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    Surfactant-based monolithic columns, methods for making the same, and method for using the same
    51.
    发明授权
    Surfactant-based monolithic columns, methods for making the same, and method for using the same 有权
    基于表面活性剂的整体柱，其制备方法及其使用方法

    公开(公告)号：US08435410B2

    公开(公告)日：2013-05-07

    申请号：US12922357

    申请日：2009-03-30

    Applicant: Shahab Ahmed Shamsi ,  Congying Gu ,  Jun He

    Inventor： Shahab Ahmed Shamsi ,  Congying Gu ,  Jun He

    IPC: B01D15/08

    CPC classification number: C08J9/127 ,  B01J20/261 ,  B01J20/267 ,  B01J20/28042 ,  B01J20/285 ,  B01J2220/82 ,  G01N2030/528

    Abstract: A method for making a surfactant-based monolithic column is provided. The method comprises providing a mixture comprising at least one surfactant monomer, at least one crosslinker, at least one initiator, and at least one porogen and polymerizing the mixture to form the surfactant-based monolithic column. The present disclosure also provides a surfactant-based monolithic column, a method for separating molecules, and a process for preparing a surfactant monomer.

    Abstract translation: 提供了制备基于表面活性剂的整体柱的方法。 该方法包括提供包含至少一种表面活性剂单体，至少一种交联剂，至少一种引发剂和至少一种致孔剂的混合物，并使混合物聚合以形成基于表面活性剂的整体柱。 本公开还提供了一种基于表面活性剂的整体柱，分离分子的方法和制备表面活性剂单体的方法。

    Fluorocarbon mediated polymer blends and methods for making thereof
    55.
    发明授权
    Fluorocarbon mediated polymer blends and methods for making thereof 有权
    氟碳介导的聚合物共混物及其制备方法

    公开(公告)号：US08236902B2

    公开(公告)日：2012-08-07

    申请号：US11923522

    申请日：2007-10-24

    Applicant: Thieo Hogen-Esch ,  Jingguo Shen

    Inventor： Thieo Hogen-Esch ,  Jingguo Shen

    IPC: C08F8/24 ,  C08L23/28 ,  C09K11/06

    CPC classification number: C08F214/18 ,  B01J20/261 ,  B01J20/262 ,  B01J20/264 ,  B01J20/265 ,  B01J20/285 ,  C08F8/18 ,  C08J3/005 ,  C08L25/06 ,  C08L33/10 ,  C08L33/12 ,  Y10S525/931 ,  C08L2666/04

    Abstract: The present invention discloses a method for making blended polymers by utilizing fluorophilic inter-polymer associative interactions between perfluorocarbon functional groups attached on the constituent polymers. The method of the present invention is capable of forming blended polymers from otherwise incompatible polymers. Also disclosed are blended polymers obtained by the method thereof. Methods and devices utilizing novel blended polymer of the present invention including chromatography, catalysis, photonic and sensor applications are also provided.

    Abstract translation: 本发明公开了一种通过利用连接在构成聚合物上的全氟化碳官能团之间的氟亲和性聚合物缔合相互作用来制备共混聚合物的方法。 本发明的方法能够形成来自其它不相容聚合物的共混聚合物。 还公开了通过其方法获得的共混聚合物。 还提供了利用包括色谱法，催化，光子和传感器应用在内的本发明新型共混聚合物的方法和装置。

    Stable composite material comprising supported porous gels
    58.
    发明授权
    Stable composite material comprising supported porous gels 有权
    稳定的复合材料包括支撑的多孔凝胶

    公开(公告)号：US08133840B2

    公开(公告)日：2012-03-13

    申请号：US11628805

    申请日：2005-06-06

    Applicant: Alicja M. Mika ,  Maggie Sanju Wang ,  Ronald F. Childs

    Inventor： Alicja M. Mika ,  Maggie Sanju Wang ,  Ronald F. Childs

    IPC: B01J20/26

    CPC classification number: B01J20/28047 ,  B01J20/28033 ,  B01J20/28078 ,  B01J20/28085 ,  B01J20/28097 ,  B01J20/285 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3278 ,  B01J20/3282 ,  C12N5/0068 ,  C12N2533/30 ,  Y10S502/526

    Abstract: This invention relates to a stable composite material comprising a support member that has a plurality of pores extending through the support member, and a macroporous crosslinked gel that is located in, and fills, the pores of the support member, in which crosslinked gel is entrapped a stabilizing polymer, which stabilizing polymer is neutral, linear or branched, non-crosslinked, and substantially water-insoluble. The presence of the stabilizing polymer is such that it allows the composite material to largely retain its porosity and morphology after being dried. The invention also relates to a process for preparing the stable composite material described above, and to its use. The stable composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.

