公开(公告)号：US08461328B2

公开(公告)日：2013-06-11

申请号：US13004808

申请日：2011-01-11

Applicant: Srinivasan Babu ,  Phillippe Bergeron ,  Peter Dragovich ,  Hazel Joan Dyke ,  Paul Gibbons ,  Stefan Gradl ,  Emily Hanan ,  Christopher Hurley ,  Tony Johnson ,  Michael Koehler ,  Janusz Kulagowski ,  Sharada Labadie ,  Joseph Lyssikatos ,  Rohan Mendonca ,  Rebecca Pulk ,  Stuart Ward ,  Bohdan Waszkowycz ,  Mark Zak

Inventor： Srinivasan Babu ,  Phillippe Bergeron ,  Peter Dragovich ,  Hazel Joan Dyke ,  Paul Gibbons ,  Stefan Gradl ,  Emily Hanan ,  Christopher Hurley ,  Tony Johnson ,  Michael Koehler ,  Janusz Kulagowski ,  Sharada Labadie ,  Joseph Lyssikatos ,  Rohan Mendonca ,  Rebecca Pulk ,  Stuart Ward ,  Bohdan Waszkowycz ,  Mark Zak

IPC: A61P11/06 ,  A61P17/06 ,  A61P19/02 ,  A61P37/06 ,  C07D413/14 ,  C07D471/14

CPC classification number: C07D471/14 ,  C07D487/10

Abstract: The invention provides novel compounds of formula I having the general formula: wherein R1, R2, R3, X and Y are as described herein. Accordingly, the compounds may be provided in pharmaceutically acceptable compositions and used for the treatment of immunological or hyperproliferative disorders.

Abstract translation: 本发明提供具有以下通式的新颖的式I化合物：其中R1，R2，R3，X和Y如本文所述。 因此，化合物可以以药学上可接受的组合物提供，并用于治疗免疫学或过度增殖性疾病。

公开(公告)号：US20090231157A1

公开(公告)日：2009-09-17

申请号：US12403165

申请日：2009-03-12

Applicant: Stuart Ward

Inventor： Stuart Ward

IPC: G08C19/16

CPC classification number: G01K17/003 ,  G01D3/022

Abstract: An adaptor can be provided for a meter of the type comprising a meter body and a detector. The meter body can be operative to process and display an analogue output signal generated by the detector indicative of a given input to the detector. The adaptor can comprise electrical connection means operative to form electrical connections with the meter body and with the detector. The adaptor can further comprise interface means operative to convert, in use, the analogue output signal from the detector into a standardised output signal for transmission to the meter body. The interface means can be operative to generate the standardised output signal from a plurality of detectors such that the adaptor can enable the meter body to be used with more than one detector.

Abstract translation: 可以为一种包括仪表主体和检测器的仪表提供适配器。 仪表主体可操作以处理和显示由检测器产生的模拟输出信号，该模拟输出信号指示给予检测器的给定输入。 适配器可以包括电连接装置，其可操作以与仪表主体和检测器形成电连接。 适配器还可以包括接口装置，其可操作以在使用中将来自检测器的模拟输出信号转换成用于传输到仪表主体的标准化输出信号。 接口装置可以用于从多个检测器产生标准化的输出信号，使得适配器能够使仪表主体与多于一个的检测器一起使用。

公开(公告)号：US06523426B1

公开(公告)日：2003-02-25

申请号：US09646004

申请日：2000-11-17

Applicant: David Robert Vincent ,  John William Proctor ,  Stuart Ward

Inventor： David Robert Vincent ,  John William Proctor ,  Stuart Ward

IPC: G01N3318

CPC classification number: G01N33/18 ,  G01N27/283

Abstract: A device for water quality measurement apparatus includes a plurality of multi-element arrays formed on a substrate, which are immersed in a solution for detecting electroactive elements or compounds present in such a solution. A wafer is located between first and second ‘O’ rings, with the first ‘O’ ring being disposed on a first side of the wafer and the second ‘O’ ring being disposed on a second side of the wafer, opposite to the first side. The first and second ‘O’ rings are arranged such that the wafer is exposed to substantially equal pressure on both sides.

