公开(公告)号：US12071419B2

公开(公告)日：2024-08-27

申请号：US17727788

申请日：2022-04-24

Applicant: Trevor Percival Castor

Inventor： Trevor Percival Castor

IPC: C07D311/80 ,  B01J3/04 ,  C07C37/50 ,  C07C37/74 ,  C07C39/19

CPC classification number: C07D311/80 ,  B01J3/04 ,  C07C37/50 ,  C07C37/74 ,  C07C39/19

Abstract: This invention is for improving the manufacturing pharmaceutical grade CBD and other cannabinoids following current Good Manufacturing Practices (cGMP) of the US FDA for use in clinical trials for CNS and other indications by the NIH and other researchers. The major cannabinoids in marijuana (Cannabis) and hemp originate from Cannabigerolic Acid (CBGA) present in the biomass of the plant. Plant enzymes that are specific to different strains of biomass converts CBGA to different carboxylic acids of cannabinoids including Cannabidiolic Acid (CBDA) and Δ9-Tetrahydrocannabinolic Acid (Δ9-THCA). These are relatively stable in the growing and fresh-cut plants. These are converted by thermal decarboxylation to Cannabidiol (CBD) and Δ9-Tetrahydrocannabinol (Δ9-THC), carbon dioxide and water. Cannabinoids can be manufactured by first heating the Cannabis biomass to convert carboxylic acids prior to extraction and purification. Alternatively, and preferably because of manufacturing cost and product stability, the carboxylic acids can be first extracted and purified. They can be utilized in the carboxylic acid form or stored in a stable manner until converted to cannabinoids for use in medicine. This invention provides an efficient method for their conversion utilizing a high-pressure reactor under inert conditions.

公开(公告)号：US12051600B2

公开(公告)日：2024-07-30

申请号：US17202370

申请日：2021-03-16

Applicant: Shao-Chi Liu

Inventor： Shao-Chi Liu

IPC: G05D27/02 ,  G05D16/00 ,  G05D23/19 ,  H01L21/67 ,  B01J3/04

CPC classification number: H01L21/67092 ,  G05D16/028 ,  G05D23/1919 ,  G05D27/02 ,  B01J3/04

Abstract: A material processing apparatus including a processing chamber, an external pressure source, a pressure reducer, a temperature regulator, and a controller is provided. The processing chamber has an internal space. The external pressure source is connected to the processing chamber to pressurize the internal space. The pressure reducer is connected to the processing chamber to depressurize the internal space. The temperature regulator is arranged in the processing chamber to adjust the temperature in the internal space. The controller is configured to control the external pressure source and the temperature regulator to respectively increase the temperature to a first predetermined temperature and the pressure to a first predetermined pressure, and to control the pressure in the processing chamber to rise continuously before the temperature in the processing chamber rises to the first predetermined temperature. An operating method of a material processing apparatus is further provided.

公开(公告)号：US20230415112A1

公开(公告)日：2023-12-28

申请号：US18243182

申请日：2023-09-07

Applicant: HRL Laboratories, LLC

Inventor： John H. MARTIN ,  Brennan D. YAHATA ,  Robert MONE

IPC: B01J3/02 ,  B22F9/04 ,  B01J3/04 ,  B22F9/02 ,  B22F1/052 ,  B22F1/054 ,  B01F33/40 ,  B01F35/60 ,  B01F35/71 ,  B01F35/221 ,  B01F35/75

CPC classification number: B01J3/02 ,  B22F9/04 ,  B01J3/04 ,  B22F9/02 ,  B22F1/052 ,  B22F1/054 ,  B01F33/401 ,  B01F35/602 ,  B01F35/711 ,  B01F35/2213 ,  B01F35/2215 ,  B01F35/7543 ,  B01F35/22161 ,  B22F1/056 ,  B22F2202/03 ,  B22F2202/01 ,  B22F2301/058 ,  B22F2301/10 ,  B22F2301/15 ,  B22F2301/205 ,  B22F2301/255 ,  B22F2301/30 ,  B22F2301/35 ,  B22F2301/40 ,  B22F2302/05 ,  B22F2302/10 ,  B22F2302/20 ,  B22F2302/256 ,  B22F2303/20 ,  B22F2998/10 ,  B22F2999/00 ,  B82Y30/00

Abstract: Some variations provide a system for producing a functionalized powder, comprising: an agitated pressure vessel; first particles and second particles contained within the agitated pressure vessel; a fluid contained within the agitated pressure vessel; an exhaust line for releasing the fluid from the agitated pressure vessel; and a means for recovering a functionalized powder containing the second particles disposed onto surfaces of the first particles. A preferred fluid is carbon dioxide in liquefied or supercritical form. The carbon dioxide may be initially loaded into the pressure vessel as solid carbon dioxide. The pressure vessel may be batch or continuous and is operated under reaction conditions to functionalize the first particles with the second particles, thereby producing a functionalized powder, such as nanofunctionalized metal particles in which nanoparticles act as grain refiners for a component ultimately produced from the nanofunctionalized metal particles. Methods for making the functionalized powder are also disclosed.

