公开(公告)号：US20110132535A1

公开(公告)日：2011-06-09

申请号：US13026889

申请日：2011-02-14

Applicant: Kunihiko AKAI ,  Hiroshi KAWAZOE

Inventor： Kunihiko AKAI ,  Hiroshi KAWAZOE

IPC: B32B38/10 ,  B32B37/12 ,  B32B37/14

CPC classification number: B81B3/0067 ,  B01L3/502707 ,  B01L2200/025 ,  B01L2200/12 ,  B01L2300/0838 ,  B01L2300/0874 ,  B81B2201/051 ,  B81B2203/0338 ,  Y10T428/24612 ,  Y10T428/24752 ,  Y10T428/249921

Abstract: The present invention relates to a microfluid-system-supporting unit, comprising a fixing layer formed on a substrate, a protective layer or a fixing layer, wherein part of at least one hollow filament in any shape is placed and fixed in the fixing layer. Thus, it provides a microfluid-system-supporting unit lower in surface irregularity even when there are multiple hollow filaments different in external diameter or the hollow filaments crosses each other and resistant to positional deviation of the hollow filament in the crossing regions, and a production method thereof.

公开(公告)号：US20110104025A1

公开(公告)日：2011-05-05

申请号：US12988213

申请日：2009-04-23

Applicant: Yves Fouillet

Inventor： Yves Fouillet

IPC: B01L99/00 ,  B81C3/00

CPC classification number: B82Y30/00 ,  B01L3/502707 ,  B01L3/50273 ,  B01L2200/12 ,  B01L2300/0887 ,  B01L2400/0415 ,  B81B2201/051 ,  B81C1/00071 ,  B81C2201/0149

Abstract: A microfluidic device, including a microfluidic network, including: a) two parallel plates each including one or more electrodes, b) at least one channel, arranged between the two plates, made from a material obtained by solidification or hardening of a material of a first fluid, and c) a mechanism varying a physical parameter of the material constituting walls of the channel so as to cause the material to pass at least from the liquid state to the solid state.

Abstract translation: 包括微流体网络的微流体装置，包括：a）两个平行板，每个平行板包括一个或多个电极，b）布置在两个板之间的至少一个通道，由通过固化或硬化材料获得的材料制成 第一流体，以及c）改变通道的材料构成壁的物理参数以使材料至少从液态通过至固态的机构。

公开(公告)号：US20110027873A1

公开(公告)日：2011-02-03

申请号：US12936861

申请日：2009-04-10

Applicant: Sin Kil Cho ,  Seok Chung

Inventor： Sin Kil Cho ,  Seok Chung

IPC: C12M1/34 ,  G01N30/00

CPC classification number: B81C1/00103 ,  B01L3/502707 ,  B01L3/502723 ,  B01L3/50273 ,  B01L2200/16 ,  B01L2300/0636 ,  B01L2300/0663 ,  B01L2300/069 ,  B01L2300/0858 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/16 ,  B01L2400/0406 ,  B81B3/0094 ,  B81B2201/0214 ,  B81B2201/051 ,  B81B2201/058 ,  B81B2203/0338 ,  B81B2203/0392 ,  B81C2201/019

Abstract: Disclosed is a micro-nano fluidic biochip for assaying a biological sample comprising a first substrate, a second substrate and a third substrate which are sequentially stacked from bottom to top, wherein an upper channel assembly disposed on the second substrate is coupled with the lower channel assembly provided on the first substrate, to form a microfluidic channel, and the microfluidic channel has nano interstices formed at both sides thereof, the nano interstices having a height less than that of the center of the channel.