Abstract translation: 一种用于水质测量装置的装置包括形成在基板上的多个多元件阵列，其浸没在用于检测存在于该溶液中的电活性元素或化合物的溶液中。 晶片位于第一和第二“O”环之间，第一“O”环设置在晶片的第一侧上，第二“O”环设置在晶片的第二侧上，与第一 第一和第二“O”环被布置成使得晶片在两侧基本相等的压力下暴露。

公开(公告)号：US20110201593A1

公开(公告)日：2011-08-18

申请号：US13004808

申请日：2011-01-11

Applicant: Srinivasan Babu ,  Phillippe Bergeron ,  Peter Dragovich ,  Hazel Joan Dyke ,  Paul Gibbons ,  Stefan Gradl ,  Emily Hanan ,  Christopher Hurley ,  Tony Johnson ,  Michael Koehler ,  Janusz Kulagowski ,  Sharada Labadie ,  Joseph Lyssikatos ,  Rohan Mendonca ,  Rebecca Pulk ,  Stuart Ward ,  Bohdan Waszkowycz ,  Mark Zak

Inventor： Srinivasan Babu ,  Phillippe Bergeron ,  Peter Dragovich ,  Hazel Joan Dyke ,  Paul Gibbons ,  Stefan Gradl ,  Emily Hanan ,  Christopher Hurley ,  Tony Johnson ,  Michael Koehler ,  Janusz Kulagowski ,  Sharada Labadie ,  Joseph Lyssikatos ,  Rohan Mendonca ,  Rebecca Pulk ,  Stuart Ward ,  Bohdan Waszkowycz ,  Mark Zak

IPC: A61K31/397 ,  C07D471/14 ,  A61K31/437 ,  C07D413/14 ,  A61K31/5377 ,  A61K31/496 ,  A61K31/55 ,  A61K31/506 ,  A61P19/02 ,  A61P17/06 ,  A61P37/06 ,  A61P11/06

CPC classification number: C07D471/14 ,  C07D487/10

Abstract: The invention provides novel compounds of formula I having the general formula: wherein R1, R2, R3, X and Y are as described herein. Accordingly, the compounds may be provided in pharmaceutically acceptable compositions and used for the treatment of immunological or hyperproliferative disorders.

Abstract translation: 本发明提供具有以下通式的新颖的式I化合物：其中R1，R2，R3，X和Y如本文所述。 因此，化合物可以以药学上可接受的组合物提供，并用于治疗免疫学或过度增殖性疾病。

公开(公告)号：US20080218748A1

公开(公告)日：2008-09-11

申请号：US12041399

申请日：2008-03-03

Applicant: John Hewinson ,  Stuart Ward

Inventor： John Hewinson ,  Stuart Ward

IPC: G01J1/44

CPC classification number: G01J1/4257 ,  G01J5/12 ,  G01J2005/066

Abstract: A measuring apparatus comprises a detector device for detecting a variable to be measured, and a controller operative to control the detector device and generate an output signal indicative of the magnitude of the variable being measured. The detector device comprises a housing on which are mounted two Peltier-Seebeck detectors, the detectors being arranged on the housing such that only the first Peltier-Seebeck detector is exposed, in use, to the variable to be measured. The controller is operative to generate the output signal based on the output of the first Peltier-Seebeck detector and the output of the second Peltier-Seebeck detector so as to account for the effect of the ambient heat on each Peltier-Seebeck detector.

Abstract translation: 测量装置包括用于检测待测量的变量的检测器装置，以及控制器，用于控制检测器装置并产生指示所测量的变量的大小的输出信号。 检测器装置包括壳体，其上安装有两个珀耳帖 - 塞贝克检测器，检测器布置在壳体上，使得仅在使用中第一珀尔帖塞贝克检测器暴露于要测量的变量。 控制器可操作以基于第一珀耳帖 - 塞贝克检测器的输出和第二珀尔帖 - 塞贝克检测器的输出来产生输出信号，以便考虑每个珀耳帖 - 塞贝克检测器上的环境热的影响。

