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公开(公告)号：US20110130431A1
公开(公告)日：2011-06-02
申请号：US13022866
申请日：2011-02-08
Applicant: Angela BERRY , Pier Francesco CIRILLO , Eugene Richard HICKEY , Doris RIETHER , David THOMSON , Renee M. ZINDELL , Nigel BLUMIRE , Chandana CHOWDHURY , Monika ERMANN , James Edward JENKINS , Innocent MUSHI , Christopher Francis PALMER , Malcolm TAYLOR
Inventor： Angela BERRY , Pier Francesco CIRILLO , Eugene Richard HICKEY , Doris RIETHER , David THOMSON , Renee M. ZINDELL , Nigel BLUMIRE , Chandana CHOWDHURY , Monika ERMANN , James Edward JENKINS , Innocent MUSHI , Christopher Francis PALMER , Malcolm TAYLOR
IPC: A61K31/42 , C07D261/14 , C07D277/46 , C07D231/40 , C07D213/75 , C07C233/07 , C07D277/82 , C07D409/04 , C07D217/22 , A61K31/426 , A61K31/415 , A61K31/44 , A61K31/167 , A61K31/428 , A61K31/472 , A61P29/00
CPC classification number: C07C317/44 , C07D213/75 , C07D215/38 , C07D217/22 , C07D231/40 , C07D261/12 , C07D277/46 , C07D277/82 , C07D309/04 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/04 , C07D413/12 , C07D417/12
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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公开(公告)号：US09315454B2
公开(公告)日：2016-04-19
申请号：US13521246
申请日：2011-01-11
Applicant: Alessandra Bartolozzi , Angela Berry , Doris Riether , Monika Ermann , James Edward Jenkins , Innocent Mushi
Inventor： Alessandra Bartolozzi , Angela Berry , Doris Riether , Monika Ermann , James Edward Jenkins , Innocent Mushi
IPC: C07C317/06 , A61K31/165 , C07C323/41 , C07C317/44 , C07D211/54 , C07D213/40 , C07D261/08 , C07D265/30 , C07D295/185 , C07D295/205 , C07D309/04 , C07D333/20 , C07D333/38 , C07D413/12
CPC classification number: C07C323/41 , C07C317/44 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/54 , C07D213/40 , C07D261/08 , C07D265/30 , C07D295/185 , C07D295/205 , C07D309/04 , C07D333/20 , C07D333/38 , C07D413/12
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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公开(公告)号：US08829034B2
公开(公告)日：2014-09-09
申请号：US13022866
申请日：2011-02-08
Applicant: Angela Berry , Pier Francesco Cirillo , Eugene Richard Hickey , Doris Riether , David Thomson , Renee M. Zindell , Nigel Blumire , Chandana Parke , Monika Ermann , James Edward Jenkins , Innocent Mushi , Christopher Francis Palmer , Malcolm Taylor
Inventor： Angela Berry , Pier Francesco Cirillo , Eugene Richard Hickey , Doris Riether , David Thomson , Renee M. Zindell , Nigel Blumire , Chandana Parke , Monika Ermann , James Edward Jenkins , Innocent Mushi , Christopher Francis Palmer , Malcolm Taylor
IPC: C07D409/04 , C07D309/02 , A61K31/351 , A61K31/42 , C07D261/12 , C07D217/22 , C07D277/82 , C07D309/04 , C07D277/46 , C07C317/44 , C07D213/75 , C07D417/12 , C07D407/12 , C07D405/12 , C07D413/12 , C07D215/38 , C07D403/12 , C07D231/40
CPC classification number: C07C317/44 , C07D213/75 , C07D215/38 , C07D217/22 , C07D231/40 , C07D261/12 , C07D277/46 , C07D277/82 , C07D309/04 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/04 , C07D413/12 , C07D417/12
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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Patent Agency Ranking
公开(公告)号：US20120316173A1
公开(公告)日：2012-12-13
申请号：US13521246
申请日：2011-01-11
Applicant: Alessandra Bartolozzi , Angela Berry , Doris Riether , Monika Ermann , James Edward Jenkins , Innocent Mushi
Inventor： Alessandra Bartolozzi , Angela Berry , Doris Riether , Monika Ermann , James Edward Jenkins , Innocent Mushi
IPC: A61K31/164 , A61K31/165 , C07D333/20 , A61K31/381 , C07D295/192 , A61K31/495 , C07D295/205 , C07D265/30 , A61K31/5375 , C07D211/54 , A61K31/445 , C07D409/06 , A61K31/496 , C07D309/06 , A61K31/351 , C07D261/08 , A61K31/422 , A61K31/42 , C07D413/12 , A61P37/06 , A61P9/10 , A61P37/08 , A61P17/00 , A61P13/12 , A61P11/04 , A61P29/00 , A61P25/06 , C07C317/44
CPC classification number: C07C323/41 , C07C317/44 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/54 , C07D213/40 , C07D261/08 , C07D265/30 , C07D295/185 , C07D295/205 , C07D309/04 , C07D333/20 , C07D333/38 , C07D413/12
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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公开(公告)号：US07935715B2
公开(公告)日：2011-05-03
申请号：US11781336
申请日：2007-07-23
Applicant: Angela Berry , Pier Francesco Cirillo , Eugene Richard Hickey , Doris Riether , David S. Thomson , Monika Ermann , James Edward Jenkins , Innocent Mushi , Malcolm Taylor , Christopher Francis Palmer , Nigel Blumire
