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    4(1H)-quinolones having antimalarial activity with reduced chemical resistance
    1.
    发明授权
    4(1H)-quinolones having antimalarial activity with reduced chemical resistance 有权
    4（1H） - 具有抗疟活性并具有降低的耐药性的喹诺酮类

    公开(公告)号：US08877752B2

    公开(公告)日：2014-11-04

    申请号：US13661300

    申请日：2012-10-26

    Applicant: Roman Manetsch ,  Richard Matthew Cross ,  Niranjan Kumar Namelikonda ,  Dennis Edward Kyle ,  Tina Susanna Mutka ,  Alexis Nichole LaCrue ,  Jordany Richarlson Maignan ,  Fabian Ernesto Saenz

    Inventor： Roman Manetsch ,  Richard Matthew Cross ,  Niranjan Kumar Namelikonda ,  Dennis Edward Kyle ,  Tina Susanna Mutka ,  Alexis Nichole LaCrue ,  Jordany Richarlson Maignan ,  Fabian Ernesto Saenz

    IPC: C07D215/233 ,  C07D413/04 ,  C07D401/04 ,  C07D215/56

    CPC classification number: C07D215/233 ,  C07D215/56 ,  C07D401/04 ,  C07D413/04

    Abstract: Provided are 4(1H)-quinolone derivatives effective in inhibiting or eliminating the viability of at least one of the stages in the life-cycle of the malarial parasite, and to show a reduced propensity to induce resistance to the compound by the target parasite. In particular, the compounds can be derivatives of phenoxyethoxy-quinolones, and including, but not only, 7-(2-phenoxyethoxy)quinolin derivatives. These compounds may be administered by themselves, with at least one other derivative compound, or with other antimalarial compounds, to an animal or human subject. The therapeutic compositions can be and formulated to reduce the extent of a Plasmodium infection in the recipient subject, or to reduce the likelihood of the onset or establishment of a Plasmodium infection if administered prior to the parasite contacting the subject. The therapeutic compositions can be formulated to provide an effective single dose amount of an antimalarial compound or multiple doses for administering over a period of time.

    Abstract translation: 提供了有效抑制或消除疟疾寄生虫生命周期中的至少一个阶段的存活力的4（1H） - 喹诺酮衍生物，并且显示降低由靶寄生虫诱导对化合物的抗性的倾向。 特别地，所述化合物可以是苯氧基乙氧基 - 喹诺酮的衍生物，并且包括但不限于7-（2-苯氧基乙氧基）喹啉衍生物。 这些化合物可以自身与至少一种其它衍生化合物或与其它抗疟药化合物一起施用于动物或人类受试者。 治疗组合物可以并配制成减少接受者受试者中疟原虫感染的程度，或者如果在寄生虫接触受试者之前施用，则降低发生或建立疟原虫感染的可能性。 治疗组合物可以配制成提供有效的单次剂量的抗疟药化合物或多个剂量用于一段时间的给药。

    Obstacle following sensor scheme for a mobile robot
    2.
    发明授权
    Obstacle following sensor scheme for a mobile robot 有权
    障碍物用于移动机器人的传感器方案

    公开(公告)号：US08788092B2

    公开(公告)日：2014-07-22

    申请号：US11834573

    申请日：2007-08-06

    Applicant: Christopher M. Casey ,  Matthew Cross ,  Daniel N. Ozick ,  Joseph L. Jones

    Inventor： Christopher M. Casey ,  Matthew Cross ,  Daniel N. Ozick ,  Joseph L. Jones

    IPC: G06F19/00 ,  G05D1/02

    CPC classification number: G05D1/0238

    Abstract: A robot obstacle detection system including a robot housing which navigates with respect to a surface and a sensor subsystem aimed at the surface for detecting the surface. The sensor subsystem includes an emitter which emits a signal having a field of emission and a photon detector having a field of view which intersects the field of emission at a region. The subsystem detects the presence of an object proximate the mobile robot and determines a value of a signal corresponding to the object. It compares the value to a predetermined value, moves the mobile robot in response to the comparison, and updates the predetermined value upon the occurrence of an event.

