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公开(公告)号：US09161703B2
公开(公告)日：2015-10-20
申请号：US14053639
申请日：2013-10-15
Applicant: Min-Hsien Wu , Yi-Yuan Chiu , Hsin-Yao Wang , Song-Bin Huang
Inventor： Min-Hsien Wu , Yi-Yuan Chiu , Hsin-Yao Wang , Song-Bin Huang
CPC classification number: A61B5/04 , A61B5/02438 , A61B5/02444 , A61B5/1107 , A61B5/113 , A61B5/6813 , A61B2560/0412 , A61B2560/0468 , A61B2562/0209 , A61B2562/182
Abstract: An integrated bioinformatics sensing apparatus includes a piezoelectric sensing layer, an upper conductive layer, a bottom conductive layer and an information transmission controller. The piezoelectric sensing layer senses a physiological rhythm of a living organism to output a physiological rhythm signal, and the upper and bottom conductive layers sense a physiological electrical signal on a body surface of the living organism. The information transmission controller receives and processes the physiological rhythm signal and the physiological electrical signal to generate and store the sensed bioinformatics, or transmit the signals to the external processing device to display the sensed bioinformatics. The simple-structured sensing apparatus can be attached onto the body surface of the living organism conveniently.
Abstract translation: 综合生物信息学感测装置包括压电感测层，上导电层，底导电层和信息传输控制器。 压电感测层感测生物体的生理节律以输出生理节奏信号，并且上，下导电层感测生物体的体表上的生理电信号。 信息传输控制器接收并处理生理节奏信号和生理电信号以产生和存储所感测的生物信息学，或者将信号发送到外部处理装置以显示感测的生物信息学。 简单结构的感测装置可以方便地附着在生物体的身体表面上。
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2.发明申请公开(公告)号：US20110217751A1
公开(公告)日：2011-09-08
申请号：US13064006
申请日：2011-03-02
Applicant: Gwo-Bin Lee , Song-Bin Huang , Min-Hsien Wu
Inventor： Gwo-Bin Lee , Song-Bin Huang , Min-Hsien Wu
Abstract: This present invention relates to a method for forming alginate microbeads. The method includes using a needle connected to a vibrator to continuously spot tiny alginate microdroplets in an oil layer. Subsequently, the temporarily formed alginate microdroplets sink into a CaCl2 solution to become gelled microbeads. As a whole, the method has opened up a route to perform alginate-microbead formation in a simple, continuous, controllable, uniform, cell-friendly, and less-contaminated manner.
Abstract translation: 本发明涉及一种形成藻酸盐微珠的方法。 该方法包括使用连接到振动器的针连续地在油层中发现微小的藻酸盐微滴。 随后，临时形成的藻酸盐微滴沉降成CaCl 2溶液成为胶凝微珠。 总体而言，该方法开辟了以简单，连续，可控，均匀，细胞友好且污染少的方式进行藻酸盐 - 微珠形成的途径。
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Patent Agency Ranking
3.发明申请Physiological Electrical Signal and Living Organism Movement Signal Sensing Apparatus 审中-公开生理电信号和生物活体信号传感装置公开(公告)号：US20140128688A1
公开(公告)日：2014-05-08
申请号：US14055926
申请日：2013-10-17
Applicant: Min-Hsien Wu , Yi-Yuan Chiu , Hsin-Yao Wang , Song-Bin Huang
Inventor： Min-Hsien Wu , Yi-Yuan Chiu , Hsin-Yao Wang , Song-Bin Huang
IPC: A61B5/0205 , A61B5/11 , A61B5/04 , A61B5/0408 , A61B8/08 , A61B5/0492 , A61B5/0496 , A61B5/113 , A61B5/00 , A61B8/00 , A61B8/02 , A61B5/0478
CPC classification number: A61B8/56 , A61B5/0006 , A61B5/0245 , A61B5/0408 , A61B5/1102 , A61B5/1126 , A61B5/113
Abstract: A physiological electrical signal and living organism movement signal sensing apparatus includes at least one electrode element, a piezoelectric sensing layer, a connecting layer and a control unit. The connecting layer is connected to the at least one electrode element, and the electrode element measures a physiological electrical signal of a living organism to generate a physiological sensing signal and the piezoelectric sensing layer measures a living organism movement signal to generate a living organism movement sensing signal, and the control unit receives the physiological sensing signal and the living organism movement sensing signal to determine and display the physiological status and movement of the living organism. The sensing apparatus has the features of providing highly integrated functions and simple structure.
