MACHINE FOR DETECTING TINY PARTICLES
    81.
    发明申请

    公开(公告)号:US20170160207A1

    公开(公告)日:2017-06-08

    申请号:US14960349

    申请日:2015-12-05

    Inventor: Ming-Sheng Chen

    Abstract: A machine for inspecting a face of a transparent plate includes a frame, a carrier module, an optical module and at least two illumination modules. The frame includes an X-axis. The carrier module is adapted for carrying a transparent plate in need of inspection on the frame along the X-axis. The optical module is located on the frame and movable relative to the carrier module and includes at least one detector adapted for rectilinear scanning along a Y-axis perpendicularly intersecting the X-axis of the carrier module at a crossing point. The illumination modules are located on two opposite sides of the X-axis of the frame. Each of the illumination modules includes a laser emitter. The laser emitters are located at a same distance from the crossing point and adapted for emitting rays on the transparent plate at a same angle of 0.5° to 6°.

    LASER SCANNING MICROSCOPE APPARATUS
    88.
    发明申请
    LASER SCANNING MICROSCOPE APPARATUS 审中-公开
    激光扫描显微镜设备

    公开(公告)号:US20160306152A1

    公开(公告)日:2016-10-20

    申请号:US15132053

    申请日:2016-04-18

    Abstract: A laser scanning microscope apparatus includes an irradiation unit including an objective lens, a photodetector unit, an XY-scanning unit, and a Z-scanning unit. The irradiation unit focuses a laser beam with the objective lens to a specimen. The photodetector unit detects light generated from a position irradiated with the laser beam focused. The XY-scanning unit scans the laser beam in an X-direction perpendicular to an optical axis of the objective lens and in a Y-direction perpendicular to the optical axis and the X-direction. The Z-scanning unit scans the laser beam in a Z-direction parallel to the optical axis. When acquiring XY-two-dimensional image data by detecting the light while scanning the irradiated position in the X-direction and the Y-direction, the apparatus detects the light while scanning the irradiated position also in the Z-direction.

    Abstract translation: 激光扫描显微镜装置包括具有物镜,光电检测器单元,XY扫描单元和Z扫描单元的照射单元。 照射单元将具有物镜的激光束聚焦到样本。 光检测器单元检测从被聚焦的激光束照射的位置产生的光。 XY扫描单元在垂直于物镜的光轴的X方向和垂直于光轴和X方向的Y方向扫描激光束。 Z扫描单元沿平行于光轴的Z方向扫描激光束。 当通过在X方向和Y方向扫描照射位置时检测光来获取XY二维图像数据时,该装置也在沿Z方向扫描照射位置的同时检测光。

    Optical analysis device, optical analysis method and computer program for optical analysis using single light-emitting particle detection
    89.
    发明授权
    Optical analysis device, optical analysis method and computer program for optical analysis using single light-emitting particle detection 有权
    光学分析装置,光学分析方法和使用单个发光粒子检测的光学分析的计算机程序

    公开(公告)号:US09423349B2

    公开(公告)日:2016-08-23

    申请号:US14178442

    申请日:2014-02-12

    Abstract: In the scanning molecule counting method detecting light of a light-emitting particle in a sample solution using a confocal or multiphoton microscope, there is provided an optical analysis technique enabling the scanning in a sample solution with moving a light detection region in a broader area or along a longer route while making the possibility of detecting the same light-emitting particle as different particles as low as possible and remaining the size or shape of the light detection region unchanged as far as possible. In the inventive optical analysis technique, there are performed detecting light from the light detection region and generating time series light intensity data during moving the light detection region along the second route whose position is moved along the first route, and thereby, the signal indicating light from each light-emitting particle in a predetermined route is individually detected using the time series light intensity data.

    Abstract translation: 在使用共聚焦或多光子显微镜检测样品溶液中的发光粒子的光的扫描分子计数方法中,提供了一种光学分析技术,其能够在较宽区域中移动光检测区域的样品溶液中进行扫描,或 沿着较长的路线,同时尽可能地检测与不同粒子相同的发光粒子的可能性,并尽可能地保持光检测区域的尺寸或形状不变。 在本发明的光学分析技术中,在沿着沿第一路线移动位置的第二路径移动光检测区域的同时,进行来自光检测区域的检测光并产生时间序列光强度数据,由此,指示光 使用时间序列光强度数据分别检测来自预定路线中的每个发光粒子。

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