Abstract translation: 公开了一种用于分析生物样品的微纳米流体生物芯片，包括从底部到顶部顺序堆叠的第一基底，第二基底和第三基底，其中设置在第二基底上的上部通道组件与下部通道 组装设置在第一基底上，以形成微流体通道，并且微流体通道在其两侧形成有纳米间隙，该纳米间隙的高度小于通道中心的高度。

公开(公告)号：US07837821B2

公开(公告)日：2010-11-23

申请号：US12033958

申请日：2008-02-20

Applicant: Peng Zhou ,  Lincoln C. Young ,  Todd Roswech

Inventor： Peng Zhou ,  Lincoln C. Young ,  Todd Roswech

IPC: B32B38/04

CPC classification number: B29C66/54 ,  B01L3/502707 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2400/0481 ,  B01L2400/0655 ,  B01L2400/084 ,  B29C65/04 ,  B29C65/08 ,  B29C65/4895 ,  B29C65/72 ,  B29C66/1122 ,  B29C66/341 ,  B29C66/543 ,  B29C66/71 ,  B29L2031/756 ,  B81B2201/051 ,  B81C3/001 ,  B81C2201/019 ,  B81C2203/032 ,  F04B43/043 ,  F04B43/06 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0021 ,  F16K99/0034 ,  F16K99/0055 ,  F16K99/0057 ,  F16K2099/0074 ,  F16K2099/0078 ,  F16K2099/0084 ,  F16K2099/0094 ,  B29K2069/00 ,  B29K2033/12 ,  B29K2033/08 ,  B29K2025/06

Abstract: A method for making a polymeric microfluidic structure in which two or more components (layers) of the microfluidic structure are fixedly bonded or laminated with a weak solvent bonding agent, particularly acetonitrile or a mixture of acetonitrile and alcohol. In an aspect, acetonitrile can be used as a weak solvent bonding agent to enclose a microstructure fabricated in or on a non-elastomeric polymer such as polystyrene, polycarbonate, acrylic or other linear polymer to form a three-dimensional microfluidic network. The method involves the steps of wetting at least one of the opposing surfaces of the polymeric substrate components with the weak solvent bonding agent in a given, lower temperature range, adjacently contacting the opposing surfaces, and thermally activating the bonding agent at a higher temperature than the lower temperature range for a given period of time with RF or ultrasonic energy. The contacted polymeric substrates may also be aligned prior to thermal activation and compressed during thermal activation. A laminated, polymeric microfluidic structure is also disclosed.

Abstract translation: 一种制备聚合微流体结构的方法，其中微流体结构的两个或多个组分（层）用弱溶剂粘合剂，特别是乙腈或乙腈和醇的混合物固定粘合或层压。 在一个方面，乙腈可以用作弱溶剂粘合剂以包围在非弹性聚合物如聚苯乙烯，聚碳酸酯，丙烯酸或其它线性聚合物中或其上制造的微结构，以形成三维微流体网络。 该方法包括以下步骤：在给定的较低温度范围内用弱溶剂粘合剂润湿聚合物基材组分的至少一个相对表面，相邻接触相对表面，并在比 在一定时间内，RF或超声能量的较低温度范围。 接触的聚合物基材还可以在热活化之前对准，并在热活化期间被压缩。 还公开了层压聚合物微流体结构。

公开(公告)号：US20100178222A1

公开(公告)日：2010-07-15

申请号：US12664621

申请日：2008-06-13

Applicant: Kiyoshi Nokihara ,  Yasuo Oka

Inventor： Kiyoshi Nokihara ,  Yasuo Oka

IPC: B01J19/00

CPC classification number: B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00819 ,  B01J2219/00831 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01L3/502707 ,  B01L2200/0689 ,  B01L2300/0883 ,  B01L2300/12 ,  B81B2201/051 ,  B81B2201/058 ,  B81B2203/0307 ,  B81C3/001 ,  B81C2203/0109 ,  B81C2203/032

Abstract: Means for overcoming the problems which the conventional glass microchannel chips have are disclosed. That is, a microchannel chip in which microchannels can be formed at a low cost, and which has a high chemical resistance is disclosed. The microchannel chip is constituted by a substrate made of carbon, which has a channel in its surface; and a cover composed of a glass plate bonded to the substrate. The cover is bonded to the substrate by heating at least a part of the contact surface at which the substrate is in contact with the cover.