公开(公告)号：US5668330A

公开(公告)日：1997-09-16

申请号：US679759

申请日：1996-07-10

Applicant: William Bartlett-Hooker ,  Sanath Ediriweera ,  Stuart Ward

Inventor： William Bartlett-Hooker ,  Sanath Ediriweera ,  Stuart Ward

IPC: G01N1/00 ,  G01N1/36 ,  G01N21/76 ,  G01N33/18

CPC classification number: G01N35/1097 ,  G01N33/1893

Abstract: Toxicity measuring apparatus comprising a sample reservoir in which an aqueous sample to be tested is stored, a reagent reservoir, a diluent reservoir, a mixing chamber vented via a first valve to atmosphere through an air inlet tube which extends within the chamber towards a lower part thereof, second, third and fourth valves via which the sample, the reagent and the diluent respectively are fed selectively to the mixing chamber in accordance with the open/closed state of the said second, third or fourth valves, a toxicity detector cell fed with a mixture of the sample, the reagent and the diluent from the chamber, within which detector cell aqueous sample measurements are carried out, a linear pump and valve means, via which valve means the mixture is drawn through the detector cell from the chamber by the linear pump, or via which air in an upper part of the chamber is drawn from the chamber by the pump in accordance with the open/closed state of the said valve means, whereby for the purpose of mixing the sample, the reagent and the diluent, the said valve means is set so that air is drawn into the chamber via the inlet tube so as to bubble up through the mixture contained therein so as to effect mixing.

Abstract translation: 一种毒性测定装置，其特征在于，包括储存有待测试的水样品的试样储存器，试剂储存器，稀释剂储存器，经由第一阀向大气排出的混合室，该空气入口管在腔室内向下方延伸 第二阀，第三阀和第四阀，根据所述第二，第三或第四阀的打开/关闭状态，将样品，试剂和稀释剂分别选择性地供给到混合室中的毒素检测器单元， 来自腔室的样品，试剂和稀释剂的混合物，在其中进行检测器池水样品测量，线性泵和阀装置，阀通过该装置将混合物从室通过检测器池从 或者通过泵根据所述阀装置的打开/关闭状态从室从腔室中抽出空气，由此，对于th 为了混合样品，试剂和稀释剂，所述阀装置被设置成使得空气经由入口管被吸入室中，以便通过其中包含的混合物起泡以便进行混合。

公开(公告)号：US08416820B1

公开(公告)日：2013-04-09

申请号：US13293013

申请日：2011-11-09

Applicant: Stuart Ward

Inventor： Stuart Ward

IPC: H01S3/00

CPC classification number: H01S3/0014 ,  B23K26/706 ,  F16P1/02

Abstract: An active laser guarding system 1 comprises at least one screen 3 provided with at least two spaced apart conductors 7, 9 each defining a respective electrically conductive path that is electrically separate from the other. The screen 3 comprises material, at least between the two conductors 7, 9, which is arranged to carbonize when struck by a laser beam to form a further conductive path 19 which extends between, and electrically connects, the two conductors 7, 9. The system 1 further comprises a detector 15 operative to detect the further conductive path 19 so formed, the detector 15 being operative to generate a laser deactivation signal response to detecting the further conductive path 19.

Abstract translation: 有源激光防护系统1包括至少一个屏幕3，屏幕3设置有至少两个间隔开的导体7,9，每个导体限定与另一个电气分离的相应导电路径。 屏幕3包括至少在两个导体7,9之间的材料，其被布置成当被激光束撞击时碳化，以形成在两个导体7,9之间延伸并电连接的导电路径19。 系统1还包括检测器15，用于检测如此形成的另外的导电路径19，检测器15可操作以产生激光去激活信号响应，以检测另外的导电路径19。

公开(公告)号：US07954993B2

公开(公告)日：2011-06-07

申请号：US12041399

申请日：2008-03-03

Applicant: John Hewinson ,  Stuart Ward

Inventor： John Hewinson ,  Stuart Ward

IPC: G01K17/00

CPC classification number: G01J1/4257 ,  G01J5/12 ,  G01J2005/066

Abstract: A measuring apparatus comprises a detector device for detecting a variable to be measured, and a controller operative to control the detector device and generate an output signal indicative of the magnitude of the variable being measured. The detector device comprises a housing on which are mounted two Peltier-Seebeck detectors, the detectors being arranged on the housing such that only the first Peltier-Seebeck detector is exposed, in use, to the variable to be measured. The controller is operative to generate the output signal based on the output of the first Peltier-Seebeck detector and the output of the second Peltier-Seebeck detector so as to account for the effect of the ambient heat on each Peltier-Seebeck detector.

