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    Stent crimping system
    62.
    发明授权
    Stent crimping system 有权
    支架压接系统

    公开(公告)号：US07628051B1

    公开(公告)日：2009-12-08

    申请号：US11752115

    申请日：2007-05-22

    Applicant: Arkady Kokish ,  David Lowe ,  Dan Shumer ,  Scott Baron

    Inventor： Arkady Kokish ,  David Lowe ,  Dan Shumer ,  Scott Baron

    IPC: B21D41/00

    CPC classification number: B25B27/10 ,  A61F2/95 ,  A61F2002/9522

    Abstract: A stent crimping apparatus is provided which includes a crimping assembly adapted to crimp the stent, a clamp assembly configured to secure the medical device; and a control unit configured to control the movement of the crimp assembly. The clamp assembly includes a lower clamp device defining a seating groove formed and dimensioned to seat a portion of the medical device therein, and a retaining assembly having an elastomeric member. This elastomeric member defines a contacting groove oriented in an opposed manner proximate to at least a portion of the seating groove. The clamp assembly further includes an actuation mechanism associated with the retaining assembly and the lower clamp device such that operation thereof causes the retaining assembly to move between an opened condition and a closed condition. In the opened condition, the medical device can be positioned between the lower clamp device and the retaining assembly, and in the closed condition, retaining the medical device between the contacting groove of the elastomeric member and the seating groove of the lower clamp device.

    Abstract translation: 提供一种支架压接装置，其包括适于卷曲支架的压接组件，构造成固定医疗装置的夹具组件; 以及控制单元，被配置为控制压接组件的运动。 夹具组件包括下夹具装置，该下夹具装置限定形成并定尺寸以将医疗装置的一部分安置在其中的安置槽，以及具有弹性构件的保持组件。 该弹性体构件限定了接近凹槽，该接触槽以相对的方式定位成接近于止动槽的至少一部分。 夹具组件还包括与保持组件和下夹具装置相关联的致动机构，使得其操作使得保持组件在打开状态和关闭状态之间移动。 在打开状态下，医疗装置可以位于下夹紧装置和保持组件之间，并且在关闭状态下，将医疗装置保持在弹性体构件的接触槽和下夹紧装置的安置槽之间。

    Machine for food waste densification and removal and process for same
    63.
    发明申请
    Machine for food waste densification and removal and process for same 审中-公开
    机器用于食品废物的致密化和去除加工

    公开(公告)号：US20090081013A1

    公开(公告)日：2009-03-26

    申请号：US12220562

    申请日：2008-07-25

    Applicant: David Lowe ,  Harry Vernon McGahey, JR.

    Inventor： David Lowe ,  Harry Vernon McGahey, JR.

    IPC: B65F3/04 ,  B65F3/14

    CPC classification number: B65F1/1452 ,  B30B9/301 ,  B30B9/3039 ,  B30B9/3042 ,  B65F3/02 ,  B65F3/08

    Abstract: A machine and process for commercial and industrial food waste densification and removal combining a leak proof trailer, a densification system, a trash container, and a dumping mechanism, into a unified collection apparatus. An organic waste generator such as a restaurant can easily store large amounts of its organic liquid and semi-liquid refuse and wastes onsite until the unit is full, then a trash hauler can transport this waste in the leak proof trailer to a municipal landfill or other processing location.

    Abstract translation: 将防泄漏拖车，致密化系统，垃圾容器和倾卸机构结合在一起的商业和工业食品废物致密化和去除的机器和方法进入统一收集装置。 诸如餐馆的有机废物产生器可以容易地将大量有机液体和半液体垃圾和废物在现场存储直到装置充满，然后垃圾运输机可以将这种废物在防漏拖车中运输到市政垃圾填埋场或其他 处理位置。

    Methods for determining the sequence of a peptide motif having affinity for a substrate
    66.
    发明申请
    Methods for determining the sequence of a peptide motif having affinity for a substrate 审中-公开
    确定对底物具有亲和力的肽基序的序列的方法

