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1.
公开(公告)号:US08715269B2
公开(公告)日:2014-05-06
申请号:US13406514
申请日:2012-02-27
Applicant: Andy Wolff , Ben Z Beiski , Simon Herrlich , Axel Schumacher , Sven Spieth , Stephan Messner , Rachid Nouna
Inventor: Andy Wolff , Ben Z Beiski , Simon Herrlich , Axel Schumacher , Sven Spieth , Stephan Messner , Rachid Nouna
Abstract: Embodiments of the invention disclose a system for controlled oral drug delivery. The system comprising a removable device comprising a drug to be delivered, wherein the drug is delivered based on osmotic pressure generated in the removable device. Further, the system comprises a receptacle to hold the removable device in an oral cavity, and a base station configured to dock the removable device for determining information about one or more characteristics of the removable device.
Abstract translation: 本发明的实施方案公开了一种用于受控口服药物递送的系统。 该系统包括可移除装置,其包括待递送的药物,其中基于在可移除装置中产生的渗透压输送药物。 此外,该系统包括用于将可移除装置保持在口腔中的插座,以及被配置为对准可移除装置以确定关于可移除装置的一个或多个特性的信息的基站。
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2.
公开(公告)号:US20120220986A1
公开(公告)日:2012-08-30
申请号:US13406514
申请日:2012-02-27
Applicant: Andy Wolff , Ben Z Beiski , Simon Herrlich , Axel Schumacher , Sven Spieth , Stephan Messner , Rachid Nouna
Inventor: Andy Wolff , Ben Z Beiski , Simon Herrlich , Axel Schumacher , Sven Spieth , Stephan Messner , Rachid Nouna
IPC: A61M37/00
Abstract: Embodiments of the invention disclose a system for controlled oral drug delivery. The system comprising a removable device comprising a drug to be delivered, wherein the drug is delivered based on osmotic pressure generated in the removable device. Further, the system comprises a receptacle to hold the removable device in an oral cavity, and a base station configured to dock the removable device for determining information about one or more characteristics of the removable device.
Abstract translation: 本发明的实施方案公开了一种用于受控口服药物递送的系统。 该系统包括可移除装置,其包括待递送的药物,其中基于在可移除装置中产生的渗透压输送药物。 此外,该系统包括用于将可移除装置保持在口腔中的插座,以及被配置为对准可移除装置以确定关于可移除装置的一个或多个特性的信息的基站。
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公开(公告)号:US6109889A
公开(公告)日:2000-08-29
申请号:US91030
申请日:1998-06-03
Applicant: Roland Zengerle , Manfred Stehr , Stephan Messner
Inventor: Roland Zengerle , Manfred Stehr , Stephan Messner
CPC classification number: F04B43/046
Abstract: A fluid pump has a pump body and a displacer, the displacer and the pump body being implemented such that a pump chamber is defined therebetween, the pump chamber having an inlet opening and an outlet opening, neither the inlet opening nor the outlet opening being provided with a check valve. A drive means is provided which positions the displacer periodically at a first and at a second end position. The displacer closes the outlet opening when it occupies its first end position and leaves the outlet opening free when it occupies its second end position and leaves the inlet opening free at both end positions thereof. The displacer, when moving from the first to the second end position, defines a flow-through gap which opens between the displacer and the pump body in the area of the outlet opening in dependence upon the movement, the flow-through gap being defined such that the flow through the outlet opening depends on the pressure in the pump chamber as well as on the respective opening degree of the flow-through gap.
Abstract translation: PCT No.PCT / EP96 / 05382 Sec。 371日期1998年6月3日第 102(e)日期1998年6月3日PCT 1996年12月3日PCT PCT。 第WO97 / 21924号公报 日期1997年6月19日流体泵具有泵体和置换器,所述置换器和泵体被实现为在其间限定泵室,所述泵室具有入口开口和出口开口, 出口开口设有止回阀。 提供了一种驱动装置,其将置换器周期性地定位在第一和第二结束位置。 当其占据其第一端部位置时,置换器关闭出口开口,并且当其占据其第二端部位置并且使入口开口在其两个端部位置处离开时,离开出口开口自由。 当从第一位置移动到第二端位置时,置换器限定了依靠移动在出口开口的区域中在置换器和泵体之间打开的流通间隙,所述流通间隙被定义为 通过出口开口的流量取决于泵室中的压力以及流通间隙的相应开度。
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公开(公告)号:US06280148B1
公开(公告)日:2001-08-28
申请号:US09367664
申请日:1999-08-17
Applicant: Roland Zengerle , Michael Freygang , Manfred Stehr , Stephan Messner , Matthias Ashauer , Rainer Rossberg
Inventor: Roland Zengerle , Michael Freygang , Manfred Stehr , Stephan Messner , Matthias Ashauer , Rainer Rossberg
IPC: F04B4906
CPC classification number: H01L41/00 , B01J2219/00351 , B01J2219/00364 , B01J2219/00378 , B01L3/0265 , B01L3/0268 , B01L3/5027 , B01L2200/146 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406 , B01L2400/0439 , B01L2400/0487 , B05B9/0413 , C40B60/14 , F04B19/006 , F04B43/046 , F04B2201/0201 , G01F11/08 , G01N35/00 , G01N2035/00237
Abstract: A microdosing device comprises a pressure chamber which is at least partly delimited by a displacer, an actuating device for actuating the displacer, the volume of the pressure chamber being adapted to be changed by actuating the displacer, a media reservoir which is in fluid comunication with the pressure chamber via a first fluid line, and an outlet opening which is in fluid communication with the pressure chamber via a second fluid line. The microdosing device additionally comprises a means for detecting the respective position of the displacer and a control means which is connected to the actuating device and to the means for detecting the position of the displacer, said control means controlling the actuating device on the basis of the detected position of the displacer or on the basis of displacer positions detected during at least one preceding dosing cycle so as to cause the discharge of a defined volume of fluid from the outlet opening. The control means comprises means for controlling the actuating device with a signal of low edge steepness so as to cause the displacer to move from a first position to a predetermined second position, the second position of the displacer defining a larger volume of the pressure chamber than the first position. In addition, the control means comprises means for controlling the actuating device with a signal of high edge steepness so as to cause the displacer to move from the second position to the first position for discharging in this way a defined volume of fluid from the outlet opening.
Abstract translation: 微量饮料装置包括至少部分地由置换器限定的压力室,用于致动置换器的致动装置,压力室的体积适于通过致动置换器来改变;压力室的体积可以通过流体通过与 经由第一流体管线的压力室和通过第二流体管线与压力室流体连通的出口开口。 微量计量装置还包括用于检测置换器的相应位置的装置和连接到致动装置的控制装置和用于检测置换器的位置的装置,所述控制装置基于 检测置换器的位置,或者基于在至少一个以前的给料循环期间检测到的置换器位置,以便引起从出口开口排出限定体积的流体。 控制装置包括用于利用低边缘陡度的信号来控制致动装置的装置,以便使置换器从第一位置移动到预定的第二位置,置换器的第二位置限定压力室的体积更大, 第一名。 此外,控制装置包括用于利用具有高边缘陡度的信号来控制致动装置的装置,以便使置换器从第二位置移动到第一位置,以这种方式从出口开口排出限定体积的流体 。
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