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71.发明申请Method of fabricating an implantable medical device to reduce chance of late inflammatory response 有权制造可植入医疗器械以减少炎症反应迟发的方法公开(公告)号：US20070253999A1
公开(公告)日：2007-11-01
申请号：US11444596
申请日：2006-05-31
Applicant: Bin Huang , David Gale
Inventor： Bin Huang , David Gale
IPC: A61F2/06
CPC classification number: A61L31/06 , A61F2/915 , A61L31/148 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29B13/02 , B29C71/0063 , B29L2031/7532 , C08L67/04
Abstract: The invention provides a method for fabricating an implantable medical device to increase biocompatibility of the device, the method comprising: heat setting a polymer construct, wherein the polymer construct is at a temperature range of from about Tg to about 0.6(Tm−Tg)+Tg such that the set polymer construct comprises a crystalline structure having crystals at a size less than about 2 microns; and fabricating an implantable medical device from the heat set polymer construct.
Abstract translation: 本发明提供一种用于制造可植入医疗装置以提高装置的生物相容性的方法，所述方法包括：热定形聚合物构造物，其中所述聚合物构造物的温度范围为约Tg至约0.6（Tm-Tg）+ Tg使得所述聚合物构件包含具有小于约2微米尺寸的晶体的晶体结构; 以及从所述热固性聚合物构造物制造可植入医疗装置。
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72.发明申请Method of fabricating an implantable medical device using gel extrusion and charge induced orientation 审中-公开使用凝胶挤出和电荷诱导取向制造可植入医疗器械的方法公开(公告)号：US20070179219A1
公开(公告)日：2007-08-02
申请号：US11345073
申请日：2006-01-31
Applicant: Bin Huang , David Gale
Inventor： Bin Huang , David Gale
IPC: C08L1/10
CPC classification number: A61F2/82 , A61F2210/0004 , A61F2240/001 , A61F2250/0067 , A61L31/042 , A61L31/06 , A61L31/148 , B23K2103/42 , B23K2103/50 , C08L5/08 , C08L67/04
Abstract: The invention provides a method of manufacturing an implantable medical device, the method comprising: (a) disposing a polymer fluid comprising a solvent and a matrix polymer into a forming apparatus for forming a polymeric part; (b) cooling the formed polymeric part upon removal from the apparatus, the cooled polymeric part comprises the polymer and a substantial portion of the solvent from the polymer fluid; and (c) fabricating an implantable medical device from the cooled polymeric part.
Abstract translation: 本发明提供了一种制造可植入医疗装置的方法，该方法包括：（a）将包含溶剂和基质聚合物的聚合物流体置于用于形成聚合物部分的成形装置中; （b）在从装置上取出后冷却形成的聚合物部分，冷却的聚合物部分包含聚合物和大部分来自聚合物流体的溶剂; 和（c）从冷却的聚合物部件制造可植入医疗装置。
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公开(公告)号：US20060047336A1
公开(公告)日：2006-03-02
申请号：US10927601
申请日：2004-08-25
Applicant: David Gale , Klaus Kleine , Anthony Abbate , Svava Atladottir , Bin Huang
Inventor： David Gale , Klaus Kleine , Anthony Abbate , Svava Atladottir , Bin Huang
IPC: A61F2/06
CPC classification number: A61F2/958 , A61F2002/30062 , A61F2002/30448 , A61F2002/9522 , A61F2002/9583 , A61F2210/0004 , A61F2220/005
Abstract: Medical assemblies with a releasable connection and methods of constructing such medical assemblies are disclosed. The medical assemblies generally comprise a stent, a catheter assembly having catheter body a balloon, and a releasable connection between the stent and the catheter assembly that releases the stent from the catheter assembly in response to enlargement of the balloon or when the balloon has been enlarged to an expanded configuration.
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公开(公告)号：US09188558B2
公开(公告)日：2015-11-17
申请号：US12796546
申请日：2010-06-08
Applicant: Abigail Freeman , David C. Gale , Bin Huang , Daniel Castro
Inventor： Abigail Freeman , David C. Gale , Bin Huang , Daniel Castro
CPC classification number: G01N25/72 , A61B90/90 , A61B90/98 , A61F2/06 , A61F2/82 , A61F2250/0085 , A61L2/081 , A61L2/082 , A61L2/085 , A61L2/087 , A61L2/10 , A61L2202/14
Abstract: A method and system of monitoring environmental exposure of stents using radiofrequency identification is disclosed.