    Abstract translation: 本发明涉及一种稳定的复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件和位于并填充支撑构件的孔中并且填充有交联凝胶的孔的大孔交联凝胶 稳定聚合物，其稳定聚合物是中性的，直链或支链的，非交联的，基本上不溶于水的。 稳定聚合物的存在使得其允许复合材料在干燥后大大保持其孔隙率和形态。 本发明还涉及制备上述稳定复合材料及其用途的方法。 稳定的复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。

    Microfabricated gas chromatograph
    59.
    发明授权
    Microfabricated gas chromatograph 有权
    微型气相色谱仪

    公开(公告)号：US08132443B2

    公开(公告)日：2012-03-13

    申请号：US12434180

    申请日：2009-05-01

    Applicant: R Andrew McGill ,  Rekha Pai ,  David R. Mott ,  Jennifer L Stepnowski ,  Viet Nguyen

    Inventor： R Andrew McGill ,  Rekha Pai ,  David R. Mott ,  Jennifer L Stepnowski ,  Viet Nguyen

    IPC: B01D53/02

    CPC classification number: G01N30/6095 ,  B01J20/205 ,  B01J20/282 ,  B01J20/285 ,  B01J2220/54 ,  B01L3/502707 ,  B01L3/502746 ,  B01L2200/0689 ,  B01L2300/0816 ,  B01L2300/0883 ,  B01L2300/1827 ,  G01N2030/025

    Abstract: The present invention is generally directed to a microfabricated gas chromatograph column having two patterned substrates, each optionally having a stationary phase material coating, bonded together to provide a continuous flow channel. The flow channel can have a serpentine arrangement or a modified serpentine arrangement comprising alternating series of consecutive turns in one direction where each series has enough turns to move carrier gas and analyte molecules from the center of the column cross section to an outer wall of the channel or from one outer wall of the channel to the opposite outer wall. Different portions of the substrates can be coated with differing thicknesses of stationary phase material and/or with different stationary phase materials. The column can have a circular cross-section or a semi-circular cross-section where the flat portion of the cross-section has grooves. Also disclosed is the related method of making the microfabricated gas chromatograph column.

    Abstract translation: 本发明一般涉及一种具有两个图案化基底的微制造气相色谱柱，每个图案化基底可任选地具有固定相材料涂层，粘合在一起以提供连续的流动通道。 流动通道可以具有蛇形排列或修改的蛇形结构，其包括在一个方向上交替连续的连续匝数，其中每个系列具有足够的匝数以将载气和分析物分子从柱截面的中心移动到通道的外壁 或从通道的一个外壁到相对的外壁。 可以用不同厚度的固定相材料和/或用不同的固定相材料涂覆不同部分的基材。 该柱可以具有圆形横截面或半圆形横截面，其中横截面的平坦部分具有凹槽。 还公开了制造微细气相色谱仪柱的相关方法。

    HYDROPHOBIC MONOMERS, HYDROPHOBICALLY-DERIVATIZED SUPPORTS, AND METHODS OF MAKING AND USING THE SAME
    60.
    发明申请
    HYDROPHOBIC MONOMERS, HYDROPHOBICALLY-DERIVATIZED SUPPORTS, AND METHODS OF MAKING AND USING THE SAME 审中-公开
    疏水性单体，疏水性衍生物的支持物及其制备方法和使用方法

    公开(公告)号：US20120039920A1

    公开(公告)日：2012-02-16

    申请号：US13258018

    申请日：2010-03-19

    Applicant: Jerald K. Rasmussen ,  Cary A. Kipke ,  James I. Hembre ,  Peter D. Wickert

    Inventor： Jerald K. Rasmussen ,  Cary A. Kipke ,  James I. Hembre ,  Peter D. Wickert

    IPC: A61K39/00 ,  C08J9/00 ,  B05D5/00 ,  B05D7/24 ,  A61P37/04 ,  C07C237/22 ,  C07K1/20 ,  C12N9/00 ,  C07H1/06 ,  C08F22/38 ,  B05D3/00

    CPC classification number: B01J20/285 ,  B01D15/206 ,  B01D15/327 ,  B01D67/0006 ,  B01D67/0088 ,  B01D67/0093 ,  B01D69/125 ,  B01D71/56 ,  B01D2323/30 ,  B01D2325/38 ,  B01J20/286 ,  C07C237/22 ,  C08F20/54

    Abstract: A composition is disclosed comprising a hydrophobic monomer having the structure: CH2═CR4C(O)NHC(R1R1)(C(R1R1))nC(O)XR3 wherein n is an integer of 0 or 1; R1 is independently selected from at least one of: a hydrogen atom, alkyls aryls, and alkylaryls, wherein the alkyls, aryls, and alkylaryls have a total of 10 carbon atoms or less; R3 is a hydrophobic group selected from at least one of: alkyls, aryls, alkylaryls and ethers, wherein the alkyls, aryls, alkylaryls and ethers have a total number of carbon atoms ranging from 4 to 30; R4 H or CH3; X is O or NH. In some embodiments the hydrophobic monomer is derived from an amine or an alcohol (HXR3) that has a hydrophilicity index of 25 or less. A polymerizable composition comprising the hydrophobic monomer is disclosed, which optionally may comprise a cross-linking monomer and/or a non-cross-linking monomer. This polymerizable mixture may be used to from hydrophobically-derivatized supports, which may be used in applications such as hydrophobic interaction chromatography.

    Abstract translation: 公开了包含具有以下结构的疏水单体的组合物：CH 2 = CR 4 C（O）NHC（R 1 R 1）（C（R 1 R1））nC（O）XR 3，其中n为0或1的整数; R 1独立地选自氢原子，烷基芳基和烷基芳基中的至少一个，其中烷基，芳基和烷基芳基总共具有10个或更少的碳原子; R3是选自烷基，芳基，烷基芳基和醚中的至少一种的疏水基团，其中烷基，芳基，烷基芳基和醚的总碳原子数范围为4-30; R4 H或CH3; X是O或NH。 在一些实施方案中，疏水性单体衍生自亲水性指数为25以下的胺或醇（HXR3）。 公开了包含疏水单体的可聚合组合物，其任选地可以包含交联单体和/或非交联单体。 该可聚合混合物可用于疏水衍生的载体，其可用于例如疏水相互作用层析的应用中。

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