公开(公告)号：US11530266B2

公开(公告)日：2022-12-20

申请号：US16626162

申请日：2019-06-14

Applicant: JAPANESE FOUNDATION FOR CANCER RESEARCH ,  API CO., LTD.

Inventor： Nobuhiko Gyobu ,  Naoya Fujita ,  Mamoru Kakino ,  Ai Kawashima ,  Shinya Fujihara ,  Naoki Goda

IPC: C07K16/28 ,  C07K16/46 ,  A61K39/00

Abstract: The object of the present invention is to provide a humanized or mouse-human chimeric anti-podoplanin antibody or an antibody fragment containing the antigen-binding region thereof, and the object is achieved by providing an isolated humanized or mouse-human chimeric anti-podoplanin antibody which comprises a predetermined amino acid sequence, or an antibody fragment containing the antigen-binding region thereof.

公开(公告)号：US20210403555A1

公开(公告)日：2021-12-30

申请号：US16626162

申请日：2019-06-14

Applicant: JAPANESE FOUNDATION FOR CANCER RESEARCH ,  API CO., LTD.

Inventor： Nobuhiko GYOBU ,  Naoya FUJITA ,  Mamoru KAKINO ,  Ai KAWASHIMA ,  Shinya FUJIHARA ,  Naoki GODA

IPC: C07K16/28 ,  C07K16/46

Abstract: The object of the present invention is to provide a humanized or mouse-human chimeric anti-podoplanin antibody or an antibody fragment containing the antigen-binding region thereof, and the object is achieved by providing an isolated humanized or mouse-human chimeric anti-podoplanin antibody which comprises a predetermined amino acid sequence, or an antibody fragment containing the antigen-binding region thereof.