    Abstract translation: 一种机器人障碍物检测系统，包括相对于表面导航的机器人壳体和用于检测表面的表面的传感器子系统。 传感器子系统包括发射具有发射场的信号的发射器和具有与区域上的发射场相交的视场的光子检测器。 子系统检测邻近移动机器人的对象的存在并且确定与对象相对应的信号的值。 它将该值与预定值进行比较，响应比较移动移动机器人，并且在事件发生时更新预定值。

    Mobile robot for telecommunication
    4.
    发明授权
    Mobile robot for telecommunication 有权
    移动机器人电信

    公开(公告)号：US08577501B2

    公开(公告)日：2013-11-05

    申请号：US13562315

    申请日：2012-07-31

    Applicant: Matthew Cross ,  Tony Campbell

    Inventor： Matthew Cross ,  Tony Campbell

    IPC: G05B19/00

    CPC classification number: B25J11/0005 ,  G05D1/0022 ,  G05D2201/0211 ,  H04L67/10 ,  H04N7/15 ,  H04N21/4788 ,  H04W4/70 ,  Y10S901/01 ,  Y10S901/02 ,  Y10S901/17 ,  Y10S901/27 ,  Y10S901/47

    Abstract: A remote control unit configured to wirelessly control a mobile robot moving through an environment and having a robot camera. The remote control unit comprises a privacy button operable by a local user and configured to engage a privacy mode of the mobile robot, and a wireless transmitter configured to emit a wireless control signal to the mobile robot based on input from a keypad of the RC unit. The wireless control signal is configured to cause the robot camera to block the field of view of the robot camera such that the environment of the mobile robot is obscured when the privacy mode of the mobile robot is engaged.

    Abstract translation: 远程控制单元，被配置为无线地控制移动机器人移动通过环境并具有机器人相机。 远程控制单元包括由本地用户操作并被配置为参与移动机器人的隐私模式的隐私按钮，以及被配置为基于来自RC单元的键盘的输入向移动机器人发送无线控制信号的无线发射器 。 无线控制信号被配置为使得机器人相机阻挡机器人相机的视野，使得当移动机器人的隐私模式被接合时移动机器人的环境被遮蔽。

    Obstacle following sensor scheme for a mobile robot
    7.
    发明授权
    Obstacle following sensor scheme for a mobile robot 有权

    公开(公告)号：US08275482B2

    公开(公告)日：2012-09-25

    申请号：US12126757

    申请日：2008-05-23

    Applicant: Christopher Casey ,  Matthew Cross ,  Daniel Ozick ,  Joseph L. Jones

    Inventor： Christopher Casey ,  Matthew Cross ,  Daniel Ozick ,  Joseph L. Jones

    IPC: G06F19/00

    Abstract: A robot obstacle detection system including a robot housing which navigates with respect to a surface and a sensor subsystem aimed at the surface for detecting the surface. The sensor subsystem includes an emitter which emits a signal having a field of emission and a photon detector having a field of view which intersects the field of emission at a region. The subsystem detects the presence of an object proximate the mobile robot and determines a value of a signal corresponding to the object. It compares the value to a predetermined value, moves the mobile robot in response to the comparison, and updates the predetermined value upon the occurrence of an event.

    Obstacle following sensor scheme for a mobile robot
    10.
    发明申请
    Obstacle following sensor scheme for a mobile robot 有权
    障碍物用于移动机器人的传感器方案

    公开(公告)号：US20050251292A1

    公开(公告)日：2005-11-10

    申请号：US11166986

    申请日：2005-06-24

    Applicant: Christopher Casey ,  Matthew Cross ,  Daniel Ozick ,  Joseph Jones

    Inventor： Christopher Casey ,  Matthew Cross ,  Daniel Ozick ,  Joseph Jones

    IPC: G05D1/02 ,  G06F19/00

    CPC classification number: B25J9/1697 ,  A47L2201/04 ,  G01S15/931 ,  G01S17/93 ,  G05D1/0238 ,  G05D1/024 ,  G05D1/0242 ,  G05D1/0255 ,  G05D2201/0203 ,  G05D2201/0208 ,  G05D2201/0215 ,  Y02P90/265 ,  Y10S901/01 ,  Y10S901/47

    Abstract: A robot obstacle detection system including a robot housing which navigates with respect to a surface and a sensor subsystem aimed at the surface for detecting the surface. The sensor subsystem includes an emitter which emits a signal having a field of emission and a photon detector having a field of view which intersects the field of emission at a region. The subsystem detects the presence of an object proximate the mobile robot and determines a value of a signal corresponding to the object. It compares the value to a predetermined value, moves the mobile robot in response to the comparison, and updates the predetermined value upon the occurrence of an event.

    Abstract translation: 一种机器人障碍物检测系统，包括相对于表面导航的机器人壳体和用于检测表面的表面的传感器子系统。 传感器子系统包括发射具有发射场的信号的发射器和具有与区域上的发射场相交的视场的光子检测器。 子系统检测邻近移动机器人的对象的存在并且确定与对象相对应的信号的值。 它将该值与预定值进行比较，响应比较移动移动机器人，并且在事件发生时更新预定值。

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