公开(公告)号：US20220396828A1

公开(公告)日：2022-12-15

申请号：US17776160

申请日：2020-11-16

Applicant: CURIOSITY DIAGNOSTICS SP. Z O.O.

Inventor： Kamil GEWARTOWSKI ,  Bartosz BARANOWSKI ,  Anna KOZLOWICZ

IPC: C12Q1/689 ,  C12Q1/6813

Abstract: Disclosed is a primer pair and an oligonucleotide probe for hybridizing to at least a portion of a chloramphenicol acetyltransferase gene coded in a transposon of family CTn-027 of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group, an oligonucleotide set for use in a nucleic acid amplification process or a nucleic acid detection process for determining the presence of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group in a sample, a kit for detecting the presence of a hyper-virulent strain of Clostridioides difficile of the B1/NAP1/027 group in a sample, and a method of determining the presence or absence of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group in a sample.