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公开(公告)号：US20220241787A1
公开(公告)日：2022-08-04
申请号：US17626445
申请日：2020-07-13
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Piotr GARSTECKI , Kamil Robert GEWARTOWSKI , Piotr KNAP , Maciej LIRSKI
IPC: B01L3/00
Abstract: A microfluidic chip for partitioning a liquid composition into multiple aliquots has a processing compartment including an inlet and an outlet, wherein the outlet of the processing compartment is connected either to an inlet of the compression compartment or wherein in case a compression channel is present, the outlet of the processing compartment is connected to the compression channel, which is connected to the inlet of the compression compartment, preferably wherein each of the compression compartments exhibits the same volume.
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2.发明申请DEVICE FOR SIMULTANEOUS AND UNIFORM THERMAL CYCLING OF SAMPLES AND USES THEREOF 有权用于同时和均匀的样品的热循环装置及其用途公开(公告)号：US20160167054A1
公开(公告)日：2016-06-16
申请号：US15048731
申请日：2016-02-19
Applicant: Curiosity Diagnostics sp. z o.o.
Inventor： Krzysztof MELLEM , Daniel Krzystof GORZKOWSKI , Seweryn BAJER-BORSTYN , Pawel ZAWADZKI , Piotr GARSTECKI , Kamil Robert GEWARTOWSKI
CPC classification number: B01L7/52 , B01L2300/0654 , B01L2300/168 , B01L2300/1811 , B01L2300/1827 , B01L2300/1872 , C12Q1/686
Abstract: The invention relates to thermal cycling device comprising: a sample location; a first heating means, wherein advantageously said first heating means is a contact heating means; a second heating means, wherein said second heating means is configured to bring said sample to a second temperature by directing electromagnetic radiation to the first light pipe section end and the light pipe section is configured to direct said electromagnetic radiation through its second end to the sample location, its uses and methods based thereon.
Abstract translation: 本发明涉及热循环装置，包括：样品位置; 第一加热装置，其中有利地，所述第一加热装置是接触加热装置; 第二加热装置，其中所述第二加热装置被配置为通过将电磁辐射引导到第一光管部分端部将所述样品带到第二温度，并且所述光管部分被配置为将所述电磁辐射通过其第二端到所述样品 位置，其用途和方法。
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3.发明公开公开(公告)号：US20240316551A1
公开(公告)日：2024-09-26
申请号：US18271648
申请日：2022-01-11
Applicant: Curiosity Diagnostics Sp. z o.o.
Inventor： Kamil Robert Gewartowski , Piotr Garstecki , Maciej Lirski , Krzysztof Wisniewski , Pawel Debski
CPC classification number: B01L3/502761 , B01L3/502738 , C12N15/1013 , B01L2200/027 , B01L2200/0668 , B01L2200/16 , B01L2400/06
Abstract: Disclosed is a microfluidic circuit, microfluidic chip, kit and method for isolating and purifying an analyte, preferably a nucleic acid.
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公开(公告)号：US20220396828A1
公开(公告)日：2022-12-15
申请号：US17776160
申请日：2020-11-16
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Kamil GEWARTOWSKI , Bartosz BARANOWSKI , Anna KOZLOWICZ
IPC: C12Q1/689 , C12Q1/6813
Abstract: Disclosed is a primer pair and an oligonucleotide probe for hybridizing to at least a portion of a chloramphenicol acetyltransferase gene coded in a transposon of family CTn-027 of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group, an oligonucleotide set for use in a nucleic acid amplification process or a nucleic acid detection process for determining the presence of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group in a sample, a kit for detecting the presence of a hyper-virulent strain of Clostridioides difficile of the B1/NAP1/027 group in a sample, and a method of determining the presence or absence of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group in a sample.
