公开(公告)号：US20130026079A1

公开(公告)日：2013-01-31

申请号：US13632724

申请日：2012-10-01

Applicant: Christopher B. DAVIS ,  Norbert D. HAGEN ,  James T. TUGGLE

Inventor： Christopher B. DAVIS ,  Norbert D. HAGEN ,  James T. TUGGLE

IPC: B03C1/00

CPC classification number: B01L3/52 ,  B01L3/561 ,  B01L9/52 ,  B01L2300/0609 ,  B01L2300/12 ,  B03C1/0332 ,  B03C1/12 ,  B03C1/14 ,  B03C1/28 ,  B03C1/286 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  B25J11/00 ,  B65B3/04 ,  C12N15/1013 ,  G01N35/0098 ,  Y10T29/49815

Abstract: Methods, systems, and apparatus are provided for automated isolation of selected analytes, to which magnetically-responsive solid supports are bound, from other components of a sample. An apparatus for performing an automated magnetic separation procedure includes a mechanism for effecting linear movement of a magnet between operative and non-operative positions with respect to a receptacle device. A receptacle holding station within which a receptacle device may be temporarily stored prior to moving the receptacle to the apparatus for performing magnetic separation includes magnets for applying a magnetic field to the receptacle device held therein, thereby drawing at least a proton of the magnetically-responsive solid supports out of suspension before the receptacle device is moved to the magnetic separation station. An automated receptacle transport mechanism moves the receptacle devices between the apparatus for performing magnetic separation and the receptacle holding station.

Abstract translation: 提供了方法，系统和装置，用于自动分离来自样品的其它组分的选定的分析物，其中磁性响应性固体支持物被结合。 用于执行自动磁分离程序的装置包括用于在相对于插座装置的操作位置和非操作位置之间实现磁体的线性移动的机构。 在将容器移动到用于执行磁性分离的装置之前可以临时存储插座装置的容器保持站包括用于向保持在其中的插座装置施加磁场的磁体，从而至少吸取磁响应的质子 在插座装置移动到磁选分离台之前，固体支撑体不能悬挂。 自动插座传送机构使插座装置在用于执行磁分离的装置和插座保持台之间移动。

公开(公告)号：US08276762B2

公开(公告)日：2012-10-02

申请号：US12781425

申请日：2010-05-17

Applicant: Christopher B. Davis ,  Norbert D. Hagen ,  James T. Tuggle

Inventor： Christopher B. Davis ,  Norbert D. Hagen ,  James T. Tuggle

IPC: B03C1/00

CPC classification number: B01L3/52 ,  B01L3/561 ,  B01L9/52 ,  B01L2300/0609 ,  B01L2300/12 ,  B03C1/0332 ,  B03C1/12 ,  B03C1/14 ,  B03C1/28 ,  B03C1/286 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  B25J11/00 ,  B65B3/04 ,  C12N15/1013 ,  G01N35/0098 ,  Y10T29/49815

Abstract: Methods, systems, and apparatus are provided for automated isolation of selected analytes, to which magnetically-responsive solid supports are bound, from other components of a sample. An apparatus for performing an automated magnetic separation procedure includes a mechanism for effecting linear movement of a magnet between operative and non-operative positions with respect to a receptacle device. A receptacle holding station within which a receptacle device may be temporarily stored prior to moving the receptacle to the apparatus for performing magnetic separation includes magnets for applying a magnetic field to the receptacle device held therein, thereby drawing at least a proton of the magnetically-responsive solid supports out of suspension before the receptacle device is moved to the magnetic separation station. An automated receptacle transport mechanism moves the receptacle devices between the apparatus for performing magnetic separation and the receptacle holding station.

Abstract translation: 提供了方法，系统和装置，用于自动分离来自样品的其它组分的选定的分析物，其中磁性响应性固体支持物被结合。 用于执行自动磁分离程序的装置包括用于在相对于插座装置的操作位置和非操作位置之间实现磁体的线性移动的机构。 在将容器移动到用于执行磁性分离的装置之前可以临时存储插座装置的容器保持站包括用于向保持在其中的插座装置施加磁场的磁体，从而至少吸取磁响应的质子 在插座装置移动到磁选分离台之前，固体支撑体不能悬挂。 自动插座传送机构使插座装置在用于执行磁分离的装置和插座保持台之间移动。