    公开(公告)号：US20060286047A1

    公开(公告)日：2006-12-21

    申请号：US11157661

    申请日：2005-06-21

    Applicant: David Lowe

    Inventor： David Lowe

    IPC: C40B30/02 ,  G01N33/53 ,  G06F19/00 ,  A61K8/65

    CPC classification number: A61K8/64 ,  A61K2800/94 ,  A61Q5/065 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  G01N33/6845

    Abstract: Disclosed herein are methods for determining peptide motifs having binding affinity for a specified substrate. The method proceeds through the analysis of a population of peptides having some affinity for a substrate for the identification of the presence of subsequences that occur statistically more frequently than by random chance. These subsequences are then assembled into motifs having reproducible strong binding affinity for the subject substrate.

    Abstract translation: 本文公开了确定对特定底物具有结合亲和力的肽基序的方法。 该方法通过分析具有对底物具有一定亲和性的肽群来分析，以鉴定存在统计学上比通过随机机会更频繁的子序列。 然后将这些亚序列组装成具有对受试底物的可重复的强结合亲和力的基序。

    Endoprosthesis having foot extensions
    67.
    发明授权
    Endoprosthesis having foot extensions 有权

    公开(公告)号：US07128756B2

    公开(公告)日：2006-10-31

    申请号：US10430644

    申请日：2003-05-06

    Applicant: David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard H. Huang ,  Anton G. Clifford ,  Kevin Kang

    Inventor： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard H. Huang ,  Anton G. Clifford ,  Kevin Kang

    IPC: A61F2/06

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0043 ,  A61F2230/0054

    Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.

    Endoprosthesis having foot extensions
    68.
    发明申请
    Endoprosthesis having foot extensions 有权

    公开(公告)号：US20060142844A1

    公开(公告)日：2006-06-29

    申请号：US11358279

    申请日：2006-02-21

    Applicant: David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard Huang ,  Anton Clifford ,  Kevin Kang

    Inventor： David Lowe ,  Erik Eli ,  Jeff Pappas ,  Howard Huang ,  Anton Clifford ,  Kevin Kang

    IPC: A61F2/90

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0043 ,  A61F2230/0054

    Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.

    Product removal process for use in a biofermentation system
    70.
    发明申请
    Product removal process for use in a biofermentation system 失效
    用于生物发酵系统的产品去除过程

    公开(公告)号：US20050208615A1

    公开(公告)日：2005-09-22

    申请号：US10860221

    申请日：2004-06-03

    Applicant: Antoinette Wilkins ,  David Lowe

    Inventor： Antoinette Wilkins ,  David Lowe

    IPC: C12M1/00 ,  B01D15/08 ,  C12M1/12 ,  C12M1/26 ,  C12N1/38 ,  C12P7/18 ,  C12P1/00 ,  C12P21/06

    CPC classification number: C12M47/12 ,  B01D15/1814 ,  B01D15/426 ,  C12M29/02 ,  C12M33/14 ,  C12M47/10 ,  C12N1/38 ,  C12P7/18

    Abstract: This invention relates to a bioprocess engineering solution for a product removal process for use in a biofermentation. The invention discloses a process for withdrawing an aliquot of broth from a biofermentation vessel during at least a portion of the biofermentation, removing biocatalyst and water, chromatographically separating biofermentation products from the withdrawn broth using water as an eluent, and returning the remaining components of the broth back to the biofermentation vessel. Process chromatography permits highly selective separation of the target molecule, preventing feedback inhibition of the biofermentation.

    Abstract translation: 本发明涉及用于在生物发酵中使用的产品去除方法的生物过程工程解决方案。 本发明公开了一种在至少一部分生物发酵过程中从生物发酵容器中取出等份的肉汤的方法，除去生物催化剂和水，使用水作为洗脱剂，使生物发酵产物与取出的肉汤色谱分离，并返回剩余组分 肉汤回到生物发酵罐。 过程色谱法允许目标分子的高度选择性分离，防止反应抑制生物发酵。

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