BORESCOPE CALIBRATOR AND USER CHECK GAUGE

    公开(公告)号:US20170122879A1

    公开(公告)日:2017-05-04

    申请号:US14930069

    申请日:2015-11-02

    Abstract: A borescope calibration device is provided that includes a base having a planar surface and a plurality of reference surfaces on a side of the base opposing the planar surface, each of the plurality of reference surfaces having a height that decreases along a length of the base, a fixture that positions an optical head along a reference line that is parallel to the planar surface and providing a fixed distance between the reference surfaces and the optical head, the fixture being movable along a length of the base, and a target pattern formed on each of the reference surfaces.

    Sensor apparatus to determine a value of a chemical parameter based on a color shade and methods thereof
    42.
    发明授权
    Sensor apparatus to determine a value of a chemical parameter based on a color shade and methods thereof 有权
    用于基于色度确定化学参数的值的传感器装置及其方法

    公开(公告)号:US09568432B2

    公开(公告)日:2017-02-14

    申请号:US14497384

    申请日:2014-09-26

    Abstract: Apparatus and methods may provide for determining a value of chemical parameter. One or more light emitters may be positioned within a housing to emit light through an aperture of the housing. The emitted light may illuminate a color area of a structure that is separable from the housing, such as a test strip, a printed color reference, and so on. A color sensor may be positioned within the housing to capture reflected light and to convert the reflected light to an initial digitized color space that may be usable to determine a color shade of a color area. The reflected light may, for example, be captured independently at least of a dimension (e.g., predetermined size, shape, etc.) of the color area.

    Abstract translation: 装置和方法可以提供用于确定化学参数的值。 一个或多个光发射器可以定位在壳体内以通过壳体的孔发光。 发射的光可以照亮可与壳体分离的结构的颜色区域,例如测试条,印刷的颜色基准等。 颜色传感器可以定位在壳体内以捕获反射光并将反射光转换成可用于确定颜色区域的色调的初始数字化颜色空间。 反射光可以例如至少独立地捕捉颜色区域的尺寸(例如,预定尺寸,形状等)。

    RAMAN SPECTROSCOPY FOR BIOPROCESS OPERATIONS
    44.
    发明申请
    RAMAN SPECTROSCOPY FOR BIOPROCESS OPERATIONS 审中-公开
    拉曼光谱用于生物工作

    公开(公告)号:US20160341667A1

    公开(公告)日:2016-11-24

    申请号:US14989491

    申请日:2016-01-06

    Applicant: AbbVie, Inc.

    CPC classification number: G01N21/65 G01N33/6848 G01N33/6854 G01N2201/13

    Abstract: A method of characterizing a multi-component mixture for use in a bioprocess operation that includes providing a multi-component mixture standard with pre-determined amounts of known components; performing a Raman Spectroscopy analysis on the multi-component mixture standard; providing a multi-component test mixture from the bioprocess operation; performing a Raman Spectroscopy analysis on the multi-component test mixture; and comparing the analysis of the multi-component mixture standard and the multi-component test mixture to characterize the multi-component test mixture. In one embodiment, the multi-component mixture standard and the multi-component test mixture both comprise one or more of, at least two, at least three of, or each of, a polysaccharide (e.g. sucrose or mannitol), an amino acid (e.g., L-arginine, L-histidine or L-ornithine), a surfactant (e.g. polysorbate 80) and a pH buffer (e.g., a citrate formulation).

    Abstract translation: 一种表征用于生物过程操作的多组分混合物的方法,其包括提供具有预定量的已知组分的多组分混合物标准品; 对多组分混合物标准进行拉曼光谱分析; 从生物过程操作提供多组分测试混合物; 对多组分测试混合物进行拉曼光谱分析; 并比较多组分混合物标准品和多组分试验混合物的分析,以表征多组分试验混合物。 在一个实施方案中,多组分混合物标准品和多组分测试混合物都包含多糖(例如蔗糖或甘露糖醇),氨基酸(例如蔗糖或甘露醇)中的一种或多种,​​至少两种,至少三种, 例如L-精氨酸,L-组氨酸或L-鸟氨酸),表面活性剂(例如聚山梨酯80)和pH缓冲液(例如柠檬酸盐制剂)。