公开(公告)号：US20230390442A1

公开(公告)日：2023-12-07

申请号：US18033228

申请日：2021-10-22

Applicant: Universidade de Santiago de Compostela

Inventor： Carlos Alberto Garcia Gonzalez ,  Víctor Santos Rosales ,  Maria Beatriz Magariños Ferro ,  Carmen Alvarez Lorenzo

IPC: A61L2/18 ,  A61L2/07

CPC classification number: A61L2/186 ,  A61L2/07 ,  B01J3/04

Abstract: A system for implantation by sterilisation techniques. A sterile implantation system comprising a heat-sensitive polymeric matrix that modifies its structure in the presence of a compressed gas or supercritical fluid to produce a solid or semi-solid with porosity greater than 60%.

公开(公告)号：US11834620B2

公开(公告)日：2023-12-05

申请号：US17527608

申请日：2021-11-16

Applicant: The Hong Kong University of Science and Technology

Inventor： Charles Wang Wai Ng ,  Sina Baghbanrezvan

IPC: B01J3/04 ,  C10L3/10 ,  B01J19/18

CPC classification number: C10L3/108 ,  B01J3/04 ,  B01J19/1806 ,  B01J2219/00069

Abstract: Systems and methods related to centrifuge energy harvesting chambers (CEHCs) for gas production simulation are provided. Certain CEHCs may include a high-pressure chamber, high-pressure syringe pumps, cooling systems, an actuator and surcharge, backpressure control inside the wellbore, a heating element on the wellbore, water gas separation systems, and flow measurement systems. Certain CEHCs may also provide software operably connected to sensors and instrumentation, comprising a module to continuously, in real-time, periodically, or asynchronously, measure and monitor simulation variables.

公开(公告)号：US20180334630A1

公开(公告)日：2018-11-22

申请号：US15983479

申请日：2018-05-18

Applicant: ACTIVE ENERGY GROUP PLC

Inventor： Philip J. Scalzo ,  Carleton D. Tait ,  Daniel J. McCarthy ,  Russell N. Taylor ,  Ronald A. Cella ,  Gregory W. Koch ,  David T. Morby ,  Jason W. Hepworth ,  Jason D. Owens

IPC: C10L5/44 ,  C10L5/36

CPC classification number: C10L5/442 ,  B01J3/04 ,  B01J8/0065 ,  B01J2208/0084 ,  B01J2219/00162 ,  C10L5/363 ,  C10L5/445 ,  C10L9/08 ,  C10L2290/02 ,  C10L2290/06 ,  C10L2290/08 ,  C10L2290/30 ,  C10L2290/46 ,  C10L2290/48 ,  C10L2290/50 ,  C10L2290/52 ,  C10L2290/545

Abstract: A process for cleaning and beneficiating biomass is described which may allow removal of entrained salts and light volatiles from biomass materials. The process may also minimize energy use through capturing steam and flue gases for re-use. The process may generally comprise the following steps: prewashing and/or preheating a biomass, pressurizing the biomass in a steam explosion vessel, rapidly depressurizing the steam explosion vessel, releasing the steam from the steam explosion vessel entrained with fine lignin-enriched particles into a cyclone-type gas expansion vessel, routing the steam from the gas expansion vessel to the input hopper, subjecting the biomass to a second washing step, mechanically removing a portion of the water from the biomass. After the biomass has been steam-exploded, it may be washed and used as an engineered soil.

