-
公开(公告)号:US10799870B2
公开(公告)日:2020-10-13
申请号:US15910641
申请日:2018-03-02
Applicant: Gen-Probe Incorporated
Inventor: Byron J. Knight , Vincent Chabot
Abstract: An insert for a liquid-holding container may include a body comprising a wall, open first and second ends, and a lumen extending from the open first end to the open second end. The insert also may include a plurality of first openings formed in the wall, the first openings being situated between the first and second ends, and each of the first openings defining an area, and one or more second openings formed in the wall, the one or more second openings being situated between the first and second ends, each of the one or more second openings defining an area that is greater than the area defined by any of the first openings, where at least one of the one or more second openings is situated closer to the first end than any of the first openings, and wherein each of the first and second openings is sized to permit the passage of a liquid.
-
公开(公告)号:US10443935B2
公开(公告)日:2019-10-15
申请号:US15745834
申请日:2016-08-02
Applicant: GEN-PROBE INCORPORATED
Inventor: Byron J. Knight
Abstract: A lyophilization nest and method of using the same is described herein. In various embodiments, the lyophilization nest is configured to support one or more receptacles each supporting one or more substances within an interior space of the lyophilization nest. The interior space may be in fluid communication with the exterior of the lyophilization nest through one or more vent holes extending through a surface of the lyophilization nest. Each of the one or more vent holes have a corresponding sealing element configured to selectively form an air-tight seal within the vent holes, such that a controlled environment may be maintained within the interior space when the ambient conditions surrounding the lyophilization nest are not lyophilization conditions. The one or more sealing elements may be operable while the lyophilization nest is positioned within a sealed lyophilizer by depressing the sealing elements into corresponding vent holes to form the air-tight seal.
-
公开(公告)号:US10159981B2
公开(公告)日:2018-12-25
申请号:US14992663
申请日:2016-01-11
Applicant: GEN-PROBE INCORPORATED
Inventor: Byron J. Knight
IPC: B01L99/00 , B01L3/00 , B65B69/00 , G01N35/10 , B65D39/00 , G01N35/02 , C12Q1/686 , B65D1/02 , B65D1/34 , B65D1/36 , B65D17/50 , G01N35/00 , G01N30/60
Abstract: A plastic body including a generally cylindrical upper portion having an open end configured for engagement with an automated pipettor. The plastic body further includes a plurality of longitudinally oriented ribs disposed on an inner surface of the open end of the upper portion and a plurality of concave recesses disposed on an outer surface of the upper portion. Each of the recesses is disposed directly opposite an associated one of the ribs, and each of the recesses extends along at least part of the length of the associated rib.
-
公开(公告)号:US10065190B2
公开(公告)日:2018-09-04
申请号:US15604791
申请日:2017-05-25
Applicant: GEN-PROBE INCORPORATED
Inventor: David Buse , Byron J. Knight , Julian Groeli
IPC: B01L3/00 , B65D1/34 , B65D1/02 , B65D39/00 , B65B69/00 , G01N35/02 , G01N35/10 , G01N30/60 , G01N35/00 , C12Q1/686
Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
-
公开(公告)号:US09726607B2
公开(公告)日:2017-08-08
申请号:US14195793
申请日:2014-03-03
Applicant: Gen-Probe Incorporated
Inventor: Matthew J. Hayes , Byron J. Knight , Haitao Li , Robert F. Scalese
IPC: C12Q1/00 , G01N35/00 , G01N21/64 , C12Q1/68 , G01N21/76 , G01N35/02 , B01L7/00 , G01N35/10 , G01N35/04
CPC classification number: G01N21/6428 , B01L7/52 , C12Q1/6813 , C12Q1/6851 , G01N21/6454 , G01N21/76 , G01N35/00693 , G01N35/0092 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/026 , G01N35/028 , G01N35/04 , G01N35/1002 , G01N2021/6419 , G01N2021/6421 , G01N2021/6432 , G01N2021/6439 , G01N2021/6441 , G01N2035/00346 , G01N2035/00356 , G01N2035/00524 , G01N2035/0097 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0455 , G01N2035/0491 , G01N2035/103 , G01N2201/0415 , Y10S435/808 , Y10S435/809 , Y10T436/113332 , Y10T436/25 , C12Q2537/165
Abstract: To minimize cross talk in systems and methods for detecting two or more different optical signals emitted from each of a plurality of reaction receptacles, an excitation signal associated with each of the optical signals has a known excitation frequency, and any detected signal having a frequency that is inconsistent with the excitation frequency is discarded. The receptacles are moved relative to optical sensors configured to detect each unique optical signal from an associated receptacle, and to further minimize cross talk, the optical sensors are arranged so that only one reaction receptacle at a time is in a signal detecting position with respect to one of its associated optical sensors, and the optical sensors are grouped by the optical signal they are configured to detect so that a first optical signal is detected from each of the reaction receptacles before a second optical signal is detected from the reaction receptacles.
-
76.
公开(公告)号:US09162228B2
公开(公告)日:2015-10-20
申请号:US14210042
申请日:2014-03-13
Applicant: GEN-PROBE INCORPORATED
Inventor: Byron J. Knight
CPC classification number: B01L3/5085 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1002 , G01N35/1079 , G01N2035/00287 , Y10T436/11
Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
Abstract translation: 提供了用于执行基于自动化试剂的分析的系统,装置和方法。 还提供了用于将盖自动附接到反应容器的方法,以及从加盖的反应容器自动移除盖。
-
-
-
-
-