Abstract translation: 生理电信号和生物体运动信号检测装置包括至少一个电极元件，压电感测层，连接层和控制单元。 连接层连接到至少一个电极元件，并且电极元件测量生物体的生理电信号以产生生理感测信号，并且压电感测层测量生物体运动信号以产生生物体运动感测 信号，并且控制单元接收生理感测信号和生物体运动感测信号，以确定和显示生物体的生理状态和运动。 该感测装置具有提供高度集成的功能和简单结构的特点。
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公开(公告)号：US08911989B2
公开(公告)日：2014-12-16
申请号：US12795445
申请日：2010-06-07
Applicant: Gwo-Bin Lee , Sung-Yi Yang , Song-Bin Huang , Kang-Yi Lien , Chen-Hsun Weng
Inventor： Gwo-Bin Lee , Sung-Yi Yang , Song-Bin Huang , Kang-Yi Lien , Chen-Hsun Weng
CPC classification number: F16K99/0001 , B01F11/0071 , B01F13/0059 , B01L3/50273 , B01L3/502738 , B01L7/52 , B01L2300/0819 , B01L2300/0867 , B01L2400/043 , B01L2400/049 , F16K99/0015 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , Y10T137/0396
Abstract: The present invention provides a microfluidic biochip, which comprises: a fluid transportation unit having a fluid transportation reservoir and a fluid transportation air chamber; a first fluid storage reservoir; a second fluid storage reservoir; a first valve unit having a first valve and a first valve control air chamber; and a second valve unit having a second valve and a second valve control air chamber; wherein the first valve unit is located between the first fluid storage reservoir and the fluid transportation unit, the second valve unit is located between the second fluid storage reservoir and the fluid transportation unit, and the top portion of the fluid transportation reservoir and the valves are made of a flexible material. The structure of the present microfluidic biochip allows fluids to be transported and/or mixed therein.
Abstract translation: 本发明提供了一种微流体生物芯片，其包括：流体输送单元，其具有流体输送储存器和流体输送空气室; 第一流体储存容器; 第二流体储存容器; 第一阀单元，具有第一阀和第一阀控制空气室; 以及具有第二阀和第二阀控制空气室的第二阀单元; 其中所述第一阀单元位于所述第一流体储存容器和所述流体输送单元之间，所述第二阀单元位于所述第二流体储存容器和所述流体输送单元之间，并且所述流体输送储存器的顶部和所述阀为 由柔性材料制成。 本发明微流体生物芯片的结构允许流体在其中运输和/或混合。
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公开(公告)号：US20140107452A1
公开(公告)日：2014-04-17
申请号：US14053639
申请日：2013-10-15
Applicant: Min-Hsien Wu , Yi-Yuan Chiu , Hsin-Yao Wang , Song-Bin Huang
Inventor： Min-Hsien Wu , Yi-Yuan Chiu , Hsin-Yao Wang , Song-Bin Huang
IPC: A61B5/04
CPC classification number: A61B5/04 , A61B5/02438 , A61B5/02444 , A61B5/1107 , A61B5/113 , A61B5/6813 , A61B2560/0412 , A61B2560/0468 , A61B2562/0209 , A61B2562/182
Abstract: An integrated bioinformatics sensing apparatus includes a piezoelectric sensing layer, an upper conductive layer, a bottom conductive layer and an information transmission controller. The piezoelectric sensing layer senses a physiological rhythm of a living organism to output a physiological rhythm signal, and the upper and bottom conductive layers sense a physiological electrical signal on a body surface of the living organism, and the information transmission controller receives and processes the physiological rhythm signal and the physiological electrical signal to generate and store the sensed bioinformatics, or transmit the signals to the external processing device to display the sensed bioinformatics. The simple-structured sensing apparatus can be attached onto the body surface of the living organism conveniently.