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公开(公告)号：US10209246B2
公开(公告)日：2019-02-19
申请号：US14411303
申请日：2013-03-15
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Pawel Rafal Debski , Adam Warchulski , Piotr Garstecki
IPC: G01N33/48 , G01N33/50 , G01N33/53 , C12Q1/6851
Abstract: The present invention relates to a method for determining an estimate of a concentration of analyte particles E(C) as well as an apparatus for use in the inventive method, uses of the inventive method or the inventive apparatus, a sample holder and a kit for use in the inventive method.
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Patent Agency Ranking
公开(公告)号：US09737892B2
公开(公告)日：2017-08-22
申请号：US15048731
申请日：2016-02-19
Applicant: Curiosity Diagnostics sp. z o.o.
Inventor： Krzysztof Mellem , Daniel Krzystof Gorzkowski , Seweryn Bajer-Borstyn , Pawel Zawadzki , Piotr Garstecki , Kamil Robert Gewartowski
CPC classification number: B01L7/52 , B01L2300/0654 , B01L2300/168 , B01L2300/1811 , B01L2300/1827 , B01L2300/1872 , C12Q1/686
Abstract: The invention relates to thermal cycling device comprising: a sample location; a first heating means, wherein advantageously said first heating means is a contact heating means; a second heating means, wherein said second heating means is configured to bring said sample to a second temperature by directing electromagnetic radiation to the first light pipe section end and the light pipe section is configured to direct said electromagnetic radiation through its second end to the sample location, its uses and methods based thereon.
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公开(公告)号：US12017220B2
公开(公告)日：2024-06-25
申请号：US17626611
申请日：2020-07-13
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Pawel Solczynski , Piotr Garstecki
CPC classification number: B01L3/502738 , B81B1/006 , B81C1/00119 , B01L2200/027 , B01L2200/12 , B01L2300/0609 , B01L2300/123 , B01L2400/0638 , B81B2201/054 , B81B2203/0338 , B81B2203/0353
Abstract: The present invention relates to a microfluidic chip and valve, production process and uses thereof according to the independent claims.
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公开(公告)号：US20220241785A1
公开(公告)日：2022-08-04
申请号：US17626611
申请日：2020-07-13
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Pawel SOLCZYNSKI , Piotr GARSTECKI
Abstract: The present invention relates to a microfluidic chip and valve, production process and uses thereof according to the independent claims.
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公开(公告)号：US20170322136A1
公开(公告)日：2017-11-09
申请号：US15658073
申请日：2017-07-24
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Piotr Garstecki , Pawel Rafal Debski , Michal Oszmaniec , Tomasz Kaminski , Adam Warchulski
CPC classification number: G01N15/06 , C12Q1/6851 , G01N2015/0038 , C12Q2537/165 , C12Q2563/159
Abstract: The present invention relates to a method for determining an estimate of a concentration of particles E(C), wherein a sample of predetermined volume is divided into a number (N) of compartments, the (N) compartments comprise or consist of different sample volumes (vi) and/or different dilution factors (di) of the sample, at least part of the particles that are present in any of the (N) compartments provide a measurable signal and the estimated concentration of particles E(C) is a function of measured signals, as well as an apparatus for use in the inventive method, uses of the inventive method, a sample holder and a kit for use in the inventive method.
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公开(公告)号：US20150204858A1
公开(公告)日：2015-07-23
申请号：US14411303
申请日：2013-03-15
Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.
Inventor： Pawel Rafal Debski , Adam Warchulski , Piotr Garstecki
CPC classification number: G01N33/5306 , C12Q1/6851 , C12Q2527/146 , C12Q2537/165
Abstract: The present invention relates to a method for determining an estimate of a concentration of analyte particles E(C) as well as an apparatus for use in the inventive method, uses of the inventive method or the inventive apparatus, a sample holder and a kit for use in the inventive method.
Abstract translation: 本发明涉及一种用于确定分析物颗粒E（C）的浓度估计的方法以及用于本发明方法的装置，本发明方法或本发明装置的用途，样品架和用于 用于本发明的方法。
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