Inventor： Angela Berry , Pier Francesco Cirillo , Eugene Richard Hickey , Doris Riether , David S. Thomson , Monika Ermann , James Edward Jenkins , Innocent Mushi , Malcolm Taylor , Christopher Francis Palmer , Nigel Blumire
IPC: C07D213/75 , C07D403/12 , A61K31/44 , A61P29/00 , A61P37/00 , C07C317/44 , C07C215/38 , C07D217/22 , C07D231/40 , C07D261/12 , C07D277/46 , C07D277/82 , C07D309/04 , C07D405/12 , C07D407/12
CPC classification number: C07D261/14 , C07C317/44 , C07D213/75 , C07D215/38 , C07D217/22 , C07D231/40 , C07D233/88 , C07D235/30 , C07D249/14 , C07D261/20 , C07D263/28 , C07D263/58 , C07D271/07 , C07D271/113 , C07D277/46 , C07D277/56 , C07D277/60 , C07D277/82 , C07D285/08 , C07D285/135 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/04 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12 , C07D417/14
Abstract: Compound of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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公开(公告)号：US07928123B2
公开(公告)日：2011-04-19
申请号：US11854607
申请日：2007-09-13
Applicant: Angela Berry , Pier Francesco Cirillo , Doris Riether , David Thomson , Renee M. Zindell , Nigel Blumire , Chandana Chowdhury , Monika Ermann , James Edward Jenkins , Innocent Mushi , Christopher Francis Palmer , Malcolm Taylor
Inventor： Angela Berry , Pier Francesco Cirillo , Doris Riether , David Thomson , Renee M. Zindell , Nigel Blumire , Chandana Chowdhury , Monika Ermann , James Edward Jenkins , Innocent Mushi , Christopher Francis Palmer , Malcolm Taylor
IPC: C07D213/02 , A61K31/44
CPC classification number: C07C317/44 , C07D213/75 , C07D215/38 , C07D217/22 , C07D231/40 , C07D261/12 , C07D277/46 , C07D277/82 , C07D309/04 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/04 , C07D413/12 , C07D417/12
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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公开(公告)号：US08299111B2
公开(公告)日：2012-10-30
申请号：US12956322
申请日：2010-11-30
Applicant: Angela Berry , Pier Francesco Cirillo , Eugene Richard Hickey , Doris Riether , David S. Thomson , Monika Ermann , James Edward Jenkins , Innocent Mushi , Christopher Francis Palmer , Nigel Blumire
Inventor： Angela Berry , Pier Francesco Cirillo , Eugene Richard Hickey , Doris Riether , David S. Thomson , Monika Ermann , James Edward Jenkins , Innocent Mushi , Christopher Francis Palmer , Nigel Blumire
IPC: A61K31/415 , C07D231/10
CPC classification number: C07D261/14 , C07C317/44 , C07D213/75 , C07D215/38 , C07D217/22 , C07D231/40 , C07D233/88 , C07D235/30 , C07D249/14 , C07D261/20 , C07D263/28 , C07D263/58 , C07D271/07 , C07D271/113 , C07D277/46 , C07D277/56 , C07D277/60 , C07D277/82 , C07D285/08 , C07D285/135 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/04 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12 , C07D417/14
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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公开(公告)号：US20110071127A1
公开(公告)日：2011-03-24
申请号：US12956322
申请日：2010-11-30
Applicant: Angela BERRY , Pier Francesco CIRILLO , Eugene Richard HICKEY , Doris RIETHER , David THOMSON , Monika ERMANN , James Edward JENKINS , Innocent MUSHI , Malcolm TAYLOR , Chandana CHOWDHURY , Christopher Francis PALMER , Nigel BLUMIRE
Inventor： Angela BERRY , Pier Francesco CIRILLO , Eugene Richard HICKEY , Doris RIETHER , David THOMSON , Monika ERMANN , James Edward JENKINS , Innocent MUSHI , Malcolm TAYLOR , Chandana CHOWDHURY , Christopher Francis PALMER , Nigel BLUMIRE
IPC: A61K31/5377 , C07D261/14 , A61K31/42 , C07D213/70 , A61K31/4402 , C07C321/28 , A61K31/216 , C07D277/36 , A61K31/426 , C07D413/12 , A61K31/4439 , C07D309/08 , A61K31/351 , C07D417/14 , C07D413/14 , A61P29/00 , A61P1/00 , A61P25/28 , A61P35/00 , A61P37/06
CPC classification number: C07D261/14 , C07C317/44 , C07D213/75 , C07D215/38 , C07D217/22 , C07D231/40 , C07D233/88 , C07D235/30 , C07D249/14 , C07D261/20 , C07D263/28 , C07D263/58 , C07D271/07 , C07D271/113 , C07D277/46 , C07D277/56 , C07D277/60 , C07D277/82 , C07D285/08 , C07D285/135 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/04 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12 , C07D417/14
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Abstract translation: 公开了式（I）的化合物。 根据本发明的化合物结合并且是CB 2受体的激动剂，拮抗剂或反向激动剂，并且可用于治疗炎症。 作为激动剂的那些化合物另外可用于治疗疼痛。
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