    CALIBRATION STANDARD FOR A DEVICE FOR IMAGE-BASED REPRESENTATION OF BIOLOGICAL MATERIAL
    45.
    发明申请
    CALIBRATION STANDARD FOR A DEVICE FOR IMAGE-BASED REPRESENTATION OF BIOLOGICAL MATERIAL 审中-公开
    用于基于图像代表生物材料的设备的校准标准

    公开(公告)号:US20160313249A1

    公开(公告)日:2016-10-27

    申请号:US15105480

    申请日:2014-12-09

    Abstract: The invention relates to a calibration standard (7) for a device (1) for image-based representation of biological material (6) which is excited to luminescence at least regionally during the examination. The device (1) has an illumination unit (2) comprising a radiation source, by which an electromagnetic excitation radiation (15) is emittable. Furthermore, a receptacle (3) is provided, which ensures that the biological material (6) arranged on a carrier (5) is positioned within a beam path of the excitation radiation (15). Moreover, the device has at least one image generating unit (4), which receives luminescence radiation (16) emitted by the biological material (6) on account of the excitation by the excitation radiation (15) and generates an image at least of the regions of the biological material (6) which are excited to luminescence. For calibration purposes, the device has a calibration standard (7), which emits a calibration radiation on account of the excitation by the excitation radiation (15), which calibration radiation is captured by the image generating unit (4), and a calibration signal is generatable in a controller (18) taking account of the captured calibration radiation. The technical solution described is distinguished by the fact that the calibration standard (7) has a housing (9) with, enclosed therein, a substance (12) which is excitable to luminescence, and is fixedly connected to the illumination unit (2) or the receptacle (3) with the aid of a fixing means (19).

    Abstract translation: 本发明涉及用于生物材料(6)的基于图像的表示的装置(1)的校准标准(7),其在检查期间至少在区域上被激发以发光。 设备(1)具有包括辐射源的照明单元(2),通过该辐射源可以发射电磁激发辐射(15)。 此外,设置容器(3),其确保布置在载体(5)上的生物材料(6)位于激发辐射(15)的光束路径内。 此外,该装置具有至少一个图像生成单元(4),其接收由于激发辐射(15)的激发而由生物材料(6)发射的发光辐射(16),并且至少产生图像 激发发光的生物材料(6)的区域。 为了校准目的,该装置具有校准标准(7),该校准标准(7)由于由图像生成单元(4)捕获的校准辐射的激发辐射(15)的激发而发出校准辐射,并且校准信号 在控制器(18)中可以考虑到所捕获的校准辐射。 描述的技术方案的特征在于校准标准(7)具有壳体(9),壳体(9)包围有可发光的物质(12),并固定地连接到照明单元(2)或 所述容器(3)借助于固定装置(19)。

    CORRECTION FOR OSMOTIC PRESSURE VARIATIONS IN CHEMO-OPTICAL SENSOR SPOTS
    46.
    发明申请
    CORRECTION FOR OSMOTIC PRESSURE VARIATIONS IN CHEMO-OPTICAL SENSOR SPOTS 有权
    化学传感器冲击波动压力变化的校正

    公开(公告)号:US20160116408A1

    公开(公告)日:2016-04-28

    申请号:US14893961

    申请日:2014-05-30

    Abstract: The present invention relates to a method for optically determining the concentration of a gas, using at least two luminescent dyes, the first being in-sensitive to the concentration of a gas with respect to the luminescence response (reference dye) and the second being sensitive to the concentration of a gas with respect to the luminescence response (indicator dye), wherein said dyes show different luminescence decay times so that the resultant phase angle is indicative for the concentration of a gas, characterized in that the detected luminescent amplitude of the reference dye at a first moment in time is utilized to correct for sensitivity changes after said moment. The present invention also relates to a corresponding method for quality assessment of the measurement of an optical sensor for determining the concentration of a gas.

