公开(公告)号：US20160146733A1

公开(公告)日：2016-05-26

申请号：US14784569

申请日：2013-09-10

Applicant: PLEXENCE, INC.

Inventor： Gibum Kim

IPC: G01N21/552

CPC classification number: G01N21/554 ,  B81C1/0038 ,  G01N2201/068

Abstract: The present invention relates to a method for manufacturing a nanoparticle array, a surface plasmon resonance-based sensor, and a method for analyzing using the same. According to one embodiment of the present invention, after a mixed solution of an ionized binder and conductive nanoparticles is prepared, a substrate is dipped into the mixed solution. Thereafter, by applying an electric field to the mixed solution into which the substrate is dipped so as to induce coating of the conductive nanoparticles on the substrate, it is possible to manufacture, by a wet method, a nanoparticle array in which the conductive nanoparticles are quickly coated on the substrate with high density.

Abstract translation: 本发明涉及一种制造纳米颗粒阵列的方法，一种基于表面等离子体共振的传感器和一种使用该传感器进行分析的方法。 根据本发明的一个实施方案，在制备离子化粘合剂和导电纳米颗粒的混合溶液之后，将基材浸入混合溶液中。 然后，通过对浸渍有基板的混合溶液施加电场，以引起基板上的导电性纳米粒子的覆盖，可以通过湿法制造导电性纳米粒子为纳米粒子的纳米粒子阵列 以高密度迅速涂在基材上。

公开(公告)号：US20160145280A1

公开(公告)日：2016-05-26

申请号：US14784939

申请日：2014-04-21

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Sydney Brenner ,  Yin Nah Teo ,  Pee Mei Tan

IPC: C07F9/655 ,  C07H21/04 ,  G01N21/64 ,  C07F7/18

CPC classification number: C12Q1/6818 ,  C07D207/46 ,  C07D493/10 ,  C07F7/12 ,  C07F7/1804 ,  C07F9/1651 ,  C07F9/2408 ,  C07F9/65522 ,  C07F9/6561 ,  C07F9/65616 ,  C07H21/04 ,  C09B11/08 ,  C09B23/06 ,  C09B29/0003 ,  G01N21/6428 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2201/068

Abstract: The invention relates to cleavable chemistry in general, and in particular, to tunable fluorescence using cleavable linkers present in fluorochrome-quencher conjugates.

Abstract translation: 本发明一般涉及可切割化学，特别涉及使用荧光染料 - 猝灭剂缀合物中存在的可切割接头的可调谐荧光。

公开(公告)号：US09347891B2

公开(公告)日：2016-05-24

申请号：US14381315

申请日：2013-03-01

Applicant: KLA-Tencor Corporation

Inventor： Grace H. Chen ,  Rudolf Brunner ,  Lisheng Gao ,  Robert M. Danen ,  Lu Chen

IPC: G01N21/00 ,  G01N21/88 ,  G01N21/956

CPC classification number: G01N21/8806 ,  G01N21/8851 ,  G01N21/9501 ,  G01N21/956 ,  G01N21/95623 ,  G01N2021/8822 ,  G01N2021/95676 ,  G01N2201/061 ,  G01N2201/0638 ,  G01N2201/068 ,  G01N2201/12

Abstract: In an optical inspection tool, an illumination aperture is opened at each of a plurality of aperture positions of an illumination pupil area one at a time across the illumination pupil area. For each aperture opening position, an incident beam is directed towards the illumination pupil area so as to selectively pass a corresponding ray bundle of the illumination beam at a corresponding set of one or more incident angles towards the sample and an output beam, which is emitted from the sample in response to the corresponding ray bundle of the incident beam impinging on the sample at the corresponding set of one or more incident angles, is detected. A defect detection characteristic for each aperture position is determined based on the output beam detected for each aperture position. An optimum aperture configuration is determined based on the determined defect detection characteristic for each aperture position.

Abstract translation: 在光学检查工具中，照明光圈在照明光瞳区域的多个孔径位置中的每一个处打开，一次一个地穿过照明瞳孔区域。 对于每个光圈打开位置，入射光束被引向照明光瞳区域，以便选择性地将照射光束的相应光束束以对应于一个或多个入射角的一组对应于样品的输出光束和输出光束 检测来自样品的响应于在相应的一个或多个入射角度的入射光束入射到样品上的相应射线束。 基于针对每个孔径位置检测的输出光束来确定每个光圈位置的缺陷检测特性。 基于针对每个孔位置确定的缺陷检测特性来确定最佳孔径配置。

公开(公告)号：US09335268B2

公开(公告)日：2016-05-10

申请号：US14607274

申请日：2015-01-28

Applicant: LRE Medical GmbH

Inventor： Rafael Egger ,  Jörg Zeiner

IPC: G01N21/64 ,  G01N21/27

CPC classification number: G01N21/645 ,  G01N21/278 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/068

Abstract: A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (λex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (λex1), have a first excitation efficiency and, given an immission of light of a second wavelength (λex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.

