公开(公告)号：US5194912A

公开(公告)日：1993-03-16

申请号：US543729

申请日：1990-08-06

Applicant: David N. Batchelder ,  Chunwei Cheng ,  Brian J. E. Smith

Inventor： David N. Batchelder ,  Chunwei Cheng ,  Brian J. E. Smith

IPC: G01N21/65 ,  G01J3/12 ,  G01J3/44 ,  G02B21/00

CPC classification number: B82Y15/00 ,  G01J3/44 ,  G02B21/004 ,  G02B21/008 ,  G01J2003/1226

Abstract: A sample (14) is illuminated by light from a laser source (16), which is reflected to it by a dichroic filter (18) and passed through a microscope objective (20). The microscope objective (20) focusses a two dimensional image of the illuminated area onto a detector (22). On the way to the detector (22), the light passes through an interference filter (26), which selects a desired line from the Raman spectrum scattered by the sample (14). The filter (26) can be tuned to any desired Raman line by rotating it through various angles of incidence (.THETA.), about an axis (28) perpendicular to the optical axis.

Abstract translation: PCT No.PCT / GB89 / 01532 Sec。 371日期1990年8月6日 102（e）日1990年8月6日PCT 1989年12月22日PCT公布。 出版物WO90 / 07108 日期为1990年6月28日。样品（14）由来自激光源（16）的光照射，其被二向色滤光器（18）反射并通过显微镜物镜（20）。 显微镜物镜（20）将照明区域的二维图像聚焦到检测器（22）上。 在到达检测器（22）的途中，光通过干涉滤光器（26），其从由样品（14）散射的拉曼光谱中选择所需的线。 过滤器（26）可以通过绕垂直于光轴的轴线（28）将其旋转穿过各种入射角（THETA）而被调谐到任何所需的拉曼线。

公开(公告)号：US5689333A

公开(公告)日：1997-11-18

申请号：US438270

申请日：1995-05-10

Applicant: David N. Batchelder ,  Chunwei Cheng ,  Brian J. E. Smith ,  Raymond J. Chaney

Inventor： David N. Batchelder ,  Chunwei Cheng ,  Brian J. E. Smith ,  Raymond J. Chaney

IPC: G01J3/12 ,  G01J3/18 ,  G01J3/26 ,  G01J3/28 ,  G01J3/44 ,  G02B21/00

CPC classification number: G01J3/12 ,  G01J3/2803 ,  G01J3/44 ,  G02B21/004 ,  G02B21/008 ,  B82Y35/00 ,  G01J2003/1226 ,  G01J2003/123 ,  G01J3/18 ,  G01J3/26

Abstract: A sample placed under a microscope is illuminated by light from a laser beam. Raman scattered light is passed back via a dichroic filter to various optical components which analyse the Raman spectrum, and thence to a CCD detector. The optical components for analysing the Raman spectrum include tunable dielectric filters in a filter wheel; a Fabry-Perot etalon; and a diffraction grating. These various components may be swapped into the optical path as desired, for example using movable mirrors, enabling the apparatus to be used very flexibly for a variety of different analysis procedures. Various novel analysis methods are also described.

Abstract translation: 置于显微镜下的样品由来自激光束的光照射。 拉曼散射光通过二向色滤光器返回到分析拉曼光谱的各种光学部件，然后到CCD检测器。 用于分析拉曼光谱的光学部件包括滤光轮中的可调介质滤光器; 法布里 - 珀罗标准具; 和衍射光栅。 这些各种组件可以根据需要被交换到光路中，例如使用可移动反射镜，使得能够非常灵活地使用该设备用于各种不同的分析过程。 还描述了各种新颖的分析方法。

公开(公告)号：US5623342A

公开(公告)日：1997-04-22

申请号：US656691

申请日：1996-05-31

Applicant: Kurt J. Baldwin ,  Chunwei Cheng ,  Ian P. Hayward ,  David N. Batchelder

Inventor： Kurt J. Baldwin ,  Chunwei Cheng ,  Ian P. Hayward ,  David N. Batchelder

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/44

Abstract: In a Raman microscope, Raman scattered light from an illuminated area on a sample 10 is collected by an objective 12 and imaged by a lens 18 onto a detector in an image plane 20. A filter 16 selects only light of a desired Raman wavenumber shift. Since the tuning of this filter is sensitive to the angle of incidence, it is placed after the lens 18 instead of before it, and the distance from the objective 12 to the lens 18 is made substantially equal to the focal length of the lens 18. This ensures that chief rays 14A',14B' from different points on the sample 10 pass through the filter 16 at the same angle of incidence. The wavenumber selected by the filter is therefore the same for light from all points on the sample, which it would not be if the filter were placed before the lens 18.

Abstract translation: 在拉曼显微镜中，来自样品10上的照明区域的散射光的拉曼由物镜12收集并由透镜18成像到图像平面20中的检测器上。滤光器16仅选择期望的拉曼波数位移的光。 由于该滤光器的调谐对入射角敏感，因此将其放置在透镜18之后，而不是在透镜18之前，并且从物镜12到透镜18的距离基本上等于透镜18的焦距。 这确保了来自样品10上不同点的主光线14A'，14B'以相同的入射角穿过滤光器16。 因此，过滤器所选择的波数对于样品上的所有点的光是相同的，如果将滤光片放置在透镜18之前，则不会是这样。

公开(公告)号：US5442438A

公开(公告)日：1995-08-15

申请号：US976513

申请日：1992-11-13

Applicant: David N. Batchelder ,  Chunwei Cheng

Inventor： David N. Batchelder ,  Chunwei Cheng

IPC: G01J3/12 ,  G01J3/18 ,  G01J3/26 ,  G01J3/28 ,  G01J3/44 ,  G02B21/00

CPC classification number: G01J3/12 ,  G01J3/2803 ,  G01J3/44 ,  G02B21/004 ,  G02B21/008 ,  B82Y35/00 ,  G01J2003/1226 ,  G01J2003/123 ,  G01J3/18 ,  G01J3/26

Abstract: A sample placed under a microscope is illuminated by light from a laser beam. Raman scattered light is passed back via a dichroic filter to various optical components which analyse the Raman spectrum, and thence to a CCD detector. The optical components for analysing the Raman spectrum include tunable dielectric filters in a filter wheel; a Fabry-Perot etalon; and a diffraction grating. These various components may be swapped into the optical path as desired, for example using movable mirrors, enabling the apparatus to be used very flexibly for a variety of different analysis procedures. Various novel analysis methods are also described.

Abstract translation: 置于显微镜下的样品由来自激光束的光照射。 拉曼散射光通过二向色滤光器返回到分析拉曼光谱的各种光学部件，然后到CCD检测器。 用于分析拉曼光谱的光学部件包括滤光轮中的可调介质滤光器; 法布里 - 珀罗标准具; 和衍射光栅。 这些各种组件可以根据需要被交换到光路中，例如使用可移动反射镜，使得能够非常灵活地使用该设备用于各种不同的分析过程。 还描述了各种新颖的分析方法。