Abstract translation: 公开了使用射频识别来监测支架的环境暴露的方法和系统。
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公开(公告)号：US08940037B2
公开(公告)日：2015-01-27
申请号：US13281286
申请日：2011-10-25
Applicant: Bin Huang , David C. Gale
Inventor： Bin Huang , David C. Gale
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/9155 , A61F2210/0057 , A61F2250/001 , A61F2250/0029 , A61F2250/0036 , A61F2250/0071 , A61L31/06 , A61L31/14 , C08L67/04
Abstract: Disclosed is a method of treating a bodily lumen with a stent, the method comprising: disposing a stent within a bodily lumen, the stent comprising a plurality of deformable struts that are substantially circumferentially aligned and are configured to selectively deform in a circumferential direction in localized regions in the struts upon application of an outward radial force; and expanding the stent by applying the outward radial force, wherein the outward radial force causes selective deformation of the deformable struts in a localized region in the struts.
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Patent Agency Ranking
公开(公告)号：US08925177B2
公开(公告)日：2015-01-06
申请号：US13551538
申请日：2012-07-17
Applicant: Bin Huang , David C. Gale , Daniel Castro
Inventor： Bin Huang , David C. Gale , Daniel Castro
CPC classification number: A61F2/958 , A61F2002/9505 , A61F2002/9522 , A61F2002/9583 , A61F2002/9586 , B23P11/005 , Y10T29/49863 , Y10T29/49913 , Y10T29/49925 , Y10T29/49927 , Y10T29/53065 , Y10T29/53987
Abstract: A method of crimping a stent on a balloon of a catheter assembly is provided. A polymeric stent is disposed over a balloon in an inflated configuration. The stent is crimped over the inflated balloon to a reduced crimped configuration so that the stent is secured onto the balloon. The balloon wall membrane is wedged or pinched between the strut elements of the stent for increasing the retention of the stent on the balloon.
Abstract translation: 提供了一种将支架卷曲在导管组件的球囊上的方法。 将聚合物支架设置在膨胀构型的气球上。 将支架卷曲在膨胀的气囊上以减小卷曲构造，使得支架固定在气球上。 球囊壁膜被楔入或夹在支架的支柱元件之间，以增加支架在气囊上的保留。
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77.发明授权Method of fabricating an implantable medical device to reduce chance of late inflammatory response 有权制造可植入医疗器械以减少炎症反应迟发的方法公开(公告)号：US08747879B2
公开(公告)日：2014-06-10
申请号：US11444596
申请日：2006-05-31
Applicant: Bin Huang , David C. Gale
Inventor： Bin Huang , David C. Gale
CPC classification number: A61L31/06 , A61F2/915 , A61L31/148 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29B13/02 , B29C71/0063 , B29L2031/7532 , C08L67/04
Abstract: The invention provides a method for fabricating an implantable medical device to increase biocompatibility of the device, the method comprising: heat setting a polymer construct, wherein the polymer construct is at a temperature range of from about Tg to about 0.6(Tm−Tg)+Tg such that the set polymer construct comprises a crystalline structure having crystals at a size less than about 2 microns; and fabricating an implantable medical device from the heat set polymer construct.