公开(公告)号：US20160123878A1

公开(公告)日：2016-05-05

申请号：US14890372

申请日：2014-05-12

Applicant: KING'S COLLEGE LONDON

Inventor： Anatoly ZAYATS ,  Wayne DICKSON ,  Mazhar Ejaz NASIR

IPC: G01N21/552 ,  G01N33/00

CPC classification number: G01N21/554 ,  G01N21/77 ,  G01N33/005 ,  G01N2021/7773 ,  G01N2021/7783 ,  G01N2201/06113 ,  G01N2201/068

Abstract: A plasmonic hydrogen detector and method of constructing a plasmonic hydrogen detector. The plasmonic hydrogen detector comprises: a structure comprising a support and a plurality of nanostructure elements. The plurality of nanostructure elements comprise a plasmonic material and a hydrogen sensitive material. The plurality of nanostructure elements are configured on the support to allow the structure to act as a plasmonic metamaterial. The hydrogen sensitive material is configured to cause a change in permittivity of the plasmonic metamaterial in the presence of hydrogen. Aspects and embodiments described recognise that use of a plasmonic metamaterial as a hydrogen detector can result in a highly sensitive detector. That sensitivity stems from the sensitivity of strong plasmonic coupling between individual nanostructure elements in the metamaterial to external perturbations, for example, as a result of a physical or chemical environmental change.

Abstract translation: 等离子体氢探测器及构造等离子体氢探测器的方法。 等离子体氢气检测器包括：包括支撑体和多个纳米结构元件的结构。 多个纳米结构元件包括等离子体激元材料和氢敏材料。 多个纳米结构元件配置在支撑体上以允许结构充当等离子体激元超材料。 氢敏材料被配置为在氢的存在下引起等离子体激元超材料的介电常数的变化。 所描述的方面和实施例认识到，使用等离子体激元超材料作为氢气检测器可导致高度敏感的检测器。 这种敏感性源于超材料中的单个纳米结构元件与外部扰动之间的强等离子体耦合的敏感性，例如由于物理或化学环境变化的结果。

公开(公告)号：US09291559B2

公开(公告)日：2016-03-22

申请号：US13790559

申请日：2013-03-08

Applicant: United States Postal Service

Inventor： Khalid Hussain ,  Marie Therese Dominguez ,  David E. Failor ,  William G. Ackerman

IPC: G06K7/10 ,  G01N21/64 ,  B41K3/00 ,  G07D7/12 ,  G06K19/14 ,  B42D25/29 ,  B42D25/382 ,  B42D25/387

CPC classification number: B42D25/47 ,  B41K3/00 ,  B41M3/008 ,  B41M3/144 ,  B42D25/29 ,  B42D25/36 ,  B42D25/382 ,  B42D25/387 ,  G01N21/64 ,  G01N21/643 ,  G01N2021/6421 ,  G01N2021/6423 ,  G01N2201/061 ,  G01N2201/068 ,  G06K19/14 ,  G07D7/1205

Abstract: A method of illuminating an item is disclosed. The method includes applying adhesive to the item, interspersing a taggant in the adhesive, illuminating the item with an excitation signal, sensing luminescence emitted by the taggant in response to illumination by the excitation signal, and determining the authenticity of the item based on the sensed emitted luminescence. The item can include any item benefited by authentication, and can include a postage stamp. A method of customizing an item is disclosed. This can include the steps of preparing a substrate, applying a security feature to the substrate, printing non-customized information on the substrate, receiving image information, and printing the image information on the substrate.

Abstract translation: 公开了一种照亮物品的方法。 该方法包括将粘合剂施加到物品上，将标签剂穿在粘合剂中，用激发信号照亮物品，响应于激发信号的照明感测由标签牌发出的发光，以及基于感测到的物品确定物品的真实性 发出发光。 该项目可以包括通过认证受益的任何项目，并且可以包括邮票。 公开了一种定制物品的方法。 这可以包括准备衬底，将安全特征应用于衬底，在衬底上打印非定制信息，接收图像信息以及在衬底上打印图像信息的步骤。

公开(公告)号：US09291553B2

公开(公告)日：2016-03-22

申请号：US14400323

申请日：2013-05-07

Applicant: PANARIDUS, LLC

Inventor： Michael Fraley

IPC: G01J5/02 ,  G01N21/359 ,  G01N21/84 ,  G01N33/00

CPC classification number: G01N21/359 ,  G01J3/0262 ,  G01J3/42 ,  G01N21/255 ,  G01N21/3563 ,  G01N21/84 ,  G01N33/0098 ,  G01N2021/8466 ,  G01N2201/0216 ,  G01N2201/061 ,  G01N2201/068 ,  G01N2201/129

Abstract: A system and method for in-field near infrared spectroscopy (NIRS) analysis of rubber and resin concentrations a guayule plant is provided. The system includes a wagon or other vehicle with the NIRS device mounted on the wagon. A computer or processor electrically coupled to the NIRS device is also housed within an area or extension of the wagon. During measurement of a guayule plant in the field, a guayule plant covering is placed over the guayule plant and a light shield coupled to the NIRS device is inserted into an opening on the guayule plant covering. The NIRS device is configured to perform a reading of the guayule plant within the plant covering and communicate results of the reading to the computer. A calibration equation is then preferably applied to the guayule plant readings to produce the rubber and resin concentrations of the guayule plant.

