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公开(公告)号：US09304088B2
公开(公告)日：2016-04-05
申请号：US13400106
申请日：2012-02-19
Applicant: Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
Inventor： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
CPC classification number: G01N21/80 , C12M41/26 , G01N21/3151 , G01N31/221 , G01N2201/0627 , G01N2201/1211
Abstract: A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.
Abstract translation: 测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在所述测量区域的另一侧上接收所发射的光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。
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公开(公告)号：US20120252110A1
公开(公告)日：2012-10-04
申请号：US13432658
申请日：2012-03-28
Applicant: Mitsuhiro OURA , Teruo OKANO , Tatsuya SHIMIZU , Hirotsugu KUBO , Sunao TAKEDA
Inventor： Mitsuhiro OURA , Teruo OKANO , Tatsuya SHIMIZU , Hirotsugu KUBO , Sunao TAKEDA
Abstract: A cell culture apparatus includes: an isolator in which a sterile space accommodating a cell incubator filled with a culture solution containing cells to be cultured is disposed; a sampling unit configured to sample the culture solution in the cell incubator; a delivery flow path through which an inside of the sterile space and an outside of the sterile space communicate with each other, the delivery flow path configured to limit a flow in the delivery flow path to a direction that is directed from the inside of the sterile space toward the outside of the sterile space; and a culture solution delivering section configured to deliver the sampled culture solution to the outside of the sterile space via the delivery flow path.
Abstract translation: 细胞培养装置包括：隔离器，其中设置容纳装有包含待培养细胞的培养液的细胞培养箱的无菌空间; 取样单元，其构造为对细胞培养器中的培养液进行取样; 输送流动路径，无菌空间的内部和无菌空间的外部通过其彼此连通，输送流路被配置为将输送流动路径中的流动限制到从无菌空间的内部指向的方向 空间朝无菌空间外面; 以及培养液输送部，其构造成经由所述输送流路将取样的培养液输送到所述无菌空间的外部。
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Patent Agency Ranking
公开(公告)号：US20120214250A1
公开(公告)日：2012-08-23
申请号：US13400106
申请日：2012-02-19
Applicant: Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
Inventor： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
IPC: G01N21/59
CPC classification number: G01N21/80 , C12M41/26 , G01N21/3151 , G01N31/221 , G01N2201/0627 , G01N2201/1211
Abstract: A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances ; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.
Abstract translation: 测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在测量区域的另一侧上接收发射光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。
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公开(公告)号：US09291572B2
公开(公告)日：2016-03-22
申请号：US13441630
申请日：2012-04-06
Applicant: Mitsuhiro Oura , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
Inventor： Mitsuhiro Oura , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
CPC classification number: G01N21/80 , C12M41/26 , G01N31/221 , G01N2021/3148 , G01N2021/3181 , G01N2201/0627
Abstract: A pH measuring method includes: illuminating a medium solution, which includes: a first material; and a second material, with a plurality of light beams, which includes: a first light beam, a wavelength of which corresponds to a first absorption peak; a second light beam, a wavelength of which corresponds to a second absorption peak or a second convergence point; a third light beam, a wavelength of which corresponds to a third absorption peak or a third convergence point; and a fourth light beam, a wavelength of the fourth light beam at which an absorbance of at least one of the first and second materials is converged irrespective of a pH; receiving transmitted or reflected light beams of the first to fourth light beams; measuring absorbances at the wavelengths of the received light beams respectively; and calculating a pH of the medium solution based on the absorbances.
Abstract translation: pH测量方法包括：照射介质溶液，其包括：第一材料; 以及具有多个光束的第二材料，其包括：第一光束，其波长对应于第一吸收峰; 第二光束，其波长对应于第二吸收峰或第二会聚点; 第三光束，其波长对应于第三吸收峰或第三会聚点; 以及第四光束，所述第四光束的波长，其中所述第一和第二材料中的至少一个的吸光度在不同pH下会聚; 接收第一至第四光束的透射或反射光束; 分别测量接收光束波长处的吸光度; 并基于吸光度计算介质溶液的pH。
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公开(公告)号：US09783773B2
公开(公告)日：2017-10-10
申请号：US13432658
申请日：2012-03-28
Applicant: Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda
Inventor： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda
Abstract: A cell culture apparatus includes: an isolator in which a sterile space accommodating a cell incubator filled with a culture solution containing cells to be cultured is disposed; a sampling unit configured to sample the culture solution in the cell incubator; a delivery flow path through which an inside of the sterile space and an outside of the sterile space communicate with each other, the delivery flow path configured to limit a flow in the delivery flow path to a direction that is directed from the inside of the sterile space toward the outside of the sterile space; and a culture solution delivering section configured to deliver the sampled culture solution to the outside of the sterile space via the delivery flow path.
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公开(公告)号：US20120253692A1
公开(公告)日：2012-10-04
申请号：US13441630
申请日：2012-04-06
Applicant: Mitsuhiro OURA , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
Inventor： Mitsuhiro OURA , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
CPC classification number: G01N21/80 , C12M41/26 , G01N31/221 , G01N2021/3148 , G01N2021/3181 , G01N2201/0627
Abstract: A pH measuring method includes: illuminating a medium solution, which includes: a first material; and a second material, with a plurality of light beams, which includes: a first light beam, a wavelength of which corresponds to a first absorption peak; a second light beam, a wavelength of which corresponds to a second absorption peak or a second convergence point; a third light beam, a wavelength of which corresponds to a third absorption peak or a third convergence point; and a fourth light beam, a wavelength of the fourth light beam at which an absorbance of at least one of the first and second materials is converged irrespective of a pH; receiving transmitted or reflected light beams of the first to fourth light beams; measuring absorbances at the wavelengths of the received light beams respectively; and calculating a pH of the medium solution based on the absorbances.
Abstract translation: pH测量方法包括：照射介质溶液，其包括：第一材料; 以及具有多个光束的第二材料，其包括：第一光束，其波长对应于第一吸收峰; 第二光束，其波长对应于第二吸收峰或第二会聚点; 第三光束，其波长对应于第三吸收峰或第三会聚点; 以及第四光束，所述第四光束的波长，其中所述第一和第二材料中的至少一个的吸光度在不同pH下会聚; 接收第一至第四光束的透射或反射光束; 分别测量接收光束波长处的吸光度; 并基于吸光度计算介质溶液的pH。
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公开(公告)号：US20120214225A1
公开(公告)日：2012-08-23
申请号：US13400107
申请日：2012-02-19
Applicant: Mitsuhiro OURA , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Katsuyoshi Suzuki , Sunao Takeda
Inventor： Mitsuhiro OURA , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Katsuyoshi Suzuki , Sunao Takeda
IPC: C12M3/00
Abstract: A cell incubator includes: a culture cell accommodating section which accommodates cells to be cultured and a culture solution; and an RFID tag which is attached to the culture cell accommodating section and which is configured to transmit predetermined information to a communicating apparatus in response to reception of a signal that is wirelessly transmitted from the communicating apparatus.
Abstract translation: 细胞培养箱包括：容纳待培养细胞的培养细胞容纳部分和培养液; 以及RFID标签，其附接到所述培养单元容纳部，并且被配置为响应于从所述通信装置无线发送的信号的接收，向所述通信装置发送预定信息。
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