Abstract translation: 公开了克服传统玻璃微通道芯片所存在的问题的手段。 也就是说，公开了一种微通道芯片，其中可以以低成本形成微通道，并且具有高耐化学性。 微通道芯片由碳表面构成，其表面具有通道; 以及由与基板结合的玻璃板构成的盖。 通过加热基板与盖接触的接触表面的至少一部分，将盖结合到基板。

公开(公告)号：US07703313B2

公开(公告)日：2010-04-27

申请号：US11675043

申请日：2007-02-14

Applicant: Robert E. Higashi

Inventor： Robert E. Higashi

IPC: G01N25/00

CPC classification number: B81B3/0081 ,  B01L3/5027 ,  B01L3/502707 ,  B01L2200/14 ,  B01L2300/0627 ,  B01L2300/0816 ,  B01L2300/1827 ,  B81B2201/051 ,  B81B2201/058 ,  G01N30/6095 ,  G01N2030/025

Abstract: Embodiments of the invention relate to a fluid containment structure for a micro analyzer comprising one or more shelled thermal structures in contact with a thermally isolated component of the analyzer and wherein the shelled thermal structure comprises a conformal film and also comprises three walls of a channel and the thermally isolated component forms the fourth wall.

Abstract translation: 本发明的实施例涉及一种用于微分析器的流体容纳结构，其包括与分析仪的热隔离部件接触的一个或多个外壳热结构，并且其中所述带壳热结构包括保形膜，并且还包括三个通道壁和 热隔离部件形成第四壁。

公开(公告)号：US20100074815A1

公开(公告)日：2010-03-25

申请号：US12447392

申请日：2007-10-19

Applicant: Kanji Sekihara ,  Masayoshi Uehira

Inventor： Kanji Sekihara ,  Masayoshi Uehira

IPC: B29C33/42 ,  B28B1/00 ,  B81C1/00 ,  B81B1/00

CPC classification number: B29C33/42 ,  B29C33/3878 ,  B81B2201/051 ,  B81C99/0085

Abstract: Mold releasability of a molding die from a master is improved. The master is a mother body of the molding die. The master has a groove corresponding to a flow channel of a resin molded product, and the cross-section of the bottom surface portion of the groove is in the form of a curved surface.

Abstract translation: 提高了模具从母模的脱模性。 主人是模具的母体。 主机具有对应于树脂模制产品的流动通道的凹槽，并且凹槽的底表面部分的横截面为曲面形式。

公开(公告)号：US20100071418A1

公开(公告)日：2010-03-25

申请号：US12526900

申请日：2008-02-27

Applicant: Thierry Luc Alain Dannoux ,  Paulo Gaspar Jorge Marques ,  Robert Michael Morena ,  Cameron Wayne Tanner

Inventor： Thierry Luc Alain Dannoux ,  Paulo Gaspar Jorge Marques ,  Robert Michael Morena ,  Cameron Wayne Tanner

IPC: C03B17/00

CPC classification number: C03B11/084 ,  B81B2201/051 ,  B81C99/0085 ,  B81C2201/019 ,  B81C2201/036 ,  C03B2215/07

Abstract: Methods for molding glass and glass composites, including providing a first structure having a first surface, providing a second structure having a second surface, the second surface being patterned and porous, and disposing between the first and second surfaces an amount of a composition comprising a glass, then heating together the first and second structures and the first amount of the composition sufficiently to soften the first amount of the composition such that the first and second structures, under gravity or an otherwise applied force, move toward each other, such that the pattern of the second surface is formed into the first amount of the composition, then cooling the composition sufficiently to stabilize it, the second structure comprising porous carbon having an open porosity of at least 5% and wherein the amount of the composition is removable from the second surface, without damage to the amount of the composition or to the second surface, such that the second surface is in condition for re-use.