公开(公告)号：US20100294047A1

公开(公告)日：2010-11-25

申请号：US12781425

申请日：2010-05-17

Applicant: Christopher B. Davis ,  Norbert D. Hagen ,  James T. Tuggle

Inventor： Christopher B. Davis ,  Norbert D. Hagen ,  James T. Tuggle

IPC: G01N1/10

CPC classification number: B01L3/52 ,  B01L3/561 ,  B01L9/52 ,  B01L2300/0609 ,  B01L2300/12 ,  B03C1/0332 ,  B03C1/12 ,  B03C1/14 ,  B03C1/28 ,  B03C1/286 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  B25J11/00 ,  B65B3/04 ,  C12N15/1013 ,  G01N35/0098 ,  Y10T29/49815

Abstract: Methods, systems, and apparatus are provided for automated isolation of selected analytes, to which magnetically-responsive solid supports are bound, from other components of a sample. An apparatus for performing an automated magnetic separation procedure includes a mechanism for effecting linear movement of a magnet between operative and non-operative positions with respect to a receptacle device. A receptacle holding station within which a receptacle device may be temporarily stored prior to moving the receptacle to the apparatus for performing magnetic separation includes magnets for applying a magnetic field to the receptacle device held therein, thereby drawing at least a proton of the magnetically-responsive solid supports out of suspension before the receptacle device is moved to the magnetic separation station. An automated receptacle transport mechanism moves the receptacle devices between the apparatus for performing magnetic separation and the receptacle holding station.

Abstract translation: 提供了方法，系统和装置，用于自动分离来自样品的其它组分的选定的分析物，其中磁性响应性固体支持物被结合。 用于执行自动磁分离程序的装置包括用于在相对于插座装置的操作位置和非操作位置之间实现磁体的线性移动的机构。 在将容器移动到用于执行磁性分离的装置之前可以临时存储插座装置的容器保持站包括用于向保持在其中的插座装置施加磁场的磁体，从而至少吸取磁响应的质子 在插座装置移动到磁选分离台之前，固体支撑体不能悬挂。 自动插座传送机构使插座装置在用于执行磁分离的装置和插座保持台之间移动。

公开(公告)号：US08844731B2

公开(公告)日：2014-09-30

申请号：US13632724

申请日：2012-10-01

Applicant: Christopher B. Davis ,  Norbert D. Hagen ,  James T. Tuggle

Inventor： Christopher B. Davis ,  Norbert D. Hagen ,  James T. Tuggle

IPC: B03C1/00 ,  B03C1/033 ,  B03C1/28

CPC classification number: B01L3/52 ,  B01L3/561 ,  B01L9/52 ,  B01L2300/0609 ,  B01L2300/12 ,  B03C1/0332 ,  B03C1/12 ,  B03C1/14 ,  B03C1/28 ,  B03C1/286 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  B25J11/00 ,  B65B3/04 ,  C12N15/1013 ,  G01N35/0098 ,  Y10T29/49815

Abstract: Methods, systems, and apparatus are provided for automated isolation of selected analytes, to which magnetically-responsive solid supports are bound, from other components of a sample. An apparatus for performing an automated magnetic separation procedure includes a mechanism for effecting linear movement of a magnet between operative and non-operative positions with respect to a receptacle device. A receptacle holding station within which a receptacle device may be temporarily stored prior to moving the receptacle to the apparatus for performing magnetic separation includes magnets for applying a magnetic field to the receptacle device held therein, thereby drawing at least a proton of the magnetically-responsive solid supports out of suspension before the receptacle device is moved to the magnetic separation station. An automated receptacle transport mechanism moves the receptacle devices between the apparatus for performing magnetic separation and the receptacle holding station.

Abstract translation: 提供了方法，系统和装置，用于自动分离来自样品的其它组分的选定的分析物，其中磁性响应性固体支持物被结合。 用于执行自动磁分离程序的装置包括用于在相对于插座装置的操作位置和非操作位置之间实现磁体的线性移动的机构。 在将容器移动到用于执行磁性分离的装置之前可以临时存储插座装置的容器保持站包括用于向保持在其中的插座装置施加磁场的磁体，从而至少吸取磁响应的质子 在插座装置移动到磁选分离台之前，固体支撑体不能悬挂。 自动插座传送机构使插座装置在用于执行磁分离的装置和插座保持台之间移动。