公开(公告)号：US20160077006A1

公开(公告)日：2016-03-17

申请号：US14948972

申请日：2015-11-23

Applicant: Sony Corporation

Inventor： Yuji Segawa ,  Tasuku Yotoriyama ,  Shinichi Kai

IPC: G01N21/64 ,  B01L3/00 ,  B01L7/00

CPC classification number: G01N21/6454 ,  B01L3/50851 ,  B01L7/52 ,  B01L2300/0627 ,  B01L2300/0654 ,  B01L2300/1822 ,  B01L2300/1827 ,  G01N21/6428 ,  G01N2201/068

Abstract: Disclosed herein is an optical detector at least including: a first substrate in which a plurality of wells are formed; a second substrate in which a heating section is provided to heat the wells; a third substrate in which a plurality of photoirradiation sections are provided in alignment with the wells; and a fourth substrate in which a plurality of photodetection sections are provided in alignment with the wells.

公开(公告)号：US09285316B2

公开(公告)日：2016-03-15

申请号：US14340298

申请日：2014-07-24

Applicant: Applied Biosystems, LLC

Inventor： Richard Reel ,  Eric Nordman

IPC: G01N21/64 ,  G01N27/447 ,  F21V5/00

CPC classification number: G01N21/64 ,  F21V5/00 ,  G01N21/645 ,  G01N27/44721 ,  G01N2021/6463 ,  G01N2201/068 ,  Y10T436/143333

Abstract: System and method for fluorescent light excitation and detection from samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light. The system for analyzing samples comprising: a light source that provides a non-coherent excitation light; at least one housing, wherein the housing transports samples and propagates the non-coherent excitation light by total internal reflection; a coupling optical element configured to introduce the non-coherent excitation light into the at least one housing through a wall of the at least one housing; and at least one NA enhancing optical element to collect an emitted fluorescence, wherein the NA enhancing optical element is constructed of a first material and the housing is constructed of a second material, wherein the first material has a greater index of refraction than the second material.

Abstract translation: 用于荧光灯激发和检测样品的系统和方法，以提高数值孔径和/或减少荧光灯的串扰。 用于分析样品的系统包括：提供非相干激发光的光源; 至少一个壳体，其中壳体传输采样并通过全内反射传播非相干激发光; 耦合光学元件，被配置为通过所述至少一个壳体的壁将所述非相干激发光引入所述至少一个壳体; 以及至少一个NA增强光学元件以收集发射的荧光，其中所述NA增强光学元件由第一材料构成，并且所述壳体由第二材料构成，其中所述第一材料具有比所述第二材料更大的折射率 。

公开(公告)号：US20160061744A1

公开(公告)日：2016-03-03

申请号：US14472939

申请日：2014-08-29

Applicant: Jutta Krebber ,  Kattkus Klaus

Inventor： Jutta Krebber ,  Kattkus Klaus

IPC: G01N21/88 ,  G01B11/30

CPC classification number: G01B11/306 ,  G01N21/8803 ,  G01N2201/0616 ,  G01N2201/068

Abstract: The present invention comprises a surface to maximize the viewing of an impression in a vehicle body. This may comprise a fabric which has at least one dark colored stripe parallel to at least one light colored stripe; a compressible frame across which the said fabric is affixed, where when the frame is uncompressed the fabric is stretched taut across the frame and where the frame is compressed the fabric is slack across the frame; and a handle on the frame where a user can hold the frame and not interfere with the fabric affixed to said frame. When a user is holding the handle of the frame at an angle between 0° and 180°, the user can reflect radiant energy through said fabric onto the vehicle body and create a whorl reflection pattern on the impression to maximize viewing of said impression by the user.

Abstract translation: 本发明包括使车身中的印象观看最大化的表面。 这可以包括具有平行于至少一个浅色条纹的至少一​​个深色条纹的织物; 一个可压缩的框架，所述织物固定在该可压缩框架上，其中当框架未被压缩时，织物被拉伸跨过框架并且框架被压缩，织物在框架之间松弛; 以及框架上的用户可以握住框架并且不干扰固定到所述框架上的织物的手柄。 当用户以0°和180°之间的角度握住框架的手柄时，用户可以将辐射能量通过所述织物反射到车身上，并在印模上产生螺旋反射图案，以最大程度地观察所述印象 用户。