公开(公告)号：US10035118B2

公开(公告)日：2018-07-31

申请号：US13506590

申请日：2012-04-30

Applicant: Ted Sand ,  David Chau ,  Matthew R. DeWitt ,  Sujata Ghosh ,  Kevin Hao-Yu Lin

Inventor： Ted Sand ,  David Chau ,  Matthew R. DeWitt ,  Sujata Ghosh ,  Kevin Hao-Yu Lin

IPC: A61M5/178 ,  B01J3/04 ,  A61B10/02 ,  A61M1/00 ,  A61M5/00 ,  A61M5/315 ,  A61M27/00

CPC classification number: B01J3/04 ,  A61B10/0283

Abstract: A system and method for isolating and separating lipoaspirate particles. The system includes a generally cylindrical container having a lid and a bottom wherein the container includes at least one input port positioned to permit a lipoaspirate fluid to enter the container above the bottom; and a source of a vacuum coupled to the container to provide a partial vacuum during use of the system.

公开(公告)号：US20180134824A1

公开(公告)日：2018-05-17

申请号：US15574310

申请日：2016-06-30

Applicant: Dow Global Technologies LLC

Inventor： Christopher R. Eddy ,  Jeffery S. Bradley ,  Otto J. Berbee ,  Sarat Munjal ,  Bryan Gutermuth

IPC: C08F210/02 ,  B01J3/04

CPC classification number: C08F210/02 ,  B01J3/00 ,  B01J3/04 ,  B01J3/042 ,  Y02P20/582 ,  C08F2/01 ,  C08F220/06

Abstract: A process to form an ethylene-based polymer comprising, in polymerized form, ethylene and at least one acid comonomer, said process comprising polymerizing a reaction mixture comprising the ethylene and the acid comonomer, in a reactor configuration comprising at least one Secondary compressor, at least one pressurization device, and at least one reactor selected from the following: at least one autoclave reactor, at least one tubular reactor, or a combination thereof; and wherein the reaction mixture is polymerized in the presence of at least one free-radical initiator, and at a pressure of at least 1000 Bar; and wherein at least a portion of a comonomer composition comprising at least a portion of the acid comonomer used in the polymerization, is compressed, to form a compressed comonomer composition, in the pressurization device, up to a discharge pressure ranging from 1000 Bar to 4000 Bar, and at a discharge temperature (DT) from 10 C to 100 C; and wherein the compressed comonomer composition bypasses the Secondary compressor, and is fed, downstream from the Secondary compressor, into the reactor, and/or into one or more feed streams to the reactor.

公开(公告)号：US09896740B2

公开(公告)日：2018-02-20

申请号：US14370841

申请日：2012-12-27

Applicant: SUMITOMO METAL MINING CO., LTD.

Inventor： Satoshi Matsubara ,  Osamu Nakai ,  Yoji Kyoda ,  Takashi Sakamoto

IPC: C22B3/00 ,  C22B3/02 ,  C22B3/04 ,  B01J3/04 ,  B01J4/00

CPC classification number: C22B23/0415 ,  B01J3/04 ,  B01J4/008 ,  B01J2219/00182 ,  C22B3/02 ,  C22B3/04 ,  Y02P10/234

Abstract: The present invention is such that, with H1 being the height from a slurry outlet to a control liquid level, H2 being the height from the control liquid level to the top of a flash vessel, and being the diameter of the flash vessel, 0.35D≦H1≦0.45D, and 0.75D≦H2≦0.85D, and at least one liquid level sensor detects a slurry liquid surface at a control liquid level; when the liquid level sensor detects a slurry liquid surface which has risen, a slurry discharge valve installed on a slurry discharge pipe derived from the flash vessel is opened; and when the liquid level sensor detects a slurry liquid surface which has fallen, the slurry discharge valve is closed, whereby opening and closing of the valve is appropriately controlled thereby to reduce troubles with a steam discharge pipe, the slurry discharge pipe, and the slurry discharge valve.

公开(公告)号：US09850217B2

公开(公告)日：2017-12-26

申请号：US15123924

申请日：2015-03-09

Applicant: Casale SA

Inventor： Enrico Rizzi

IPC: C07D251/60 ,  C07D251/62 ,  B01J19/24 ,  B01J3/04 ,  B01J10/00 ,  B01J4/00 ,  B01J3/02

CPC classification number: C07D251/60 ,  B01J3/02 ,  B01J3/04 ,  B01J3/042 ,  B01J4/002 ,  B01J10/005 ,  B01J19/246 ,  B01J2219/00078 ,  B01J2219/00081 ,  C07D251/62

Abstract: Reactor for the synthesis of melamine from urea, in accordance with the high-pressure non-catalytic process, comprising: a vertical reactor body (1), at least one inlet (2) for the urea melt, a set of heating elements (3), and a central duct (7), said set of heating elements (3) being arranged inside said central duct.