Abstract translation: 本发明提供一种用于制造可植入医疗装置以提高装置的生物相容性的方法，所述方法包括：热定形聚合物构造物，其中所述聚合物构造物的温度范围为约Tg至约0.6（Tm-Tg）+ Tg使得所述聚合物构件包含具有小于约2微米尺寸的晶体的晶体结构; 以及从所述热固性聚合物构造物制造可植入医疗装置。
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公开(公告)号：US08741201B2
公开(公告)日：2014-06-03
申请号：US12878937
申请日：2010-09-09
Applicant: Bin Huang , David C. Gale
Inventor： Bin Huang , David C. Gale
CPC classification number: A61F2/915 , A61F2/04 , A61F2/06 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/91508 , A61F2002/91575 , A61F2210/0004 , A61F2210/0009 , A61F2210/0076 , A61F2220/005 , A61F2230/0013 , A61F2250/0098 , A61L31/129 , B23K26/402 , B23K26/50 , B23K2103/42 , B23K2103/50 , B29C43/02 , B29C45/0001 , B29C45/0005 , B29C45/0055 , B29C47/0004 , B29C47/0023 , B29C47/0026 , B29C47/0066 , B29C47/06 , B29C47/1045 , B29C53/566 , B29C53/583 , B29C59/02 , B29C59/021 , B29C2043/028 , B29K2101/00 , B29K2105/12 , B29K2267/043 , B29K2995/0056 , B29K2995/006 , B29L2023/003 , B29L2031/7546 , D03D3/02
Abstract: Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.
Abstract translation: 公开了用纤维增强的用于植入体腔的聚合复合支架。
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公开(公告)号：US08709071B1
公开(公告)日：2014-04-29
申请号：US11864472
申请日：2007-09-28
Applicant: Bin Huang , David C. Gale , Daniel A. Castro , Vincent J. Gueriguian
Inventor： Bin Huang , David C. Gale , Daniel A. Castro , Vincent J. Gueriguian
IPC: A61F2/06
CPC classification number: A61L31/10 , A61F2/86 , A61F2240/001 , A61F2250/0051 , A61F2250/0067 , A61K31/436 , A61L31/022 , A61L31/06 , A61L31/08 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2420/02 , A61L2420/08 , B05D1/02 , B05D1/18 , B05D1/32
Abstract: This invention relates to stents, a type of implantable medical device, with an antiproliferative coating and a prohealing luminal coating and methods of fabricating stents with an antiproliferative coating and a prohealing luminal coating.
Abstract translation: 本发明涉及支架，一种可植入医疗装置，其具有抗增殖性涂层和预呼流道腔涂层，以及制造具有抗增殖性涂层和预呼流道涂层的支架的方法。
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80.发明授权公开(公告)号：US08663192B2
公开(公告)日：2014-03-04
申请号：US12768628
申请日：2010-04-27
Applicant: Jerome E. Hester , Anthony J. Abbate , Richard E. Kaufman , David C. Gale , Gail M. Zaler , Bin Huang , Lisa Earnhardt , Vijaykumar Rajasekhar
Inventor： Jerome E. Hester , Anthony J. Abbate , Richard E. Kaufman , David C. Gale , Gail M. Zaler , Bin Huang , Lisa Earnhardt , Vijaykumar Rajasekhar
IPC: A61M31/00
CPC classification number: A61L31/16 , A61B17/04 , A61B17/06166 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/08 , A61B17/083 , A61B17/26 , A61B17/3468 , A61B2017/0073 , A61B2017/00893 , A61B2017/06176 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2090/3987 , A61B2090/3991 , A61L17/10 , A61M31/00 , A61M31/002 , A61M37/0069
Abstract: Described here are devices and methods for treating one or more conditions or symptoms associated with a tonsil procedure. In some variations, a drug-releasing device may be at least partially delivered to one or more tonsillar tissues before, during, or after a tonsil procedure. In some variations, the drug-releasing device may be configured to be biodegradable. In other variations, the drug-releasing device may comprise one or more hemostatic materials or one or more adhesives. The drug-releasing device may be configured to release one or more drugs or agents, such as, for example, one or more analgesics, local anesthetics, vasoconstrictors, antibiotics, combinations thereof and the like.
Abstract translation: 这里描述了用于治疗与扁桃体过程相关的一种或多种病症或症状的装置和方法。 在一些变型中，药物释放装置可以在扁桃体手术之前，期间或之后至少部分递送至一个或多个扁桃体组织。 在一些变型中，药物释放装置可以被配置为可生物降解的。 在其它变型中，药物释放装置可以包括一种或多种止血材料或一种或多种粘合剂。 药物释放装置可以被配置为释放一种或多种药物或药剂，例如一种或多种止痛剂，局部麻醉剂，血管收缩剂，抗生素及其组合等。
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