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公开(公告)号：US20240110837A1
公开(公告)日：2024-04-04
申请号：US18376582
申请日：2023-10-04
Applicant: California Institute of Technology , TotalEnergies OneTech
Inventor： Axel SCHERER , Jack JEWELL , John Richard ORDONEZ-VARELA , Paromita MITCHELL
IPC: G01K11/125
CPC classification number: G01K11/125
Abstract: A temperature monitoring system includes a semiconductor member mounted onto the surface of an object having a surface whose temperature is to be monitored. The semiconductor member has a temperature-dependent bandgap with an absorption edge that varies with temperature. A light source is configured to illuminate the semiconductor member with monochromatic light. The monochromatic light has a wavelength equal to an absorption edge wavelength that is associated with the absorption edge when the semiconductor member is at a specified temperature. A detector is configured to receive light reflected from the semiconductor member when illuminated with the monochromatic light such that a surface temperature of the object is at the specified temperature when a change in an amount of reflected light that is received indicates that the wavelength of the monochromatic light is equal to the absorption edge wavelength at the specified temperature.
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公开(公告)号：US20220170793A1
公开(公告)日：2022-06-02
申请号：US17675575
申请日：2022-02-18
Applicant: California Institute of Technology
Inventor： Axel SCHERER , Taeyoon JEON
Abstract: An infrared spectrometer for operation in the mid-infrared spectral range is presented, where the spectrometer includes a Bragg-mirror-based spectral filter that is operative for providing an interrogation signal whose spectral content is dispersed along a first direction at a filter aperture. The filter aperture is imaged through a sample by a thermal-imaging camera to create a focused image that is based on the interrogation signal and the absorption characteristics of the sample. As a result, embodiments in accordance with the present disclosure can be smaller, less complex, and less expensive than infrared spectrometers known in the prior art.
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公开(公告)号：US20210373208A1
公开(公告)日：2021-12-02
申请号：US17335946
申请日：2021-06-01
Applicant: California Institute of Technology
Inventor： Axel SCHERER , Taeyoon JEON
Abstract: The teachings of the present disclosure enable a reduction of the refractive index of a material by incorporating an additive selected from air, vacuum, or an inert gas in the material to turn the material into a material foam that is suitable for use in optical systems. A material foam in accordance with the present disclosure is characterized by a porosity that reduces its refractive index from that of the same material as found in nature. The higher porosity also decreases the density of the material from that of the same material as found in nature. Material foams in accordance with the present disclosure are suitable for use in the low-refractive-index layers of a Bragg mirror.
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公开(公告)号：US20210321918A1
公开(公告)日：2021-10-21
申请号：US17314930
申请日：2021-05-07
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Samson CHEN , Axel SCHERER , Dvin ADALIAN , Peter PETILLO , Muhammad Musab JILANI , Xiomara L. MADERO , Deepan KISHORE KUMAR
IPC: A61B5/1486 , C12N11/02 , C12N9/02 , A61B5/145 , A61B5/1459 , G01N27/327 , C12N11/14
Abstract: A sensor implanted in tissues and including a sensing layer is fabricated by mixing the signal transduction enzyme with non-reactive components including buffer salts and fillers, and spin coating the enzyme onto a substrate. The signal transduction enzyme is crosslinked by introducing the coated substrate in a vacuum chamber. In the chamber, a crosslinker evaporates and is deposited onto the enzyme, therefore crosslinking the enzyme.
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公开(公告)号：US20200249091A1
公开(公告)日：2020-08-06
申请号：US16782674
申请日：2020-02-05
Applicant: California Institute of Technology
Inventor： Axel SCHERER , Taeyoon JEON
Abstract: An infrared spectrometer for operation in the mid-infrared spectral range is presented, where the spectrometer includes a Bragg-mirror-based spectral filter that is operative for providing an interrogation signal whose spectral content is dispersed along a first direction at a filter aperture. The filter aperture is imaged through a sample by a thermal-imaging camera to create a focused image that is based on the interrogation signal and the absorption characteristics of the sample. As a result, embodiments in accordance with the present disclosure can be smaller, less complex, and less expensive than infrared spectrometers known in the prior art.
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Patent Agency Ranking
公开(公告)号：US20200216155A1
公开(公告)日：2020-07-09
申请号：US16719371
申请日：2019-12-18
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Emil P. KARTALOV , Axel SCHERER
Abstract: Methods to build implantable micro-sensors used to detect tissue-dissolved inert gas and to detect microbubble formation to avoid Caisson disease are described. The disclosed methods and devices are based on measuring physical changes in hydrophobic liquids after absorbing an inert gas such as nitrogen. The teachings of the disclosure help improve safety and efficiency of diving operations.
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公开(公告)号：US20200041508A1
公开(公告)日：2020-02-06
申请号：US16598433
申请日：2019-10-10
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Axel SCHERER , Samuel NJOROGE , Jingqing HUANG
IPC: G01N33/566 , A61B5/1459 , G01N33/543 , G01N21/41 , G01N33/552
Abstract: An implantable diagnostic device in accordance with the present disclosure provides various benefits such as a compact size thereby allowing implanting of the device inside animate objects; low cost due to incorporation of inexpensive detection circuitry and the use of conventional IC fabrication techniques; re-usability by heating thereby allowing multiple diagnostic tests to be performed without discarding the device; and a configuration that allows performing of simultaneous and/or sequential diagnostic tests for detecting one or more similar or dissimilar target molecules concurrently or at different times.
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68.发明申请公开(公告)号：US20190126228A1
公开(公告)日：2019-05-02
申请号：US16222865
申请日：2018-12-17
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Sameer WALAVALKAR , Axel SCHERER
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
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公开(公告)号：US20180267012A1
公开(公告)日：2018-09-20
申请号：US15913704
申请日：2018-03-06
Applicant: California Institute of Technology
Inventor： Axel SCHERER
IPC: G01N33/483 , A61F13/00 , G01N27/414 , A61B5/00
CPC classification number: G01N33/4836 , A61B5/0531 , A61B5/445 , A61B5/4848 , A61B5/6833 , A61F13/00051 , G01N27/4148
Abstract: A sensing chip attached to a bandage monitors the healing process of a wound by detecting growth factors, thrombin and fibrinogen. The complementary metal-oxide semiconductor includes a functionalized working electrode, functionalized counter electrode and functionalized reference electrode. The healing progress is stimulated by generating oxygen in the wound.
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公开(公告)号：US20180052110A1
公开(公告)日：2018-02-22
申请号：US15701014
申请日：2017-09-11
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Imran R. MALIK , Xiomara Linnette MADERO , Erika F. GARCIA , Sheel Mukesh SHAH , Axel SCHERER
CPC classification number: G01N21/6486 , C12Q1/6851 , C12Q2537/143 , C12Q2537/165 , C12Q2565/629
Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
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