公开(公告)号：US09764030B2

公开(公告)日：2017-09-19

申请号：US14404469

申请日：2013-06-11

Applicant: NANO3D BIOSCIENCES INC.

Inventor： Glauco R. Souza

IPC: C12N5/00 ,  A61K41/00 ,  A61N2/00 ,  A61L27/18 ,  A61L27/38 ,  A61L27/50 ,  G01N33/543 ,  G01N33/58 ,  B03C1/01 ,  B03C1/034 ,  B03C1/30

CPC classification number: A61K41/0052 ,  A61L27/18 ,  A61L27/38 ,  A61L27/50 ,  A61L2400/12 ,  A61L2430/20 ,  A61L2430/30 ,  A61N2/00 ,  B03C1/01 ,  B03C1/034 ,  B03C1/30 ,  B03C2201/26 ,  C12N5/0062 ,  C12N5/0068 ,  C12N2529/00 ,  G01N33/54346 ,  G01N33/587

Abstract: Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.

公开(公告)号：US09731391B2

公开(公告)日：2017-08-15

申请号：US14394740

申请日：2013-04-22

Applicant: NANO3D BIOSCIENCES INC.

Inventor： Glauco R. Souza ,  Jianbo Chen

IPC: B23Q1/03 ,  G03B15/00 ,  G02B27/02 ,  G03B17/56 ,  H04N1/00 ,  G01N21/25 ,  G01N21/64

CPC classification number: B23Q1/03 ,  G01N21/253 ,  G01N21/6452 ,  G02B27/028 ,  G03B15/00 ,  G03B17/56 ,  H04N1/00541

Abstract: Camera phone accessories for using the camera phone to collect scientific data.

公开(公告)号：US09688955B2

公开(公告)日：2017-06-27

申请号：US14536388

申请日：2014-11-07

Applicant: NANO3D BIOSCIENCES INC.

Inventor： Glauco R. Souza

IPC: C12N13/00 ,  C12N5/00 ,  C12N5/07 ,  C12Q1/02 ,  C12Q1/24 ,  B03C1/015 ,  B03C1/30 ,  B82Y25/00 ,  G01N33/543 ,  G01N33/544 ,  G01R33/12 ,  H01F1/00 ,  H01F1/08 ,  H01F1/113 ,  H01F1/44 ,  C40B30/04 ,  G01N33/566 ,  G01N33/68

CPC classification number: C12N5/0062 ,  B03C1/015 ,  B03C1/30 ,  B03C2201/26 ,  B82Y25/00 ,  C12N5/00 ,  C12N2513/00 ,  C12N2529/00 ,  C12N2531/00 ,  C12N2533/10 ,  C12N2533/32 ,  G01N33/54326 ,  G01N33/544 ,  G01R33/1269 ,  H01F1/0045 ,  H01F1/0063 ,  H01F1/083 ,  H01F1/113 ,  H01F1/445 ,  Y10S977/773 ,  Y10S977/89 ,  Y10S977/904 ,  Y10S977/923

Abstract: A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.

公开(公告)号：US20150275165A9

公开(公告)日：2015-10-01

申请号：US13762103

申请日：2013-02-07

Applicant: Nano3D Biosciences, Inc

Inventor： Glauco SOUZA

IPC: C12M1/00 ,  B01L3/02

CPC classification number: C12M47/02 ,  B01L3/021 ,  B01L3/0217 ,  B01L3/0289 ,  B01L2200/0657 ,  B01L2300/0838 ,  B01L2400/043 ,  C12M23/10 ,  C12M23/12 ,  C12M23/38 ,  C12M33/04 ,  C12M35/06

Abstract: Devices for magnetic 3d culture are described including magnetic lids/bases for single Petri plates, adjustable height cap for same, as well similar devices for multi-magnet culture plates. A pen-like device for sterilely lifting and moving cells is also described, and this magnetic pipettor can also exist in multi-well magnetic pipettor formats.

Abstract translation: 描述了用于磁性3d培养的装置，其包括用于单个培养板的磁性盖/底座，用于相同的可调高度盖，以及用于多磁体培养板的类似装置。 还描述了用于无菌提升和移动细胞的笔状装置，并且该磁性移液器也可以以多孔磁吸管器形式存在。

公开(公告)号：US20140220672A1

公开(公告)日：2014-08-07

申请号：US13762103

申请日：2013-02-07

Applicant: Nano3D Biosciences, Inc

Inventor： Glauco SOUZA

IPC: C12M1/00 ,  B01L3/02

CPC classification number: C12M47/02 ,  B01L3/021 ,  B01L3/0217 ,  B01L3/0289 ,  B01L2200/0657 ,  B01L2300/0838 ,  B01L2400/043 ,  C12M23/10 ,  C12M23/12 ,  C12M23/38 ,  C12M33/04 ,  C12M35/06

Abstract: Devices for magnetic 3d culture are described including magnetic lids/bases for single Petri plates, adjustable height cap for same, as well similar devices for multi-magnet culture plates. A pen-like device for sterilely lifting and moving cells is also described, and this magnetic pipettor can also exist in multi-well magnetic pipettor formats.

Abstract translation: 描述了用于磁性3d培养的装置，其包括用于单个培养板的磁性盖/底座，用于相同的可调高度盖，以及用于多磁体培养板的类似装置。 还描述了用于无菌提升和移动细胞的笔状装置，并且该磁性移液器也可以以多孔磁吸管器形式存在。

公开(公告)号：US20130280754A1

公开(公告)日：2013-10-24

申请号：US13995610

申请日：2012-01-13

Applicant: Glauco R. Souza

Inventor： Glauco R. Souza

IPC: G01N33/50

CPC classification number: G01N33/5088 ,  G01N33/5082

Abstract: Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell cell interactions.

Abstract translation: 细胞生长在3D培养中，通过显微照相获得的拓扑特征与细胞活力和细胞相互作用相关。