomponenting data can be extracted.

    Dent mirror
    43.
    发明授权

    公开(公告)号:US09791269B2

    公开(公告)日:2017-10-17

    申请号:US14472939

    申请日:2014-08-29

    CPC classification number: G01B11/306 G01N21/8803 G01N2201/0616 G01N2201/068

    Abstract: The present invention comprises a surface to maximize the viewing of an impression in a vehicle body. This may comprise a fabric which has at least one dark colored stripe parallel to at least one light colored stripe; a compressible frame across which the said fabric is affixed, where when the frame is uncompressed the fabric is stretched taut across the frame and where the frame is compressed the fabric is slack across the frame; and a handle on the frame where a user can hold the frame and not interfere with the fabric affixed to said frame. When a user is holding the handle of the frame at an angle between 0° and 180°, the user can reflect radiant energy through said fabric onto the vehicle body and create a whorl reflection pattern on the impression to maximize viewing of said impression by the user.

    Compact sensor for measuring turbidity or fluorescence in a fluid sample

    公开(公告)号:US09778180B2

    公开(公告)日:2017-10-03

    申请号:US14937240

    申请日:2015-11-10

    Applicant: In-Situ, Inc.

    CPC classification number: G01N21/532 G01N27/07 G01N2201/068

    Abstract: Provided are turbidometers and fluorometers having a unique form-factor to accommodate a number of optical components in a confined geometry. This provides the ability to compensate for change in light intensity from an optical source even in a closed-loop manner. The ability to package reference and signal detectors, along with a relatively large diameter LED light source in a confined geometry is particularly suited for applications requiring small-diameter sensors, such as multi-parameter sonde devices having a total diameter that is in the sub-two inch range.

    MID-INFRARED CEMENT SENSOR
    45.
    发明申请

    公开(公告)号:US20170242150A1

    公开(公告)日:2017-08-24

    申请号:US15511343

    申请日:2015-09-11

    Abstract: A sensor is provided for monitoring cement. An internal reflection is contacted with the cement and a mid-infrared light source directs a beam of mid-infrared radiation into said window for attenuated internal reflection at an interface between the window and the cement. The reflected infrared radiation is passed through a first narrow bandpass filter that preferentially transmits mid-infrared radiation over a band of wavelengths corresponding to an absorbance peak of a species associated with the cement to filter internally reflected mid-infrared radiation received from the window. An infrared detector detects filtered mid-infrared radiation transmitted through the first filter and a processor measures the intensity of the detected mid-infrared radiation transmitted through the first filter, and determines therefrom an amount of the species associated with the cement.

    Apparatus and method of investigating surface properties

    公开(公告)号:US09726597B2

    公开(公告)日:2017-08-08

    申请号:US14645831

    申请日:2015-03-12

    Abstract: The invention relates to an apparatus for the investigation of surface properties with a housing, a light source which directs light through an opening in the housing onto a surface to be investigated, with a first detector device which is arranged inside at a first pre-set angle with respect to the light beam radiated onto the surface by the light source, with a second detector device which is arranged at a second pre-set angle with respect to the light beam radiated onto the surface by the light source and with a third detector device which is arranged inside the housing at a third pre-set angle with respect to the light beam radiated onto the surface by the light source. According to the invention the apparatus has at least two filter elements with optical properties which are different from each other which are arranged on a common carrier movable with respect to the light source, in such a way that each of these filter elements is optionally capable of being brought into a beam path between the light source and the surface.

    Identification and Analysis of Materials and Molecular Structures

    公开(公告)号:US20170191939A1

    公开(公告)日:2017-07-06

    申请号:US15464114

    申请日:2017-03-20

    Applicant: Ondax, Inc.

    CPC classification number: G01N21/65 G01N21/3581 G01N2201/06113 G01N2201/068

    Abstract: Provided are methods and systems for identification and analysis of materials and molecular structures. An apparatus for identification and analysis of materials and molecular structures may include a laser. The laser may, in turn, include an amplified spontaneous emission-suppressed single-frequency laser excitation source. The apparatus may further comprise a plurality of filters. The plurality of filters may include reflective volume holographic grating blocking filters. The apparatus may also comprise an optical unit and an optical spectrometer. The optical unit may be configured to deliver excitation energy to a sample substance and capture Raman signal scattering from the sample substance. The optical spectrometer may be disposed in a path of the Raman signal and configured to measure a spectrum of the Raman signal and generate a detection signal. Finally, the apparatus may comprise a processing unit configured to analyze the spectrum.

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