Abstract translation: 综合生物信息学感测装置包括压电感测层，上导电层，底导电层和信息传输控制器。 压电感测层感测生物体的生理节律，输出生理节奏信号，上下导电层感测生物体的体表上的生理电信号，信息传输控制器接收并处理生理 节奏信号和生理电信号以产生和存储所感测的生物信息学，或将信号发送到外部处理装置以显示所感测的生物信息学。 简单结构的感测装置可以方便地附着在生物体的身体表面上。
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公开(公告)号：US20080044894A1
公开(公告)日：2008-02-21
申请号：US11797052
申请日：2007-04-30
Applicant: Gwo-Bin Lee , Song-Bin Huang
Inventor： Gwo-Bin Lee , Song-Bin Huang
IPC: C12M1/00
Abstract: A cellular culture chip device includes a chip body. The chip body includes: a first flow channel having a first inlet end and a first outlet end and adapted to direct a liquid nutrient; a second flow channel adapted to direct a gellable culture medium; a medium retaining hole fluidly connected to the second flow channel and adapted to retain the gellable culture medium, the medium retaining hole having an opening connected fluidly to the first flow channel and adapted to expose the gellable culture medium to the liquid nutrient flowing through the first flow channel; a pump membrane adapted to control the flow of the liquid nutrient within the first flow channel; and a pressure channel unit to operate the pump membrane.
Abstract translation: 细胞培养芯片装置包括芯片体。 芯片主体包括：具有第一入口端和第一出口端并适于引导液体营养物的第一流动通道; 适于引导胶凝培养基的第二流动通道; 介质保持孔，其流体地连接到第二流动通道并且适于保持可凝胶化的培养基，所述介质保持孔具有与第一流动通道流体连接的开口，并适于将可凝胶培养基暴露于流过第一流动通道的液体营养物 流通道 泵膜，其适于控制所述第一流动通道内的液体营养物的流动; 以及用于操作泵膜的压力通道单元。
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公开(公告)号：US20110136179A1
公开(公告)日：2011-06-09
申请号：US12795445
申请日：2010-06-07
Applicant: Gwo BIN/LEE , Sung YI/YANG , Song BIN/HUANG , Kang YI/LIEN , Chen HSUN/WENG
Inventor： Gwo BIN/LEE , Sung YI/YANG , Song BIN/HUANG , Kang YI/LIEN , Chen HSUN/WENG
CPC classification number: F16K99/0001 , B01F11/0071 , B01F13/0059 , B01L3/50273 , B01L3/502738 , B01L7/52 , B01L2300/0819 , B01L2300/0867 , B01L2400/043 , B01L2400/049 , F16K99/0015 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , Y10T137/0396
Abstract: The present invention provides a microfluidic biochip, which comprises: a fluid transportation unit having a fluid transportation reservoir and a fluid transportation air chamber; a first fluid storage reservoir; a second fluid storage reservoir; a first valve unit having a first valve and a first valve control air chamber; and a second valve unit having a second valve and a second valve control air chamber; wherein the first valve unit is located between the first fluid storage reservoir and the fluid transportation unit, the second valve unit is located between the second fluid storage reservoir and the fluid transportation unit, and the top portion of the fluid transportation reservoir and the valves are made of a flexible material. The structure of the present microfluidic biochip allows fluids to be transported and/or mixed therein.
Abstract translation: 本发明提供了一种微流体生物芯片，其包括：流体输送单元，其具有流体输送储存器和流体输送空气室; 第一流体储存容器; 第二流体储存容器; 第一阀单元，具有第一阀和第一阀控制空气室; 以及具有第二阀和第二阀控制空气室的第二阀单元; 其中所述第一阀单元位于所述第一流体储存容器和所述流体输送单元之间，所述第二阀单元位于所述第二流体储存容器和所述流体输送单元之间，并且所述流体输送储存器的顶部和所述阀为 由柔性材料制成。 本发明微流体生物芯片的结构允许流体在其中运输和/或混合。
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