Abstract translation: 用于模制玻璃和玻璃复合材料的方法，包括提供具有第一表面的第一结构，提供具有第二表面的第二结构，第二表面被图案化和多孔化，并且在第一表面和第二表面之间设置一定量的组合物， 玻璃，然后将第一和第二结构和第一量的组合物充分加热以软化第一量的组合物，使得第一和第二结构在重力或以其他方式施加的力下朝向彼此移动，使得 将第二表面的图案形成为第一量的组合物，然后充分冷却组合物以使其稳定，第二结构包括具有至少5％的开放孔隙率的多孔碳，并且其中组合物的量可从 第二表面，而不损害组合物的量或第二表面，使得第二表面是 在重新使用的条件下。

公开(公告)号：US20090281250A1

公开(公告)日：2009-11-12

申请号：US12063284

申请日：2006-08-09

Applicant: Joseph M. DeSimone ,  Jason P. Rolland ,  Ginger M. Dennison Rothrock ,  Paul Resnick

Inventor： Joseph M. DeSimone ,  Jason P. Rolland ,  Ginger M. Dennison Rothrock ,  Paul Resnick

IPC: C08L67/00 ,  C08G18/71 ,  B05D3/00 ,  C08F2/48 ,  B44C1/22 ,  B29C33/40 ,  G03F7/00 ,  F15C3/00 ,  F15C5/00 ,  G05D7/00

CPC classification number: B29C59/005 ,  B01L3/502707 ,  B01L2300/0887 ,  B01L2300/12 ,  B29C33/3878 ,  B29C33/405 ,  B29C65/48 ,  B29C65/4835 ,  B29C65/4845 ,  B29C65/485 ,  B29C65/521 ,  B29C66/54 ,  B29C66/543 ,  B29C66/71 ,  B29C66/723 ,  B29C66/727 ,  B29C66/91431 ,  B29C66/919 ,  B29C66/949 ,  B29C66/9534 ,  B29K2883/00 ,  B29L2031/756 ,  B81B2201/051 ,  B81C99/0085 ,  C08G18/10 ,  C08G18/5015 ,  C08G18/8175 ,  C08G59/30 ,  C08G65/007 ,  C08L71/02 ,  C08L75/16 ,  Y10T137/0318 ,  Y10T137/2224 ,  C08G18/50 ,  B29C65/00 ,  B29K2027/18 ,  B29K2027/12

Abstract: Materials and Methods are provided for fabricating microfluidic devices. The materials include low surface energy fluoropolymer compositions having multiple cure functional groups. The materials can include multiple photocurable and/or thermal-curable functional groups such that laminate devices can be fabricated. The materials also substantially do not swell in the presence of hydrocarbon solvents.

Abstract translation: 提供材料和方法用于制造微流体装置。 这些材料包括具有多个固化官能团的低表面能含氟聚合物组合物。 这些材料可以包括多个可光固化和/或热固化的官能团，使得可以制造层压装置。 所述材料在烃溶剂存在下也基本上不溶胀。

公开(公告)号：US20090274586A1

公开(公告)日：2009-11-05

申请号：US12502394

申请日：2009-07-14

Applicant: Hiroshi KAWAZOE ,  Akishi NAKASO ,  Shigeharu ARIKE

Inventor： Hiroshi KAWAZOE ,  Akishi NAKASO ,  Shigeharu ARIKE

IPC: B01L3/00

CPC classification number: B01L3/502707 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00788 ,  B01J2219/00822 ,  B01J2219/00833 ,  B01J2219/0086 ,  B01J2219/00869 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2400/0481 ,  B01L2400/0655 ,  B81B2201/051 ,  B81C1/00119 ,  B81C2201/019 ,  B81C2203/032 ,  Y10T156/10

Abstract: A support unit for a microfluidic system includes a first support; a first adhesive layer provided on a surface of the first support; and a hollow filament laid on a surface of the first adhesive layer to have an arbitrary shape and functioning as a flow channel layer of the microfluidic system.