    Abstract translation: 本发明涉及一种使用至少两种发光染料光学测定气体浓度的方法,其中第一种与气体的浓度对应于发光响应(参考染料)敏感,而第二种是敏感的 相对于发光响应(指示剂染料)的气体浓度,其中所述染料显示不同的发光衰减时间,使得所得到的相位角指示气体的浓度,其特征在于检测到的参考的发光振幅 利用第一时刻的染料来校正所述时刻之后的灵敏度变化。 本发明还涉及用于确定气体浓度的光学传感器的测量的质量评估的相应方法。

    CALIBRATION STANDARD WITH PRE-DETERMINED FEATURES
    47.
    发明申请
    CALIBRATION STANDARD WITH PRE-DETERMINED FEATURES 审中-公开
    具有预先确定的特征的校准标准

    公开(公告)号:US20160069929A1

    公开(公告)日:2016-03-10

    申请号:US14783403

    申请日:2013-04-17

    Abstract: Provided herein in an apparatus, including a substrate; a functional layer, wherein the functional layer has a composition characteristic of a workpiece of an analytical apparatus; and pre-determined features configured to calibrate the analytical apparatus. Also provided herein is an apparatus, including a functional layer overlying a substrate; and pre-determined features for calibration of an analytical apparatus configured to measure the surface of a workpiece, wherein the functional layer has a composition similar to the workpiece. Also provided herein is a method, including providing a lithographic calibration standard having a functional layer to an analytical apparatus, wherein the functional layer has a composition characteristic of a workpiece of the analytical apparatus; providing calibration standard specifications to a computer interfaced with the analytical apparatus; and calibrating the analytical apparatus in accordance with calibration standard readings and the calibration standard specifications.

    Abstract translation: 本文提供的装置包括基板; 功能层,其中所述功能层具有分析装置的工件的成分特征; 以及配置成校准分析装置的预定特征。 本文还提供了一种装置,包括覆盖衬底的功能层; 以及用于校准配置成测量工件表面的分析装置的预定特征,其中所述功能层具有类似于所述工件的组成。 本文还提供了一种方法,包括向分析装置提供具有功能层的光刻校准标准,其中功能层具有分析装置的工件的成分特征; 向与分析仪器连接的计算机提供校准标准规格; 并根据校准标准读数和校准标准规格校准分析仪器。

    METHOD OF INSPECTING FOREIGN SUBSTANCE ON SUBSTRATE
    48.
    发明申请
    METHOD OF INSPECTING FOREIGN SUBSTANCE ON SUBSTRATE 审中-公开
    检查基板上的外来物质的方法

    公开(公告)号:US20160025649A1

    公开(公告)日:2016-01-28

    申请号:US14781953

    申请日:2014-04-01

    Abstract: In order to inspect a substrate, an image information of a substrate before applying solder is displayed. Then, at least one inspection region on the substrate is image-captured to obtain an image of the inspection region that is image-captured. Then, image information that is to be displayed is renewed and the renewed image information is displayed. And, in order to inspect a foreign substance, obtained image of the inspection region is compared with a reference image of the substrate. Therefore, an operator can easily catch a region corresponding to a specific region of the image that is displayed, and easily detect a foreign substance on the substrate.

    Abstract translation: 为了检查基板,显示在施加焊料之前的基板的图像信息。 然后,对基板上的至少一个检查区域进行图像拍摄,以获得被图像捕获的检查区域的图像。 然后,更新要显示的图像信息,并显示更新的图像信息。 并且,为了检查异物,将获得的检查区域的图像与基板的参考图像进行比较。 因此,操作者可以容易地捕捉与所显示的图像的特定区域对应的区域,并容易地检测基板上的异物。

    Test method and test device for analysing a body fluid
    49.
    发明授权
    Test method and test device for analysing a body fluid 有权
    用于分析体液的测试方法和测试装置

    公开(公告)号:US09052293B2

    公开(公告)日:2015-06-09

    申请号:US13209708

    申请日:2011-08-15

    Abstract: There is provided a test method for analysing a body fluid in which a test tape is used in a test device in order to successively provide analytical test fields stored on the test tape, wherein body fluid is applied by a user to the test field provided at a time and the said test field is photometrically scanned using a measuring unit of the device to record measurement signals. In order to increase the measurement reliability, it is proposed that a control value is determined from a time-dependent and/or wavelength-dependent change in the measurement signals and that the measurement signals are processed as valid or discarded as erroneous depending on the control value.

    Abstract translation: 提供了一种用于分析在测试装置中使用测试带的体液的测试方法,以便连续提供存储在测试带上的分析测试领域,其中体液由用户施加到在 使用该装置的测量单元对所述测试场进行光度扫描以记录测量信号。 为了提高测量可靠性,提出根据测量信号的时间依赖性和/或波长相关的变化来确定控制值,并且根据控制值将测量信号处理为有效或丢弃为错误 值。

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