Abstract translation: 测量装置包括用于检测待测量的变量的检测器装置，以及控制器，用于控制检测器装置并产生指示所测量的变量的大小的输出信号。 检测器装置包括壳体，其上安装有两个珀耳帖 - 塞贝克检测器，检测器布置在壳体上，使得仅在使用中第一珀尔帖塞贝克检测器暴露于要测量的变量。 控制器可操作以基于第一珀耳帖 - 塞贝克检测器的输出和第二珀尔帖 - 塞贝克检测器的输出来产生输出信号，以便考虑每个珀耳帖 - 塞贝克检测器上的环境热的影响。

公开(公告)号：US5801052A

公开(公告)日：1998-09-01

申请号：US680873

申请日：1996-07-16

Applicant: William Bartlett-Hooker ,  Sanath Ediriweera ,  Stuart Ward

Inventor： William Bartlett-Hooker ,  Sanath Ediriweera ,  Stuart Ward

IPC: C12M1/34 ,  C12M1/00 ,  C12N1/00 ,  C12Q1/02 ,  C12M3/00 ,  B01F15/02

CPC classification number: C12M45/00 ,  C12N1/00

Abstract: An apparatus for reconstituting dried bacteria includes a first reservoir for the storage of reconstituting solution, a pump via which the reservoir is coupled to one of a pair of hollow needles arranged side by side in operative association with an apparatus for raising or lowering the pair so that in use they can be lowered to pierce a closure bung of a container in which bacteria are sealed under vacuum, the one needle being effectively longer than the other of the two hollow needles so that consequent upon lowering of the pair, the one needle passes through the bung before the other effectively shorter of the two needles. The shorter of the two needles is coupled to a second reservoir for the transfer thereto, in use of the apparatus, of reconstitution solution from the first reservoir together with bacteria from the container.

Abstract translation: 用于重构干细菌的装置包括用于储存重构溶液的第一储存器，泵，通过该泵将储存器联接到并排布置的一对空心针中的一个，与用于升高或降低该对的装置可操作地相关联 在使用中，它们可以被降低以刺穿细菌在真空下密封的容器的封闭栓，一个针实际上比两个中空针中的另一个更长，从而随着一对针的下降，一根针通过 通过砰砰之前的另一个有效地更短的两根针。 两个针中较短的一个连接到第二储存器，用于在使用该装置的同时将来自第一储存器的重构溶液与来自容器的细菌一起转移。

公开(公告)号：US20110240042A1

公开(公告)日：2011-10-06

申请号：US13140198

申请日：2009-12-16

Applicant: Matthew William Cooke ,  Stuart Ward

Inventor： Matthew William Cooke ,  Stuart Ward

IPC: A61F5/37

CPC classification number: A61F5/055 ,  A61F5/00 ,  A61F5/01 ,  A61F5/04 ,  A61F5/05883 ,  A61F5/37 ,  A61F5/3707 ,  A61G5/00 ,  A61G5/10 ,  A61G5/12 ,  A61G13/00 ,  A61G13/0036 ,  A61G13/10 ,  A61G13/12 ,  A61G13/1205 ,  A61G13/126

Abstract: A spinal immobilisation apparatus has a harness for immovably securing to the torso of a person and a separate head support of collarless construction for mounting about the head of a person. Releasable connection allows the head support to be adjustably secured on the harness in relation to the shoulders and back of the wearer. The harness configuration allows ready access to the wearer's chest area. Elastication allows the cheat to expand during breathing. The head support is of open-faced, open-topped structure having rigid side walls hingedly connected to a rigid rear wall.

Abstract translation: 脊柱固定装置具有用于不可移动地固定到人的躯干的装置和用于安装在人的头部上的无套环结构的单独头部支撑。 可释放的连接允许头部支撑件可相对于穿戴者的肩部和背部被可调节地固定在线束上。 线束配置允许随时访问佩戴者的胸部区域。 弹力可以让作弊在呼吸过程中扩张。 头部支撑件是敞开的，开放顶部的结构，其刚性侧壁铰接地连接到刚性后壁。